| Definition | Thermomicrobium roseum DSM 5159 chromosome, complete genome. |
|---|---|
| Accession | NC_011959 |
| Length | 2,003,006 |
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The map label for this gene is rpoA [H]
Identifier: 221632951
GI number: 221632951
Start: 930929
End: 931909
Strand: Reverse
Name: rpoA [H]
Synonym: trd_0957
Alternate gene names: 221632951
Gene position: 931909-930929 (Counterclockwise)
Preceding gene: 221632952
Following gene: 221632950
Centisome position: 46.53
GC content: 63.2
Gene sequence:
>981_bases GTGCTCGACTTTGCGCGACCGCGAGTCATTCAAACCCACGCCGGACCGACCTACGGACGGTTCGTCGTCGAGCCGTTGGA ACCCGGTTATGGGACGACGCTCGGCAATGCGCTCCGGCGCATTCTGTTGCGCTCCTTGCCGGGGGCGGCGATTACACGTA TCCGTATCGCTGGCGTGTGGCATGAATTTTCGACGATCGAAGGGGTCCGGGAGGACGTCACGGAGATCGTGCTCAATCTC AAGGGTGTGCGCCTGCGAGCGGTTACTGAGTTCCGCGAGACACGCGCGACCCTCTTCGCCCAGGGTGAGGGCGTCGTGCG AGCAGGTGATGTGGACTGGCCAGCTGAGGTCGAGGTGGTGAATCCTGATCATGTCATCGCCACCCTCGACAACGATCAGG CGCGCCTGGAAATGGATCTCTGGATCGGGCGTGGCCGCGGTTACCTGCCAGCAGAGGCGCAGGAGATTCGCTCGATCGGT GAAATACCGATCGATGCCATCTTCACGCCTACCCTCAAGGTGAACTACGTCGTGGAGCACACGCGGGTCGGGGGCGCGAC GGATTACGACCGGCTGATCCTGGAGATCGTCACCGACGGAACAGTCGAGCCAGCGAAAGCGCTGGTGGAGGCTGCCCGCA TTCTCGTCCAGCATGCTCGATGGATCGCTGAGTTCGAAAGCGAGGGCGCTGAGGAACCGGTGGAGGAATGGAGCGTCGCG CACGTCGACGATACGCGACTCCTCTCGGAGATCGGGCTATCCCAACGCGTACTCAATGCCCTTCGTGCACGGGGCATCGA GCGGGTGGGCCAAGTCCTGGCGATGCGACCCGACCAGCTCCTCGGAATCAGGAACTTCGGTCCGCGTGCGCTTCAGGAAC TCCGGGAACGCTTGCAGGAGAACGGCTACACCGAGGGGCCGCTTTTCTCCGGTGCGGTCCCCGAGGTCGGGGTCGGTGCT GGAGAAGGTGAGGAGGACTGA
Upstream 100 bases:
>100_bases GACGAGATCGATATCCCGCCGGTGAACACGCAGCTCGTCGTCGAATACTACAGCCGGCGCTGAACGTTAGAGAAATCGGA CGCTCGGGGAGGCGAGATTC
Downstream 100 bases:
>100_bases GCGTGCGTCATCGGAAAGCAGGGCGGAAGTTCGGGCGCCGAACCAATCCGCGGAAAAACCTTTTCCGGAATCTGGCGGTA TCCTTGATCCTTCATGAACG
Product: DNA-directed RNA polymerase subunit alpha
Products: NA
Alternate protein names: RNAP subunit alpha; RNA polymerase subunit alpha; Transcriptase subunit alpha [H]
Number of amino acids: Translated: 326; Mature: 326
Protein sequence:
>326_residues MLDFARPRVIQTHAGPTYGRFVVEPLEPGYGTTLGNALRRILLRSLPGAAITRIRIAGVWHEFSTIEGVREDVTEIVLNL KGVRLRAVTEFRETRATLFAQGEGVVRAGDVDWPAEVEVVNPDHVIATLDNDQARLEMDLWIGRGRGYLPAEAQEIRSIG EIPIDAIFTPTLKVNYVVEHTRVGGATDYDRLILEIVTDGTVEPAKALVEAARILVQHARWIAEFESEGAEEPVEEWSVA HVDDTRLLSEIGLSQRVLNALRARGIERVGQVLAMRPDQLLGIRNFGPRALQELRERLQENGYTEGPLFSGAVPEVGVGA GEGEED
Sequences:
>Translated_326_residues MLDFARPRVIQTHAGPTYGRFVVEPLEPGYGTTLGNALRRILLRSLPGAAITRIRIAGVWHEFSTIEGVREDVTEIVLNL KGVRLRAVTEFRETRATLFAQGEGVVRAGDVDWPAEVEVVNPDHVIATLDNDQARLEMDLWIGRGRGYLPAEAQEIRSIG EIPIDAIFTPTLKVNYVVEHTRVGGATDYDRLILEIVTDGTVEPAKALVEAARILVQHARWIAEFESEGAEEPVEEWSVA HVDDTRLLSEIGLSQRVLNALRARGIERVGQVLAMRPDQLLGIRNFGPRALQELRERLQENGYTEGPLFSGAVPEVGVGA GEGEED >Mature_326_residues MLDFARPRVIQTHAGPTYGRFVVEPLEPGYGTTLGNALRRILLRSLPGAAITRIRIAGVWHEFSTIEGVREDVTEIVLNL KGVRLRAVTEFRETRATLFAQGEGVVRAGDVDWPAEVEVVNPDHVIATLDNDQARLEMDLWIGRGRGYLPAEAQEIRSIG EIPIDAIFTPTLKVNYVVEHTRVGGATDYDRLILEIVTDGTVEPAKALVEAARILVQHARWIAEFESEGAEEPVEEWSVA HVDDTRLLSEIGLSQRVLNALRARGIERVGQVLAMRPDQLLGIRNFGPRALQELRERLQENGYTEGPLFSGAVPEVGVGA GEGEED
Specific function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates [H]
COG id: COG0202
COG function: function code K; DNA-directed RNA polymerase, alpha subunit/40 kD subunit
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the RNA polymerase alpha chain family [H]
Homologues:
Organism=Escherichia coli, GI1789690, Length=310, Percent_Identity=37.741935483871, Blast_Score=202, Evalue=3e-53,
Paralogues:
None
Copy number: 850 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 560 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). 6847 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 7,000 Molecules/Cell In: Glucose minimal media
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR011261 - InterPro: IPR011262 - InterPro: IPR009025 - InterPro: IPR011263 - InterPro: IPR011260 - InterPro: IPR011773 - ProDom: PD001179 [H]
Pfam domain/function: PF01000 RNA_pol_A_bac; PF03118 RNA_pol_A_CTD; PF01193 RNA_pol_L [H]
EC number: =2.7.7.6 [H]
Molecular weight: Translated: 36005; Mature: 36005
Theoretical pI: Translated: 4.62; Mature: 4.62
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.0 %Cys (Translated Protein) 0.9 %Met (Translated Protein) 0.9 %Cys+Met (Translated Protein) 0.0 %Cys (Mature Protein) 0.9 %Met (Mature Protein) 0.9 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MLDFARPRVIQTHAGPTYGRFVVEPLEPGYGTTLGNALRRILLRSLPGAAITRIRIAGVW CCCCCCCCEEEECCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCHHHHEEEEEHHH HEFSTIEGVREDVTEIVLNLKGVRLRAVTEFRETRATLFAQGEGVVRAGDVDWPAEVEVV HHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHEEECCCCEEEECCCCCCCEEEEE NPDHVIATLDNDQARLEMDLWIGRGRGYLPAEAQEIRSIGEIPIDAIFTPTLKVNYVVEH CCCEEEEEECCCCCEEEEEEEEECCCCCCCCCHHHHHHHCCCCCCCEECCCEEEEEEEEE TRVGGATDYDRLILEIVTDGTVEPAKALVEAARILVQHARWIAEFESEGAEEPVEEWSVA CCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCEE HVDDTRLLSEIGLSQRVLNALRARGIERVGQVLAMRPDQLLGIRNFGPRALQELRERLQE CCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCHHHHHHHHHHHHH NGYTEGPLFSGAVPEVGVGAGEGEED CCCCCCCCCCCCCCCCCCCCCCCCCC >Mature Secondary Structure MLDFARPRVIQTHAGPTYGRFVVEPLEPGYGTTLGNALRRILLRSLPGAAITRIRIAGVW CCCCCCCCEEEECCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCHHHHEEEEEHHH HEFSTIEGVREDVTEIVLNLKGVRLRAVTEFRETRATLFAQGEGVVRAGDVDWPAEVEVV HHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHEEECCCCEEEECCCCCCCEEEEE NPDHVIATLDNDQARLEMDLWIGRGRGYLPAEAQEIRSIGEIPIDAIFTPTLKVNYVVEH CCCEEEEEECCCCCEEEEEEEEECCCCCCCCCHHHHHHHCCCCCCCEECCCEEEEEEEEE TRVGGATDYDRLILEIVTDGTVEPAKALVEAARILVQHARWIAEFESEGAEEPVEEWSVA CCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCEE HVDDTRLLSEIGLSQRVLNALRARGIERVGQVLAMRPDQLLGIRNFGPRALQELRERLQE CCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCHHHHHHHHHHHHH NGYTEGPLFSGAVPEVGVGAGEGEED CCCCCCCCCCCCCCCCCCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: NA