Click here to switch to the map view.

The map label for this gene is 221633245

Identifier: 221633245

GI number: 221633245

Start: 1247963

End: 1249147

Strand: Reverse

Name: 221633245

Synonym: trd_1263

Alternate gene names: NA

Gene position: 1249147-1247963 (Counterclockwise)

Preceding gene: 221633247

Following gene: 221633244

Centisome position: 62.36

GC content: 65.57

Gene sequence:

>1185_bases
ATGAGCGCCGGCGAGCAGTTGGACGACTGGGGCTCATCGGTGGGACGAGCGATCTCGGTGGTGACAGTCCGCGGTGTCGC
GGTGCGGATCCACCCGACCATGCTCCTCCTCGTCCCCTGGGTGTTCTGGCACTGGGGGGGACGGAGCGCAGAACCGCTGG
AAGGGACGCTTTTCGGGCTCTTCTTGCTTCTGGCGGTTTTCGTGAGCGTGGCTGGACATGAACTCGCTCACGCTGTCGTC
GCGCATCGCTTCGGTCTCGCCGTGCGTGACGTCGTCCTTTTGCCGATCGGCGGTCTCACGCGTATCGAGCAGGGACCACT
ACCACCTCGCCGCGAGGCAGCGATCGCGTTGGCTGGTCCGGTGCTCAATCTCGGTATCGCACTCGCGCTCTTGCCAGTGG
TGAGCGTTGTCCTCGCTCTCTACGAGGTGACGTCGCTCGCGGATGTGGCTCGTCTCCTGACCGGGACGAGTGTCGGTAGC
TTGCTGATCCTGACCATGGCCAGCAACGTCCTGCTGGCATTGTTCAATCTGATCCCTGCTTTCCCGATGGACGGTGGTCG
GCTGTTGCGAGCATGGCTCTCGGCTCTGAGCGAGCGTGCGCGCGCGACACGGATCTCGTTGGTTACCGGGTATCTCGTGG
CCCTGGTGACGCTACCGCTCGGTCTGTGGCTACGAGAGCCGACTTTGCCGCTGGCTGGCCTTTTTCTGGCTGGTGCTGCC
TTGCTGGAGCAACGGACGCTCCAGCTGGAGCGTGTCCTGCAACGCCTTCCAGTCGGGCAGTTCGCCGTCTGGGATGGTGG
TGGAATCGACCCCGAGCAGCCGCTGTCCCATGCGCTGCAAGGGGGACCACGCGATGTCGCTGTCGTACGCGATGGAACGG
TCGTGGGGATGCTGTGGCGAGAAAACATCCTCCGGCTGGCGCATGTCGCGCATCTCATGCGCGTTGCTGATGCGATGGAC
CACGGCTTCGCTGCCGTGAGTCCGGAGACTTCCGTGTACGAAGCGCACCGCCGCATGCTGGCGAGCGGGCACCCCGCGGT
CCCCGTGGTCGACGCCGGGAACCGCTATCGCGGCATCTTCACCAGTGATCGGCTGGCGCACGTGTACCGCTACGTGCAAG
CGTCGCGTCGCCCGGCCGGGCGCTGGCTCACGGTCGTGCGGGCGCTCGGGTTCCTGGGGCGGTGA

Upstream 100 bases:

>100_bases
GAACACCGTGACGCATCGGTGGATGACCAGTACAATCCGGTCGGGGCATCGGTCTTCACAAGATGCCGGAGTGTGCCGAC
ATCATCGGGAGAAGGGCGCT

Downstream 100 bases:

>100_bases
CGGATCCTGAGCAGGAGGAACGGAGCGTGGCGGGCAGACGATCTTTCGACCCCTGGGCGGAGGGTTTTCCGTGGCGCGAA
CTCTTGGAACAGGCCTATGG

Product: peptidase, M50 family protein

Products: NA

Alternate protein names: Site-2-type intermembrane protease [H]

Number of amino acids: Translated: 394; Mature: 393

Protein sequence:

>394_residues
MSAGEQLDDWGSSVGRAISVVTVRGVAVRIHPTMLLLVPWVFWHWGGRSAEPLEGTLFGLFLLLAVFVSVAGHELAHAVV
AHRFGLAVRDVVLLPIGGLTRIEQGPLPPRREAAIALAGPVLNLGIALALLPVVSVVLALYEVTSLADVARLLTGTSVGS
LLILTMASNVLLALFNLIPAFPMDGGRLLRAWLSALSERARATRISLVTGYLVALVTLPLGLWLREPTLPLAGLFLAGAA
LLEQRTLQLERVLQRLPVGQFAVWDGGGIDPEQPLSHALQGGPRDVAVVRDGTVVGMLWRENILRLAHVAHLMRVADAMD
HGFAAVSPETSVYEAHRRMLASGHPAVPVVDAGNRYRGIFTSDRLAHVYRYVQASRRPAGRWLTVVRALGFLGR

Sequences:

>Translated_394_residues
MSAGEQLDDWGSSVGRAISVVTVRGVAVRIHPTMLLLVPWVFWHWGGRSAEPLEGTLFGLFLLLAVFVSVAGHELAHAVV
AHRFGLAVRDVVLLPIGGLTRIEQGPLPPRREAAIALAGPVLNLGIALALLPVVSVVLALYEVTSLADVARLLTGTSVGS
LLILTMASNVLLALFNLIPAFPMDGGRLLRAWLSALSERARATRISLVTGYLVALVTLPLGLWLREPTLPLAGLFLAGAA
LLEQRTLQLERVLQRLPVGQFAVWDGGGIDPEQPLSHALQGGPRDVAVVRDGTVVGMLWRENILRLAHVAHLMRVADAMD
HGFAAVSPETSVYEAHRRMLASGHPAVPVVDAGNRYRGIFTSDRLAHVYRYVQASRRPAGRWLTVVRALGFLGR
>Mature_393_residues
SAGEQLDDWGSSVGRAISVVTVRGVAVRIHPTMLLLVPWVFWHWGGRSAEPLEGTLFGLFLLLAVFVSVAGHELAHAVVA
HRFGLAVRDVVLLPIGGLTRIEQGPLPPRREAAIALAGPVLNLGIALALLPVVSVVLALYEVTSLADVARLLTGTSVGSL
LILTMASNVLLALFNLIPAFPMDGGRLLRAWLSALSERARATRISLVTGYLVALVTLPLGLWLREPTLPLAGLFLAGAAL
LEQRTLQLERVLQRLPVGQFAVWDGGGIDPEQPLSHALQGGPRDVAVVRDGTVVGMLWRENILRLAHVAHLMRVADAMDH
GFAAVSPETSVYEAHRRMLASGHPAVPVVDAGNRYRGIFTSDRLAHVYRYVQASRRPAGRWLTVVRALGFLGR

Specific function: Unknown

COG id: COG1994

COG function: function code R; Zn-dependent proteases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR000644
- InterPro:   IPR008915
- InterPro:   IPR016483 [H]

Pfam domain/function: PF00571 CBS; PF02163 Peptidase_M50 [H]

EC number: NA

Molecular weight: Translated: 42421; Mature: 42289

Theoretical pI: Translated: 10.89; Mature: 10.89

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAGEQLDDWGSSVGRAISVVTVRGVAVRIHPTMLLLVPWVFWHWGGRSAEPLEGTLFGL
CCCCCHHHHHHHHHHHHEEEEEEEEEEEEECHHHHHHHHHHHHHCCCCCCCCCHHHHHHH
FLLLAVFVSVAGHELAHAVVAHRFGLAVRDVVLLPIGGLTRIEQGPLPPRREAAIALAGP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCCCCCCCHHHHHHHHHH
VLNLGIALALLPVVSVVLALYEVTSLADVARLLTGTSVGSLLILTMASNVLLALFNLIPA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCC
FPMDGGRLLRAWLSALSERARATRISLVTGYLVALVTLPLGLWLREPTLPLAGLFLAGAA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
LLEQRTLQLERVLQRLPVGQFAVWDGGGIDPEQPLSHALQGGPRDVAVVRDGTVVGMLWR
HHHHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHCCCCCCEEEEECCCEEEHHHH
ENILRLAHVAHLMRVADAMDHGFAAVSPETSVYEAHRRMLASGHPAVPVVDAGNRYRGIF
HHHHHHHHHHHHHHHHHHHHCCCEECCCCHHHHHHHHHHHHCCCCCCEEEECCCCCCCCC
TSDRLAHVYRYVQASRRPAGRWLTVVRALGFLGR
CHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SAGEQLDDWGSSVGRAISVVTVRGVAVRIHPTMLLLVPWVFWHWGGRSAEPLEGTLFGL
CCCCHHHHHHHHHHHHEEEEEEEEEEEEECHHHHHHHHHHHHHCCCCCCCCCHHHHHHH
FLLLAVFVSVAGHELAHAVVAHRFGLAVRDVVLLPIGGLTRIEQGPLPPRREAAIALAGP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCCCCCCCHHHHHHHHHH
VLNLGIALALLPVVSVVLALYEVTSLADVARLLTGTSVGSLLILTMASNVLLALFNLIPA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCC
FPMDGGRLLRAWLSALSERARATRISLVTGYLVALVTLPLGLWLREPTLPLAGLFLAGAA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
LLEQRTLQLERVLQRLPVGQFAVWDGGGIDPEQPLSHALQGGPRDVAVVRDGTVVGMLWR
HHHHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHCCCCCCEEEEECCCEEEHHHH
ENILRLAHVAHLMRVADAMDHGFAAVSPETSVYEAHRRMLASGHPAVPVVDAGNRYRGIF
HHHHHHHHHHHHHHHHHHHHCCCEECCCCHHHHHHHHHHHHCCCCCCEEEECCCCCCCCC
TSDRLAHVYRYVQASRRPAGRWLTVVRALGFLGR
CHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]