Click here to switch to the map view.

The map label for this gene is fabZ

Identifier: 221632678

GI number: 221632678

Start: 656423

End: 656872

Strand: Reverse

Name: fabZ

Synonym: trd_0661

Alternate gene names: 221632678

Gene position: 656872-656423 (Counterclockwise)

Preceding gene: 221632679

Following gene: 221632677

Centisome position: 32.79

GC content: 58.67

Gene sequence:

>450_bases
ATGTTGGAAGCCTGGCAAATTCAGGAGATCATTCCTCACCGCTATCCCTTTCTCCTGGTCGATCGCATCATCGAGATCGA
ATGGGGGCAACGCGCCGTCGGCATCAAAAATGTGACGGTCAACGAGCCGTTCTTCGTCGGTCACTTTCCCGGAAATCCGG
TGATGCCTGGTGTACTCATCATCGAAGCACTGGCCCAGGTCGGTGCCGTTGCTCTCCTCGGCCACCCGCAGTATCGGGAC
AAAACAGCCTTCTTCGCTGGCATCGATGGGGTGCGTTTCAAGCGGCCAGTTCGCCCCGGCGATACCTTGCGGCTCGAAGT
TCAAATCGGTAAGGTCCGTCGCAATATCGGAACTGGTACCGGCCGAGCCACCGTCGACGGAGAACTCGCCGCTGAAGGGG
AGATCCTCTTCGCTCTCTTGGACCCGGAAGCTGCGCGTACGACACGCTGA

Upstream 100 bases:

>100_bases
TCGGTGTACCCATCACGATGATCGGCGTCGGACCAGCCCGTCGTCAGATTCTCTGGCGACCAGCCGGTGCCCTGACGTGA
TCGAGACCGAGGAGACCAGC

Downstream 100 bases:

>100_bases
CCAATGCGCCACGTTCTCGTCGTCAAACCCTGCTGCTTGGGCGATGCGCTGATGGCGACCCCTGTCCTCCGAGCGCTCCG
TACGACGTACCCCGACATGA

Product: beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ

Products: NA

Alternate protein names: (3R)-hydroxymyristoyl ACP dehydrase

Number of amino acids: Translated: 149; Mature: 149

Protein sequence:

>149_residues
MLEAWQIQEIIPHRYPFLLVDRIIEIEWGQRAVGIKNVTVNEPFFVGHFPGNPVMPGVLIIEALAQVGAVALLGHPQYRD
KTAFFAGIDGVRFKRPVRPGDTLRLEVQIGKVRRNIGTGTGRATVDGELAAEGEILFALLDPEAARTTR

Sequences:

>Translated_149_residues
MLEAWQIQEIIPHRYPFLLVDRIIEIEWGQRAVGIKNVTVNEPFFVGHFPGNPVMPGVLIIEALAQVGAVALLGHPQYRD
KTAFFAGIDGVRFKRPVRPGDTLRLEVQIGKVRRNIGTGTGRATVDGELAAEGEILFALLDPEAARTTR
>Mature_149_residues
MLEAWQIQEIIPHRYPFLLVDRIIEIEWGQRAVGIKNVTVNEPFFVGHFPGNPVMPGVLIIEALAQVGAVALLGHPQYRD
KTAFFAGIDGVRFKRPVRPGDTLRLEVQIGKVRRNIGTGTGRATVDGELAAEGEILFALLDPEAARTTR

Specific function: Involved in saturated fatty acids biosynthesis

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabZ subfamily

Homologues:

Organism=Escherichia coli, GI1786377, Length=139, Percent_Identity=46.7625899280576, Blast_Score=131, Evalue=2e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FABZ_THERP (B9KYV7)

Other databases:

- EMBL:   CP001275
- RefSeq:   YP_002521899.1
- ProteinModelPortal:   B9KYV7
- GeneID:   7355367
- GenomeReviews:   CP001275_GR
- KEGG:   tro:trd_0661
- OMA:   KERRGVA
- ProtClustDB:   CLSK2807622
- GO:   GO:0005737
- HAMAP:   MF_00406
- InterPro:   IPR013114
- InterPro:   IPR010084
- TIGRFAMs:   TIGR01750

Pfam domain/function: PF07977 FabA

EC number: 4.2.1.-

Molecular weight: Translated: 16465; Mature: 16465

Theoretical pI: Translated: 7.79; Mature: 7.79

Prosite motif: NA

Important sites: ACT_SITE 48-48

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEAWQIQEIIPHRYPFLLVDRIIEIEWGQRAVGIKNVTVNEPFFVGHFPGNPVMPGVLI
CCCCCCHHHHCCCCCCHHEEHEEEEECCCCEECCEEEEEECCCEEEEECCCCCCCCHHHH
IEALAQVGAVALLGHPQYRDKTAFFAGIDGVRFKRPVRPGDTLRLEVQIGKVRRNIGTGT
HHHHHHHCEEEEECCCCCCCCEEEEECCCCCEEECCCCCCCEEEEEEEEEEHHHHCCCCC
GRATVDGELAAEGEILFALLDPEAARTTR
CCEEECCCEECCCCEEEEEECCCCCCCCC
>Mature Secondary Structure
MLEAWQIQEIIPHRYPFLLVDRIIEIEWGQRAVGIKNVTVNEPFFVGHFPGNPVMPGVLI
CCCCCCHHHHCCCCCCHHEEHEEEEECCCCEECCEEEEEECCCEEEEECCCCCCCCHHHH
IEALAQVGAVALLGHPQYRDKTAFFAGIDGVRFKRPVRPGDTLRLEVQIGKVRRNIGTGT
HHHHHHHCEEEEECCCCCCCCEEEEECCCCCEEECCCCCCCEEEEEEEEEEHHHHCCCCC
GRATVDGELAAEGEILFALLDPEAARTTR
CCEEECCCEECCCCEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Carbon-Oxygen Lyases; Hydro-Lyases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA