Click here to switch to the map view.

The map label for this gene is yafV [C]

Identifier: 221635917

GI number: 221635917

Start: 501382

End: 502221

Strand: Reverse

Name: yafV [C]

Synonym: trd_A0511

Alternate gene names: 221635917

Gene position: 502221-501382 (Counterclockwise)

Preceding gene: 221635923

Following gene: 221635915

Centisome position: 54.72

GC content: 63.1

Gene sequence:

>840_bases
ATGAGCGACCTTCTCCGGATCGGTCTGGTCCAGATGAACTCCCGCTCGGACAAGAGCGAGAACCTCGCCGTCGCTGAACG
GCTGATCGAAGAAGCGGCCAGGCAAGGGGCCGAACTCGTCGCTCTGCCCGAGTACGTCAACTTTCTCGGACCCCGCGAAC
TCCACGAAGCGAACGCCGAGCCGATTCCCGGTCCGACCACCGAGCGGTTCGCAGCGCTCGCCCGTCGCTACGGCATCTAT
CTGCTGGGCGGCTCGATCCTCGAGCGCTCGGCCATCCCCGGCAAGTACTACAACACGAGTGTTCTTTTCGCGCCCGACGG
CGAGATCATCGCCAGTTACCGCAAGATCCATCTCTTCGACGTCGATCTCACCGGTAACGTGACCAGCAACGAGTCGGCGA
CCATCTTGCCCGGTGACCGGGTGGTAACGGCCGAAGTCGCTGGGCACGTAGTCGGGCTGACCATCTGCTACGACCTGCGC
TTCCCCGAACTCTATCGCCTGCTCGCACTCGACGGAGCCGAACTGATCCTCGTCCCTGCCGCTTTCACGCTTTACACCGG
TAAGGACCACTGGCACACCCTGCTACGCGCGCGAGCGATCGAGAACCAGTGCTACGTTGCGGCCCCAGCGCAGATCGGCC
CACACGATCCAGGGCAACAGTGCTATGGCCACTCCCTCGTCGCCGACCCCTGGGGAACCGTCATCGCCGAGGCGATCAAT
CGTGTCGGTGTGGTTGTCACGACGCTGGACTTCGCCTATCTCCGCGAAGTACGAGCCCAGCTACCGTCGCTGGCCAATCG
CCGACCGGAAACCTATGGAAGTCTCGCTCTGACACGCTGA

Upstream 100 bases:

>100_bases
AGCGAGTCAGCGACCGTCCTCCTGTGCACTGCACAGGTACCGTGTTTCCGCAGTACAATGCGGCGAGTGGATCGCTCGAC
GAAGCAGAGAGGAGACCGCC

Downstream 100 bases:

>100_bases
ACCGGGTGAGAGACCCGCTGCGTGGGCTGGACCGATCGTACCAGTTCGCCCGGTCCAGCCCACGCGCTCTTCCCGGGTAG
TCCAAGACAGATGCGCCGAC

Product: hydrolase, carbon-nitrogen family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 279; Mature: 278

Protein sequence:

>279_residues
MSDLLRIGLVQMNSRSDKSENLAVAERLIEEAARQGAELVALPEYVNFLGPRELHEANAEPIPGPTTERFAALARRYGIY
LLGGSILERSAIPGKYYNTSVLFAPDGEIIASYRKIHLFDVDLTGNVTSNESATILPGDRVVTAEVAGHVVGLTICYDLR
FPELYRLLALDGAELILVPAAFTLYTGKDHWHTLLRARAIENQCYVAAPAQIGPHDPGQQCYGHSLVADPWGTVIAEAIN
RVGVVVTTLDFAYLREVRAQLPSLANRRPETYGSLALTR

Sequences:

>Translated_279_residues
MSDLLRIGLVQMNSRSDKSENLAVAERLIEEAARQGAELVALPEYVNFLGPRELHEANAEPIPGPTTERFAALARRYGIY
LLGGSILERSAIPGKYYNTSVLFAPDGEIIASYRKIHLFDVDLTGNVTSNESATILPGDRVVTAEVAGHVVGLTICYDLR
FPELYRLLALDGAELILVPAAFTLYTGKDHWHTLLRARAIENQCYVAAPAQIGPHDPGQQCYGHSLVADPWGTVIAEAIN
RVGVVVTTLDFAYLREVRAQLPSLANRRPETYGSLALTR
>Mature_278_residues
SDLLRIGLVQMNSRSDKSENLAVAERLIEEAARQGAELVALPEYVNFLGPRELHEANAEPIPGPTTERFAALARRYGIYL
LGGSILERSAIPGKYYNTSVLFAPDGEIIASYRKIHLFDVDLTGNVTSNESATILPGDRVVTAEVAGHVVGLTICYDLRF
PELYRLLALDGAELILVPAAFTLYTGKDHWHTLLRARAIENQCYVAAPAQIGPHDPGQQCYGHSLVADPWGTVIAEAINR
VGVVVTTLDFAYLREVRAQLPSLANRRPETYGSLALTR

Specific function: Unknown

COG id: COG0388

COG function: function code R; Predicted amidohydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 CN hydrolase domain [H]

Homologues:

Organism=Homo sapiens, GI9910460, Length=269, Percent_Identity=42.3791821561338, Blast_Score=224, Evalue=7e-59,
Organism=Homo sapiens, GI297632350, Length=282, Percent_Identity=41.8439716312057, Blast_Score=212, Evalue=3e-55,
Organism=Homo sapiens, GI297632348, Length=282, Percent_Identity=41.8439716312057, Blast_Score=212, Evalue=3e-55,
Organism=Homo sapiens, GI5031947, Length=281, Percent_Identity=41.9928825622776, Blast_Score=212, Evalue=3e-55,
Organism=Homo sapiens, GI297632346, Length=197, Percent_Identity=38.0710659898477, Blast_Score=124, Evalue=1e-28,
Organism=Escherichia coli, GI1786412, Length=268, Percent_Identity=29.4776119402985, Blast_Score=69, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17556280, Length=269, Percent_Identity=39.7769516728625, Blast_Score=200, Evalue=6e-52,
Organism=Saccharomyces cerevisiae, GI6323383, Length=282, Percent_Identity=35.8156028368794, Blast_Score=178, Evalue=1e-45,
Organism=Saccharomyces cerevisiae, GI6322335, Length=307, Percent_Identity=33.5504885993485, Blast_Score=155, Evalue=7e-39,
Organism=Drosophila melanogaster, GI21355835, Length=278, Percent_Identity=35.9712230215827, Blast_Score=186, Evalue=1e-47,
Organism=Drosophila melanogaster, GI17933642, Length=272, Percent_Identity=38.9705882352941, Blast_Score=182, Evalue=2e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003010
- InterPro:   IPR001110 [H]

Pfam domain/function: PF00795 CN_hydrolase [H]

EC number: 3.5.-.- [C]

Molecular weight: Translated: 30568; Mature: 30437

Theoretical pI: Translated: 5.62; Mature: 5.62

Prosite motif: PS50263 CN_HYDROLASE ; PS01227 UPF0012

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDLLRIGLVQMNSRSDKSENLAVAERLIEEAARQGAELVALPEYVNFLGPRELHEANAE
CCCHHHHHEEEECCCCCCCCHHHHHHHHHHHHHHCCCEEEECHHHHHHCCCHHHHHCCCC
PIPGPTTERFAALARRYGIYLLGGSILERSAIPGKYYNTSVLFAPDGEIIASYRKIHLFD
CCCCCCHHHHHHHHHHCCEEEECCHHHHHCCCCCCCCCCEEEECCCCHHHCCEEEEEEEE
VDLTGNVTSNESATILPGDRVVTAEVAGHVVGLTICYDLRFPELYRLLALDGAELILVPA
EEEECCCCCCCCEEEECCCEEEEHHHCCCEEEEEEEEECCCHHHHHHHHCCCCCEEEEEE
AFTLYTGKDHWHTLLRARAIENQCYVAAPAQIGPHDPGQQCYGHSLVADPWGTVIAEAIN
EEEEECCCHHHHHHHHHHHHCCCEEEEECCCCCCCCCCHHHHCCCEECCCHHHHHHHHHH
RVGVVVTTLDFAYLREVRAQLPSLANRRPETYGSLALTR
HCEEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECC
>Mature Secondary Structure 
SDLLRIGLVQMNSRSDKSENLAVAERLIEEAARQGAELVALPEYVNFLGPRELHEANAE
CCHHHHHEEEECCCCCCCCHHHHHHHHHHHHHHCCCEEEECHHHHHHCCCHHHHHCCCC
PIPGPTTERFAALARRYGIYLLGGSILERSAIPGKYYNTSVLFAPDGEIIASYRKIHLFD
CCCCCCHHHHHHHHHHCCEEEECCHHHHHCCCCCCCCCCEEEECCCCHHHCCEEEEEEEE
VDLTGNVTSNESATILPGDRVVTAEVAGHVVGLTICYDLRFPELYRLLALDGAELILVPA
EEEECCCCCCCCEEEECCCEEEEHHHCCCEEEEEEEEECCCHHHHHHHHCCCCCEEEEEE
AFTLYTGKDHWHTLLRARAIENQCYVAAPAQIGPHDPGQQCYGHSLVADPWGTVIAEAIN
EEEEECCCHHHHHHHHHHHHCCCEEEEECCCCCCCCCCHHHHCCCEECCCHHHHHHHHHH
RVGVVVTTLDFAYLREVRAQLPSLANRRPETYGSLALTR
HCEEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]