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The map label for this gene is ftsK [H]

Identifier: 221632239

GI number: 221632239

Start: 210497

End: 212734

Strand: Reverse

Name: ftsK [H]

Synonym: trd_0205

Alternate gene names: 221632239

Gene position: 212734-210497 (Counterclockwise)

Preceding gene: 221632240

Following gene: 221632238

Centisome position: 10.62

GC content: 66.35

Gene sequence:

>2238_bases
ATGGCGCGGAAGCGAGCAAAAGAACGGAGAACCAGAGGGGAGACAGCACCGCTCGCCGCCGGTTCCCAAAGACGCCGCCT
GCGCGCGATCGTCACCCGGCTGGCACAGGTGGCAGCACTCGTTCCGCGCCGCCTGCCGCGTGACCTCGCTGGGCTGTTTC
TCGCCACGGTCGGCGTGCTCCTGACCCTGGCGCTTTTCGGCCACGAGCGCGAGACTGGGCTTGCCGGCTGGTTCGCCCAG
ACCTGCCGGCAACTCTTCGGCCGCGGTGCGATCGTGGTGCCGCTCGCCTGCTGGTGGGGTGCCCTCGAACTCGTTGCCTC
CCGCTCGCGAGCCGGCACGGTCCGCCGGGCCGTGGGGCTCGCACTGTATGGTTCCGCAGCCGTCGCCCTGCTCGACGCTC
GCCCGGCTGACCAGGTCGAGGAGGCTGGAGGTTACATCGGTGCCGGCGTGGCAGCACTCCTCCGGCTCATCGGGGGTGAC
CTCGGTCTTGGGCTCCTCGCTCTGGCCCTCGGCCTGGCCGGCTCGACGCTCGTCGCTGGTATCGAGCTCGGCACGCTCGC
GCGAACGATCCTCACGGCGGCGCGACGAACCGGGCAGATCGTCCGGCGGAGATCGTCCGCTCGCGCGGTCGACCTCCCCG
CGTCTCCAGCGCCAGCGGAGTCCGGCCGCTCGGACGAGACCGTCCAGCGCGAAACGACGCGACCGGTCATCGCGACACGC
CACACACCAGCGAGCCGTTCGCGTGGGCGCCGAACGCCCGTTTCCCCTCAGCAGCGTGTCCAAGAGCGCCCGTCCGGTGA
GCCGGAACCGGTCGCAGCGAACGCGGCCACGCCGGCTGCTGCAGGGGATCAGGTGCTTCCCGAGATCAGCCGCTTGCAGC
GGTACGAGGCGAGCTTGCCCGATGCGGAAGAACTGGAGCGCAAGGCCGCGATCATCCAGGAGACGCTGGCAAACTTCCGA
GTAGACGCTCGTGTCCGCGAAATCTATCCCGGTCCTGCCGTGACGTTGTTCACCCTGGAACCCGGTCCCGGCGTCAAGGT
GCGGCGCATCACCGAGCTTCAGAACGATCTGGCATTAGCGCTGGCTGCGCCAGCGATCCGGATCGAGGCACCGGTTCCCG
GTATGGCACGCGTGGGCATCGAGGTCCCGAATAGCGCGATTTCCACGGTAGGCCTGCGTGAGGTACTGGAATCGGCGACC
TTCCAGCGCTCTCGAGCACGCCTCCCGCTGGCTCTCGGGCGGGACGTGCACGGCGAGTATGTCGTCGCTGACCTGACTCG
CATGCCGCATCTCCTCATCGCTGGCGCGACCGGATCCGGCAAATCGGTGTGCATCAACGGCATCATCGCCACCTTTCTGC
TCACGCGCCGGCCGGACGAACTCCAGATGCTGTTGATCGATCCGAAGAAGGTCGAACTCGCTGGTTACGATGGAGTGCCG
CACCTCAAGCGCCCAGTCGTGACCGATATGGGACTCGTCGTCGGTGCGCTGCGACGCGTCCTGCAGGAAATGGAGCGACG
CTACGAGCTTTTCGCCCAACTGGGAGTGCGCAATCTCGAAGGTTATCGCCTGCGACGCGAGGAAGACCCATCGCTCGAGC
CCTTGCCCTATCTCGTCGTCATCATCGATGAGCTGGCTGATCTCATGCTGACGACACCGGACGAGGTCGAGACACTCCTG
GTGCGACTGGCCCAGATGGCTCGTGCCACTGGGATTCACCTCCTGATCGCGACACAGCGGCCCTCAGTCGACGTCCTCAC
CGGGCTGATCAAGGCCAATGTGCCGGCGCGGATCGCCTTCGCTGTCACCTCGCAGACCGATAGCCGGGTGATCCTCGATA
TGCCCGGGGCCGAACGCTTGCTCGGGCGCGGCGACATGCTCTATCTTCCGCCCGACGCGGCACGTCCCTTGCGCGTACAA
GGTTCGTTCATCGACGACCGCGACTTGGAATACGTCGTCGAGCACTGGCGGCAACTCTATCCGGTCCCACAATACGACCC
GAGTTGGCTCGATCTCGAGGAAACGATTCAGGAGACGAGTCGAGGCGAGGACCCCTTGCTCGAACAGGCCCGCCAACTCG
TTCGCCAACTCGGGACAGCCTCGACGTCGCTCCTCCAGCGACGACTGCGGATCGGCTACAACCGGGCAGCACGCCTGATG
GAGCAATTGGAAGCTGAAGGAATAGTCGGCCCGGCTGAGGGAGCGCGCGGCCGCGTTGTCTATCTCGGTGACGAGTGA

Upstream 100 bases:

>100_bases
GTAGAGGCGCAGCAAAGCGAGGAAAAGGCACAGCAGATGCGCTTGTTCTGACCCCCTGCTATACTCCGTACGGACACGCG
AACGAACGCAGGGGGACACG

Downstream 100 bases:

>100_bases
TGGGGACGAGTGGAACCGGCCCTTCTGGTATACTCAAACCAGTGAACGCGCGTTTTGCCTGACGGCGACCGAGGTGACAG
TGCGCGCACGTGGGCCAGCC

Product: DNA translocase ftsK

Products: NA

Alternate protein names: DNA translocase SpoIIIE; Stage III sporulation protein E [H]

Number of amino acids: Translated: 745; Mature: 744

Protein sequence:

>745_residues
MARKRAKERRTRGETAPLAAGSQRRRLRAIVTRLAQVAALVPRRLPRDLAGLFLATVGVLLTLALFGHERETGLAGWFAQ
TCRQLFGRGAIVVPLACWWGALELVASRSRAGTVRRAVGLALYGSAAVALLDARPADQVEEAGGYIGAGVAALLRLIGGD
LGLGLLALALGLAGSTLVAGIELGTLARTILTAARRTGQIVRRRSSARAVDLPASPAPAESGRSDETVQRETTRPVIATR
HTPASRSRGRRTPVSPQQRVQERPSGEPEPVAANAATPAAAGDQVLPEISRLQRYEASLPDAEELERKAAIIQETLANFR
VDARVREIYPGPAVTLFTLEPGPGVKVRRITELQNDLALALAAPAIRIEAPVPGMARVGIEVPNSAISTVGLREVLESAT
FQRSRARLPLALGRDVHGEYVVADLTRMPHLLIAGATGSGKSVCINGIIATFLLTRRPDELQMLLIDPKKVELAGYDGVP
HLKRPVVTDMGLVVGALRRVLQEMERRYELFAQLGVRNLEGYRLRREEDPSLEPLPYLVVIIDELADLMLTTPDEVETLL
VRLAQMARATGIHLLIATQRPSVDVLTGLIKANVPARIAFAVTSQTDSRVILDMPGAERLLGRGDMLYLPPDAARPLRVQ
GSFIDDRDLEYVVEHWRQLYPVPQYDPSWLDLEETIQETSRGEDPLLEQARQLVRQLGTASTSLLQRRLRIGYNRAARLM
EQLEAEGIVGPAEGARGRVVYLGDE

Sequences:

>Translated_745_residues
MARKRAKERRTRGETAPLAAGSQRRRLRAIVTRLAQVAALVPRRLPRDLAGLFLATVGVLLTLALFGHERETGLAGWFAQ
TCRQLFGRGAIVVPLACWWGALELVASRSRAGTVRRAVGLALYGSAAVALLDARPADQVEEAGGYIGAGVAALLRLIGGD
LGLGLLALALGLAGSTLVAGIELGTLARTILTAARRTGQIVRRRSSARAVDLPASPAPAESGRSDETVQRETTRPVIATR
HTPASRSRGRRTPVSPQQRVQERPSGEPEPVAANAATPAAAGDQVLPEISRLQRYEASLPDAEELERKAAIIQETLANFR
VDARVREIYPGPAVTLFTLEPGPGVKVRRITELQNDLALALAAPAIRIEAPVPGMARVGIEVPNSAISTVGLREVLESAT
FQRSRARLPLALGRDVHGEYVVADLTRMPHLLIAGATGSGKSVCINGIIATFLLTRRPDELQMLLIDPKKVELAGYDGVP
HLKRPVVTDMGLVVGALRRVLQEMERRYELFAQLGVRNLEGYRLRREEDPSLEPLPYLVVIIDELADLMLTTPDEVETLL
VRLAQMARATGIHLLIATQRPSVDVLTGLIKANVPARIAFAVTSQTDSRVILDMPGAERLLGRGDMLYLPPDAARPLRVQ
GSFIDDRDLEYVVEHWRQLYPVPQYDPSWLDLEETIQETSRGEDPLLEQARQLVRQLGTASTSLLQRRLRIGYNRAARLM
EQLEAEGIVGPAEGARGRVVYLGDE
>Mature_744_residues
ARKRAKERRTRGETAPLAAGSQRRRLRAIVTRLAQVAALVPRRLPRDLAGLFLATVGVLLTLALFGHERETGLAGWFAQT
CRQLFGRGAIVVPLACWWGALELVASRSRAGTVRRAVGLALYGSAAVALLDARPADQVEEAGGYIGAGVAALLRLIGGDL
GLGLLALALGLAGSTLVAGIELGTLARTILTAARRTGQIVRRRSSARAVDLPASPAPAESGRSDETVQRETTRPVIATRH
TPASRSRGRRTPVSPQQRVQERPSGEPEPVAANAATPAAAGDQVLPEISRLQRYEASLPDAEELERKAAIIQETLANFRV
DARVREIYPGPAVTLFTLEPGPGVKVRRITELQNDLALALAAPAIRIEAPVPGMARVGIEVPNSAISTVGLREVLESATF
QRSRARLPLALGRDVHGEYVVADLTRMPHLLIAGATGSGKSVCINGIIATFLLTRRPDELQMLLIDPKKVELAGYDGVPH
LKRPVVTDMGLVVGALRRVLQEMERRYELFAQLGVRNLEGYRLRREEDPSLEPLPYLVVIIDELADLMLTTPDEVETLLV
RLAQMARATGIHLLIATQRPSVDVLTGLIKANVPARIAFAVTSQTDSRVILDMPGAERLLGRGDMLYLPPDAARPLRVQG
SFIDDRDLEYVVEHWRQLYPVPQYDPSWLDLEETIQETSRGEDPLLEQARQLVRQLGTASTSLLQRRLRIGYNRAARLME
QLEAEGIVGPAEGARGRVVYLGDE

Specific function: DNA motor protein, which is both required to move DNA out of the region of the septum during cell division and for the septum formation. Tracks DNA in an ATP-dependent manner by generating positive supercoils in front of it and negative supercoils behind

COG id: COG1674

COG function: function code D; DNA segregation ATPase FtsK/SpoIIIE and related proteins

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein. Note=Located at the septum. The large C-terminal part of the protein is cytoplasmic (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FtsK domain [H]

Homologues:

Organism=Escherichia coli, GI1787117, Length=469, Percent_Identity=47.1215351812367, Blast_Score=403, Evalue=1e-113,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR018541
- InterPro:   IPR002543 [H]

Pfam domain/function: PF09397 Ftsk_gamma; PF01580 FtsK_SpoIIIE [H]

EC number: NA

Molecular weight: Translated: 80979; Mature: 80848

Theoretical pI: Translated: 9.91; Mature: 9.91

Prosite motif: PS50901 FTSK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARKRAKERRTRGETAPLAAGSQRRRLRAIVTRLAQVAALVPRRLPRDLAGLFLATVGVL
CCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
LTLALFGHERETGLAGWFAQTCRQLFGRGAIVVPLACWWGALELVASRSRAGTVRRAVGL
HHHHHHCCCCCCCHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALYGSAAVALLDARPADQVEEAGGYIGAGVAALLRLIGGDLGLGLLALALGLAGSTLVAG
HHHCCHHEEEECCCCHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHH
IELGTLARTILTAARRTGQIVRRRSSARAVDLPASPAPAESGRSDETVQRETTRPVIATR
HHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCHHHHHCCCCEEEEC
HTPASRSRGRRTPVSPQQRVQERPSGEPEPVAANAATPAAAGDQVLPEISRLQRYEASLP
CCCCHHHCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCC
DAEELERKAAIIQETLANFRVDARVREIYPGPAVTLFTLEPGPGVKVRRITELQNDLALA
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCEEHHHHHHHHHHHHH
LAAPAIRIEAPVPGMARVGIEVPNSAISTVGLREVLESATFQRSRARLPLALGRDVHGEY
HCCCCEEEECCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCCCCCE
VVADLTRMPHLLIAGATGSGKSVCINGIIATFLLTRRPDELQMLLIDPKKVELAGYDGVP
EEHHHHHCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCEEEEECCCCCC
HLKRPVVTDMGLVVGALRRVLQEMERRYELFAQLGVRNLEGYRLRREEDPSLEPLPYLVV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHH
IIDELADLMLTTPDEVETLLVRLAQMARATGIHLLIATQRPSVDVLTGLIKANVPARIAF
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCEEEEEEECCCCHHHHHHHHHCCCCCEEEE
AVTSQTDSRVILDMPGAERLLGRGDMLYLPPDAARPLRVQGSFIDDRDLEYVVEHWRQLY
EEECCCCCEEEEECCCHHHHHCCCCEEEECCCCCCCEEEECCCCCCCCHHHHHHHHHHHC
PVPQYDPSWLDLEETIQETSRGEDPLLEQARQLVRQLGTASTSLLQRRLRIGYNRAARLM
CCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHCHHHHHHHH
EQLEAEGIVGPAEGARGRVVYLGDE
HHHHHCCCCCCCCCCCCEEEEECCC
>Mature Secondary Structure 
ARKRAKERRTRGETAPLAAGSQRRRLRAIVTRLAQVAALVPRRLPRDLAGLFLATVGVL
CCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
LTLALFGHERETGLAGWFAQTCRQLFGRGAIVVPLACWWGALELVASRSRAGTVRRAVGL
HHHHHHCCCCCCCHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALYGSAAVALLDARPADQVEEAGGYIGAGVAALLRLIGGDLGLGLLALALGLAGSTLVAG
HHHCCHHEEEECCCCHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHH
IELGTLARTILTAARRTGQIVRRRSSARAVDLPASPAPAESGRSDETVQRETTRPVIATR
HHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCHHHHHCCCCEEEEC
HTPASRSRGRRTPVSPQQRVQERPSGEPEPVAANAATPAAAGDQVLPEISRLQRYEASLP
CCCCHHHCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCC
DAEELERKAAIIQETLANFRVDARVREIYPGPAVTLFTLEPGPGVKVRRITELQNDLALA
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCEEHHHHHHHHHHHHH
LAAPAIRIEAPVPGMARVGIEVPNSAISTVGLREVLESATFQRSRARLPLALGRDVHGEY
HCCCCEEEECCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCCCCCE
VVADLTRMPHLLIAGATGSGKSVCINGIIATFLLTRRPDELQMLLIDPKKVELAGYDGVP
EEHHHHHCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCEEEEECCCCCC
HLKRPVVTDMGLVVGALRRVLQEMERRYELFAQLGVRNLEGYRLRREEDPSLEPLPYLVV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHH
IIDELADLMLTTPDEVETLLVRLAQMARATGIHLLIATQRPSVDVLTGLIKANVPARIAF
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCEEEEEEECCCCHHHHHHHHHCCCCCEEEE
AVTSQTDSRVILDMPGAERLLGRGDMLYLPPDAARPLRVQGSFIDDRDLEYVVEHWRQLY
EEECCCCCEEEEECCCHHHHHCCCCEEEECCCCCCCEEEECCCCCCCCHHHHHHHHHHHC
PVPQYDPSWLDLEETIQETSRGEDPLLEQARQLVRQLGTASTSLLQRRLRIGYNRAARLM
CCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHCHHHHHHHH
EQLEAEGIVGPAEGARGRVVYLGDE
HHHHHCCCCCCCCCCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3129532; 2507870; 9384377; 8160014; 10588743; 11062134; 11778051 [H]