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The map label for this gene is minD [H]

Identifier: 221633003

GI number: 221633003

Start: 974255

End: 975514

Strand: Reverse

Name: minD [H]

Synonym: trd_1012

Alternate gene names: 221633003

Gene position: 975514-974255 (Counterclockwise)

Preceding gene: 221633004

Following gene: 221633002

Centisome position: 48.7

GC content: 60.48

Gene sequence:

>1260_bases
TTGCGCATCGTGATCGTCGACGATATCCCGGAGAGTCGGGACAACCTCGAACGACTGCTTTTTTTCGAACCGGACTTCCA
GGTTGTCGGCAAAGCGGCGCGCGGCGAAGAAGCGATCGACCTTGTGCTTCGACTGGCTCCACACGTCGTCCTGCTCGACC
AGACACTTCCAGACCTCGATGGGATCGAGGTCGCGAGCGCGATCACGGCTCGCGCGCCAGGAATCGGGGTCATTCTGCTC
GGCGTGGAACAGGATCCCGAGATCTTGCGTCGGGCGATGCTGGCCGGTGCACGGGAGTATCTCAGTAAGCCATTCAGCTA
CGATGACCTCATCGAGGCTGTCCGGCGTGTGGGGCACGTTGCGAATCCACAGTCGATGATGCCCGCTCCCGCGACTGTCT
TTGCTGCTCCCCTCGCTCCGGTGCACGAACCAGTCACGAGGCGCGAGGGGCAAGTGGTTGTGGTACTCGGCAGCAAGGGC
GGTGTCGGTCGAACGTTCATCGCCACCAACCTCGCGATTTGTCTTCAGCGCGCGCTGCAACGTGAGGTCGTACTAGTCGA
TGCCGACCTCATGCGCGGAGACGTTGCCGTCCTTCTCAATCTCCCGGCGCACCGTTCCTGGACGGATCTGGCGCGGCTCG
CTGGTCCACTCGATGGCGAACTCATCCACGAGTTCGTGACCCGTCATGTCAGTCAAGTTGGAGTCGTGCTCGCCCCGGCG
CAACTCGAGGACGCAGAACGGATCGGCGCTGAGCGTATACAGGAAGTGCTGACAGAACTCCGGCGTCGTGCTGACTTCGT
CATCGTCGACACACGTGGTGGGTATGATGACATCACGCTGGCTTGTGCGGATGTCGCCTCGACGTTGATTTGGATTTTGA
CGCTCGAAATGACGGCCATCAAAGAGACCAAACGGTTCCTGGAACTCGTCGAGCGACTCGGGTTCCAGCAGAAGCGGATC
ATGTTCGTCTTGAATCAGCAGCGCTCCGGAAGCGGACTGACTGTGGAGGAGGTAGAAGCGAGTCTCCGCTTGTCCATTCC
GATCCGCATCTCGTCTGATCCTCAGGCGGTGATCGCGAGCATCAACGAGGGCACGCCGCTCGCCTGGCAGCACCGACAGC
ATCGCATCACGGCTGAGTTGATACAGTTGGCAGAACTCCTGGCGAACGAGTCGCGAGAAGCCGTGCTGCACGCAAGGGTT
CGCAAACGTCGCCTGCCTTTCTTGAGCGTCTCTCACCGATGGACCAACGGGAGGAGATGA

Upstream 100 bases:

>100_bases
CGGACGGGGTGACCTACGATCGCCTGGTCGAGCGGTATGGACTGCCAGTTCCAGGGACGGTGGTGGTCAGCGGGGGGCCG
CGATGACGGGCGAAAGTACT

Downstream 100 bases:

>100_bases
GTGCCATGTCGCTTCTCCGGCGATTGAGTACGGCAGGTGACACTGGTCTGCTCGCAACCGAAGTGCCGGCCGATCGCCCA
GACGAGCCAGAGCAGTCACG

Product: putative two-component response regulator

Products: NA

Alternate protein names: Cell division inhibitor minD [H]

Number of amino acids: Translated: 419; Mature: 419

Protein sequence:

>419_residues
MRIVIVDDIPESRDNLERLLFFEPDFQVVGKAARGEEAIDLVLRLAPHVVLLDQTLPDLDGIEVASAITARAPGIGVILL
GVEQDPEILRRAMLAGAREYLSKPFSYDDLIEAVRRVGHVANPQSMMPAPATVFAAPLAPVHEPVTRREGQVVVVLGSKG
GVGRTFIATNLAICLQRALQREVVLVDADLMRGDVAVLLNLPAHRSWTDLARLAGPLDGELIHEFVTRHVSQVGVVLAPA
QLEDAERIGAERIQEVLTELRRRADFVIVDTRGGYDDITLACADVASTLIWILTLEMTAIKETKRFLELVERLGFQQKRI
MFVLNQQRSGSGLTVEEVEASLRLSIPIRISSDPQAVIASINEGTPLAWQHRQHRITAELIQLAELLANESREAVLHARV
RKRRLPFLSVSHRWTNGRR

Sequences:

>Translated_419_residues
MRIVIVDDIPESRDNLERLLFFEPDFQVVGKAARGEEAIDLVLRLAPHVVLLDQTLPDLDGIEVASAITARAPGIGVILL
GVEQDPEILRRAMLAGAREYLSKPFSYDDLIEAVRRVGHVANPQSMMPAPATVFAAPLAPVHEPVTRREGQVVVVLGSKG
GVGRTFIATNLAICLQRALQREVVLVDADLMRGDVAVLLNLPAHRSWTDLARLAGPLDGELIHEFVTRHVSQVGVVLAPA
QLEDAERIGAERIQEVLTELRRRADFVIVDTRGGYDDITLACADVASTLIWILTLEMTAIKETKRFLELVERLGFQQKRI
MFVLNQQRSGSGLTVEEVEASLRLSIPIRISSDPQAVIASINEGTPLAWQHRQHRITAELIQLAELLANESREAVLHARV
RKRRLPFLSVSHRWTNGRR
>Mature_419_residues
MRIVIVDDIPESRDNLERLLFFEPDFQVVGKAARGEEAIDLVLRLAPHVVLLDQTLPDLDGIEVASAITARAPGIGVILL
GVEQDPEILRRAMLAGAREYLSKPFSYDDLIEAVRRVGHVANPQSMMPAPATVFAAPLAPVHEPVTRREGQVVVVLGSKG
GVGRTFIATNLAICLQRALQREVVLVDADLMRGDVAVLLNLPAHRSWTDLARLAGPLDGELIHEFVTRHVSQVGVVLAPA
QLEDAERIGAERIQEVLTELRRRADFVIVDTRGGYDDITLACADVASTLIWILTLEMTAIKETKRFLELVERLGFQQKRI
MFVLNQQRSGSGLTVEEVEASLRLSIPIRISSDPQAVIASINEGTPLAWQHRQHRITAELIQLAELLANESREAVLHARV
RKRRLPFLSVSHRWTNGRR

Specific function: ATPase required for the correct placement of the division site. Cell division inhibitors minC and minD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to desta

COG id: COG2894

COG function: function code D; Septum formation inhibitor-activating ATPase

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the parA family. MinD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790102, Length=150, Percent_Identity=33.3333333333333, Blast_Score=71, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002586
- InterPro:   IPR010223 [H]

Pfam domain/function: PF01656 CbiA [H]

EC number: NA

Molecular weight: Translated: 46470; Mature: 46470

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIVIVDDIPESRDNLERLLFFEPDFQVVGKAARGEEAIDLVLRLAPHVVLLDQTLPDLD
CEEEEEECCCCCHHHHHEEEEECCCHHHHCCCCCCHHHHHHHHHHCCCEEEEECCCCCCC
GIEVASAITARAPGIGVILLGVEQDPEILRRAMLAGAREYLSKPFSYDDLIEAVRRVGHV
CHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCC
ANPQSMMPAPATVFAAPLAPVHEPVTRREGQVVVVLGSKGGVGRTFIATNLAICLQRALQ
CCCHHCCCCCHHHHCCCCCCCCCCHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHC
REVVLVDADLMRGDVAVLLNLPAHRSWTDLARLAGPLDGELIHEFVTRHVSQVGVVLAPA
CCEEEEEHHHHCCCEEEEEECCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHCCEEEECH
QLEDAERIGAERIQEVLTELRRRADFVIVDTRGGYDDITLACADVASTLIWILTLEMTAI
HHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
KETKRFLELVERLGFQQKRIMFVLNQQRSGSGLTVEEVEASLRLSIPIRISSDPQAVIAS
HHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCHHHHHCEEEEEEEEEECCCCHHEEEE
INEGTPLAWQHRQHRITAELIQLAELLANESREAVLHARVRKRRLPFLSVSHRWTNGRR
CCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCEEEEECCCCCCCC
>Mature Secondary Structure
MRIVIVDDIPESRDNLERLLFFEPDFQVVGKAARGEEAIDLVLRLAPHVVLLDQTLPDLD
CEEEEEECCCCCHHHHHEEEEECCCHHHHCCCCCCHHHHHHHHHHCCCEEEEECCCCCCC
GIEVASAITARAPGIGVILLGVEQDPEILRRAMLAGAREYLSKPFSYDDLIEAVRRVGHV
CHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCC
ANPQSMMPAPATVFAAPLAPVHEPVTRREGQVVVVLGSKGGVGRTFIATNLAICLQRALQ
CCCHHCCCCCHHHHCCCCCCCCCCHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHC
REVVLVDADLMRGDVAVLLNLPAHRSWTDLARLAGPLDGELIHEFVTRHVSQVGVVLAPA
CCEEEEEHHHHCCCEEEEEECCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHCCEEEECH
QLEDAERIGAERIQEVLTELRRRADFVIVDTRGGYDDITLACADVASTLIWILTLEMTAI
HHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
KETKRFLELVERLGFQQKRIMFVLNQQRSGSGLTVEEVEASLRLSIPIRISSDPQAVIAS
HHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCHHHHHCEEEEEEEEEECCCCHHEEEE
INEGTPLAWQHRQHRITAELIQLAELLANESREAVLHARVRKRRLPFLSVSHRWTNGRR
CCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]