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The map label for this gene is yfiK [H]

Identifier: 221633529

GI number: 221633529

Start: 1533081

End: 1533854

Strand: Reverse

Name: yfiK [H]

Synonym: trd_1551

Alternate gene names: 221633529

Gene position: 1533854-1533081 (Counterclockwise)

Preceding gene: 221633530

Following gene: 221633528

Centisome position: 76.58

GC content: 61.89

Gene sequence:

>774_bases
GTGCCGAAGCGGTGGGAGGAAGGTTGCGGGTCACCTCGCTTCCGGGCCAGGGAACGACGGTCGAGGCGGTGCTTCCGGTC
GGCATCGTCCTGGCTGAAACGACTGGAGGACGAGATGCGTCTCTTGATCGTCGATGACCATGCGCTCTTTCGCGATGGCC
TGCGCAGCCTCCTGGAAGCACGGGGTGTCGAGGTCGTCGGCGAGGCGGCGAATGGACGCGAGGCGGTGGAACTCGCGCGC
CAGCTGAAACCGGATATCGTGCTTATGGATCTCACGATGCCAGAAGTCGATGGCTTGACGGCGACACGCATTCTCGTGAC
GGAACTCCCGGAAGTGAAAGTCGTCGTGCTCACCGCCTCGGACGACGAGGCAGATCTCTTCGAGTCCATCAAGTCGGGCG
CGTACGGGTACTTGCTCAAGAACCTGGAGGCTGACGAGTTCTTTCGCGCGCTCGAAGCAGTCCAGTCGGGTCTGCCGGTC
TTCACTCCCCATCTCGCGCGACGGGTTTTGCAAGAGTTCGGCCGGGAGGGAGTGCACCGCCCCGAAGGACCGGCTTTGAC
AGAGCGCGAACGCGAACTCTTGGAACTGCTCGTGCAAGGTGTGACCTCGAACCGAGAACTAGCCCAGCGGCTCTTCATCA
GCGAGAACACGGTCAAGTATCACCTGCGCAACATCATGACCAAACTTCACCTGGAAAATCGGGCACAGGTGATCGCCTAC
GCTCTCCGGACTGGCCTTGTCCGCACCCGGCCCGACGAGCCACCACGTTCCTAA

Upstream 100 bases:

>100_bases
ACGGTGTGCGTTCGTGTGGCGGACAATGGGATCGGTTTCGATCCAGGAGCGCTGGAGCGCGGACAGTTCCCACGTTTTGG
GCTCGCGACGATGCGCGAGC

Downstream 100 bases:

>100_bases
TCGGCGTCGATGTCCGAGTCCATCATGTTGTGCGCTGTGCCTCGCCTGCGACTCCTGAACCTGTCCGCCCCAAAGCGACG
AAAGTTTCTCGGTCGAGGGC

Product: putative two-component system response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 257; Mature: 256

Protein sequence:

>257_residues
MPKRWEEGCGSPRFRARERRSRRCFRSASSWLKRLEDEMRLLIVDDHALFRDGLRSLLEARGVEVVGEAANGREAVELAR
QLKPDIVLMDLTMPEVDGLTATRILVTELPEVKVVVLTASDDEADLFESIKSGAYGYLLKNLEADEFFRALEAVQSGLPV
FTPHLARRVLQEFGREGVHRPEGPALTERERELLELLVQGVTSNRELAQRLFISENTVKYHLRNIMTKLHLENRAQVIAY
ALRTGLVRTRPDEPPRS

Sequences:

>Translated_257_residues
MPKRWEEGCGSPRFRARERRSRRCFRSASSWLKRLEDEMRLLIVDDHALFRDGLRSLLEARGVEVVGEAANGREAVELAR
QLKPDIVLMDLTMPEVDGLTATRILVTELPEVKVVVLTASDDEADLFESIKSGAYGYLLKNLEADEFFRALEAVQSGLPV
FTPHLARRVLQEFGREGVHRPEGPALTERERELLELLVQGVTSNRELAQRLFISENTVKYHLRNIMTKLHLENRAQVIAY
ALRTGLVRTRPDEPPRS
>Mature_256_residues
PKRWEEGCGSPRFRARERRSRRCFRSASSWLKRLEDEMRLLIVDDHALFRDGLRSLLEARGVEVVGEAANGREAVELARQ
LKPDIVLMDLTMPEVDGLTATRILVTELPEVKVVVLTASDDEADLFESIKSGAYGYLLKNLEADEFFRALEAVQSGLPVF
TPHLARRVLQEFGREGVHRPEGPALTERERELLELLVQGVTSNRELAQRLFISENTVKYHLRNIMTKLHLENRAQVIAYA
LRTGLVRTRPDEPPRS

Specific function: Member of the two-component regulatory system yfiJ/yfiK [H]

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788521, Length=196, Percent_Identity=39.7959183673469, Blast_Score=126, Evalue=1e-30,
Organism=Escherichia coli, GI1788222, Length=212, Percent_Identity=32.5471698113208, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1787473, Length=187, Percent_Identity=38.5026737967914, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1790102, Length=193, Percent_Identity=31.6062176165803, Blast_Score=87, Evalue=8e-19,
Organism=Escherichia coli, GI1788712, Length=208, Percent_Identity=26.4423076923077, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1786747, Length=202, Percent_Identity=26.7326732673267, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1788546, Length=208, Percent_Identity=28.3653846153846, Blast_Score=74, Evalue=7e-15,
Organism=Escherichia coli, GI1788550, Length=108, Percent_Identity=35.1851851851852, Blast_Score=68, Evalue=5e-13,
Organism=Escherichia coli, GI1787277, Length=93, Percent_Identity=40.8602150537634, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI87082052, Length=106, Percent_Identity=35.8490566037736, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1790437, Length=116, Percent_Identity=33.6206896551724, Blast_Score=61, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6322044, Length=114, Percent_Identity=28.9473684210526, Blast_Score=62, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 29325; Mature: 29194

Theoretical pI: Translated: 7.06; Mature: 7.06

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKRWEEGCGSPRFRARERRSRRCFRSASSWLKRLEDEMRLLIVDDHALFRDGLRSLLEA
CCCCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCHHHHHHHHHHHHHH
RGVEVVGEAANGREAVELARQLKPDIVLMDLTMPEVDGLTATRILVTELPEVKVVVLTAS
CCCCEECCCCCCHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHCCCCEEEEEEECC
DDEADLFESIKSGAYGYLLKNLEADEFFRALEAVQSGLPVFTPHLARRVLQEFGREGVHR
CCHHHHHHHHHCCHHHHHHHCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCC
PEGPALTERERELLELLVQGVTSNRELAQRLFISENTVKYHLRNIMTKLHLENRAQVIAY
CCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
ALRTGLVRTRPDEPPRS
HHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
PKRWEEGCGSPRFRARERRSRRCFRSASSWLKRLEDEMRLLIVDDHALFRDGLRSLLEA
CCCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCHHHHHHHHHHHHHH
RGVEVVGEAANGREAVELARQLKPDIVLMDLTMPEVDGLTATRILVTELPEVKVVVLTAS
CCCCEECCCCCCHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHCCCCEEEEEEECC
DDEADLFESIKSGAYGYLLKNLEADEFFRALEAVQSGLPVFTPHLARRVLQEFGREGVHR
CCHHHHHHHHHCCHHHHHHHCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCC
PEGPALTERERELLELLVQGVTSNRELAQRLFISENTVKYHLRNIMTKLHLENRAQVIAY
CCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
ALRTGLVRTRPDEPPRS
HHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8973323; 9384377 [H]