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The map label for this gene is soxA [H]

Identifier: 221633429

GI number: 221633429

Start: 1440105

End: 1441520

Strand: Reverse

Name: soxA [H]

Synonym: trd_1450

Alternate gene names: 221633429

Gene position: 1441520-1440105 (Counterclockwise)

Preceding gene: 221633432

Following gene: 221633424

Centisome position: 71.97

GC content: 67.51

Gene sequence:

>1416_bases
GTGCTGTTGACCGTTCCTGAAGCGCACACTGAACGATGCAGCCAGCATCCATCGTTGTCGACTGGCTACGCCGGGCGCGT
GCGTTCGTTTCCGCTCGTCAGCTGCGCTGCTGTACTCCAGCTGATTCGTGTCCCGCGCGGAGGCACGAACAGCCATCTCG
TCCAGGCCGCGGAGCGTGCGCACTTGACCGGCGCGGAGCGAACTGGTTGGATGACCACGACCGGGGAGGAAGGCATGGCG
GCGACTGCTGAGGTGGTGATCGTCGGAGCAGGAATCGTCGGCGCGAGTGTCGCCTACTGGCTGACCGAGTTCGGGATGCG
GGATGTGCTCGTCGTCGAGCGCCGCGTTCCCGCTTCTGGGGCAACCGGGAAATCCGGGGCACTGGTGCGGTTGCACTATC
CCAACCCGCACGAAACCCAGCTCGCACTCGAAAGTCTCCGTTTCTTCCAGGAATGGGAGAGCCGGGTCGGGACATCCTCG
CCCTTCGTCCGCACTGGCTTCCTGCAAGTCGTCGCACCGGATGACGAGGCAAAGCTGCGCCAGAACGTGGCGCTGCACCA
GGCGCTGGGTGCTCCCGTGACGCTGCTCGATCGCGCAGCGGTCGCCGAACTCGAGCCGTGGCGCGAGTTGGGTGAGTTGA
CCGTCGCGGCCTACGAGCCGGAGAGCGGGTATGCCGACCCGATCGCGGCGACACTGGGGTTGCTCGCGCGCGCGGAGCAG
CGTGGTGCCACGTTCTGGCCGGGGACGACGGTCACCGAGGTGCTGCTCGCCGGGGATCGAGTCGCTGGCGTCGAGACGAC
GCGCGGACCGATCGCTGCTCCAGTGGTGGTTCTCGCACCGGGCCCATGGGCCAACCGGCTGCTCGCCCCGCTCGGTCTCG
ACTATCAGTTGCTACCGCGTCGGGTGCAGGTTGTCGTGTTCCGTTGGCCGCTCGAGCCGGCACCCGCGCATTGTTGCGGG
ATCGATACGGCTGTTGGCTTGTGGTACCGGCCAGAGGGCAAGACCGCGACGCTGGTCGGCTTGGAAGCGGGTGTTCAGCC
GGCTGACCCGGACCACTATCCGGAGACGGCCGATCCGAGCTTCGTCGCGCCCGCCAGGGCAGCGATCGCGCGTCGCTACC
CCGCGCTGGCTGAGGGGATCGTGCGCGGAGGCTGGGCGGGTATCGTCATGCAGAGTCCGGACGGGCGGCCACTCTTCGGG
CCGATTCCGGAGTATTCTGGCTTGTTCGCGTTTCTCGGTGATTCGGGCACGTCGTTCAAGACCGCTCCCGCGATCGGGCG
CGCGTTGGCGGAGTGGATCGTCTCCGGACGCTCGTCGCGCGATCTGACGCCTTTTCGAGTGGCGCGACTGGCGGAGGGGC
GCCCCTGGATCGATCCGACCGATTATGCCCGGCCTGGTCGGACGGTCTCCCGCTGA

Upstream 100 bases:

>100_bases
TTTTCCCCTCTCGGACACTCTTGTCGCCGCAGCAAGCACCACGACTCGCGCTTCTGCTTCGCGGAGCGGGACCGACCGGT
GAACAGGAGCACCACCGAGA

Downstream 100 bases:

>100_bases
CGGTGGTTCCACCAGGCGTAGAGGCCGCGCTTGGCCAGTTCGACCAGCGCGAGGTAGCTGGTCACCGCGACGGCGAGGAA
GAGGAGATAGCTCGGTGGCA

Product: putative FAD dependent oxidoreductase

Products: NA

Alternate protein names: MSOX [H]

Number of amino acids: Translated: 471; Mature: 471

Protein sequence:

>471_residues
MLLTVPEAHTERCSQHPSLSTGYAGRVRSFPLVSCAAVLQLIRVPRGGTNSHLVQAAERAHLTGAERTGWMTTTGEEGMA
ATAEVVIVGAGIVGASVAYWLTEFGMRDVLVVERRVPASGATGKSGALVRLHYPNPHETQLALESLRFFQEWESRVGTSS
PFVRTGFLQVVAPDDEAKLRQNVALHQALGAPVTLLDRAAVAELEPWRELGELTVAAYEPESGYADPIAATLGLLARAEQ
RGATFWPGTTVTEVLLAGDRVAGVETTRGPIAAPVVVLAPGPWANRLLAPLGLDYQLLPRRVQVVVFRWPLEPAPAHCCG
IDTAVGLWYRPEGKTATLVGLEAGVQPADPDHYPETADPSFVAPARAAIARRYPALAEGIVRGGWAGIVMQSPDGRPLFG
PIPEYSGLFAFLGDSGTSFKTAPAIGRALAEWIVSGRSSRDLTPFRVARLAEGRPWIDPTDYARPGRTVSR

Sequences:

>Translated_471_residues
MLLTVPEAHTERCSQHPSLSTGYAGRVRSFPLVSCAAVLQLIRVPRGGTNSHLVQAAERAHLTGAERTGWMTTTGEEGMA
ATAEVVIVGAGIVGASVAYWLTEFGMRDVLVVERRVPASGATGKSGALVRLHYPNPHETQLALESLRFFQEWESRVGTSS
PFVRTGFLQVVAPDDEAKLRQNVALHQALGAPVTLLDRAAVAELEPWRELGELTVAAYEPESGYADPIAATLGLLARAEQ
RGATFWPGTTVTEVLLAGDRVAGVETTRGPIAAPVVVLAPGPWANRLLAPLGLDYQLLPRRVQVVVFRWPLEPAPAHCCG
IDTAVGLWYRPEGKTATLVGLEAGVQPADPDHYPETADPSFVAPARAAIARRYPALAEGIVRGGWAGIVMQSPDGRPLFG
PIPEYSGLFAFLGDSGTSFKTAPAIGRALAEWIVSGRSSRDLTPFRVARLAEGRPWIDPTDYARPGRTVSR
>Mature_471_residues
MLLTVPEAHTERCSQHPSLSTGYAGRVRSFPLVSCAAVLQLIRVPRGGTNSHLVQAAERAHLTGAERTGWMTTTGEEGMA
ATAEVVIVGAGIVGASVAYWLTEFGMRDVLVVERRVPASGATGKSGALVRLHYPNPHETQLALESLRFFQEWESRVGTSS
PFVRTGFLQVVAPDDEAKLRQNVALHQALGAPVTLLDRAAVAELEPWRELGELTVAAYEPESGYADPIAATLGLLARAEQ
RGATFWPGTTVTEVLLAGDRVAGVETTRGPIAAPVVVLAPGPWANRLLAPLGLDYQLLPRRVQVVVFRWPLEPAPAHCCG
IDTAVGLWYRPEGKTATLVGLEAGVQPADPDHYPETADPSFVAPARAAIARRYPALAEGIVRGGWAGIVMQSPDGRPLFG
PIPEYSGLFAFLGDSGTSFKTAPAIGRALAEWIVSGRSSRDLTPFRVARLAEGRPWIDPTDYARPGRTVSR

Specific function: Catalyzes the oxidative demethylation of sarcosine. Can also oxidize other secondary amino acids such as N-methyl-L- alanine [H]

COG id: COG0665

COG function: function code E; Glycine/D-amino acid oxidases (deaminating)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MSOX/MTOX family. MSOX subfamily [H]

Homologues:

Organism=Homo sapiens, GI197927446, Length=391, Percent_Identity=27.1099744245524, Blast_Score=110, Evalue=4e-24,
Organism=Homo sapiens, GI21361378, Length=391, Percent_Identity=27.1099744245524, Blast_Score=110, Evalue=4e-24,
Organism=Homo sapiens, GI8923708, Length=402, Percent_Identity=26.865671641791, Blast_Score=99, Evalue=9e-21,
Organism=Homo sapiens, GI24797151, Length=379, Percent_Identity=24.5382585751979, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI194306651, Length=397, Percent_Identity=25.1889168765743, Blast_Score=96, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI71994045, Length=377, Percent_Identity=24.6684350132626, Blast_Score=65, Evalue=6e-11,
Organism=Drosophila melanogaster, GI20130091, Length=416, Percent_Identity=25.2403846153846, Blast_Score=89, Evalue=5e-18,
Organism=Drosophila melanogaster, GI20129729, Length=407, Percent_Identity=26.5356265356265, Blast_Score=84, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR006281 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.5.3.1 [H]

Molecular weight: Translated: 50403; Mature: 50403

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLTVPEAHTERCSQHPSLSTGYAGRVRSFPLVSCAAVLQLIRVPRGGTNSHLVQAAERA
CEEECCCHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
HLTGAERTGWMTTTGEEGMAATAEVVIVGAGIVGASVAYWLTEFGMRDVLVVERRVPASG
HCCCCCCCCCEEECCCCCCCEEEEEEEEECCHHHHHHHHHHHHHCCCCEEEEEECCCCCC
ATGKSGALVRLHYPNPHETQLALESLRFFQEWESRVGTSSPFVRTGFLQVVAPDDEAKLR
CCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEECEEEEECCCHHHHHH
QNVALHQALGAPVTLLDRAAVAELEPWRELGELTVAAYEPESGYADPIAATLGLLARAEQ
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCHHHHHHHHHHHHHH
RGATFWPGTTVTEVLLAGDRVAGVETTRGPIAAPVVVLAPGPWANRLLAPLGLDYQLLPR
CCCEECCCHHHHHHHHCCCCCCCCCCCCCCCCCCEEEECCCCCHHHHHHHCCCCHHHCCC
RVQVVVFRWPLEPAPAHCCGIDTAVGLWYRPEGKTATLVGLEAGVQPADPDHYPETADPS
EEEEEEEEECCCCCCCHHHCCHHHHCEEECCCCCEEEEEEEECCCCCCCCCCCCCCCCCC
FVAPARAAIARRYPALAEGIVRGGWAGIVMQSPDGRPLFGPIPEYSGLFAFLGDSGTSFK
CCCHHHHHHHHHCHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCCEEEEECCCCCCCC
TAPAIGRALAEWIVSGRSSRDLTPFRVARLAEGRPWIDPTDYARPGRTVSR
CHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MLLTVPEAHTERCSQHPSLSTGYAGRVRSFPLVSCAAVLQLIRVPRGGTNSHLVQAAERA
CEEECCCHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
HLTGAERTGWMTTTGEEGMAATAEVVIVGAGIVGASVAYWLTEFGMRDVLVVERRVPASG
HCCCCCCCCCEEECCCCCCCEEEEEEEEECCHHHHHHHHHHHHHCCCCEEEEEECCCCCC
ATGKSGALVRLHYPNPHETQLALESLRFFQEWESRVGTSSPFVRTGFLQVVAPDDEAKLR
CCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEECEEEEECCCHHHHHH
QNVALHQALGAPVTLLDRAAVAELEPWRELGELTVAAYEPESGYADPIAATLGLLARAEQ
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCHHHHHHHHHHHHHH
RGATFWPGTTVTEVLLAGDRVAGVETTRGPIAAPVVVLAPGPWANRLLAPLGLDYQLLPR
CCCEECCCHHHHHHHHCCCCCCCCCCCCCCCCCCEEEECCCCCHHHHHHHCCCCHHHCCC
RVQVVVFRWPLEPAPAHCCGIDTAVGLWYRPEGKTATLVGLEAGVQPADPDHYPETADPS
EEEEEEEEECCCCCCCHHHCCHHHHCEEECCCCCEEEEEEEECCCCCCCCCCCCCCCCCC
FVAPARAAIARRYPALAEGIVRGGWAGIVMQSPDGRPLFGPIPEYSGLFAFLGDSGTSFK
CCCHHHHHHHHHCHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCCEEEEECCCCCCCC
TAPAIGRALAEWIVSGRSSRDLTPFRVARLAEGRPWIDPTDYARPGRTVSR
CHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10220347; 10913293; 11087383; 10368302 [H]