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The map label for this gene is mprF [H]

Identifier: 221633005

GI number: 221633005

Start: 976651

End: 979422

Strand: Reverse

Name: mprF [H]

Synonym: trd_1014

Alternate gene names: 221633005

Gene position: 979422-976651 (Counterclockwise)

Preceding gene: 221633006

Following gene: 221633004

Centisome position: 48.9

GC content: 59.13

Gene sequence:

>2772_bases
ATGACCCATCCGCTCGCCCGCCGCGGGGTGGAGCAGCGGCAGCTCGCTGGGCTCATAACCCAGAGGTCGTGGGTTCGAAT
CCCACCCCCGCTACCAGAACGACGAGCCCTCGGCAGCACTGCCGAGGGCTCGTCACATGAGGAGGACGACGTGTCGGGCG
ATTTCTCGATTTCAGGCAGCTGGTCCCGGTTTCGCGCGTTTGCCGCCCGAGCGTGGTTTTTCATCTTCGTTTTGCTGGTG
ACCTTGTTTCTCTTGCGGCATCGAACTGAACTGGCGGAATTGCGTCATTTCCCAATTGTCCGACCACAATGGCTACTCCT
GACCAGTGCTGCCCAAGGGCTCGTTCTGCTGTCCATCATCTGGCAATTGCGTCTCCTGCTCGCTGCTTCGGGGTTTTCTG
TACCGCTCTCGAGACTCTTCCGGGCTGATCTCCATCGGGTCGCGGTTAGTACTGTCACCCCAGCTGGCTCGGCAGCCGGC
GTCCTGGTCTTCGCGGCGGATCTGCAAGCAGTAGGTGTTCCGACGACAGCAGCAGTGGCTGCCACAGTAACCTATGGTGT
CGTGGGATTGTTCTCTTTCCTGCTCTTGCTTCCACTCACTGTTCTGCTCCTCGTCACTCGACAGCTTATCTCACTACCTC
TCTCCTTGCTTCTCTTTCTCGGCGCTCTCGTGCCCATCGTGTTGCTTCTCTTGCTACCGTGGGCACTGCGTCACGGTATG
CCACGCTTGTCGAGGATGTCGCTCGTTCGGGGATTCGTGGAGACCGCTCGCTGGTACCGAATTTCCGGACTCGGACGAGT
TCTCGTCCTGGCACTCGCAGTCGATCTTCTCAATGTTGCCATTCTGTATGGTGGAGTGCGAGTCGTCGGCGGGGCGTTGA
CGCTCGCTGAAGCACTCATCGCCTATCAAGGTGCCTATCTCTTTGCATTCCTGATTCCATTCGCGCAGGGAAGCGGAGCG
GTCGAACTCGCTGGGACGAGCTTGCTGACGGCTCTGGGTCTCCCTGCACCGACTGCGCTCGCGGCCGTGTTGCTCTGGCG
GGCCCATGAACTTTGGTTCCCTTTTCTGCTCGGTACTGCACTCTCGGTGCAGCGGGAGCCGGTGATCCGCCGTGCATTGG
ATCGCCTTCCCGCATTACTGCTCCTTTGGTCGGGAATCGTGGGCATGGTCGGGCTTCTCGAACCGCACCATCACCGAGTG
GTGCCTCGTCGTCTGGAGACCACTGGACTGCTCGAACCGTGGGAGTTCTCTCGCAATCTCGAATTACTCGTGGCTTTCCT
GTCGATCATCATCGCTTGGCAGGTGTGGCGCCGAAAACGTACAGGTTGGCTTGTGGCGACACTGCTGCTTAGCGTTTCGT
TGTTCCATCAGTTGATCGGGCGACGCGATGAACTCCTTTTGGCGCTCACAATGCTCGCGCTCGGGCTTCTGCTCGTGCGC
TGGCGCACCTATCGAGTTCGGTCAGATATCCCGAGTATTTGGAGGGGATTCGCTCTGGCCGGTCTTGGCCTCACTACCAC
GTTGCTCTATGGCACGATCGGGCTCATGCTCTTGAGCCGACACGCGCTCGTTCCCAAGCATCTCTCGTTTTGGGATGCAC
TCACGGTACTGATACGATCGGCATGGGGCTTCTTGCCCTGGGCTGTCGAACCAGTGTCGCGTTACGGAGGGTGGTTTCTC
GACTCTGTCACGCTGCTCGCGGGTGCATCCCTTCTGAACGCCGCCTGGAGCATCGGGCGGCCGGTGATCTGGCGGTCATG
GGGCTACGAATCAGAACGGCAGCGAGCACGAGCCATCATTCAAGCATGCGGCAACTCGTCCCTCGACTTCTTCAAGTTTT
GGCCTGACAAGCTCTTCTTCTTCCCGCGAGAAGTGCGTGGAGTGGTGAGTTACCGCATCGTCGGTCGGGTCGCACTGGTA
CTCGGTGATCCCAATGTGTGTGGGGAGCGATTCGGGACAGCTCTGGACGGCTTTCTCGATTTCTGCGATCTGAACGACTG
GGAACCAGCATTTCATCAAGTTGGGGAGCAGTATCTGGCCGACTACCGTGCGCGAGGGCTGCGATTTTTCAAAATAGGCG
AAGAGGCAGTCGTTGATCTCACAACGTGGTCGCTCGATCGCCCAGGGTTGAAAGAGTTGCGCTACCTCGTGCGGAGATCG
CAGCGCGAGAACTACCGGTTCGAGGTGCTCGAGCCGCCGCTTCCCGACGATATGGTCGAAGAACTCGCGGACGTCTCCAA
TGAATGGTTGTCGCTGCCAGGTCGACGCGAACACGGGTTCACGCAGGGACAATTTTCCCGTGCCTATGTGCGATCGACCC
CTGTCGCGCTGATCCGGGATCCGACTGGTAAAGTCGTCGCCTTCGCGAATCTCATACCGAGTGGAGTACCAGGCCAGGCG
ACGATCGACCTCATGCGGCGTCGGCACCAGCCGTACGGTGCGATGGATGTCTTGTTCGCCCTGCTCTTCCAGTGGCTGCG
TGAGCAGGGATATACATCGTTCTCGCTGGGTCTAGCTCCGCTGAGTGGAGTAGACCTACCGCTTGTGGGGACGGACCCGA
TTCGGGAACACTTTTTCCGGCTCATCGAACCATTTTTCTCTGTCCAAGGGCTCCGCCATTTCAAGGCCAAGTTCGATCCT
CGCTGGGAACCGCGCTTTCTCGTCTTCCGCTCAGCGAGTGCACTCCCCGCTATCGGATTAGCCCTGTTGAAAGCGACTTC
CACCGAGGTCTCGCACGTGGACAGCGATCTTCCCGAGTTGCAGATCGCCTGA

Upstream 100 bases:

>100_bases
CCGAACCGGGTCGTGCCCCACACCAGCGCCGGAGAGTACTGCGCGGGCAACCGCGTGGGAGGCGAGGCCGCTGCGCGCAC
ACCCGACGAGAAGGTTCGCG

Downstream 100 bases:

>100_bases
GTCACCTGTCTCTCCTGGTCAGGCATCCCTCGTATTGGCTAGGTCTCTCATACTTCTCACCTATGTGGCGGGACTTCTCC
CGTGCCGTGGAAACGATGAT

Product: hypothetical protein

Products: NA

Alternate protein names: Lysylphosphatidylglycerol synthase; LPG synthase [H]

Number of amino acids: Translated: 923; Mature: 922

Protein sequence:

>923_residues
MTHPLARRGVEQRQLAGLITQRSWVRIPPPLPERRALGSTAEGSSHEEDDVSGDFSISGSWSRFRAFAARAWFFIFVLLV
TLFLLRHRTELAELRHFPIVRPQWLLLTSAAQGLVLLSIIWQLRLLLAASGFSVPLSRLFRADLHRVAVSTVTPAGSAAG
VLVFAADLQAVGVPTTAAVAATVTYGVVGLFSFLLLLPLTVLLLVTRQLISLPLSLLLFLGALVPIVLLLLLPWALRHGM
PRLSRMSLVRGFVETARWYRISGLGRVLVLALAVDLLNVAILYGGVRVVGGALTLAEALIAYQGAYLFAFLIPFAQGSGA
VELAGTSLLTALGLPAPTALAAVLLWRAHELWFPFLLGTALSVQREPVIRRALDRLPALLLLWSGIVGMVGLLEPHHHRV
VPRRLETTGLLEPWEFSRNLELLVAFLSIIIAWQVWRRKRTGWLVATLLLSVSLFHQLIGRRDELLLALTMLALGLLLVR
WRTYRVRSDIPSIWRGFALAGLGLTTTLLYGTIGLMLLSRHALVPKHLSFWDALTVLIRSAWGFLPWAVEPVSRYGGWFL
DSVTLLAGASLLNAAWSIGRPVIWRSWGYESERQRARAIIQACGNSSLDFFKFWPDKLFFFPREVRGVVSYRIVGRVALV
LGDPNVCGERFGTALDGFLDFCDLNDWEPAFHQVGEQYLADYRARGLRFFKIGEEAVVDLTTWSLDRPGLKELRYLVRRS
QRENYRFEVLEPPLPDDMVEELADVSNEWLSLPGRREHGFTQGQFSRAYVRSTPVALIRDPTGKVVAFANLIPSGVPGQA
TIDLMRRRHQPYGAMDVLFALLFQWLREQGYTSFSLGLAPLSGVDLPLVGTDPIREHFFRLIEPFFSVQGLRHFKAKFDP
RWEPRFLVFRSASALPAIGLALLKATSTEVSHVDSDLPELQIA

Sequences:

>Translated_923_residues
MTHPLARRGVEQRQLAGLITQRSWVRIPPPLPERRALGSTAEGSSHEEDDVSGDFSISGSWSRFRAFAARAWFFIFVLLV
TLFLLRHRTELAELRHFPIVRPQWLLLTSAAQGLVLLSIIWQLRLLLAASGFSVPLSRLFRADLHRVAVSTVTPAGSAAG
VLVFAADLQAVGVPTTAAVAATVTYGVVGLFSFLLLLPLTVLLLVTRQLISLPLSLLLFLGALVPIVLLLLLPWALRHGM
PRLSRMSLVRGFVETARWYRISGLGRVLVLALAVDLLNVAILYGGVRVVGGALTLAEALIAYQGAYLFAFLIPFAQGSGA
VELAGTSLLTALGLPAPTALAAVLLWRAHELWFPFLLGTALSVQREPVIRRALDRLPALLLLWSGIVGMVGLLEPHHHRV
VPRRLETTGLLEPWEFSRNLELLVAFLSIIIAWQVWRRKRTGWLVATLLLSVSLFHQLIGRRDELLLALTMLALGLLLVR
WRTYRVRSDIPSIWRGFALAGLGLTTTLLYGTIGLMLLSRHALVPKHLSFWDALTVLIRSAWGFLPWAVEPVSRYGGWFL
DSVTLLAGASLLNAAWSIGRPVIWRSWGYESERQRARAIIQACGNSSLDFFKFWPDKLFFFPREVRGVVSYRIVGRVALV
LGDPNVCGERFGTALDGFLDFCDLNDWEPAFHQVGEQYLADYRARGLRFFKIGEEAVVDLTTWSLDRPGLKELRYLVRRS
QRENYRFEVLEPPLPDDMVEELADVSNEWLSLPGRREHGFTQGQFSRAYVRSTPVALIRDPTGKVVAFANLIPSGVPGQA
TIDLMRRRHQPYGAMDVLFALLFQWLREQGYTSFSLGLAPLSGVDLPLVGTDPIREHFFRLIEPFFSVQGLRHFKAKFDP
RWEPRFLVFRSASALPAIGLALLKATSTEVSHVDSDLPELQIA
>Mature_922_residues
THPLARRGVEQRQLAGLITQRSWVRIPPPLPERRALGSTAEGSSHEEDDVSGDFSISGSWSRFRAFAARAWFFIFVLLVT
LFLLRHRTELAELRHFPIVRPQWLLLTSAAQGLVLLSIIWQLRLLLAASGFSVPLSRLFRADLHRVAVSTVTPAGSAAGV
LVFAADLQAVGVPTTAAVAATVTYGVVGLFSFLLLLPLTVLLLVTRQLISLPLSLLLFLGALVPIVLLLLLPWALRHGMP
RLSRMSLVRGFVETARWYRISGLGRVLVLALAVDLLNVAILYGGVRVVGGALTLAEALIAYQGAYLFAFLIPFAQGSGAV
ELAGTSLLTALGLPAPTALAAVLLWRAHELWFPFLLGTALSVQREPVIRRALDRLPALLLLWSGIVGMVGLLEPHHHRVV
PRRLETTGLLEPWEFSRNLELLVAFLSIIIAWQVWRRKRTGWLVATLLLSVSLFHQLIGRRDELLLALTMLALGLLLVRW
RTYRVRSDIPSIWRGFALAGLGLTTTLLYGTIGLMLLSRHALVPKHLSFWDALTVLIRSAWGFLPWAVEPVSRYGGWFLD
SVTLLAGASLLNAAWSIGRPVIWRSWGYESERQRARAIIQACGNSSLDFFKFWPDKLFFFPREVRGVVSYRIVGRVALVL
GDPNVCGERFGTALDGFLDFCDLNDWEPAFHQVGEQYLADYRARGLRFFKIGEEAVVDLTTWSLDRPGLKELRYLVRRSQ
RENYRFEVLEPPLPDDMVEELADVSNEWLSLPGRREHGFTQGQFSRAYVRSTPVALIRDPTGKVVAFANLIPSGVPGQAT
IDLMRRRHQPYGAMDVLFALLFQWLREQGYTSFSLGLAPLSGVDLPLVGTDPIREHFFRLIEPFFSVQGLRHFKAKFDPR
WEPRFLVFRSASALPAIGLALLKATSTEVSHVDSDLPELQIA

Specific function: Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), one of the components of the bacterial membrane with a positive net charge. LPG synthesis contribu

COG id: COG2898

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the LPG synthase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016181
- InterPro:   IPR022791 [H]

Pfam domain/function: PF03706 UPF0104 [H]

EC number: =2.3.2.3 [H]

Molecular weight: Translated: 103026; Mature: 102895

Theoretical pI: Translated: 10.48; Mature: 10.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHPLARRGVEQRQLAGLITQRSWVRIPPPLPERRALGSTAEGSSHEEDDVSGDFSISGS
CCCCHHHCCCHHHHHHHHHHCCCEEECCCCCCCHHHCCCCCCCCCCCCCCCCCCEEECCC
WSRFRAFAARAWFFIFVLLVTLFLLRHRTELAELRHFPIVRPQWLLLTSAAQGLVLLSII
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
WQLRLLLAASGFSVPLSRLFRADLHRVAVSTVTPAGSAAGVLVFAADLQAVGVPTTAAVA
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECHHHCCCCHHHHHH
ATVTYGVVGLFSFLLLLPLTVLLLVTRQLISLPLSLLLFLGALVPIVLLLLLPWALRHGM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PRLSRMSLVRGFVETARWYRISGLGRVLVLALAVDLLNVAILYGGVRVVGGALTLAEALI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
AYQGAYLFAFLIPFAQGSGAVELAGTSLLTALGLPAPTALAAVLLWRAHELWFPFLLGTA
HHHHHHHHHHHHHHHCCCCCEEECHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LSVQREPVIRRALDRLPALLLLWSGIVGMVGLLEPHHHRVVPRRLETTGLLEPWEFSRNL
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCHHHHHCCCCCCHHHCCCH
ELLVAFLSIIIAWQVWRRKRTGWLVATLLLSVSLFHQLIGRRDELLLALTMLALGLLLVR
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
WRTYRVRSDIPSIWRGFALAGLGLTTTLLYGTIGLMLLSRHALVPKHLSFWDALTVLIRS
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
AWGFLPWAVEPVSRYGGWFLDSVTLLAGASLLNAAWSIGRPVIWRSWGYESERQRARAII
HHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHH
QACGNSSLDFFKFWPDKLFFFPREVRGVVSYRIVGRVALVLGDPNVCGERFGTALDGFLD
HHHCCCCCCHHHHCCHHHHHCHHHHHHHHHHHHHHHEEEEECCCCHHHHHHHHHHHHHHH
FCDLNDWEPAFHQVGEQYLADYRARGLRFFKIGEEAVVDLTTWSLDRPGLKELRYLVRRS
HHCCCCCCHHHHHHHHHHHHHHHHCCEEEEEECCHHEEEEEECCCCCCCHHHHHHHHHHH
QRENYRFEVLEPPLPDDMVEELADVSNEWLSLPGRREHGFTQGQFSRAYVRSTPVALIRD
HCCCCCEEEECCCCCHHHHHHHHHCCHHHHCCCCCCCCCCCCCHHHHHHHHCCCEEEEEC
PTGKVVAFANLIPSGVPGQATIDLMRRRHQPYGAMDVLFALLFQWLREQGYTSFSLGLAP
CCCCEEEEHHHCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCEEEECCCC
LSGVDLPLVGTDPIREHFFRLIEPFFSVQGLRHFKAKFDPRWEPRFLVFRSASALPAIGL
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCHHHHH
ALLKATSTEVSHVDSDLPELQIA
HHHHHCCHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
THPLARRGVEQRQLAGLITQRSWVRIPPPLPERRALGSTAEGSSHEEDDVSGDFSISGS
CCCHHHCCCHHHHHHHHHHCCCEEECCCCCCCHHHCCCCCCCCCCCCCCCCCCEEECCC
WSRFRAFAARAWFFIFVLLVTLFLLRHRTELAELRHFPIVRPQWLLLTSAAQGLVLLSII
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
WQLRLLLAASGFSVPLSRLFRADLHRVAVSTVTPAGSAAGVLVFAADLQAVGVPTTAAVA
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECHHHCCCCHHHHHH
ATVTYGVVGLFSFLLLLPLTVLLLVTRQLISLPLSLLLFLGALVPIVLLLLLPWALRHGM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PRLSRMSLVRGFVETARWYRISGLGRVLVLALAVDLLNVAILYGGVRVVGGALTLAEALI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
AYQGAYLFAFLIPFAQGSGAVELAGTSLLTALGLPAPTALAAVLLWRAHELWFPFLLGTA
HHHHHHHHHHHHHHHCCCCCEEECHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LSVQREPVIRRALDRLPALLLLWSGIVGMVGLLEPHHHRVVPRRLETTGLLEPWEFSRNL
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCHHHHHCCCCCCHHHCCCH
ELLVAFLSIIIAWQVWRRKRTGWLVATLLLSVSLFHQLIGRRDELLLALTMLALGLLLVR
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
WRTYRVRSDIPSIWRGFALAGLGLTTTLLYGTIGLMLLSRHALVPKHLSFWDALTVLIRS
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
AWGFLPWAVEPVSRYGGWFLDSVTLLAGASLLNAAWSIGRPVIWRSWGYESERQRARAII
HHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHH
QACGNSSLDFFKFWPDKLFFFPREVRGVVSYRIVGRVALVLGDPNVCGERFGTALDGFLD
HHHCCCCCCHHHHCCHHHHHCHHHHHHHHHHHHHHHEEEEECCCCHHHHHHHHHHHHHHH
FCDLNDWEPAFHQVGEQYLADYRARGLRFFKIGEEAVVDLTTWSLDRPGLKELRYLVRRS
HHCCCCCCHHHHHHHHHHHHHHHHCCEEEEEECCHHEEEEEECCCCCCCHHHHHHHHHHH
QRENYRFEVLEPPLPDDMVEELADVSNEWLSLPGRREHGFTQGQFSRAYVRSTPVALIRD
HCCCCCEEEECCCCCHHHHHHHHHCCHHHHCCCCCCCCCCCCCHHHHHHHHCCCEEEEEC
PTGKVVAFANLIPSGVPGQATIDLMRRRHQPYGAMDVLFALLFQWLREQGYTSFSLGLAP
CCCCEEEEHHHCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCEEEECCCC
LSGVDLPLVGTDPIREHFFRLIEPFFSVQGLRHFKAKFDPRWEPRFLVFRSASALPAIGL
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCHHHHH
ALLKATSTEVSHVDSDLPELQIA
HHHHHCCHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8946165; 9384377 [H]