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The map label for this gene is ald [H]

Identifier: 221633041

GI number: 221633041

Start: 1026627

End: 1027754

Strand: Reverse

Name: ald [H]

Synonym: trd_1056

Alternate gene names: 221633041

Gene position: 1027754-1026627 (Counterclockwise)

Preceding gene: 221633046

Following gene: 221633040

Centisome position: 51.31

GC content: 60.2

Gene sequence:

>1128_bases
ATGGGAGGTCGAGCCTTGATCATAGGGATTCCACGCGAGAGGAAACTCCGCGAATATCGTGTTGCCCAGCCACCCCACGG
GGTACGCGAACTGGTTCGTCATGGACACCGAGTGCTCGTGGAGCGTGGGGCGGGGGTCGGCAGCGGATTCACCGACACCG
ACTACGAAGCGGCAGGAGCCGAATTGGTCGACGATGCGGAGGCAGTGTGGTCGCAATCCGAAATGATCGTCAAGGTCAAG
GAGCCGATCGAGTCGGAGTATCGCTTTCTCCGCCCCGGCCTCATTTTGTTCACGTTTCTCCATCTCGCGGCTGACGAGCG
TTTGACCCGCGAACTCATGGCGCGTGAGGTCATTGCGATTGCCTATGAAACGGTGCAATTACCGGATGGGTCGCTCCCGC
TCCTCGCGCCGATGAGCGAGGTGGCTGGTCGACTGGCTATCCAGGTTGGGGCCTACTATTTGATGGAACCATATGGTGGG
CGGGGCGTTTTGCTGGGCGGTGTTCCCGGTGTCGCACCGGGCCGCGTCGTCATCCTCGGGGGTGGCACGGTTGGGACCAA
TGCTGCACAGATGGCGTTGGGCCTGGGTGCTGATGTCCTGTTGTTCGATATCAATGTCGAACGACTCCGTTACCTGGAGC
AGATCTTGCACGGACGATTCCAGACGCGGGTTTCCAGTGAACAGGTGATCGGTGAGGCGATACGGGAGGCTGATCTCGTC
ATCGGGGCTGTCTTGATTCCTGGTGCCCGTGCACCCAAACTGGTTACTCGTCAGATGGTTCGGGCGATGCGACCAGGGAG
CGTCATCGTCGACGTCTCGATCGATCAGGGAGGGTGCGTCGAGACTGCACGGCCGACGACACATGACGCGCCGGTCTACG
ACGTGGACGGTGTGCTGCACTACATGGTGACGAATATGCCGGGGGCTGTTCCCCGAACGAGCACATTCGCACTCAGCAAT
GTGACACTGCGGTACGTCCTGGAATTGGCGGACCTCGGTTTGGTCGCTGCTGTCCAGCGCGACCGAGCGCTGGCCAAAGG
CGTTAATGTGTTTAGAGGAAGGATCACGCATCCTTCCGTTGCGGAGTCGTTCGGTCTGCCGTACGTGCCTCTCGATGAGC
TCTTGTAG

Upstream 100 bases:

>100_bases
CGGTCACCGCTTGTGAGGAAGTCGAGCTCTCGGCGACAATAAGCGCCGTCCTGCCGGTTGGGGCGGCATGGGCGGCAGGA
CGCGCGAGCGGCATGCATGG

Downstream 100 bases:

>100_bases
AAGGGAGTAGCACGTGCGGTGAGCTTTCGTGTTTTCTCGCGATTCGGACGGAGAGTGGAGGCAGGACCGATGCAGCAGGC
GATCGAGGAGTTCTTGACTG

Product: alanine dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 375; Mature: 374

Protein sequence:

>375_residues
MGGRALIIGIPRERKLREYRVAQPPHGVRELVRHGHRVLVERGAGVGSGFTDTDYEAAGAELVDDAEAVWSQSEMIVKVK
EPIESEYRFLRPGLILFTFLHLAADERLTRELMAREVIAIAYETVQLPDGSLPLLAPMSEVAGRLAIQVGAYYLMEPYGG
RGVLLGGVPGVAPGRVVILGGGTVGTNAAQMALGLGADVLLFDINVERLRYLEQILHGRFQTRVSSEQVIGEAIREADLV
IGAVLIPGARAPKLVTRQMVRAMRPGSVIVDVSIDQGGCVETARPTTHDAPVYDVDGVLHYMVTNMPGAVPRTSTFALSN
VTLRYVLELADLGLVAAVQRDRALAKGVNVFRGRITHPSVAESFGLPYVPLDELL

Sequences:

>Translated_375_residues
MGGRALIIGIPRERKLREYRVAQPPHGVRELVRHGHRVLVERGAGVGSGFTDTDYEAAGAELVDDAEAVWSQSEMIVKVK
EPIESEYRFLRPGLILFTFLHLAADERLTRELMAREVIAIAYETVQLPDGSLPLLAPMSEVAGRLAIQVGAYYLMEPYGG
RGVLLGGVPGVAPGRVVILGGGTVGTNAAQMALGLGADVLLFDINVERLRYLEQILHGRFQTRVSSEQVIGEAIREADLV
IGAVLIPGARAPKLVTRQMVRAMRPGSVIVDVSIDQGGCVETARPTTHDAPVYDVDGVLHYMVTNMPGAVPRTSTFALSN
VTLRYVLELADLGLVAAVQRDRALAKGVNVFRGRITHPSVAESFGLPYVPLDELL
>Mature_374_residues
GGRALIIGIPRERKLREYRVAQPPHGVRELVRHGHRVLVERGAGVGSGFTDTDYEAAGAELVDDAEAVWSQSEMIVKVKE
PIESEYRFLRPGLILFTFLHLAADERLTRELMAREVIAIAYETVQLPDGSLPLLAPMSEVAGRLAIQVGAYYLMEPYGGR
GVLLGGVPGVAPGRVVILGGGTVGTNAAQMALGLGADVLLFDINVERLRYLEQILHGRFQTRVSSEQVIGEAIREADLVI
GAVLIPGARAPKLVTRQMVRAMRPGSVIVDVSIDQGGCVETARPTTHDAPVYDVDGVLHYMVTNMPGAVPRTSTFALSNV
TLRYVLELADLGLVAAVQRDRALAKGVNVFRGRITHPSVAESFGLPYVPLDELL

Specific function: May play a role in cell wall synthesis as L-alanine is an important constituent of the peptidoglycan layer [H]

COG id: COG0686

COG function: function code E; Alanine dehydrogenase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AlaDH/PNT family [H]

Homologues:

Organism=Homo sapiens, GI122939155, Length=350, Percent_Identity=29.1428571428571, Blast_Score=143, Evalue=3e-34,
Organism=Homo sapiens, GI122939153, Length=350, Percent_Identity=29.1428571428571, Blast_Score=143, Evalue=3e-34,
Organism=Escherichia coli, GI1787887, Length=381, Percent_Identity=34.3832020997375, Blast_Score=162, Evalue=5e-41,
Organism=Caenorhabditis elegans, GI17550456, Length=350, Percent_Identity=29.4285714285714, Blast_Score=149, Evalue=2e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007698
- InterPro:   IPR008143
- InterPro:   IPR007886
- InterPro:   IPR008141 [H]

Pfam domain/function: PF01262 AlaDh_PNT_C; PF05222 AlaDh_PNT_N [H]

EC number: =1.4.1.1 [H]

Molecular weight: Translated: 40526; Mature: 40394

Theoretical pI: Translated: 6.33; Mature: 6.33

Prosite motif: PS00837 ALADH_PNT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGGRALIIGIPRERKLREYRVAQPPHGVRELVRHGHRVLVERGAGVGSGFTDTDYEAAGA
CCCCEEEEECCCHHHHHHHCCCCCCHHHHHHHHCCCEEEEECCCCCCCCCCCCCCHHCCC
ELVDDAEAVWSQSEMIVKVKEPIESEYRFLRPGLILFTFLHLAADERLTRELMAREVIAI
HHHHHHHHHHCCCCEEEEECCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AYETVQLPDGSLPLLAPMSEVAGRLAIQVGAYYLMEPYGGRGVLLGGVPGVAPGRVVILG
HHHEEECCCCCCCCCCCHHHHHHHHHHHCCEEEEECCCCCCEEEEECCCCCCCCEEEEEE
GGTVGTNAAQMALGLGADVLLFDINVERLRYLEQILHGRFQTRVSSEQVIGEAIREADLV
CCCCCCCHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
IGAVLIPGARAPKLVTRQMVRAMRPGSVIVDVSIDQGGCVETARPTTHDAPVYDVDGVLH
EEHEECCCCCCHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCCCCCEEHHHHHH
YMVTNMPGAVPRTSTFALSNVTLRYVLELADLGLVAAVQRDRALAKGVNVFRGRITHPSV
HHHHCCCCCCCCCCEEEHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCCCHH
AESFGLPYVPLDELL
HHHCCCCCCCHHHCC
>Mature Secondary Structure 
GGRALIIGIPRERKLREYRVAQPPHGVRELVRHGHRVLVERGAGVGSGFTDTDYEAAGA
CCCEEEEECCCHHHHHHHCCCCCCHHHHHHHHCCCEEEEECCCCCCCCCCCCCCHHCCC
ELVDDAEAVWSQSEMIVKVKEPIESEYRFLRPGLILFTFLHLAADERLTRELMAREVIAI
HHHHHHHHHHCCCCEEEEECCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AYETVQLPDGSLPLLAPMSEVAGRLAIQVGAYYLMEPYGGRGVLLGGVPGVAPGRVVILG
HHHEEECCCCCCCCCCCHHHHHHHHHHHCCEEEEECCCCCCEEEEECCCCCCCCEEEEEE
GGTVGTNAAQMALGLGADVLLFDINVERLRYLEQILHGRFQTRVSSEQVIGEAIREADLV
CCCCCCCHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
IGAVLIPGARAPKLVTRQMVRAMRPGSVIVDVSIDQGGCVETARPTTHDAPVYDVDGVLH
EEHEECCCCCCHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCCCCCEEHHHHHH
YMVTNMPGAVPRTSTFALSNVTLRYVLELADLGLVAAVQRDRALAKGVNVFRGRITHPSV
HHHHCCCCCCCCCCEEEHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCCCHH
AESFGLPYVPLDELL
HHHCCCCCCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA