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The map label for this gene is glgP [H]

Identifier: 22127761

GI number: 22127761

Start: 4343688

End: 4346207

Strand: Direct

Name: glgP [H]

Synonym: y3890

Alternate gene names: 22127761

Gene position: 4343688-4346207 (Clockwise)

Preceding gene: 22127760

Following gene: 22127763

Centisome position: 94.41

GC content: 47.06

Gene sequence:

>2520_bases
TTGTTAGCGCTCGTTATTGTTGGCGCTCGTCATTGTCGACTCGTTGTAGCCATTAAACTTGGGAAAAACGTTATGACATC
ACCGTTTAGCTATACCTCACCCGTTGTCAGTGTGGATGCACTGAAACACTCTATTGCCTATAAGCTAATGTTTATTATTG
GCAAAGATCCCACCATTGCGACGCAACATGATTGGTTGAATGCAACTCTATTTGCGGTACGTGATCGCATGGTTGAACGT
TGGTTACGTTCTAATCGCGCTCAATTATCACAGGACGTTCGGCAGGTTTATTATCTATCGATGGAGTTTTTACTGGGCAG
AACATTATCTAACGCGCTGTTATCAATGGGGATTTATGATGAGATCGAGCAGGCGTTGGATGAAATGGGCCTCAGTTTGT
CAGAGTTGTTGAAAGAGGAGAACGATCCCGGTTTAGGTAATGGTGGTTTAGGCCGTCTGGCAGCGTGTTTCCTCGATTCA
TTGGCCACCCTCGCGCTACCAGGGCGGGGTTACGGCATTCGTTATGAATATGGCATGTTCAGCCAGAAAATTGTTAACGG
CCAACAGATGGAGTCGCCAGATAACTGGTTGGAATATGGCAATGCATGGGAGTTTCCACGGCACAACACCCGCTATAAAG
TCCGGTTCGGTGGCCGTATTCAGCAAGAAGGCAGCAAGATTCGCTGGTTAGAAACCGAAGAAATCCTCGCGTGTGCCTAT
GATCAAATTATTCCTGGTTTTGATACTGATGCCACCAATACATTGCGCTTATGGTCTGCGCAGGCCAGTAATGAAATTAA
TCTGGGCAAATTTAATCAAGGCGATTACTTTGCCGCAGTTGAAGATAAAAACCATTCAGAGAACGTCTCTCGAGTCCTAT
ACCCCGATGATTCCACCTATTCCGGGCGTGAATTACGCTTGCGACAAGAGTACTTTTTAGTCTCAGCGACAGTGCAGGAT
ATTCTGAACCGCCATTGGGCGATGCATCATACATTCAATAACTTAGCCGATAAAATTGCTATTCATCTGAATGATACACA
CCCGGTGCTTTCCATTCCTGAAATGATGCGTCTACTGATCGACGAGCATAAATTTACCTGGATGGACGCATGGGATGTGG
TGCAACAAGTGTTTTCCTACACCAACCATACGTTGATGAGTGAGGCGCTGGAGACCTGGCCTGTCGATATGATCGGTAAG
ATTTTGCCACGCCATCTGCAAATCATCTTTGATATCAATGATCATTTCCTCAAGCTGGTGGAGGAACAATATCCTGACGA
TAAAGAGCTGCTCTCAAGGGTATCGGTTATTGACGAAAATAACGGCCGACGGATACGAATGGCCTGGCTGGCGGTGATTG
CCAGCCACAAAGTGAACGGCGTTTCTGCGTTACATTCTGAACTGATGGTGCAATCGTTGTTTGCTGATTTTGCTCGTATT
TTCCCTAACCGTTTCTGCAATAAAACCAACGGCGTGACACCACGGCGCTGGTTGGGGTTAGCCAACCGGCCCTTGGCGGC
AGTGCTGGATGACAGTATTGGCCAGACCTGGCGTACTGACCTGAGCCAACTTAGCGAACTGGAAAAGAACCTTGATTACC
CCAGTTTCTTACTGGCCTTACAAAAGGCCAAGCTGGAAAACAAAAAACGGCTGGCGGTTTACATCGCTGAAAAACTCAAT
ATCGTGGTCAATCCGGCAGCGTTGTTTGACGTACAAATCAAACGTATTCACGAGTACAAGCGGCAATTGCTGAATGTGCT
ACATGTGATAACGCGTTATAACCGCATTATTGACGCGCCTGACAATAACTGGGTGCCTCGGGTGGTGATTTTTGCCGGTA
AAGCCGCCTCGGCTTATTATAATGCCAAGCAAATTATTCACCTGATCAACGACGTAGCGAAGGTTATCAACAACGATCCA
CGGATCAATAATTTATTGAAAGTGGTCTTTATTCCTAACTACAGTGTGAGCTTGGCGCAGTTGATCATTCCGGCGGCCGA
CTTGTCCGAACAGATCTCGTTGGCGGGTACAGAAGCGTCGGGGACCAGTAATATGAAGTTTGCGCTAAACGGAGCGCTAA
CCATTGGTACATTAGACGGTGCCAATGTGGAGATCCGCGAGCATGTCGGTGAAGAGAATATCTTTATCTTCGGGAATACG
ACTGAGCAGGTTGAAGCATTGCGTAAGAGTGGCTATAACCCACGGAAATATTACGACGAGGATCCTGAGTTACATCAGGT
ACTGACACAGATAGCGACAGGCACGTTCAGCCCAGAAGAGCCTCATCGCTATACCAACCTGTTTGATTCGCTGGTCAATT
TGGGGGATCACTACCAGCTATTGGCGGATTATCGCAGCTATGTGGACACTCAAGAGCAAGTCGATGCGCTGTATCGCAAC
CGGGATGAATGGTCGCGTAAAACCTTACTGAATATTGCCAATATGGGTTATTTCTCTTCAGACCGGACGATTAAGGAGTA
TGCCGATGAGATTTGGCATATTAAGCCTATCCGGCTGTAG

Upstream 100 bases:

>100_bases
GCCGTAGATTATTTGTCACTTTATCGACGTCTGTAATTGTTGAAACTGATAATTGTTGGAGCTGGTAATTGTTGGAGCTG
GTAATCGTTGAAACTGGTAA

Downstream 100 bases:

>100_bases
TGTGCGGTAATGACATATTCAACCGCCAGTGCCACCGTAAAAAACCCTCTTCGCGGTTATCCGATTGAAGAGGGTTTTTA
AATTTCTTGAGGTGCTTGAA

Product: glycogen phosphorylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 839; Mature: 839

Protein sequence:

>839_residues
MLALVIVGARHCRLVVAIKLGKNVMTSPFSYTSPVVSVDALKHSIAYKLMFIIGKDPTIATQHDWLNATLFAVRDRMVER
WLRSNRAQLSQDVRQVYYLSMEFLLGRTLSNALLSMGIYDEIEQALDEMGLSLSELLKEENDPGLGNGGLGRLAACFLDS
LATLALPGRGYGIRYEYGMFSQKIVNGQQMESPDNWLEYGNAWEFPRHNTRYKVRFGGRIQQEGSKIRWLETEEILACAY
DQIIPGFDTDATNTLRLWSAQASNEINLGKFNQGDYFAAVEDKNHSENVSRVLYPDDSTYSGRELRLRQEYFLVSATVQD
ILNRHWAMHHTFNNLADKIAIHLNDTHPVLSIPEMMRLLIDEHKFTWMDAWDVVQQVFSYTNHTLMSEALETWPVDMIGK
ILPRHLQIIFDINDHFLKLVEEQYPDDKELLSRVSVIDENNGRRIRMAWLAVIASHKVNGVSALHSELMVQSLFADFARI
FPNRFCNKTNGVTPRRWLGLANRPLAAVLDDSIGQTWRTDLSQLSELEKNLDYPSFLLALQKAKLENKKRLAVYIAEKLN
IVVNPAALFDVQIKRIHEYKRQLLNVLHVITRYNRIIDAPDNNWVPRVVIFAGKAASAYYNAKQIIHLINDVAKVINNDP
RINNLLKVVFIPNYSVSLAQLIIPAADLSEQISLAGTEASGTSNMKFALNGALTIGTLDGANVEIREHVGEENIFIFGNT
TEQVEALRKSGYNPRKYYDEDPELHQVLTQIATGTFSPEEPHRYTNLFDSLVNLGDHYQLLADYRSYVDTQEQVDALYRN
RDEWSRKTLLNIANMGYFSSDRTIKEYADEIWHIKPIRL

Sequences:

>Translated_839_residues
MLALVIVGARHCRLVVAIKLGKNVMTSPFSYTSPVVSVDALKHSIAYKLMFIIGKDPTIATQHDWLNATLFAVRDRMVER
WLRSNRAQLSQDVRQVYYLSMEFLLGRTLSNALLSMGIYDEIEQALDEMGLSLSELLKEENDPGLGNGGLGRLAACFLDS
LATLALPGRGYGIRYEYGMFSQKIVNGQQMESPDNWLEYGNAWEFPRHNTRYKVRFGGRIQQEGSKIRWLETEEILACAY
DQIIPGFDTDATNTLRLWSAQASNEINLGKFNQGDYFAAVEDKNHSENVSRVLYPDDSTYSGRELRLRQEYFLVSATVQD
ILNRHWAMHHTFNNLADKIAIHLNDTHPVLSIPEMMRLLIDEHKFTWMDAWDVVQQVFSYTNHTLMSEALETWPVDMIGK
ILPRHLQIIFDINDHFLKLVEEQYPDDKELLSRVSVIDENNGRRIRMAWLAVIASHKVNGVSALHSELMVQSLFADFARI
FPNRFCNKTNGVTPRRWLGLANRPLAAVLDDSIGQTWRTDLSQLSELEKNLDYPSFLLALQKAKLENKKRLAVYIAEKLN
IVVNPAALFDVQIKRIHEYKRQLLNVLHVITRYNRIIDAPDNNWVPRVVIFAGKAASAYYNAKQIIHLINDVAKVINNDP
RINNLLKVVFIPNYSVSLAQLIIPAADLSEQISLAGTEASGTSNMKFALNGALTIGTLDGANVEIREHVGEENIFIFGNT
TEQVEALRKSGYNPRKYYDEDPELHQVLTQIATGTFSPEEPHRYTNLFDSLVNLGDHYQLLADYRSYVDTQEQVDALYRN
RDEWSRKTLLNIANMGYFSSDRTIKEYADEIWHIKPIRL
>Mature_839_residues
MLALVIVGARHCRLVVAIKLGKNVMTSPFSYTSPVVSVDALKHSIAYKLMFIIGKDPTIATQHDWLNATLFAVRDRMVER
WLRSNRAQLSQDVRQVYYLSMEFLLGRTLSNALLSMGIYDEIEQALDEMGLSLSELLKEENDPGLGNGGLGRLAACFLDS
LATLALPGRGYGIRYEYGMFSQKIVNGQQMESPDNWLEYGNAWEFPRHNTRYKVRFGGRIQQEGSKIRWLETEEILACAY
DQIIPGFDTDATNTLRLWSAQASNEINLGKFNQGDYFAAVEDKNHSENVSRVLYPDDSTYSGRELRLRQEYFLVSATVQD
ILNRHWAMHHTFNNLADKIAIHLNDTHPVLSIPEMMRLLIDEHKFTWMDAWDVVQQVFSYTNHTLMSEALETWPVDMIGK
ILPRHLQIIFDINDHFLKLVEEQYPDDKELLSRVSVIDENNGRRIRMAWLAVIASHKVNGVSALHSELMVQSLFADFARI
FPNRFCNKTNGVTPRRWLGLANRPLAAVLDDSIGQTWRTDLSQLSELEKNLDYPSFLLALQKAKLENKKRLAVYIAEKLN
IVVNPAALFDVQIKRIHEYKRQLLNVLHVITRYNRIIDAPDNNWVPRVVIFAGKAASAYYNAKQIIHLINDVAKVINNDP
RINNLLKVVFIPNYSVSLAQLIIPAADLSEQISLAGTEASGTSNMKFALNGALTIGTLDGANVEIREHVGEENIFIFGNT
TEQVEALRKSGYNPRKYYDEDPELHQVLTQIATGTFSPEEPHRYTNLFDSLVNLGDHYQLLADYRSYVDTQEQVDALYRN
RDEWSRKTLLNIANMGYFSSDRTIKEYADEIWHIKPIRL

Specific function: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties [

COG id: COG0058

COG function: function code G; Glucan phosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycogen phosphorylase family [H]

Homologues:

Organism=Homo sapiens, GI21361370, Length=807, Percent_Identity=50.8054522924411, Blast_Score=811, Evalue=0.0,
Organism=Homo sapiens, GI5032009, Length=815, Percent_Identity=49.5705521472393, Blast_Score=803, Evalue=0.0,
Organism=Homo sapiens, GI71037379, Length=813, Percent_Identity=50.0615006150061, Blast_Score=799, Evalue=0.0,
Organism=Homo sapiens, GI255653002, Length=813, Percent_Identity=48.7084870848708, Blast_Score=752, Evalue=0.0,
Organism=Homo sapiens, GI257900462, Length=668, Percent_Identity=50.1497005988024, Blast_Score=693, Evalue=0.0,
Organism=Escherichia coli, GI2367228, Length=815, Percent_Identity=79.3865030674847, Blast_Score=1352, Evalue=0.0,
Organism=Escherichia coli, GI48994936, Length=768, Percent_Identity=47.0052083333333, Blast_Score=725, Evalue=0.0,
Organism=Caenorhabditis elegans, GI32566204, Length=813, Percent_Identity=49.8154981549816, Blast_Score=821, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17564550, Length=811, Percent_Identity=49.9383477188656, Blast_Score=820, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6325418, Length=812, Percent_Identity=47.1674876847291, Blast_Score=721, Evalue=0.0,
Organism=Drosophila melanogaster, GI78706832, Length=810, Percent_Identity=50.4938271604938, Blast_Score=823, Evalue=0.0,
Organism=Drosophila melanogaster, GI24581010, Length=810, Percent_Identity=50.4938271604938, Blast_Score=823, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011833
- InterPro:   IPR000811 [H]

Pfam domain/function: PF00343 Phosphorylase [H]

EC number: =2.4.1.1 [H]

Molecular weight: Translated: 95937; Mature: 95937

Theoretical pI: Translated: 6.38; Mature: 6.38

Prosite motif: PS00102 PHOSPHORYLASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLALVIVGARHCRLVVAIKLGKNVMTSPFSYTSPVVSVDALKHSIAYKLMFIIGKDPTIA
CEEEEEECCCCEEEEEEEEECCCHHCCCCCCCCCCHHHHHHHHHHHHEEEEEEECCCCCE
TQHDWLNATLFAVRDRMVERWLRSNRAQLSQDVRQVYYLSMEFLLGRTLSNALLSMGIYD
ECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
EIEQALDEMGLSLSELLKEENDPGLGNGGLGRLAACFLDSLATLALPGRGYGIRYEYGMF
HHHHHHHHHCCCHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEECCCH
SQKIVNGQQMESPDNWLEYGNAWEFPRHNTRYKVRFGGRIQQEGSKIRWLETEEILACAY
HHHHCCCCCCCCCHHHHHCCCCCCCCCCCCEEEEEECCEECCCCCEEEEECHHHHHHHHH
DQIIPGFDTDATNTLRLWSAQASNEINLGKFNQGDYFAAVEDKNHSENVSRVLYPDDSTY
HHHCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCEEEEECCCCCCCCCCEEECCCCCCC
SGRELRLRQEYFLVSATVQDILNRHWAMHHTFNNLADKIAIHLNDTHPVLSIPEMMRLLI
CCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCHHHHHHHHH
DEHKFTWMDAWDVVQQVFSYTNHTLMSEALETWPVDMIGKILPRHLQIIFDINDHFLKLV
HCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHEEEEEECCHHHHHHH
EEQYPDDKELLSRVSVIDENNGRRIRMAWLAVIASHKVNGVSALHSELMVQSLFADFARI
HHHCCCHHHHHHHHHHHCCCCCCEEHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
FPNRFCNKTNGVTPRRWLGLANRPLAAVLDDSIGQTWRTDLSQLSELEKNLDYPSFLLAL
HHHHHCCCCCCCCHHHHHCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHH
QKAKLENKKRLAVYIAEKLNIVVNPAALFDVQIKRIHEYKRQLLNVLHVITRYNRIIDAP
HHHHHCCCCEEEEEEEECCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECC
DNNWVPRVVIFAGKAASAYYNAKQIIHLINDVAKVINNDPRINNLLKVVFIPNYSVSLAQ
CCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCHHHHH
LIIPAADLSEQISLAGTEASGTSNMKFALNGALTIGTLDGANVEIREHVGEENIFIFGNT
HHHCHHCHHHHHEECCCCCCCCCCEEEEEECEEEEEECCCCCCHHHHHCCCCCEEEECCC
TEQVEALRKSGYNPRKYYDEDPELHQVLTQIATGTFSPEEPHRYTNLFDSLVNLGDHYQL
HHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCHHHHH
LADYRSYVDTQEQVDALYRNRDEWSRKTLLNIANMGYFSSDRTIKEYADEIWHIKPIRL
HHHHHHHCCCHHHHHHHHHCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MLALVIVGARHCRLVVAIKLGKNVMTSPFSYTSPVVSVDALKHSIAYKLMFIIGKDPTIA
CEEEEEECCCCEEEEEEEEECCCHHCCCCCCCCCCHHHHHHHHHHHHEEEEEEECCCCCE
TQHDWLNATLFAVRDRMVERWLRSNRAQLSQDVRQVYYLSMEFLLGRTLSNALLSMGIYD
ECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
EIEQALDEMGLSLSELLKEENDPGLGNGGLGRLAACFLDSLATLALPGRGYGIRYEYGMF
HHHHHHHHHCCCHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEECCCH
SQKIVNGQQMESPDNWLEYGNAWEFPRHNTRYKVRFGGRIQQEGSKIRWLETEEILACAY
HHHHCCCCCCCCCHHHHHCCCCCCCCCCCCEEEEEECCEECCCCCEEEEECHHHHHHHHH
DQIIPGFDTDATNTLRLWSAQASNEINLGKFNQGDYFAAVEDKNHSENVSRVLYPDDSTY
HHHCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCEEEEECCCCCCCCCCEEECCCCCCC
SGRELRLRQEYFLVSATVQDILNRHWAMHHTFNNLADKIAIHLNDTHPVLSIPEMMRLLI
CCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCHHHHHHHHH
DEHKFTWMDAWDVVQQVFSYTNHTLMSEALETWPVDMIGKILPRHLQIIFDINDHFLKLV
HCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHEEEEEECCHHHHHHH
EEQYPDDKELLSRVSVIDENNGRRIRMAWLAVIASHKVNGVSALHSELMVQSLFADFARI
HHHCCCHHHHHHHHHHHCCCCCCEEHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
FPNRFCNKTNGVTPRRWLGLANRPLAAVLDDSIGQTWRTDLSQLSELEKNLDYPSFLLAL
HHHHHCCCCCCCCHHHHHCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHH
QKAKLENKKRLAVYIAEKLNIVVNPAALFDVQIKRIHEYKRQLLNVLHVITRYNRIIDAP
HHHHHCCCCEEEEEEEECCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECC
DNNWVPRVVIFAGKAASAYYNAKQIIHLINDVAKVINNDPRINNLLKVVFIPNYSVSLAQ
CCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCHHHHH
LIIPAADLSEQISLAGTEASGTSNMKFALNGALTIGTLDGANVEIREHVGEENIFIFGNT
HHHCHHCHHHHHEECCCCCCCCCCEEEEEECEEEEEECCCCCCHHHHHCCCCCEEEECCC
TEQVEALRKSGYNPRKYYDEDPELHQVLTQIATGTFSPEEPHRYTNLFDSLVNLGDHYQL
HHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCHHHHH
LADYRSYVDTQEQVDALYRNRDEWSRKTLLNIANMGYFSSDRTIKEYADEIWHIKPIRL
HHHHHHHCCCHHHHHHHHHCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2645169; 3047129; 9278503; 2975249; 3097003 [H]