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The map label for this gene is ade [H]

Identifier: 221633173

GI number: 221633173

Start: 1178214

End: 1179923

Strand: Reverse

Name: ade [H]

Synonym: trd_1190

Alternate gene names: 221633173

Gene position: 1179923-1178214 (Counterclockwise)

Preceding gene: 221633174

Following gene: 221633172

Centisome position: 58.91

GC content: 64.09

Gene sequence:

>1710_bases
ATGGTTGGACTGGGGATCGAAGCGCTCCGACTGGAGGAGTGGCAACGGCTCCTGCGTGTCGCCCTCGGGGAAGAACCGGC
TGATCTCGTGTTGCGGCAGGCCCGTATCGTGAACGTGGCGAGCGGGGAAATCGAGGAAGCCGATGTCGCGATCGTGTTCG
GGCGCATCGCCGGAATCGGAACGTATCGCGATGGGCATGAGGAGATCGATCTGACTGGAGCCTATCTCGCGCCTTCCTTC
ATCGATGGGCATGTCCATGTCGAAAGTTCGCTCCTCTGGATCGACCAATTCGCGCGTGCGGTGGTCCCGCATGGGACAGG
AGCGGTCGTGACCGACCCGCACGAGATCGCCAATGTGGCTGGCCTCGCGGGCATCCGAGCACTGGCTGAGGCAGCCGCAG
GGCTGCCGCTCGGTGTGTTTTTGACGATACCCTCGTGTGTTCCAGCCAGCCCATACGAAAGTGCCGGAGCGGTCATGGAC
GCGGCTGCGATCGCCGAGGGGCTGAGGTTACCGAACGCGGTTGCGCTGGGCGAGATGATGAACTTTCCGGGTGTCCTCGC
CGGTGAAGCGGAGATCTACGAGAAGCTTCGCCTCCCTGCTCGGCGGCGGGATGGGCACGCACCAGGCTTGCGTGGTTCCC
GCCTCAATGCCTATATCGCATCGGGGATGGGATCCGATCACGAGTCGACGCAACTGGAGGAGGCCCGCGAGAAGCTGCGG
CGGGGACTCCAGGTCATGATCCGGGAGGGATCAACCGAGCACAACCTGCTCGAATTGTTGCCGCTCGTGACCGAGGCTAC
CTACCCGCGCTGCTGCTTCGCGAGCGATGACCGGGATTGCGCGACACTCCTCCACGATGGGCATATGGATGCGATCCTGC
GCAAGGCGATCGCGGCTGGCCTCGATCCGATTCGGGCGATCCGCTTGGCGACGCTCAACACGGCCGAGTATTGGGGGTTG
GACGGTTATGGGCTGGTCGCGCCCGGCTACTGGGCCAATTTGGTCGTATTCGACCGGCTCGACGATATCCGCCCGCGGCT
CGTCCTGTTCCAGGGCGAGGTGGTCGCTCAGGATGGCAAGGCGACCTTCCGGACCAGCCGGACGATTCCTGAGTGGCTCC
TGGATACGGTGCATGTGGCACCGATCGATCGTGCTCGACTTCGCCTGCCTGCTTGCGATCGGATGATCGCCGTGGAAGCG
ATCCCGGGGCAGATCGTGACCCGGGCGATCGAAGTGGAACCGACGGTGCGTGATGGGGAGGTGGTTGCTGATCCGGAACG
CGACTTGGCGAAGCTGGTCGTCGTGGAGCGCCACCGGGCGACGGGACGCGTTGGAGTGGGGTTGGTTCGGGGTTTCGGCT
TGCGGCGTGGTGCGCTGGCTTCGTCCATCGCACACGATGCCCACAACATCGTCGTCGTTGGAGTCGACGATGGGGATATC
TTGGCCGCGATCGATGCGGTCGTTGCCATGCGCGGTGGTCTGGCCGCGGTCGCCGATGGTCTGGTCCGAGCACAACTACC
GCTCCCGGTGGCAGGAATTTTGTCACCGGAACCGCTGGAAACGGTGGCAGAACAGTATGAAGCGGTCGAGCAGGCAGCGC
GCGAGATGGGAAGCCGCGTACCGGCACCGTTCGCGCTGCTCTCGTTCATGGCGCTTTCGGTCATTCCGGAGGCTCGCGTC
ACCGATCATGGCTTGGTCGTGCTGCGCTGA

Upstream 100 bases:

>100_bases
CATCCTTGCCGGAACTGGTCACCGATCTTTTGGAACGACTCAACGAGCTGCTCGAGCGACTCGAAGAGCGTCTGCTCGAT
TGAGAGCGAGGAGGAACGGA

Downstream 100 bases:

>100_bases
GATGACGGTCGATGGCACGGCCCCTCTGCTCGGTGGACGGAACGACCGTCCGCCAGGCTCCGTCGCGAGCGGTTGCGAGC
AAGGAGCTCGTGAGTCCGAG

Product: adenine deaminase

Products: NA

Alternate protein names: Adenase; Adenine aminase [H]

Number of amino acids: Translated: 569; Mature: 569

Protein sequence:

>569_residues
MVGLGIEALRLEEWQRLLRVALGEEPADLVLRQARIVNVASGEIEEADVAIVFGRIAGIGTYRDGHEEIDLTGAYLAPSF
IDGHVHVESSLLWIDQFARAVVPHGTGAVVTDPHEIANVAGLAGIRALAEAAAGLPLGVFLTIPSCVPASPYESAGAVMD
AAAIAEGLRLPNAVALGEMMNFPGVLAGEAEIYEKLRLPARRRDGHAPGLRGSRLNAYIASGMGSDHESTQLEEAREKLR
RGLQVMIREGSTEHNLLELLPLVTEATYPRCCFASDDRDCATLLHDGHMDAILRKAIAAGLDPIRAIRLATLNTAEYWGL
DGYGLVAPGYWANLVVFDRLDDIRPRLVLFQGEVVAQDGKATFRTSRTIPEWLLDTVHVAPIDRARLRLPACDRMIAVEA
IPGQIVTRAIEVEPTVRDGEVVADPERDLAKLVVVERHRATGRVGVGLVRGFGLRRGALASSIAHDAHNIVVVGVDDGDI
LAAIDAVVAMRGGLAAVADGLVRAQLPLPVAGILSPEPLETVAEQYEAVEQAAREMGSRVPAPFALLSFMALSVIPEARV
TDHGLVVLR

Sequences:

>Translated_569_residues
MVGLGIEALRLEEWQRLLRVALGEEPADLVLRQARIVNVASGEIEEADVAIVFGRIAGIGTYRDGHEEIDLTGAYLAPSF
IDGHVHVESSLLWIDQFARAVVPHGTGAVVTDPHEIANVAGLAGIRALAEAAAGLPLGVFLTIPSCVPASPYESAGAVMD
AAAIAEGLRLPNAVALGEMMNFPGVLAGEAEIYEKLRLPARRRDGHAPGLRGSRLNAYIASGMGSDHESTQLEEAREKLR
RGLQVMIREGSTEHNLLELLPLVTEATYPRCCFASDDRDCATLLHDGHMDAILRKAIAAGLDPIRAIRLATLNTAEYWGL
DGYGLVAPGYWANLVVFDRLDDIRPRLVLFQGEVVAQDGKATFRTSRTIPEWLLDTVHVAPIDRARLRLPACDRMIAVEA
IPGQIVTRAIEVEPTVRDGEVVADPERDLAKLVVVERHRATGRVGVGLVRGFGLRRGALASSIAHDAHNIVVVGVDDGDI
LAAIDAVVAMRGGLAAVADGLVRAQLPLPVAGILSPEPLETVAEQYEAVEQAAREMGSRVPAPFALLSFMALSVIPEARV
TDHGLVVLR
>Mature_569_residues
MVGLGIEALRLEEWQRLLRVALGEEPADLVLRQARIVNVASGEIEEADVAIVFGRIAGIGTYRDGHEEIDLTGAYLAPSF
IDGHVHVESSLLWIDQFARAVVPHGTGAVVTDPHEIANVAGLAGIRALAEAAAGLPLGVFLTIPSCVPASPYESAGAVMD
AAAIAEGLRLPNAVALGEMMNFPGVLAGEAEIYEKLRLPARRRDGHAPGLRGSRLNAYIASGMGSDHESTQLEEAREKLR
RGLQVMIREGSTEHNLLELLPLVTEATYPRCCFASDDRDCATLLHDGHMDAILRKAIAAGLDPIRAIRLATLNTAEYWGL
DGYGLVAPGYWANLVVFDRLDDIRPRLVLFQGEVVAQDGKATFRTSRTIPEWLLDTVHVAPIDRARLRLPACDRMIAVEA
IPGQIVTRAIEVEPTVRDGEVVADPERDLAKLVVVERHRATGRVGVGLVRGFGLRRGALASSIAHDAHNIVVVGVDDGDI
LAAIDAVVAMRGGLAAVADGLVRAQLPLPVAGILSPEPLETVAEQYEAVEQAAREMGSRVPAPFALLSFMALSVIPEARV
TDHGLVVLR

Specific function: Unknown

COG id: COG1001

COG function: function code F; Adenine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the adenine deaminase family [H]

Homologues:

Organism=Escherichia coli, GI1790098, Length=566, Percent_Identity=35.6890459363958, Blast_Score=320, Evalue=1e-88,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006679
- InterPro:   IPR006680
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.4.2 [H]

Molecular weight: Translated: 60915; Mature: 60915

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVGLGIEALRLEEWQRLLRVALGEEPADLVLRQARIVNVASGEIEEADVAIVFGRIAGIG
CCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHEEEECCCCCCCCCEEEEEEHHHCCC
TYRDGHEEIDLTGAYLAPSFIDGHVHVESSLLWIDQFARAVVPHGTGAVVTDPHEIANVA
CCCCCCCCEEEEEHHHCHHHCCCEEEECHHHHHHHHHHHHHCCCCCCCEEECHHHHHHHH
GLAGIRALAEAAAGLPLGVFLTIPSCVPASPYESAGAVMDAAAIAEGLRLPNAVALGEMM
HHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHH
NFPGVLAGEAEIYEKLRLPARRRDGHAPGLRGSRLNAYIASGMGSDHESTQLEEAREKLR
CCCCCCCCHHHHHHHHCCCCHHCCCCCCCCCCCCCHHHEECCCCCCCCHHHHHHHHHHHH
RGLQVMIREGSTEHNLLELLPLVTEATYPRCCFASDDRDCATLLHDGHMDAILRKAIAAG
HHHHHHHHCCCCHHHHHHHHHHHHCCCCCCEEECCCCCHHHHHHHCCCHHHHHHHHHHHC
LDPIRAIRLATLNTAEYWGLDGYGLVAPGYWANLVVFDRLDDIRPRLVLFQGEVVAQDGK
CCHHHHEEEEEECCHHHCCCCCCCEECCCCHHEEEEEECCCCCCCEEEEEECCEEECCCC
ATFRTSRTIPEWLLDTVHVAPIDRARLRLPACDRMIAVEAIPGQIVTRAIEVEPTVRDGE
CEEEECCCCHHHHHHHHCCCCCCHHHCCCCCCCCEEEEECCCHHHHHEEEEECCCCCCCC
VVADPERDLAKLVVVERHRATGRVGVGLVRGFGLRRGALASSIAHDAHNIVVVGVDDGDI
EEECCHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHCCCCEEEEEECCCCH
LAAIDAVVAMRGGLAAVADGLVRAQLPLPVAGILSPEPLETVAEQYEAVEQAAREMGSRV
HHHHHHHHHHCCCHHHHHCCHHEECCCCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHCCC
PAPFALLSFMALSVIPEARVTDHGLVVLR
CCHHHHHHHHHHHHCCCCCCCCCCEEEEC
>Mature Secondary Structure
MVGLGIEALRLEEWQRLLRVALGEEPADLVLRQARIVNVASGEIEEADVAIVFGRIAGIG
CCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHEEEECCCCCCCCCEEEEEEHHHCCC
TYRDGHEEIDLTGAYLAPSFIDGHVHVESSLLWIDQFARAVVPHGTGAVVTDPHEIANVA
CCCCCCCCEEEEEHHHCHHHCCCEEEECHHHHHHHHHHHHHCCCCCCCEEECHHHHHHHH
GLAGIRALAEAAAGLPLGVFLTIPSCVPASPYESAGAVMDAAAIAEGLRLPNAVALGEMM
HHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHH
NFPGVLAGEAEIYEKLRLPARRRDGHAPGLRGSRLNAYIASGMGSDHESTQLEEAREKLR
CCCCCCCCHHHHHHHHCCCCHHCCCCCCCCCCCCCHHHEECCCCCCCCHHHHHHHHHHHH
RGLQVMIREGSTEHNLLELLPLVTEATYPRCCFASDDRDCATLLHDGHMDAILRKAIAAG
HHHHHHHHCCCCHHHHHHHHHHHHCCCCCCEEECCCCCHHHHHHHCCCHHHHHHHHHHHC
LDPIRAIRLATLNTAEYWGLDGYGLVAPGYWANLVVFDRLDDIRPRLVLFQGEVVAQDGK
CCHHHHEEEEEECCHHHCCCCCCCEECCCCHHEEEEEECCCCCCCEEEEEECCEEECCCC
ATFRTSRTIPEWLLDTVHVAPIDRARLRLPACDRMIAVEAIPGQIVTRAIEVEPTVRDGE
CEEEECCCCHHHHHHHHCCCCCCHHHCCCCCCCCEEEEECCCHHHHHEEEEECCCCCCCC
VVADPERDLAKLVVVERHRATGRVGVGLVRGFGLRRGALASSIAHDAHNIVVVGVDDGDI
EEECCHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHCCCCEEEEEECCCCH
LAAIDAVVAMRGGLAAVADGLVRAQLPLPVAGILSPEPLETVAEQYEAVEQAAREMGSRV
HHHHHHHHHHCCCHHHHHCCHHEECCCCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHCCC
PAPFALLSFMALSVIPEARVTDHGLVVLR
CCHHHHHHHHHHHHCCCCCCCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA