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The map label for this gene is Ena [H]

Identifier: 221635741

GI number: 221635741

Start: 322390

End: 323571

Strand: Reverse

Name: Ena [H]

Synonym: trd_A0335

Alternate gene names: 221635741

Gene position: 323571-322390 (Counterclockwise)

Preceding gene: 221635742

Following gene: 221635740

Centisome position: 35.26

GC content: 61.68

Gene sequence:

>1182_bases
ATGCGGCTCGCACTGATAAACATCGGTTGCCTTTTTACTGGAGATATCAACAACCCCCTCCTCCCGGACTGCGACACCGT
GATCGTCGAAGACGGGACGATCACCCAGATCGGAAAGTTCTCCGATCTCGCCGCGGAAGTCGAACAGGCCTCGACAGTCG
TGGACGTCAACGGCATGACTGTCGCGCCGGGGCTCATCGATTCGCATTGCCACGTGGTTCTCGGTGATTACACGCCAAGG
CAAAAGTGCGTGGACTTTCTGGACAGTTACGTTCATGGAGGCGTCACCGCAGTCGTCTCTGCCTCTGAGGTTCACGCGCC
GGGTCGACCCCATGATCGACACGCTGTCATGGGACTGGCTATCGCTGCGCACCACTGCTTCAAGCATTTTCGGCCGAACG
GCATGAAGGTCTTTGCCGGAAGCATCATCCTCGAGCCGTTCCTGACCGAAGAGGACCTGCACTACGTCGCTGCGGCCGGC
GTCCGCTACGCGAAGTTCGGCTTCGGTGCATACGACGATCCACGCGAGGGAGAACCACAAGTCCGCTGGGCGAAAGCTGC
CGGGCTCGTCGTCATGTCCCACTGCGGCGGCGCAAGCATCCCGGGGTCGCAGCCCATTCTGGCCGAACACCTCGTCGTTC
TTCAGCCACACGTACTCGGCCACATCAATGGCGGTCCGACCTCGTTGCCCGACGAGGATATCGAGCTACTCGTCACGCAG
ACAGATATGGCTCTCCAGCTTGTGCAAGCCGGCAATCTGCGCTCGGCCTTGCGCATCGTCGAACTCGCTCACCAGACAGG
CAACCTGCACCGCGTCCTCGTCGCCACCGATACACCGACAGGCACGGGAGTCATGCCTCTGGGAATGGTGAAGTCGATCG
CGGAACTTTCCTCGCTGTCGAGCACCCCGCCAGAGATCGTGTGGTCATGGGCGACCGGAAACAATGCCGATGCGTTTCGG
CTCCCGACCGGCAAGATCGCGGCGGGCTGGCCGGCTGACCTCGTCGTGATCGATGCTCCATGGGGATCGGTCGCCACTGA
TGCTGCGGGGGCTCTCCGCCGCGGCGACATCCCGGGGATTGCAGCCGTCATCATCGATGGTGCGATCCGGACACGCCGAA
GCCGCAATACACCCCCCTCACGTCGTGAGGTGCTCGTGAAGGAGAGAGGAAGTAACCCATGA

Upstream 100 bases:

>100_bases
TGTCGCCGTCGCTAATCGTGGTCGGTTGTTCCATCGCCTCGGCGGGCTGTCAAAGGCGGAAGCGCTCCAGCGGACTACAG
AGAAGTAAGGAGAACACTCC

Downstream 100 bases:

>100_bases
ATAATCATTTTCCCTATCAGAAGATCCGAATTCAGCAAGAGAATAATGTCACCGTGCTCACGCTTGCAGATCCCGACACC
CATAATGCTCTTTCCAATGA

Product: amidohydrolase 3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 393; Mature: 393

Protein sequence:

>393_residues
MRLALINIGCLFTGDINNPLLPDCDTVIVEDGTITQIGKFSDLAAEVEQASTVVDVNGMTVAPGLIDSHCHVVLGDYTPR
QKCVDFLDSYVHGGVTAVVSASEVHAPGRPHDRHAVMGLAIAAHHCFKHFRPNGMKVFAGSIILEPFLTEEDLHYVAAAG
VRYAKFGFGAYDDPREGEPQVRWAKAAGLVVMSHCGGASIPGSQPILAEHLVVLQPHVLGHINGGPTSLPDEDIELLVTQ
TDMALQLVQAGNLRSALRIVELAHQTGNLHRVLVATDTPTGTGVMPLGMVKSIAELSSLSSTPPEIVWSWATGNNADAFR
LPTGKIAAGWPADLVVIDAPWGSVATDAAGALRRGDIPGIAAVIIDGAIRTRRSRNTPPSRREVLVKERGSNP

Sequences:

>Translated_393_residues
MRLALINIGCLFTGDINNPLLPDCDTVIVEDGTITQIGKFSDLAAEVEQASTVVDVNGMTVAPGLIDSHCHVVLGDYTPR
QKCVDFLDSYVHGGVTAVVSASEVHAPGRPHDRHAVMGLAIAAHHCFKHFRPNGMKVFAGSIILEPFLTEEDLHYVAAAG
VRYAKFGFGAYDDPREGEPQVRWAKAAGLVVMSHCGGASIPGSQPILAEHLVVLQPHVLGHINGGPTSLPDEDIELLVTQ
TDMALQLVQAGNLRSALRIVELAHQTGNLHRVLVATDTPTGTGVMPLGMVKSIAELSSLSSTPPEIVWSWATGNNADAFR
LPTGKIAAGWPADLVVIDAPWGSVATDAAGALRRGDIPGIAAVIIDGAIRTRRSRNTPPSRREVLVKERGSNP
>Mature_393_residues
MRLALINIGCLFTGDINNPLLPDCDTVIVEDGTITQIGKFSDLAAEVEQASTVVDVNGMTVAPGLIDSHCHVVLGDYTPR
QKCVDFLDSYVHGGVTAVVSASEVHAPGRPHDRHAVMGLAIAAHHCFKHFRPNGMKVFAGSIILEPFLTEEDLHYVAAAG
VRYAKFGFGAYDDPREGEPQVRWAKAAGLVVMSHCGGASIPGSQPILAEHLVVLQPHVLGHINGGPTSLPDEDIELLVTQ
TDMALQLVQAGNLRSALRIVELAHQTGNLHRVLVATDTPTGTGVMPLGMVKSIAELSSLSSTPPEIVWSWATGNNADAFR
LPTGKIAAGWPADLVVIDAPWGSVATDAAGALRRGDIPGIAAVIIDGAIRTRRSRNTPPSRREVLVKERGSNP

Specific function: Decyclization of 6-oxo-1,4,5,6-tetrahydronicotinate to form 2-(enamine)glutarate, followed by hydrolysis to form (S)-2- formylglutarate [H]

COG id: COG1574

COG function: function code R; Predicted metal-dependent hydrolase with the TIM-barrel fold

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the adenine deaminase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.2.18 [H]

Molecular weight: Translated: 41674; Mature: 41674

Theoretical pI: Translated: 6.19; Mature: 6.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLALINIGCLFTGDINNPLLPDCDTVIVEDGTITQIGKFSDLAAEVEQASTVVDVNGMT
CEEEEEEEEEEEECCCCCCCCCCCCEEEECCCCEEECCCHHHHHHHHHHCCEEEEECCEE
VAPGLIDSHCHVVLGDYTPRQKCVDFLDSYVHGGVTAVVSASEVHAPGRPHDRHAVMGLA
ECCCCCCCCCEEEECCCCCHHHHHHHHHHHHCCCEEEEEEHHHCCCCCCCCCCHHHHHHH
IAAHHCFKHFRPNGMKVFAGSIILEPFLTEEDLHYVAAAGVRYAKFGFGAYDDPREGEPQ
HHHHHHHHHCCCCCEEEEECEEEECCCCCCCHHHHHHHCCCEEEECCCCCCCCCCCCCCC
VRWAKAAGLVVMSHCGGASIPGSQPILAEHLVVLQPHVLGHINGGPTSLPDEDIELLVTQ
EEEEHHCCEEEEECCCCCCCCCCCCHHHHHHEEECCCEEEEECCCCCCCCCCCEEEEEEC
TDMALQLVQAGNLRSALRIVELAHQTGNLHRVLVATDTPTGTGVMPLGMVKSIAELSSLS
CHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHCC
STPPEIVWSWATGNNADAFRLPTGKIAAGWPADLVVIDAPWGSVATDAAGALRRGDIPGI
CCCCCEEEEECCCCCCCEEECCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHCCCCCCE
AAVIIDGAIRTRRSRNTPPSRREVLVKERGSNP
EEEEEHHHHHHHHCCCCCCHHHHHHHHHCCCCC
>Mature Secondary Structure
MRLALINIGCLFTGDINNPLLPDCDTVIVEDGTITQIGKFSDLAAEVEQASTVVDVNGMT
CEEEEEEEEEEEECCCCCCCCCCCCEEEECCCCEEECCCHHHHHHHHHHCCEEEEECCEE
VAPGLIDSHCHVVLGDYTPRQKCVDFLDSYVHGGVTAVVSASEVHAPGRPHDRHAVMGLA
ECCCCCCCCCEEEECCCCCHHHHHHHHHHHHCCCEEEEEEHHHCCCCCCCCCCHHHHHHH
IAAHHCFKHFRPNGMKVFAGSIILEPFLTEEDLHYVAAAGVRYAKFGFGAYDDPREGEPQ
HHHHHHHHHCCCCCEEEEECEEEECCCCCCCHHHHHHHCCCEEEECCCCCCCCCCCCCCC
VRWAKAAGLVVMSHCGGASIPGSQPILAEHLVVLQPHVLGHINGGPTSLPDEDIELLVTQ
EEEEHHCCEEEEECCCCCCCCCCCCHHHHHHEEECCCEEEEECCCCCCCCCCCEEEEEEC
TDMALQLVQAGNLRSALRIVELAHQTGNLHRVLVATDTPTGTGVMPLGMVKSIAELSSLS
CHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHCC
STPPEIVWSWATGNNADAFRLPTGKIAAGWPADLVVIDAPWGSVATDAAGALRRGDIPGI
CCCCCEEEEECCCCCCCEEECCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHCCCCCCE
AAVIIDGAIRTRRSRNTPPSRREVLVKERGSNP
EEEEEHHHHHHHHCCCCCCHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA