| Definition | Thermomicrobium roseum DSM 5159 chromosome, complete genome. |
|---|---|
| Accession | NC_011959 |
| Length | 2,003,006 |
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The map label for this gene is hisS [H]
Identifier: 221632656
GI number: 221632656
Start: 627521
End: 628963
Strand: Reverse
Name: hisS [H]
Synonym: trd_0639
Alternate gene names: 221632656
Gene position: 628963-627521 (Counterclockwise)
Preceding gene: 221632657
Following gene: 221632655
Centisome position: 31.4
GC content: 62.72
Gene sequence:
>1443_bases GTGACCATTTACCAGCTCACCGAACCACCGCAACCCTTAGAACGCTTGCGCGGCATGCAAGACACCCCCCCTGCTCTTCA TCGGCGGCGACAAGCGGTTTTGCACCGTATCGCTCGTGTGCTCGAGCGTCACGGATACGAATTCATCGAAACACCGATCT TGGAATCCACCGAACTCTTCCTTCGCAAGTCCGGTCCTGAACGGATCGCTCAGCTCTACGCCTTCAGCTTCCGGAATCGC GATATCGCCCTCCGTCCCGAGCACACGGCATCGATCCTTCGCTACTACGTGGAGTCGAGACAGAACGATCCCTTACCGCT GCGCTTCGCGTATGCGGGTCCTGTTTTCCGCTATGAGCGACCGCAAGCTGGGCGCACACGCCAATTCACCGAGATCGGGG GTGAACTGCTGGGTGCTCCGGGGCCGAGCGGGGACGCTGAGGTCATCCACCTCGCTGCTGAGATTCTCGAAGCAGTCGGG ATCATGCCCCGTATCGTCATCGGGCACGTCGGTATCGTGCTGGACTATCTCGCTCATCTGCCCCTCCGGCAACGTGCGCG CGATTGGCTTCTTTGGAGCATGGAGCGACTGCGCAAGGGGCAAACGATCGACATCGAGAGCGAACTCCCGGCATTCGTCG ATTCCACCGATATCGTGCAGATCACCCAGGAAGTGCGGACAAAACTCGCCTTGACCACGGAGGACCTGGAACGGTTGATT CTCGCACTGCTGCGAGAAGTCGGCGTGCCGATGACCGGTGCATCCCGCCAGCCCGAGGAGATCGTTCGCGGTGTCCTGGC AAAGCTCCAACGCAGCGCCGATCCTGACGCGTTGCGGCAAGCACTCGCTTTCGCCCGCGAACTGGCGTCCCTCTCGGGTC CGCCGGACGACGTACTCTCCGCGCTCCGCCGGATCGTCGAGCGCTACGGACTCAGTCCCGCACCACTGCAGCAAATCGAC GAGGTGCTCGATCAGCTCGCCGCCTATGGACTGGAGACCGATCGGATCGTGCTCGCGCCAGGAATGGCACGCGGACTGCA CTACTACACGGGCATCCTCTTCGAGATGTATTCCCAAACTGACGAGGGACTGCAACTGTGCGGCGGCGGCCGGTACGACG ATCTCGCTCAGCTGCTCGGTGCCCGCCAGCCGCTCCCAGCGTGCGGCTTCGCCGGTGGCCTCGAACGGATCGCCGATGCT TCAGCCTTGCAGCCGAAGACCGAGCCACGCCTCCTCGTCACCGCGGCCGATCGCTCCGCCATTACAGCCGCCACGCGTTT CGCCGAGCAGCTACGAGCCAGCGGCGCGATCGTCGAACTGGACGTCCGTCAGCGGTCACTTTCTTCCAACCGTCGTTACG CCCGTCGGCGCGGCGTCACTGAAATCCTGATCGTCGACGCGACGGGTTCCGTTCGCCGTATCGATCTCTCCACCGAGGAA TGA
Upstream 100 bases:
>100_bases TCTCGGCTCCCGACCGCCCATTGAGCGAGGAGGAACTGCAGCGCCTGCGCGAACGGATCGAGCAACAGGTCCGTCGACGG GTCAAGGGAGAGTTCCGCCG
Downstream 100 bases:
>100_bases CCTGATGGCCGAACCGCTCCGAATCGCCATCGCTTCCAAAGGAGAATACGAGCAAGCAACCTTGCGTTTCCTCGAGAGTG CTGGCCTCAGCGTGTGGCGG
Product: histidyl-tRNA synthetase
Products: NA
Alternate protein names: Histidine--tRNA ligase; HisRS [H]
Number of amino acids: Translated: 480; Mature: 479
Protein sequence:
>480_residues MTIYQLTEPPQPLERLRGMQDTPPALHRRRQAVLHRIARVLERHGYEFIETPILESTELFLRKSGPERIAQLYAFSFRNR DIALRPEHTASILRYYVESRQNDPLPLRFAYAGPVFRYERPQAGRTRQFTEIGGELLGAPGPSGDAEVIHLAAEILEAVG IMPRIVIGHVGIVLDYLAHLPLRQRARDWLLWSMERLRKGQTIDIESELPAFVDSTDIVQITQEVRTKLALTTEDLERLI LALLREVGVPMTGASRQPEEIVRGVLAKLQRSADPDALRQALAFARELASLSGPPDDVLSALRRIVERYGLSPAPLQQID EVLDQLAAYGLETDRIVLAPGMARGLHYYTGILFEMYSQTDEGLQLCGGGRYDDLAQLLGARQPLPACGFAGGLERIADA SALQPKTEPRLLVTAADRSAITAATRFAEQLRASGAIVELDVRQRSLSSNRRYARRRGVTEILIVDATGSVRRIDLSTEE
Sequences:
>Translated_480_residues MTIYQLTEPPQPLERLRGMQDTPPALHRRRQAVLHRIARVLERHGYEFIETPILESTELFLRKSGPERIAQLYAFSFRNR DIALRPEHTASILRYYVESRQNDPLPLRFAYAGPVFRYERPQAGRTRQFTEIGGELLGAPGPSGDAEVIHLAAEILEAVG IMPRIVIGHVGIVLDYLAHLPLRQRARDWLLWSMERLRKGQTIDIESELPAFVDSTDIVQITQEVRTKLALTTEDLERLI LALLREVGVPMTGASRQPEEIVRGVLAKLQRSADPDALRQALAFARELASLSGPPDDVLSALRRIVERYGLSPAPLQQID EVLDQLAAYGLETDRIVLAPGMARGLHYYTGILFEMYSQTDEGLQLCGGGRYDDLAQLLGARQPLPACGFAGGLERIADA SALQPKTEPRLLVTAADRSAITAATRFAEQLRASGAIVELDVRQRSLSSNRRYARRRGVTEILIVDATGSVRRIDLSTEE >Mature_479_residues TIYQLTEPPQPLERLRGMQDTPPALHRRRQAVLHRIARVLERHGYEFIETPILESTELFLRKSGPERIAQLYAFSFRNRD IALRPEHTASILRYYVESRQNDPLPLRFAYAGPVFRYERPQAGRTRQFTEIGGELLGAPGPSGDAEVIHLAAEILEAVGI MPRIVIGHVGIVLDYLAHLPLRQRARDWLLWSMERLRKGQTIDIESELPAFVDSTDIVQITQEVRTKLALTTEDLERLIL ALLREVGVPMTGASRQPEEIVRGVLAKLQRSADPDALRQALAFARELASLSGPPDDVLSALRRIVERYGLSPAPLQQIDE VLDQLAAYGLETDRIVLAPGMARGLHYYTGILFEMYSQTDEGLQLCGGGRYDDLAQLLGARQPLPACGFAGGLERIADAS ALQPKTEPRLLVTAADRSAITAATRFAEQLRASGAIVELDVRQRSLSSNRRYARRRGVTEILIVDATGSVRRIDLSTEE
Specific function: Unknown
COG id: COG0124
COG function: function code J; Histidyl-tRNA synthetase
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family [H]
Homologues:
Organism=Escherichia coli, GI1788861, Length=193, Percent_Identity=36.2694300518135, Blast_Score=103, Evalue=2e-23,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002314 - InterPro: IPR006195 - InterPro: IPR004154 - InterPro: IPR015807 - InterPro: IPR004516 [H]
Pfam domain/function: PF03129 HGTP_anticodon; PF00587 tRNA-synt_2b [H]
EC number: =6.1.1.21 [H]
Molecular weight: Translated: 53600; Mature: 53469
Theoretical pI: Translated: 6.74; Mature: 6.74
Prosite motif: PS50862 AA_TRNA_LIGASE_II
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.4 %Cys (Translated Protein) 1.5 %Met (Translated Protein) 1.9 %Cys+Met (Translated Protein) 0.4 %Cys (Mature Protein) 1.3 %Met (Mature Protein) 1.7 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MTIYQLTEPPQPLERLRGMQDTPPALHRRRQAVLHRIARVLERHGYEFIETPILESTELF CEEECCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHH LRKSGPERIAQLYAFSFRNRDIALRPEHTASILRYYVESRQNDPLPLRFAYAGPVFRYER HHCCCHHHHHHHHHHHHCCCCEEECCHHHHHHHHHHHHHCCCCCCCEEEEECCCEEEECC PQAGRTRQFTEIGGELLGAPGPSGDAEVIHLAAEILEAVGIMPRIVIGHVGIVLDYLAHL CCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCC PLRQRARDWLLWSMERLRKGQTIDIESELPAFVDSTDIVQITQEVRTKLALTTEDLERLI CHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH LALLREVGVPMTGASRQPEEIVRGVLAKLQRSADPDALRQALAFARELASLSGPPDDVLS HHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHH ALRRIVERYGLSPAPLQQIDEVLDQLAAYGLETDRIVLAPGMARGLHYYTGILFEMYSQT HHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCEEECCCHHHHHHHHHHHHHHHHHCC DEGLQLCGGGRYDDLAQLLGARQPLPACGFAGGLERIADASALQPKTEPRLLVTAADRSA HHHHHHCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEECCCHH ITAATRFAEQLRASGAIVELDVRQRSLSSNRRYARRRGVTEILIVDATGSVRRIDLSTEE HHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHCCCEEEEEEECCCCEEEECCCCCC >Mature Secondary Structure TIYQLTEPPQPLERLRGMQDTPPALHRRRQAVLHRIARVLERHGYEFIETPILESTELF EEECCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHH LRKSGPERIAQLYAFSFRNRDIALRPEHTASILRYYVESRQNDPLPLRFAYAGPVFRYER HHCCCHHHHHHHHHHHHCCCCEEECCHHHHHHHHHHHHHCCCCCCCEEEEECCCEEEECC PQAGRTRQFTEIGGELLGAPGPSGDAEVIHLAAEILEAVGIMPRIVIGHVGIVLDYLAHL CCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCC PLRQRARDWLLWSMERLRKGQTIDIESELPAFVDSTDIVQITQEVRTKLALTTEDLERLI CHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH LALLREVGVPMTGASRQPEEIVRGVLAKLQRSADPDALRQALAFARELASLSGPPDDVLS HHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHH ALRRIVERYGLSPAPLQQIDEVLDQLAAYGLETDRIVLAPGMARGLHYYTGILFEMYSQT HHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCEEECCCHHHHHHHHHHHHHHHHHCC DEGLQLCGGGRYDDLAQLLGARQPLPACGFAGGLERIADASALQPKTEPRLLVTAADRSA HHHHHHCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEECCCHH ITAATRFAEQLRASGAIVELDVRQRSLSSNRRYARRRGVTEILIVDATGSVRRIDLSTEE HHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHCCCEEEEEEECCCCEEEECCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 8688087 [H]