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The map label for this gene is glnA [H]

Identifier: 221633533

GI number: 221633533

Start: 1536527

End: 1537996

Strand: Reverse

Name: glnA [H]

Synonym: trd_1557

Alternate gene names: 221633533

Gene position: 1537996-1536527 (Counterclockwise)

Preceding gene: 221633534

Following gene: 221633530

Centisome position: 76.78

GC content: 61.29

Gene sequence:

>1470_bases
ATGCAGGGCCACGAGGGCCACGACGCGGCTACCCGCTGGGCGGGTGTGCAGTGGCGTCGCCGGCGGATCGGCAGTGATGG
TCGAGTCCGTGAAGGAGGGTTTGCGTTGGTCGTCGATACGAGCGTGATCGGTCGTCGTGCTGCTGCGCCGAGCCCGGAGG
AGGTGCTCCGGCGCGCAGAAGAGCTCAAGATCGAGTTCGTCAGTCTGCAATTCACCGACATCATGGGGATCGTCAAGAAC
GTCCAGATTCCCATCGATGTGTTTCCCCACGTTATCGAGCAGGGCCAGTGGTTCGATGGTTCGTCGATCGAGGGGTTCGC
GCGCATCGCGGAAAGCGACATGTACCTCATGCCCGACCTCTCGACCTTCTCCCCTATTCCCTGGGATCCCCAGACCGCTC
GCGTCATTTGCTGGGTCTACAATCCGAATGGTGAACTGTTTCCCGGTGACCCGCGGGTCGTCCTGCTGCGTCAGCTCGAG
CGGGCAGCCAAGCTCGGCCTCGTCTACAATACCGGTCCCGAGCTGGAGTTCTTTCTGTTCCGCAAGGAGAACGGCAAGAT
CATGCCACTCCCGCATGACCAGGGGAGCTACTTCGACTTGACCACCGACCTGGCCGCCGAGGTGCGCAAGGACATGATCC
GGGCCTTGCAAGCGTTCGGCATCAAGGTCGAGGCTGGTCACCACGAGGTCGCCATCGGTCAGCACGAAATCGACTTCGAG
TATTCCGATGCGCTGACGACAGCCGACAACGCGATCACCTTCAAGTACACCTTGAAAGCGATCGCTCAACAGCATGATCT
GCATGCCACCTTCATGCCCAAGCCGATCGCCGGGATCAATGGCAGCGGCATGCACACGCACCAGAGCCTGGCCTCGCTCG
AGACCGGTGCTAATCTCTTCGTCGATGTCGAGGACCCCTACGGTCTCTCCGATCTCGCCAAGCACTTCATCGCGGGGCAG
CTCGCGCACGCGCGAGGGATGTGCGCGGTTCTGGCACCGCTCGTCAACAGCTACAAGCGACTGGTTCCCGGATACGAGGC
GCCGGTATACATCAGCTGGGCACGACAGAACCGCTCAGCGCTCATCCGCGTCCCTGCCGTGCGGCATGGTCGCCTGCAAG
CGACGCGTATCGAATTGCGTTGTCCTGATCCCTCGGCGAACCCCTATCTCGCCTATGCTGTCATGTTGGCAGCCGGGCTG
GATGGGATCGAGCGCAAGCTGCCACTTCCCGAGCCGGTGGAGGAGAATGTCTACCACTTCACCGACGAGGACCTCAAGCG
ACGCAACATCCAAACGCTACCGGCGACCCTCGGTGAAGCGATGGCCGAACTCGAAAAGGACGAGGTGATCCGCGAGGCTC
TCGGCGAACATGTCTTCGAGCGATTGCTCGAGGCGCAGAAGCGCGACTGGGATGCTTTCCGGCAGTATGTCACCCAGTGG
GAACTCGATCGTTACCTCGAGATCTATTGA

Upstream 100 bases:

>100_bases
ATCCCTATGAATTCTACCTGTACTTTGATATCTAGGGACGGGAACCGATGGTGGGTGGGGATGGGAGGTGCTCTGGTGGG
GCCGTGAAAGGAGTACACTG

Downstream 100 bases:

>100_bases
CGGAAAACTCGAGCGACGCCCCGGCTTGCCGGGGCGTCGCTCTTCATCCACACGCGCGACGTGCTCCTACCGCTGATCTT
CACCGTCCAGTGCGCGCGAC

Product: glutamine synthetase, type I

Products: NA

Alternate protein names: GS; Glutamate--ammonia ligase [H]

Number of amino acids: Translated: 489; Mature: 489

Protein sequence:

>489_residues
MQGHEGHDAATRWAGVQWRRRRIGSDGRVREGGFALVVDTSVIGRRAAAPSPEEVLRRAEELKIEFVSLQFTDIMGIVKN
VQIPIDVFPHVIEQGQWFDGSSIEGFARIAESDMYLMPDLSTFSPIPWDPQTARVICWVYNPNGELFPGDPRVVLLRQLE
RAAKLGLVYNTGPELEFFLFRKENGKIMPLPHDQGSYFDLTTDLAAEVRKDMIRALQAFGIKVEAGHHEVAIGQHEIDFE
YSDALTTADNAITFKYTLKAIAQQHDLHATFMPKPIAGINGSGMHTHQSLASLETGANLFVDVEDPYGLSDLAKHFIAGQ
LAHARGMCAVLAPLVNSYKRLVPGYEAPVYISWARQNRSALIRVPAVRHGRLQATRIELRCPDPSANPYLAYAVMLAAGL
DGIERKLPLPEPVEENVYHFTDEDLKRRNIQTLPATLGEAMAELEKDEVIREALGEHVFERLLEAQKRDWDAFRQYVTQW
ELDRYLEIY

Sequences:

>Translated_489_residues
MQGHEGHDAATRWAGVQWRRRRIGSDGRVREGGFALVVDTSVIGRRAAAPSPEEVLRRAEELKIEFVSLQFTDIMGIVKN
VQIPIDVFPHVIEQGQWFDGSSIEGFARIAESDMYLMPDLSTFSPIPWDPQTARVICWVYNPNGELFPGDPRVVLLRQLE
RAAKLGLVYNTGPELEFFLFRKENGKIMPLPHDQGSYFDLTTDLAAEVRKDMIRALQAFGIKVEAGHHEVAIGQHEIDFE
YSDALTTADNAITFKYTLKAIAQQHDLHATFMPKPIAGINGSGMHTHQSLASLETGANLFVDVEDPYGLSDLAKHFIAGQ
LAHARGMCAVLAPLVNSYKRLVPGYEAPVYISWARQNRSALIRVPAVRHGRLQATRIELRCPDPSANPYLAYAVMLAAGL
DGIERKLPLPEPVEENVYHFTDEDLKRRNIQTLPATLGEAMAELEKDEVIREALGEHVFERLLEAQKRDWDAFRQYVTQW
ELDRYLEIY
>Mature_489_residues
MQGHEGHDAATRWAGVQWRRRRIGSDGRVREGGFALVVDTSVIGRRAAAPSPEEVLRRAEELKIEFVSLQFTDIMGIVKN
VQIPIDVFPHVIEQGQWFDGSSIEGFARIAESDMYLMPDLSTFSPIPWDPQTARVICWVYNPNGELFPGDPRVVLLRQLE
RAAKLGLVYNTGPELEFFLFRKENGKIMPLPHDQGSYFDLTTDLAAEVRKDMIRALQAFGIKVEAGHHEVAIGQHEIDFE
YSDALTTADNAITFKYTLKAIAQQHDLHATFMPKPIAGINGSGMHTHQSLASLETGANLFVDVEDPYGLSDLAKHFIAGQ
LAHARGMCAVLAPLVNSYKRLVPGYEAPVYISWARQNRSALIRVPAVRHGRLQATRIELRCPDPSANPYLAYAVMLAAGL
DGIERKLPLPEPVEENVYHFTDEDLKRRNIQTLPATLGEAMAELEKDEVIREALGEHVFERLLEAQKRDWDAFRQYVTQW
ELDRYLEIY

Specific function: Unknown

COG id: COG0174

COG function: function code E; Glutamine synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutamine synthetase family [H]

Homologues:

Organism=Homo sapiens, GI221307485, Length=431, Percent_Identity=27.8422273781903, Blast_Score=153, Evalue=4e-37,
Organism=Escherichia coli, GI1790301, Length=441, Percent_Identity=39.2290249433107, Blast_Score=259, Evalue=3e-70,
Organism=Escherichia coli, GI87081870, Length=470, Percent_Identity=28.936170212766, Blast_Score=157, Evalue=1e-39,

Paralogues:

None

Copy number: 420 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 15324 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 8,000 Molecules/Cell In: Glucose minimal medi

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008147
- InterPro:   IPR014746
- InterPro:   IPR008146
- InterPro:   IPR004809 [H]

Pfam domain/function: PF00120 Gln-synt_C; PF03951 Gln-synt_N [H]

EC number: =6.3.1.2 [H]

Molecular weight: Translated: 55138; Mature: 55138

Theoretical pI: Translated: 5.60; Mature: 5.60

Prosite motif: PS00180 GLNA_1 ; PS00181 GLNA_ATP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQGHEGHDAATRWAGVQWRRRRIGSDGRVREGGFALVVDTSVIGRRAAAPSPEEVLRRAE
CCCCCCCCHHHHHHCHHHHHHHCCCCCCEECCCEEEEEECHHHCCCCCCCCHHHHHHHHH
ELKIEFVSLQFTDIMGIVKNVQIPIDVFPHVIEQGQWFDGSSIEGFARIAESDMYLMPDL
HCEEEEEEEEHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHCCCEEEECCC
STFSPIPWDPQTARVICWVYNPNGELFPGDPRVVLLRQLERAAKLGLVYNTGPELEFFLF
CCCCCCCCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCEEECCCCCEEEEEE
RKENGKIMPLPHDQGSYFDLTTDLAAEVRKDMIRALQAFGIKVEAGHHEVAIGQHEIDFE
ECCCCCEECCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHCEEEECCCCEEEECCEECCCC
YSDALTTADNAITFKYTLKAIAQQHDLHATFMPKPIAGINGSGMHTHQSLASLETGANLF
CCCCEECCCCEEEEHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCHHHHHHHHHCCCEEE
VDVEDPYGLSDLAKHFIAGQLAHARGMCAVLAPLVNSYKRLVPGYEAPVYISWARQNRSA
EECCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCE
LIRVPAVRHGRLQATRIELRCPDPSANPYLAYAVMLAAGLDGIERKLPLPEPVEENVYHF
EEEECCCCCCCEEEEEEEEECCCCCCCCHHHHHHHHHHCCCHHHHCCCCCCCHHCCCEEC
TDEDLKRRNIQTLPATLGEAMAELEKDEVIREALGEHVFERLLEAQKRDWDAFRQYVTQW
CCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
ELDRYLEIY
HHHHHEECC
>Mature Secondary Structure
MQGHEGHDAATRWAGVQWRRRRIGSDGRVREGGFALVVDTSVIGRRAAAPSPEEVLRRAE
CCCCCCCCHHHHHHCHHHHHHHCCCCCCEECCCEEEEEECHHHCCCCCCCCHHHHHHHHH
ELKIEFVSLQFTDIMGIVKNVQIPIDVFPHVIEQGQWFDGSSIEGFARIAESDMYLMPDL
HCEEEEEEEEHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHCCCEEEECCC
STFSPIPWDPQTARVICWVYNPNGELFPGDPRVVLLRQLERAAKLGLVYNTGPELEFFLF
CCCCCCCCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCEEECCCCCEEEEEE
RKENGKIMPLPHDQGSYFDLTTDLAAEVRKDMIRALQAFGIKVEAGHHEVAIGQHEIDFE
ECCCCCEECCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHCEEEECCCCEEEECCEECCCC
YSDALTTADNAITFKYTLKAIAQQHDLHATFMPKPIAGINGSGMHTHQSLASLETGANLF
CCCCEECCCCEEEEHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCHHHHHHHHHCCCEEE
VDVEDPYGLSDLAKHFIAGQLAHARGMCAVLAPLVNSYKRLVPGYEAPVYISWARQNRSA
EECCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCE
LIRVPAVRHGRLQATRIELRCPDPSANPYLAYAVMLAAGLDGIERKLPLPEPVEENVYHF
EEEECCCCCCCEEEEEEEEECCCCCCCCHHHHHHHHHHCCCHHHHCCCCCCCHHCCCEEC
TDEDLKRRNIQTLPATLGEAMAELEKDEVIREALGEHVFERLLEAQKRDWDAFRQYVTQW
CCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
ELDRYLEIY
HHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7916055 [H]