Click here to switch to the map view.

The map label for this gene is rpe [H]

Identifier: 22127808

GI number: 22127808

Start: 4392657

End: 4393346

Strand: Direct

Name: rpe [H]

Synonym: y3938

Alternate gene names: 22127808

Gene position: 4392657-4393346 (Clockwise)

Preceding gene: 22127807

Following gene: 161484727

Centisome position: 95.48

GC content: 49.71

Gene sequence:

>690_bases
TTGGAGAAACGGATGAAAAAGTATTTAATTGCCCCCTCTATTCTGTCAGCTGATTTTGCCCGGCTGGGTGAAGATACCGC
GAAGGTACTCGCCGCAGGTGCTGATATTGTGCATTTTGACGTGATGGACAACCACTATGTTCCTAACCTGACCATCGGGC
CGATGGTGTGCAAGGCTCTGCGTGATTACGGGATCACCGCACCTATTGATGTGCATCTGATGGTTAAACCGGTTGACCGT
ATCGTCCCGGATTTCGCCAAAGCCGGTGCAACCTATATTACATTCCATCCCGAAGCTTCTGAACACGTTGACCGCACGCT
GCAATTGATCAAAGAGAGTGGTTGTAAGGCCGGTCTGGTGTTCAACCCAGCGACTCCCCTGAGCTATCTTGACTATGTGA
TGGATAAGCTGGATGTCATTTTGCTGATGTCAGTTAACCCCGGTTTCGGTGGTCAATCGTTTATTCCTGAAACCCTGAAT
AAGCTGCGTCAGGTGCGTAAGTTGATTGATGACAGCGGTTATGACATCCGTTTGGAAGTGGACGGCGGTGTTAAGGTTGA
GAATATTCGCCAAATAGCCGCAGCAGGTGCCGATATGTTTGTTGCTGGCTCCGCGATTTTCAATCAACCCGATTATGCTG
CGGTGATCGATGCCATGCGCAATGAACTGGCGATGGCGGCTAATGGTTAA

Upstream 100 bases:

>100_bases
GGCTTACTCAATTGCCGCCTTCCTGCAACTCGAATTATTTGGGGTATAGCCCGGTGTCCAGGTTGATAAAGCCGATCTTT
CATAAGACGAAGCAACATGT

Downstream 100 bases:

>100_bases
GTTTAAGGCGATTCGTGGTGTTGCATTCGATCTGGATGGCACATTAGTCGACAGCGCGCCCGGTCTGGCCCGTGCAATTG
ATATGGCGTTGGCGCATCAG

Product: ribulose-phosphate 3-epimerase

Products: NA

Alternate protein names: Pentose-5-phosphate 3-epimerase; PPE; R5P3E [H]

Number of amino acids: Translated: 229; Mature: 229

Protein sequence:

>229_residues
MEKRMKKYLIAPSILSADFARLGEDTAKVLAAGADIVHFDVMDNHYVPNLTIGPMVCKALRDYGITAPIDVHLMVKPVDR
IVPDFAKAGATYITFHPEASEHVDRTLQLIKESGCKAGLVFNPATPLSYLDYVMDKLDVILLMSVNPGFGGQSFIPETLN
KLRQVRKLIDDSGYDIRLEVDGGVKVENIRQIAAAGADMFVAGSAIFNQPDYAAVIDAMRNELAMAANG

Sequences:

>Translated_229_residues
MEKRMKKYLIAPSILSADFARLGEDTAKVLAAGADIVHFDVMDNHYVPNLTIGPMVCKALRDYGITAPIDVHLMVKPVDR
IVPDFAKAGATYITFHPEASEHVDRTLQLIKESGCKAGLVFNPATPLSYLDYVMDKLDVILLMSVNPGFGGQSFIPETLN
KLRQVRKLIDDSGYDIRLEVDGGVKVENIRQIAAAGADMFVAGSAIFNQPDYAAVIDAMRNELAMAANG
>Mature_229_residues
MEKRMKKYLIAPSILSADFARLGEDTAKVLAAGADIVHFDVMDNHYVPNLTIGPMVCKALRDYGITAPIDVHLMVKPVDR
IVPDFAKAGATYITFHPEASEHVDRTLQLIKESGCKAGLVFNPATPLSYLDYVMDKLDVILLMSVNPGFGGQSFIPETLN
KLRQVRKLIDDSGYDIRLEVDGGVKVENIRQIAAAGADMFVAGSAIFNQPDYAAVIDAMRNELAMAANG

Specific function: Unknown

COG id: COG0036

COG function: function code G; Pentose-5-phosphate-3-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribulose-phosphate 3-epimerase family [H]

Homologues:

Organism=Homo sapiens, GI40385883, Length=220, Percent_Identity=40.4545454545455, Blast_Score=163, Evalue=1e-40,
Organism=Homo sapiens, GI219879828, Length=220, Percent_Identity=39.0909090909091, Blast_Score=153, Evalue=1e-37,
Organism=Homo sapiens, GI24307923, Length=176, Percent_Identity=34.0909090909091, Blast_Score=100, Evalue=1e-21,
Organism=Escherichia coli, GI1789788, Length=224, Percent_Identity=87.0535714285714, Blast_Score=404, Evalue=1e-114,
Organism=Escherichia coli, GI1790523, Length=204, Percent_Identity=37.2549019607843, Blast_Score=149, Evalue=1e-37,
Organism=Escherichia coli, GI1790754, Length=208, Percent_Identity=30.2884615384615, Blast_Score=96, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17552948, Length=223, Percent_Identity=41.7040358744395, Blast_Score=160, Evalue=4e-40,
Organism=Saccharomyces cerevisiae, GI6322341, Length=232, Percent_Identity=39.6551724137931, Blast_Score=161, Evalue=6e-41,
Organism=Drosophila melanogaster, GI24586301, Length=212, Percent_Identity=39.622641509434, Blast_Score=156, Evalue=8e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR000056
- InterPro:   IPR011060 [H]

Pfam domain/function: PF00834 Ribul_P_3_epim [H]

EC number: =5.1.3.1 [H]

Molecular weight: Translated: 24971; Mature: 24971

Theoretical pI: Translated: 5.31; Mature: 5.31

Prosite motif: PS01085 RIBUL_P_3_EPIMER_1 ; PS01086 RIBUL_P_3_EPIMER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKRMKKYLIAPSILSADFARLGEDTAKVLAAGADIVHFDVMDNHYVPNLTIGPMVCKAL
CCHHHHHHHHCHHHHHHHHHHHCHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHH
RDYGITAPIDVHLMVKPVDRIVPDFAKAGATYITFHPEASEHVDRTLQLIKESGCKAGLV
HHCCCCCCEEEEEEECCHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHCCCCCCEE
FNPATPLSYLDYVMDKLDVILLMSVNPGFGGQSFIPETLNKLRQVRKLIDDSGYDIRLEV
ECCCCHHHHHHHHHHHHCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEE
DGGVKVENIRQIAAAGADMFVAGSAIFNQPDYAAVIDAMRNELAMAANG
CCCCCHHHHHHHHHCCCCCEEECHHHHCCCCHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MEKRMKKYLIAPSILSADFARLGEDTAKVLAAGADIVHFDVMDNHYVPNLTIGPMVCKAL
CCHHHHHHHHCHHHHHHHHHHHCHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHH
RDYGITAPIDVHLMVKPVDRIVPDFAKAGATYITFHPEASEHVDRTLQLIKESGCKAGLV
HHCCCCCCEEEEEEECCHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHCCCCCCEE
FNPATPLSYLDYVMDKLDVILLMSVNPGFGGQSFIPETLNKLRQVRKLIDDSGYDIRLEV
ECCCCHHHHHHHHHHHHCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEE
DGGVKVENIRQIAAAGADMFVAGSAIFNQPDYAAVIDAMRNELAMAANG
CCCCCHHHHHHHHHCCCCCEEECHHHHCCCCHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]