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The map label for this gene is xylH [H]

Identifier: 22127924

GI number: 22127924

Start: 4496262

End: 4497455

Strand: Reverse

Name: xylH [H]

Synonym: y4054

Alternate gene names: 22127924

Gene position: 4497455-4496262 (Counterclockwise)

Preceding gene: 22127925

Following gene: 22127923

Centisome position: 97.75

GC content: 52.09

Gene sequence:

>1194_bases
GTGAAACCCATGTCACAAGCTAATCAATCTGAATTTAACTCACCAGAAAATGGGGATAAAAAGCCATTTTTTCGGCTTAA
ATCCTTAAATTTACAAGTTTTTGTCATGCTGGCCGCGATCGCCATTATTATGTTGTTCTTCACCTTCACGACAGAAGGGG
CCTATCTCAGCGCCAGAAATATCTCTAACTTGCTGCGCCAGACGGCGATCACCGGCATCTTGGCGGTCGGTATGGTGTTT
GTCATTATCTCCGCCGAAATTGACTTGTCTGTTGGCTCAATGATGGGGTTATTGGGTGGCATAGCGGCCATTTTTGATGT
CTGGCTCGGCTGGCCGTTGCCGCTGACCATTGTCGTTACGCTGGCGCTGGGGCTGGTATTAGGGGCATGGAACGGTTGGT
GGGTCGCGTATCGCAAAGTGCCTTCGTTTATTGTTACGCTCGCGGGCATGTTGGCTTTTCGTGGCATTTTAATTGGTATC
ACCAATGGCACGACGGTTTCGCCGACCAGTAATGCGATGTCGCAGATTGGCCAGAGCTATCTGCCAAGTGGCATTGGTTT
TGGCATCGGTGCTATTGGCCTGATGTTGTTTGTGGCCTGGCAATGGCGTCGGCGTAATCACCGCATCCGCTTGGGGTTAC
CGGTTGCCGCCCCGCAAGGGGATGTGACTCGCCAAACTATTACCGCAGTTATCGTTCTGGGTGCCATATATTTATTGAAT
GATTATCGTGGTGTACCTACGCCGGTACTAATCCTTACTGCATTAATGCTGGCGGGGGTATTTATGGCTACTCGCACCGC
TTTTGGTCGCCGGATCTACGCTATTGGCGGCAATATTGATGCGGCGCGCCTGTCTGGAATTAATGTAGAGCGCACTAAAC
TGGCAGTATTCGCGATTAACGGACTGATGGTGGCGATGGCTGGTTTGATCCTCAGTTCACGTTTAGGCGCAGGTTCGCCT
TCTGCGGGCAATATCGCTGAACTGGATGCGATTGCGGCGTGTGTCATTGGCGGTACCAGCCTGGCCGGAGGCGTTGGCAG
TGTGGCGGGGGCCGTAATGGGCGCATTTATTATGGCTTCTCTCGATAATGGGATGAGCATGCTAGATGTGCCGACGTTCT
GGCAGTACATTGTCAAAGGCGCAATTTTGCTGCTGGCCGTGTGGATGGATTCCGCCACCAAACGGCGGGTGTGA

Upstream 100 bases:

>100_bases
TTAAGTGATCGGGTGCTGGTCATGCATCAGGGGCGCATCAAAGCCGATCTTATCAACCATAACCTGACTCAAGAAAAGGT
CATGGAAGCCGCACTCAGGA

Downstream 100 bases:

>100_bases
CTTTATCCCATAGGAAAATCAGTGCCATACCGCGCTGATTTTTCTGCCTGTTCAGCCTTGATATCCCATGCATTTCAGGA
GCTACCCCCATGTTTGAAAA

Product: sugar transport system permease

Products: ADP; phosphate; xylose [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 397; Mature: 397

Protein sequence:

>397_residues
MKPMSQANQSEFNSPENGDKKPFFRLKSLNLQVFVMLAAIAIIMLFFTFTTEGAYLSARNISNLLRQTAITGILAVGMVF
VIISAEIDLSVGSMMGLLGGIAAIFDVWLGWPLPLTIVVTLALGLVLGAWNGWWVAYRKVPSFIVTLAGMLAFRGILIGI
TNGTTVSPTSNAMSQIGQSYLPSGIGFGIGAIGLMLFVAWQWRRRNHRIRLGLPVAAPQGDVTRQTITAVIVLGAIYLLN
DYRGVPTPVLILTALMLAGVFMATRTAFGRRIYAIGGNIDAARLSGINVERTKLAVFAINGLMVAMAGLILSSRLGAGSP
SAGNIAELDAIAACVIGGTSLAGGVGSVAGAVMGAFIMASLDNGMSMLDVPTFWQYIVKGAILLLAVWMDSATKRRV

Sequences:

>Translated_397_residues
MKPMSQANQSEFNSPENGDKKPFFRLKSLNLQVFVMLAAIAIIMLFFTFTTEGAYLSARNISNLLRQTAITGILAVGMVF
VIISAEIDLSVGSMMGLLGGIAAIFDVWLGWPLPLTIVVTLALGLVLGAWNGWWVAYRKVPSFIVTLAGMLAFRGILIGI
TNGTTVSPTSNAMSQIGQSYLPSGIGFGIGAIGLMLFVAWQWRRRNHRIRLGLPVAAPQGDVTRQTITAVIVLGAIYLLN
DYRGVPTPVLILTALMLAGVFMATRTAFGRRIYAIGGNIDAARLSGINVERTKLAVFAINGLMVAMAGLILSSRLGAGSP
SAGNIAELDAIAACVIGGTSLAGGVGSVAGAVMGAFIMASLDNGMSMLDVPTFWQYIVKGAILLLAVWMDSATKRRV
>Mature_397_residues
MKPMSQANQSEFNSPENGDKKPFFRLKSLNLQVFVMLAAIAIIMLFFTFTTEGAYLSARNISNLLRQTAITGILAVGMVF
VIISAEIDLSVGSMMGLLGGIAAIFDVWLGWPLPLTIVVTLALGLVLGAWNGWWVAYRKVPSFIVTLAGMLAFRGILIGI
TNGTTVSPTSNAMSQIGQSYLPSGIGFGIGAIGLMLFVAWQWRRRNHRIRLGLPVAAPQGDVTRQTITAVIVLGAIYLLN
DYRGVPTPVLILTALMLAGVFMATRTAFGRRIYAIGGNIDAARLSGINVERTKLAVFAINGLMVAMAGLILSSRLGAGSP
SAGNIAELDAIAACVIGGTSLAGGVGSVAGAVMGAFIMASLDNGMSMLDVPTFWQYIVKGAILLLAVWMDSATKRRV

Specific function: Part of the binding-protein-dependent transport system for D-xylose. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG4214

COG function: function code G; ABC-type xylose transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. AraH/rbsC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789992, Length=395, Percent_Identity=84.5569620253165, Blast_Score=595, Evalue=1e-171,
Organism=Escherichia coli, GI1790191, Length=341, Percent_Identity=36.3636363636364, Blast_Score=160, Evalue=1e-40,
Organism=Escherichia coli, GI1788896, Length=156, Percent_Identity=41.025641025641, Blast_Score=131, Evalue=8e-32,
Organism=Escherichia coli, GI145693152, Length=341, Percent_Identity=31.6715542521994, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1790524, Length=152, Percent_Identity=40.1315789473684, Blast_Score=112, Evalue=4e-26,
Organism=Escherichia coli, GI1788471, Length=133, Percent_Identity=44.3609022556391, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1787793, Length=163, Percent_Identity=36.8098159509202, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI87082395, Length=345, Percent_Identity=29.5652173913043, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1787794, Length=156, Percent_Identity=31.4102564102564, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI145693214, Length=310, Percent_Identity=31.6129032258064, Blast_Score=72, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001851 [H]

Pfam domain/function: PF02653 BPD_transp_2 [H]

EC number: NA

Molecular weight: Translated: 42019; Mature: 42019

Theoretical pI: Translated: 10.77; Mature: 10.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCC
>Mature Secondary Structure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HCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; xylose [Periplasm]; H2O [C]

Specific reaction: ATP + xylose [Periplasm] + H2O = ADP + phosphate + xylose [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]