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The map label for this gene is icc [H]

Identifier: 22127387

GI number: 22127387

Start: 3896179

End: 3897036

Strand: Reverse

Name: icc [H]

Synonym: y3513

Alternate gene names: 22127387

Gene position: 3897036-3896179 (Counterclockwise)

Preceding gene: 22127388

Following gene: 22127386

Centisome position: 84.7

GC content: 50.35

Gene sequence:

>858_bases
TTGGGGGGGCGGCAAAAACAAGGATACCATTTGGAAAGCCTGTTTAAACTGCCTATGGCGAGTGGGGCCAGGGTTAGAAT
TTTACAAATAACAGATACCCACCTCTTTGCTGGCGAACATGAGACATTGCTGGGTGTGAATACTTTTCACAGCTATCGCG
CGGTATTGGACGCGATTATTGCGGAACAGCACCCGTTTGATCTGGTTGTTGCCACGGGCGATTTGGCTCAGGACCACTCT
GTCGCCGCCTATCAGAATTTTGCGAAGGGAATATCTCGCCTGCCTGTGCCTTGCGTTTGGCTGCCCGGTAATCACGATTT
CCAGCCAGCAATGTTTGATGCATTGGCTGAGGCGGGGATTGCCCCTTCAAAACAGGTTCTGGCGGGAGAACACTGGCAGA
TCCTGTTGCTGGACAGCCAAGTATTTGGCGTACCTTATGGTGAGTTGAGCGACTATCAGTTGGAGTGGATGGAGCGCTGT
CTAATCGCGTATCCGGAACGTTACACCTTGATATTGTTGCACCATCATCCTATGCCGTCAGGTTGCACCTGGCTTGATCA
ACACAGTTTGCGCAACGCGCATATGTTGGCGGCGATCCTGACTCGTTATCCCCGAGTTACTACGTTATTGTGCGGTCATA
TTCATCAAGATTTAGATCTTGACTGGTATGGTAAGCGCTTGCTAGCCAGCCCTTCGACCTGTGTGCAATTTAAACCACAT
TGTACTAACTTTACGCTTGATGCTGTGGCACCAGGGTGGCGTTATCTCGATTTACTGCCTGACGGGGGGCTGGAAACTGA
GGTTCATCGGTTAGACAGTGACGAATTTTGCCCTGATATGGACTCGGATGGTTATTGA

Upstream 100 bases:

>100_bases
GTTGCGCTATTGTTTGGCGCATGGAGCGGTGGCCGTTCCGGTTTGTTAGACAGACTTATGGCCTTGCCTGCAGATAGTCA
TAATACGCATAACTATCTGG

Downstream 100 bases:

>100_bases
TGAGTACACTTTTATATATTCATGGTTTTAATAGCTCTCCCAGCTCAGCGAAAGCCACGGCGTTTAAAGAGTGGTTGCAG
CAACACTATCCGCATATAGA

Product: cyclic 3',5'-adenosine monophosphate phosphodiesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 285; Mature: 284

Protein sequence:

>285_residues
MGGRQKQGYHLESLFKLPMASGARVRILQITDTHLFAGEHETLLGVNTFHSYRAVLDAIIAEQHPFDLVVATGDLAQDHS
VAAYQNFAKGISRLPVPCVWLPGNHDFQPAMFDALAEAGIAPSKQVLAGEHWQILLLDSQVFGVPYGELSDYQLEWMERC
LIAYPERYTLILLHHHPMPSGCTWLDQHSLRNAHMLAAILTRYPRVTTLLCGHIHQDLDLDWYGKRLLASPSTCVQFKPH
CTNFTLDAVAPGWRYLDLLPDGGLETEVHRLDSDEFCPDMDSDGY

Sequences:

>Translated_285_residues
MGGRQKQGYHLESLFKLPMASGARVRILQITDTHLFAGEHETLLGVNTFHSYRAVLDAIIAEQHPFDLVVATGDLAQDHS
VAAYQNFAKGISRLPVPCVWLPGNHDFQPAMFDALAEAGIAPSKQVLAGEHWQILLLDSQVFGVPYGELSDYQLEWMERC
LIAYPERYTLILLHHHPMPSGCTWLDQHSLRNAHMLAAILTRYPRVTTLLCGHIHQDLDLDWYGKRLLASPSTCVQFKPH
CTNFTLDAVAPGWRYLDLLPDGGLETEVHRLDSDEFCPDMDSDGY
>Mature_284_residues
GGRQKQGYHLESLFKLPMASGARVRILQITDTHLFAGEHETLLGVNTFHSYRAVLDAIIAEQHPFDLVVATGDLAQDHSV
AAYQNFAKGISRLPVPCVWLPGNHDFQPAMFDALAEAGIAPSKQVLAGEHWQILLLDSQVFGVPYGELSDYQLEWMERCL
IAYPERYTLILLHHHPMPSGCTWLDQHSLRNAHMLAAILTRYPRVTTLLCGHIHQDLDLDWYGKRLLASPSTCVQFKPHC
TNFTLDAVAPGWRYLDLLPDGGLETEVHRLDSDEFCPDMDSDGY

Specific function: Affects the expression of the lacZ gene [H]

COG id: COG1409

COG function: function code R; Predicted phosphohydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1789410, Length=275, Percent_Identity=70.1818181818182, Blast_Score=387, Evalue=1e-109,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013622
- InterPro:   IPR004843
- ProDom:   PD587589 [H]

Pfam domain/function: PF00149 Metallophos; PF08413 Metallophos_C [H]

EC number: NA

Molecular weight: Translated: 32058; Mature: 31927

Theoretical pI: Translated: 5.75; Mature: 5.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGGRQKQGYHLESLFKLPMASGARVRILQITDTHLFAGEHETLLGVNTFHSYRAVLDAII
CCCCCCCCCCHHHHHHCCCCCCCEEEEEEEECCEEECCCCCEEEEEHHHHHHHHHHHHHH
AEQHPFDLVVATGDLAQDHSVAAYQNFAKGISRLPVPCVWLPGNHDFQPAMFDALAEAGI
HCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHCCC
APSKQVLAGEHWQILLLDSQVFGVPYGELSDYQLEWMERCLIAYPERYTLILLHHHPMPS
CCCHHHHCCCCEEEEEECCEEECCCCCCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCCC
GCTWLDQHSLRNAHMLAAILTRYPRVTTLLCGHIHQDLDLDWYGKRLLASPSTCVQFKPH
CCCCHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCHHCHHHHCCCCCEEEECCC
CTNFTLDAVAPGWRYLDLLPDGGLETEVHRLDSDEFCPDMDSDGY
CCCEEEECCCCCCEEEEECCCCCCCHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
GGRQKQGYHLESLFKLPMASGARVRILQITDTHLFAGEHETLLGVNTFHSYRAVLDAII
CCCCCCCCCHHHHHHCCCCCCCEEEEEEEECCEEECCCCCEEEEEHHHHHHHHHHHHHH
AEQHPFDLVVATGDLAQDHSVAAYQNFAKGISRLPVPCVWLPGNHDFQPAMFDALAEAGI
HCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHCCC
APSKQVLAGEHWQILLLDSQVFGVPYGELSDYQLEWMERCLIAYPERYTLILLHHHPMPS
CCCHHHHCCCCEEEEEECCEEECCCCCCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCCC
GCTWLDQHSLRNAHMLAAILTRYPRVTTLLCGHIHQDLDLDWYGKRLLASPSTCVQFKPH
CCCCHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCHHCHHHHCCCCCEEEECCC
CTNFTLDAVAPGWRYLDLLPDGGLETEVHRLDSDEFCPDMDSDGY
CCCEEEECCCCCCEEEEECCCCCCCHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]