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The map label for this gene is eat [C]

Identifier: 221635834

GI number: 221635834

Start: 413652

End: 415190

Strand: Reverse

Name: eat [C]

Synonym: trd_A0428

Alternate gene names: 221635834

Gene position: 415190-413652 (Counterclockwise)

Preceding gene: 221635835

Following gene: 221635833

Centisome position: 45.24

GC content: 63.03

Gene sequence:

>1539_bases
ATGGGTGAGCAACCGACGATCGAGCGCGGCGGGGTCCGCTACGAGCGAGTCGGACAGGAGTATCTCGAGCAACGCAAACT
TCGCCGCCATGCCAACTGGGTGCTTCTCTGGGCGCTCGGGGTGGGAGCGGTCATCTCCGGTGACTTCTTCGGCTGGAACT
TCGGCCTGAGTGCTGGCGGCTTCGGCGGTCTCCTCATCGCGACCGTGCTCATGGCGCTGATGTACCTCTTCATGGTGTAC
AGCATCGCTGAGCTGACGACCGCCCTGCCCCACGCAGGCGGCTTCTACTCGTTCACGCGCAGCGCCTTCGGTCCGTGGGG
AGGCTACCTCGTCGGCGTCACCGACACCATCGAGTACGTCATCACTCCAGCGGTGATCGTGGTCGGGATCGGTGGCTACA
TGAATACCCTGTTCCCGCAGGTCCCGGTCTGGCTCTGGTGGCTCTTGTTCTACATGGTCTTCGTCGCTATCAATATCGCT
GGTGTCGAGATCACCCTGCGCGTCGGACTCGTCGTCACCATTCTCGCCATGCTCATCCTCGTGATCTTCTACATCGGCGC
GGTCGCCAGCGGCGCTTTCAGCTGGGATCTCGTCTTCAACATCGAACCCAATCCTGACCGAGCCGGTAGCTCGACCTTCT
TGCCGCAAGGCTTCTTCGGCATCTTCGCGGCCATCCCCTTCGCCATCTGGTTCTACCTCGCGATCGAGGAACTGCCCTTG
GCCGCCGAAGAGACTCACGATGTCGTCCGTGACATGCCGAAGGGCCTCATCACTGGTATCTTCACACTGCTCGCGTTGTC
GGTCTTCACGCTCGTCTTCAACTCCGGCGTCAACGGCGGAGCCAAGCAAATCGGCGAGTCGAGTGCGCCCTTGGCCGATG
GCTTCCAGGCGGTCTTCGGTGCCGGAGCGACGACGACGGTGCTGACGCTCATCGCCCTCACCGGACTGATCGCGAGCTTC
CACACCATCATCTATGCCTACGGCCGGGTCATTTTCGCCCTCTCGCGCGCCGGCTACTACCCGCGCTTCCTCTCGGTGAC
CAGCCCGAAGACGCACACGCCGCACCGGGCACTCATCGCCGGCGCCATCATCGGTCTCCTCTGCGCAGTGATCATCGACC
AGTTCGGAACCGGCATCGTCGGTGCCGCGCTCCTCAACATGGCGGTCTTCGGCGCAGTCATTTCCTATGCCGCGGTGATG
CTCGCCTACATCCGCCTCAAGATCACCCGCCCCGACTTGCCACGCCCGTACAAGAGCCCCTTCGGGATTCCGGGCGCAGC
CATCGGTGCCGCCCTGGCCATCCTTGCTCTGTTCGCGACCTTCTCCATCCAGGACTACCGCCCAGGCGTGCTGGGTGTCG
CCTTCTTCCTCGTGATCGCCCTCCTCTACTTCGCCCTGTATTCGCGGCATCGCCTGGTCGCCCAGGCACCGGAAGAGGAG
GTCGCGCTCATCTTGGAAGCCGAAAAGGAGCTCAAGCACCAGTACGTGGAGCTCGAATCGGAGGAAGAGCGGCGTCGCAT
GGAGGAGCAGGCGCGGTAA

Upstream 100 bases:

>100_bases
CTATGTGACCGCGACAGCGTTCCTGGTCGATGGCGGCATCACCGCCGCCTACATCACACCGGAAGAGTGATCAGCGAGTC
AACGAGAGGAGGGAAGCGAG

Downstream 100 bases:

>100_bases
GACGCGCCGATCCTCAACCCATGAGCCGGCTCGGCGCGGTCGACTGCGCGGTCGATCCGCGCCGAGTCTTTTGTCCGCCC
CGCCTCTTGCGACAGGCGAG

Product: ethanolamine permease

Products: D-glycine [Cytoplasm]; D-alanine [Cytoplasm]; Proton [Cytoplasm]; D-serine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 512; Mature: 511

Protein sequence:

>512_residues
MGEQPTIERGGVRYERVGQEYLEQRKLRRHANWVLLWALGVGAVISGDFFGWNFGLSAGGFGGLLIATVLMALMYLFMVY
SIAELTTALPHAGGFYSFTRSAFGPWGGYLVGVTDTIEYVITPAVIVVGIGGYMNTLFPQVPVWLWWLLFYMVFVAINIA
GVEITLRVGLVVTILAMLILVIFYIGAVASGAFSWDLVFNIEPNPDRAGSSTFLPQGFFGIFAAIPFAIWFYLAIEELPL
AAEETHDVVRDMPKGLITGIFTLLALSVFTLVFNSGVNGGAKQIGESSAPLADGFQAVFGAGATTTVLTLIALTGLIASF
HTIIYAYGRVIFALSRAGYYPRFLSVTSPKTHTPHRALIAGAIIGLLCAVIIDQFGTGIVGAALLNMAVFGAVISYAAVM
LAYIRLKITRPDLPRPYKSPFGIPGAAIGAALAILALFATFSIQDYRPGVLGVAFFLVIALLYFALYSRHRLVAQAPEEE
VALILEAEKELKHQYVELESEEERRRMEEQAR

Sequences:

>Translated_512_residues
MGEQPTIERGGVRYERVGQEYLEQRKLRRHANWVLLWALGVGAVISGDFFGWNFGLSAGGFGGLLIATVLMALMYLFMVY
SIAELTTALPHAGGFYSFTRSAFGPWGGYLVGVTDTIEYVITPAVIVVGIGGYMNTLFPQVPVWLWWLLFYMVFVAINIA
GVEITLRVGLVVTILAMLILVIFYIGAVASGAFSWDLVFNIEPNPDRAGSSTFLPQGFFGIFAAIPFAIWFYLAIEELPL
AAEETHDVVRDMPKGLITGIFTLLALSVFTLVFNSGVNGGAKQIGESSAPLADGFQAVFGAGATTTVLTLIALTGLIASF
HTIIYAYGRVIFALSRAGYYPRFLSVTSPKTHTPHRALIAGAIIGLLCAVIIDQFGTGIVGAALLNMAVFGAVISYAAVM
LAYIRLKITRPDLPRPYKSPFGIPGAAIGAALAILALFATFSIQDYRPGVLGVAFFLVIALLYFALYSRHRLVAQAPEEE
VALILEAEKELKHQYVELESEEERRRMEEQAR
>Mature_511_residues
GEQPTIERGGVRYERVGQEYLEQRKLRRHANWVLLWALGVGAVISGDFFGWNFGLSAGGFGGLLIATVLMALMYLFMVYS
IAELTTALPHAGGFYSFTRSAFGPWGGYLVGVTDTIEYVITPAVIVVGIGGYMNTLFPQVPVWLWWLLFYMVFVAINIAG
VEITLRVGLVVTILAMLILVIFYIGAVASGAFSWDLVFNIEPNPDRAGSSTFLPQGFFGIFAAIPFAIWFYLAIEELPLA
AEETHDVVRDMPKGLITGIFTLLALSVFTLVFNSGVNGGAKQIGESSAPLADGFQAVFGAGATTTVLTLIALTGLIASFH
TIIYAYGRVIFALSRAGYYPRFLSVTSPKTHTPHRALIAGAIIGLLCAVIIDQFGTGIVGAALLNMAVFGAVISYAAVML
AYIRLKITRPDLPRPYKSPFGIPGAAIGAALAILALFATFSIQDYRPGVLGVAFFLVIALLYFALYSRHRLVAQAPEEEV
ALILEAEKELKHQYVELESEEERRRMEEQAR

Specific function: Probable amino-acid or metabolite transport protein [H]

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Homo sapiens, GI33286428, Length=511, Percent_Identity=23.679060665362, Blast_Score=71, Evalue=3e-12,
Organism=Homo sapiens, GI258645169, Length=456, Percent_Identity=24.780701754386, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI258614003, Length=456, Percent_Identity=24.5614035087719, Blast_Score=67, Evalue=4e-11,
Organism=Homo sapiens, GI258614005, Length=456, Percent_Identity=24.5614035087719, Blast_Score=67, Evalue=4e-11,
Organism=Escherichia coli, GI1786302, Length=403, Percent_Identity=21.8362282878412, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI1790653, Length=423, Percent_Identity=23.4042553191489, Blast_Score=89, Evalue=9e-19,
Organism=Escherichia coli, GI1786602, Length=404, Percent_Identity=21.2871287128713, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1788480, Length=444, Percent_Identity=24.0990990990991, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI87081708, Length=367, Percent_Identity=25.3405994550409, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI87081869, Length=384, Percent_Identity=24.4791666666667, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1786789, Length=429, Percent_Identity=22.3776223776224, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI87081915, Length=393, Percent_Identity=22.64631043257, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1789017, Length=394, Percent_Identity=21.5736040609137, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17532491, Length=366, Percent_Identity=25.4098360655738, Blast_Score=69, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6324061, Length=513, Percent_Identity=21.0526315789474, Blast_Score=74, Evalue=5e-14,
Organism=Saccharomyces cerevisiae, GI6321629, Length=449, Percent_Identity=21.826280623608, Blast_Score=66, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6324059, Length=479, Percent_Identity=21.0855949895616, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 55686; Mature: 55555

Theoretical pI: Translated: 6.32; Mature: 6.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGEQPTIERGGVRYERVGQEYLEQRKLRRHANWVLLWALGVGAVISGDFFGWNFGLSAGG
CCCCCCCHHCCCHHHHHHHHHHHHHHHHHHCCEEEEHHHHHHHHHCCCCCCEECCCCCCC
FGGLLIATVLMALMYLFMVYSIAELTTALPHAGGFYSFTRSAFGPWGGYLVGVTDTIEYV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCEEEEHHHHHHHH
ITPAVIVVGIGGYMNTLFPQVPVWLWWLLFYMVFVAINIAGVEITLRVGLVVTILAMLIL
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEHHHHHHHHHHHHHHH
VIFYIGAVASGAFSWDLVFNIEPNPDRAGSSTFLPQGFFGIFAAIPFAIWFYLAIEELPL
HHHHHHHHHCCCEEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
AAEETHDVVRDMPKGLITGIFTLLALSVFTLVFNSGVNGGAKQIGESSAPLADGFQAVFG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCHHHHHHHHHC
AGATTTVLTLIALTGLIASFHTIIYAYGRVIFALSRAGYYPRFLSVTSPKTHTPHRALIA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCHHHHHH
GAIIGLLCAVIIDQFGTGIVGAALLNMAVFGAVISYAAVMLAYIRLKITRPDLPRPYKSP
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCC
FGIPGAAIGAALAILALFATFSIQDYRPGVLGVAFFLVIALLYFALYSRHRLVAQAPEEE
CCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHCCCHHH
VALILEAEKELKHQYVELESEEERRRMEEQAR
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCC
>Mature Secondary Structure 
GEQPTIERGGVRYERVGQEYLEQRKLRRHANWVLLWALGVGAVISGDFFGWNFGLSAGG
CCCCCCHHCCCHHHHHHHHHHHHHHHHHHCCEEEEHHHHHHHHHCCCCCCEECCCCCCC
FGGLLIATVLMALMYLFMVYSIAELTTALPHAGGFYSFTRSAFGPWGGYLVGVTDTIEYV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCEEEEHHHHHHHH
ITPAVIVVGIGGYMNTLFPQVPVWLWWLLFYMVFVAINIAGVEITLRVGLVVTILAMLIL
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEHHHHHHHHHHHHHHH
VIFYIGAVASGAFSWDLVFNIEPNPDRAGSSTFLPQGFFGIFAAIPFAIWFYLAIEELPL
HHHHHHHHHCCCEEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
AAEETHDVVRDMPKGLITGIFTLLALSVFTLVFNSGVNGGAKQIGESSAPLADGFQAVFG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCHHHHHHHHHC
AGATTTVLTLIALTGLIASFHTIIYAYGRVIFALSRAGYYPRFLSVTSPKTHTPHRALIA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCHHHHHH
GAIIGLLCAVIIDQFGTGIVGAALLNMAVFGAVISYAAVMLAYIRLKITRPDLPRPYKSP
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCC
FGIPGAAIGAALAILALFATFSIQDYRPGVLGVAFFLVIALLYFALYSRHRLVAQAPEEE
CCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHCCCHHH
VALILEAEKELKHQYVELESEEERRRMEEQAR
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: D-glycine [Periplasm]; D-alanine [Periplasm]; Proton [Periplasm]; D-serine [Periplasm] [C]

Specific reaction: Proton [Periplasm] + D-glycine [Periplasm] = Proton [Cytoplasm] + D-glycine [Cytoplasm] Proton [Periplasm] + D-alanine [Periplasm] = Proton [Cytoplasm] + D-alanine [Cytoplasm] Proton [Periplasm] + D-serine [Periplasm] = Proton [Cytoplasm] + D-serine [Cyto

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11481430 [H]