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The map label for this gene is cad [H]

Identifier: 221633557

GI number: 221633557

Start: 1565537

End: 1567024

Strand: Reverse

Name: cad [H]

Synonym: trd_1581

Alternate gene names: 221633557

Gene position: 1567024-1565537 (Counterclockwise)

Preceding gene: 221633559

Following gene: 221633551

Centisome position: 78.23

GC content: 70.9

Gene sequence:

>1488_bases
GTGTCGGAGGAACAACAGCGGGCGCCCTATCTGGAACAGTGGTTAGCCTACGTCGATGAGTGCGTGATTCCCTTCACGAC
GCCTGGGCACAAGCAGGGACGCGGTGCACCCCCGGAGTTCGTGGCTGCCTTCGGTGAGCGCGCGCTCGCGCTAGACATTC
CGCATGATGGCGGTACCTTCGATGCGCATCTGGAGCACGATCCGCTGGTTGCGGCCGAGCGCCTGGCGGCTGCCTTGTGG
GGTGCCCGGGACGCCGTCTTCCTGGTCAATGGGAGCACCACCGGCAACCTGGCCGCGCTCTTGACGCTTGGCCGACCCGG
CCAGCCGATCGTCGTGACGCGGGCGATGCACAAGTCGCTCCTGGCCGGGCTGGTGCTGAGCGGTGCCCGACCGGTGTACG
TGGTCCCAGCGGTTCATCCGGAGTCCGGTATCTTGCTCGACCTGCCGCCCGAGTCGGTCGCGCAGGCGCTCGCCGCGTGG
CCGGACGCGACGGCGGTCGCGCTGGTCAGCCCGACGTATACCGGAGTGACGAGCGACACGGCGGAGCTCGCCGCGCTCTG
CCATGCCCACGGTGTCCCTCTCTTTGTCGACGAGGCGTGGGGACCGCATCTTCCCTTCCATCCTGCCTTGCCCGCGGCGG
CCATCCCGTCGGGTGCGGACCTGGCGGTGACCAGCCTGCACAAGCTGGCAGGGTCGCTGACGCAAACCGCACTCCTGCTC
ATGGCGGGAAATCTGGTGGACCAGGCGCAGCTCCGCGCGGCGACTGCGATGGTGCAGACGACCAGTCCGGCCGCTTTCCT
CTACGCATCGCTCGATGCGGCGCGTCGTCGGCTGGCGCTGGAAGGAGAGCAGCTCCTGGCGCGCACACTCGAGCTGGCCG
AGCATGCCCGGCGGGAGCTGGCCGCGATCCCCGGGCTCGAGGTCGTCGGGCCGGAGATCGTCGCTGGGCGGCCGGGAGCA
GGCTTCGATCGGACGCGGCTGGTCGTGGACGTGCAGGGGTTCGGGTTGACCGGTCTGGAGGTCAAGCGGATCCTTCGACG
CGACTTCCGGATCGCGGCCGAGATGGCTGATCTGGTGAGCGTCGTCTTCCTGATCACGATCGGCGACACGCCGGAGACGA
TCGCGGCCCTGGTCGCTGCCTTCCGTGCGCTCGCGGCCGATCGCACCCGGCCAGATTGCGCAGCCGGGCGGCGTGCGGTG
CGGGCGCTCTTGCGCTCCACCGGGCCGATCGTGGCGGGCGCGCCCCAGGCGATGACGCCGCGGGAGGCGTTCTTCGCCCC
AGCCGAGCGAGTGCCGCTCGCTGACGCGGTGGGGCGCGTCGCCGCCGAGCCGGTCACCCCGTATCCGCCAGGGATCCCGG
TGCTGGCCCCGGGCGAGGTGGTCAGGCCGGAGGTCGTCGAGTTCCTCCAGGCCGGGCGCGCGGCCGGGATGCGGTTCAAC
GGTGCCAGCGACCCGACGCTGGCCACGCTGCGCGTCGTGCGTGCCTGA

Upstream 100 bases:

>100_bases
ATTATGCACGCGTCTCCGTCCCCTGTCTACAGGGCACAGCGATCGTGCCCCGGGGGGTATACTCACCCATCCGGTGGGCA
GGAGCGCGGAGGGCGGTGGA

Downstream 100 bases:

>100_bases
CGCGCTGGCCGGGTGAGACGGGGTCACTCGTTTCCACCGGGCGGATCGTGTGGCCAGGTCGGCCAGAGCCCGAAGAGGCG
CCAGGGGGCGTCCAGCTGCA

Product: lysine decarboxylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 495; Mature: 494

Protein sequence:

>495_residues
MSEEQQRAPYLEQWLAYVDECVIPFTTPGHKQGRGAPPEFVAAFGERALALDIPHDGGTFDAHLEHDPLVAAERLAAALW
GARDAVFLVNGSTTGNLAALLTLGRPGQPIVVTRAMHKSLLAGLVLSGARPVYVVPAVHPESGILLDLPPESVAQALAAW
PDATAVALVSPTYTGVTSDTAELAALCHAHGVPLFVDEAWGPHLPFHPALPAAAIPSGADLAVTSLHKLAGSLTQTALLL
MAGNLVDQAQLRAATAMVQTTSPAAFLYASLDAARRRLALEGEQLLARTLELAEHARRELAAIPGLEVVGPEIVAGRPGA
GFDRTRLVVDVQGFGLTGLEVKRILRRDFRIAAEMADLVSVVFLITIGDTPETIAALVAAFRALAADRTRPDCAAGRRAV
RALLRSTGPIVAGAPQAMTPREAFFAPAERVPLADAVGRVAAEPVTPYPPGIPVLAPGEVVRPEVVEFLQAGRAAGMRFN
GASDPTLATLRVVRA

Sequences:

>Translated_495_residues
MSEEQQRAPYLEQWLAYVDECVIPFTTPGHKQGRGAPPEFVAAFGERALALDIPHDGGTFDAHLEHDPLVAAERLAAALW
GARDAVFLVNGSTTGNLAALLTLGRPGQPIVVTRAMHKSLLAGLVLSGARPVYVVPAVHPESGILLDLPPESVAQALAAW
PDATAVALVSPTYTGVTSDTAELAALCHAHGVPLFVDEAWGPHLPFHPALPAAAIPSGADLAVTSLHKLAGSLTQTALLL
MAGNLVDQAQLRAATAMVQTTSPAAFLYASLDAARRRLALEGEQLLARTLELAEHARRELAAIPGLEVVGPEIVAGRPGA
GFDRTRLVVDVQGFGLTGLEVKRILRRDFRIAAEMADLVSVVFLITIGDTPETIAALVAAFRALAADRTRPDCAAGRRAV
RALLRSTGPIVAGAPQAMTPREAFFAPAERVPLADAVGRVAAEPVTPYPPGIPVLAPGEVVRPEVVEFLQAGRAAGMRFN
GASDPTLATLRVVRA
>Mature_494_residues
SEEQQRAPYLEQWLAYVDECVIPFTTPGHKQGRGAPPEFVAAFGERALALDIPHDGGTFDAHLEHDPLVAAERLAAALWG
ARDAVFLVNGSTTGNLAALLTLGRPGQPIVVTRAMHKSLLAGLVLSGARPVYVVPAVHPESGILLDLPPESVAQALAAWP
DATAVALVSPTYTGVTSDTAELAALCHAHGVPLFVDEAWGPHLPFHPALPAAAIPSGADLAVTSLHKLAGSLTQTALLLM
AGNLVDQAQLRAATAMVQTTSPAAFLYASLDAARRRLALEGEQLLARTLELAEHARRELAAIPGLEVVGPEIVAGRPGAG
FDRTRLVVDVQGFGLTGLEVKRILRRDFRIAAEMADLVSVVFLITIGDTPETIAALVAAFRALAADRTRPDCAAGRRAVR
ALLRSTGPIVAGAPQAMTPREAFFAPAERVPLADAVGRVAAEPVTPYPPGIPVLAPGEVVRPEVVEFLQAGRAAGMRFNG
ASDPTLATLRVVRA

Specific function: Catalyzes the formation of agmatine from arginine [H]

COG id: COG1982

COG function: function code E; Arginine/lysine/ornithine decarboxylases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Orn/Lys/Arg decarboxylase class-I family [H]

Homologues:

Organism=Escherichia coli, GI1790573, Length=558, Percent_Identity=23.6559139784946, Blast_Score=108, Evalue=1e-24,
Organism=Escherichia coli, GI1786909, Length=585, Percent_Identity=24.4444444444444, Blast_Score=99, Evalue=5e-22,
Organism=Escherichia coli, GI1786384, Length=316, Percent_Identity=27.8481012658228, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI221142684, Length=311, Percent_Identity=25.08038585209, Blast_Score=79, Evalue=9e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000310
- InterPro:   IPR008286
- InterPro:   IPR015424
- InterPro:   IPR015421 [H]

Pfam domain/function: PF01276 OKR_DC_1; PF03711 OKR_DC_1_C [H]

EC number: =4.1.1.19 [H]

Molecular weight: Translated: 51884; Mature: 51753

Theoretical pI: Translated: 6.10; Mature: 6.10

Prosite motif: PS00703 OKR_DC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEEQQRAPYLEQWLAYVDECVIPFTTPGHKQGRGAPPEFVAAFGERALALDIPHDGGTF
CCCHHHCCCHHHHHHHHHHHCEECCCCCCCCCCCCCCHHHHHHHCCCEEEEECCCCCCCE
DAHLEHDPLVAAERLAAALWGARDAVFLVNGSTTGNLAALLTLGRPGQPIVVTRAMHKSL
ECCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCEEEEEEECCCCCCEEEHHHHHHHH
LAGLVLSGARPVYVVPAVHPESGILLDLPPESVAQALAAWPDATAVALVSPTYTGVTSDT
HHHHHHCCCCCEEEEEEECCCCCEEEECCHHHHHHHHHHCCCCCEEEEECCCCCCCCCCH
AELAALCHAHGVPLFVDEAWGPHLPFHPALPAAAIPSGADLAVTSLHKLAGSLTQTALLL
HHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
MAGNLVDQAQLRAATAMVQTTSPAAFLYASLDAARRRLALEGEQLLARTLELAEHARREL
HHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
AAIPGLEVVGPEIVAGRPGAGFDRTRLVVDVQGFGLTGLEVKRILRRDFRIAAEMADLVS
HHCCCCHHCCCCEEECCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHH
VVFLITIGDTPETIAALVAAFRALAADRTRPDCAAGRRAVRALLRSTGPIVAGAPQAMTP
HHHHEEECCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCEEECCCCCCCC
REAFFAPAERVPLADAVGRVAAEPVTPYPPGIPVLAPGEVVRPEVVEFLQAGRAAGMRFN
HHHHCCCHHCCCHHHHHHHHHCCCCCCCCCCCCEECCCCCCCHHHHHHHHCCHHCCEEEC
GASDPTLATLRVVRA
CCCCCHHHHHEEECC
>Mature Secondary Structure 
SEEQQRAPYLEQWLAYVDECVIPFTTPGHKQGRGAPPEFVAAFGERALALDIPHDGGTF
CCHHHCCCHHHHHHHHHHHCEECCCCCCCCCCCCCCHHHHHHHCCCEEEEECCCCCCCE
DAHLEHDPLVAAERLAAALWGARDAVFLVNGSTTGNLAALLTLGRPGQPIVVTRAMHKSL
ECCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCEEEEEEECCCCCCEEEHHHHHHHH
LAGLVLSGARPVYVVPAVHPESGILLDLPPESVAQALAAWPDATAVALVSPTYTGVTSDT
HHHHHHCCCCCEEEEEEECCCCCEEEECCHHHHHHHHHHCCCCCEEEEECCCCCCCCCCH
AELAALCHAHGVPLFVDEAWGPHLPFHPALPAAAIPSGADLAVTSLHKLAGSLTQTALLL
HHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
MAGNLVDQAQLRAATAMVQTTSPAAFLYASLDAARRRLALEGEQLLARTLELAEHARREL
HHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
AAIPGLEVVGPEIVAGRPGAGFDRTRLVVDVQGFGLTGLEVKRILRRDFRIAAEMADLVS
HHCCCCHHCCCCEEECCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHH
VVFLITIGDTPETIAALVAAFRALAADRTRPDCAAGRRAVRALLRSTGPIVAGAPQAMTP
HHHHEEECCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCEEECCCCCCCC
REAFFAPAERVPLADAVGRVAAEPVTPYPPGIPVLAPGEVVRPEVVEFLQAGRAAGMRFN
HHHHCCCHHCCCHHHHHHHHHCCCCCCCCCCCCEECCCCCCCHHHHHHHHCCHHCCEEEC
GASDPTLATLRVVRA
CCCCCHHHHHEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]