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The map label for this gene is atpB [H]

Identifier: 221633217

GI number: 221633217

Start: 1219327

End: 1220217

Strand: Reverse

Name: atpB [H]

Synonym: trd_1234

Alternate gene names: 221633217

Gene position: 1220217-1219327 (Counterclockwise)

Preceding gene: 221633218

Following gene: 221633216

Centisome position: 60.92

GC content: 60.61

Gene sequence:

>891_bases
GTGGAACTCCACATCTCGGTCAAGCCGGAGACGCTCTGGAGTCTCCCGCTCTTCGGTCATTTGACGCTGCGCATTACCAA
CTCCTTCCTGACGATGCTCCTCGTGATGCTCTTCCTCATCATCCTCGGCTCGATCGTGGCTCGGCGGGCGCAACTCATTC
CTGGCCGCTTGCAGTCGGTCGTCGAGATGGTGGTCGAGTTCTTGCTCGGCCTGGTGGAGGGGACTGCAGGCAAGAAACTG
GGACGGCGGATCTTTCCGCTGATCGGTGGTCTCTTCATCTTCATCATCGTCGCGAACTACACCGGTTTGCTCCCTGGTAT
CGGGACGATCGGCATCTGGCATGAGGGGAAGCACGCCCTGGTGGCCGCGAGCGAGGGGGCGACTGGCACCGAGCACGGTG
GTCGGACACTGGTGCCACTCTTCCGCCCGCCGAGCGCCGATCTCAATATGACGCTGGCCATGGCACTGATCAGCTACGTC
GCGTTCCAGGTGGCTGGCATTTCGGCGCATGGCGTCTGGGGCCGCATCAAGCATATGGCGAACCCGCCGTTTCTCTTGCC
GATCGAGATCATCAGTGAACTCTCGCGTATCGTGTCGCTCTCCTTCCGTCTTTTCGGGAATATCTTCGCTGGCGAGACGC
TGTTGACCGTCATGTACGGTATCGCCAATGCGATCAAGATCACGGTGGTCGGCTTGGTGATTCCCGTCATTTTCCTCTAT
CTCGAGGTGCTGTTCGGTTTCATTCAGGCCTTGATCTTCGCGGTGTTGACCTTGATCTACATCGCGTTGGCCTCGGCGCA
CGAGCATGAGGAGGAGCATGAGGCCGAGGGGCATCACCGGGGTAGCGCGCACGACTCGCGAGCGGTCCCGCTGGGGGCCA
GCGGCGATTGA

Upstream 100 bases:

>100_bases
TCTGACGTTGGTAGGGCTGGTACTGGGACTGGCGACGGCGGGGTATTCGCTGTATCAGCTCGCTGTCATTGGTGGGCAGC
GGCGGGGCAGGAGGTAGGGA

Downstream 100 bases:

>100_bases
CGGTCGGTTACGGAACGCTTTGTCTCTGAGCGGAGCGGACGGTTGGTGAAGGGAGGACAGGATCGTGTTCGCGAATGTCA
CTGAGCCGGGTGTCGTCGTG

Product: ATP synthase F0 subunit A

Products: ADP; phosphate; H+

Alternate protein names: ATP synthase F0 sector subunit a; F-ATPase subunit 6 [H]

Number of amino acids: Translated: 296; Mature: 296

Protein sequence:

>296_residues
MELHISVKPETLWSLPLFGHLTLRITNSFLTMLLVMLFLIILGSIVARRAQLIPGRLQSVVEMVVEFLLGLVEGTAGKKL
GRRIFPLIGGLFIFIIVANYTGLLPGIGTIGIWHEGKHALVAASEGATGTEHGGRTLVPLFRPPSADLNMTLAMALISYV
AFQVAGISAHGVWGRIKHMANPPFLLPIEIISELSRIVSLSFRLFGNIFAGETLLTVMYGIANAIKITVVGLVIPVIFLY
LEVLFGFIQALIFAVLTLIYIALASAHEHEEEHEAEGHHRGSAHDSRAVPLGASGD

Sequences:

>Translated_296_residues
MELHISVKPETLWSLPLFGHLTLRITNSFLTMLLVMLFLIILGSIVARRAQLIPGRLQSVVEMVVEFLLGLVEGTAGKKL
GRRIFPLIGGLFIFIIVANYTGLLPGIGTIGIWHEGKHALVAASEGATGTEHGGRTLVPLFRPPSADLNMTLAMALISYV
AFQVAGISAHGVWGRIKHMANPPFLLPIEIISELSRIVSLSFRLFGNIFAGETLLTVMYGIANAIKITVVGLVIPVIFLY
LEVLFGFIQALIFAVLTLIYIALASAHEHEEEHEAEGHHRGSAHDSRAVPLGASGD
>Mature_296_residues
MELHISVKPETLWSLPLFGHLTLRITNSFLTMLLVMLFLIILGSIVARRAQLIPGRLQSVVEMVVEFLLGLVEGTAGKKL
GRRIFPLIGGLFIFIIVANYTGLLPGIGTIGIWHEGKHALVAASEGATGTEHGGRTLVPLFRPPSADLNMTLAMALISYV
AFQVAGISAHGVWGRIKHMANPPFLLPIEIISELSRIVSLSFRLFGNIFAGETLLTVMYGIANAIKITVVGLVIPVIFLY
LEVLFGFIQALIFAVLTLIYIALASAHEHEEEHEAEGHHRGSAHDSRAVPLGASGD

Specific function: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane [H]

COG id: COG0356

COG function: function code C; F0F1-type ATP synthase, subunit a

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase A chain family [H]

Homologues:

Organism=Escherichia coli, GI1790176, Length=274, Percent_Identity=29.5620437956204, Blast_Score=82, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000568
- InterPro:   IPR023011 [H]

Pfam domain/function: PF00119 ATP-synt_A [H]

EC number: 3.6.3.14

Molecular weight: Translated: 32051; Mature: 32051

Theoretical pI: Translated: 7.23; Mature: 7.23

Prosite motif: PS00449 ATPASE_A

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELHISVKPETLWSLPLFGHLTLRITNSFLTMLLVMLFLIILGSIVARRAQLIPGRLQSV
CEEEEECCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHH
VEMVVEFLLGLVEGTAGKKLGRRIFPLIGGLFIFIIVANYTGLLPGIGTIGIWHEGKHAL
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCEEE
VAASEGATGTEHGGRTLVPLFRPPSADLNMTLAMALISYVAFQVAGISAHGVWGRIKHMA
EEECCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHC
NPPFLLPIEIISELSRIVSLSFRLFGNIFAGETLLTVMYGIANAIKITVVGLVIPVIFLY
CCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LEVLFGFIQALIFAVLTLIYIALASAHEHEEEHEAEGHHRGSAHDSRAVPLGASGD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MELHISVKPETLWSLPLFGHLTLRITNSFLTMLLVMLFLIILGSIVARRAQLIPGRLQSV
CEEEEECCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHH
VEMVVEFLLGLVEGTAGKKLGRRIFPLIGGLFIFIIVANYTGLLPGIGTIGIWHEGKHAL
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCEEE
VAASEGATGTEHGGRTLVPLFRPPSADLNMTLAMALISYVAFQVAGISAHGVWGRIKHMA
EEECCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHC
NPPFLLPIEIISELSRIVSLSFRLFGNIFAGETLLTVMYGIANAIKITVVGLVIPVIFLY
CCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LEVLFGFIQALIFAVLTLIYIALASAHEHEEEHEAEGHHRGSAHDSRAVPLGASGD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Borate; diphosphate; HCO3- [C]

Metal ions: Co2+; Fe2+; Mn2+; Zn2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: Ca2+; CN-; Efrapeptin; Ethidiumbromide; Guanidines analogs; Oligomycin; Quercetin; Trialkyl tin derivatives; Venturicidin [C]

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA