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The map label for this gene is exbB [H]

Identifier: 22127369

GI number: 22127369

Start: 3876796

End: 3877857

Strand: Reverse

Name: exbB [H]

Synonym: y3495

Alternate gene names: 22127369

Gene position: 3877857-3876796 (Counterclockwise)

Preceding gene: 22127372

Following gene: 22127368

Centisome position: 84.29

GC content: 52.07

Gene sequence:

>1062_bases
ATGCATATTGGGTGGAGGCGCAGCGTGAAAATAGCTGGCAAAGAGAGTAAAGAGATATCACGAGTGCAAGGCCGGGTGAT
GAAAGGCGTGATGGTATTATTACTGGCTACAGGTTTAGCGGGCCATGCACAAGCCGCACCAGGCAACGGCAGTGCGGTTG
CGGCTACGGTTACCGCACCCACAGCGGCAACGTCAACCCCGTTACCTGCACCAGAAATTACCTCGGTTGCTGCAATACCG
GAATCAACACCAGAGTCAGTATTAACATCAGCATCAGCATTAACCTCAGAATCAATACCGGCCCCTATGGTTCAGCCCGT
TACGGCTCCAGTACCACAAAAGCTGGCGATGGATTTATCTGTCTGGGGTATGTATCAGAATGCGGACGTGGTTGTTAAAG
GCGTCATGATTGGTCTGGTGCTGGCTTCTATCGTCACTTGGACCATTCTGTTCTCTAAAGGGACTGAATTGTTCCGCGCT
CGTCGTCGGTTGCGCCAAGAGCATGAAGTGATTGGGGCCGTGACCGATCTTGATACCGCTTCGGAGCGAGCAGAAGATTT
TGGTCAAGGCAGCGTAAGCAGTTTGTTACTGCATGAAGCACTGAACGAGCGCCTGTTGTCGATAGAGTCAAATGACAATA
ATGGCATTAAAGAACGTACTGCTTTCCGTTTGGAGCGCCGGGTAGCCGCCATTGGCCGCCAAATGGGCAAAGGTAATGGC
TTCCTGGCAACAATCGGCGCAATTTCCCCCTTTGTCGGTTTGTTTGGTACGGTTTGGGGCATCATGAACAGCTTTATCGG
CATTGCCCACTCACAGACCACCAATCTGGCGGTTATCGCTCCAGGGATTGCCGAAGCGTTATTGGCAACGGCGTTAGGGC
TGGTGGCTGCGATCCCAGCGGTCGTTATTTATAATATCTTTGCTCGCCAGATCGGAAATTATCGCGCTCAAGTGGGTGAT
GTCGCGGCACAAGTGTTACTGCTGTTGAGCCGTGATTTGGATTTGGCCAGTAGCGCCGAAGTAAAGTCCCCTCGCCATCC
TCATCAATTACGAGCAGGGTGA

Upstream 100 bases:

>100_bases
TTCTTGCGCTCAAAAAAATCTTGCCAAATACTAATGATAATTACTATCAATCCGCTGTTTGTTTGATATGATCAAAAGCT
GATTTTGTCCTTAAATTGAC

Downstream 100 bases:

>100_bases
TTTATGGCAATGCGAATGAATGATTCCCTCGACGAGAGTGGAGAATTACACGAAATTAACGTGACGCCGTTTATTGATGT
CATGTTGGTGCTGCTGATTA

Product: TonB complex protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 353; Mature: 353

Protein sequence:

>353_residues
MHIGWRRSVKIAGKESKEISRVQGRVMKGVMVLLLATGLAGHAQAAPGNGSAVAATVTAPTAATSTPLPAPEITSVAAIP
ESTPESVLTSASALTSESIPAPMVQPVTAPVPQKLAMDLSVWGMYQNADVVVKGVMIGLVLASIVTWTILFSKGTELFRA
RRRLRQEHEVIGAVTDLDTASERAEDFGQGSVSSLLLHEALNERLLSIESNDNNGIKERTAFRLERRVAAIGRQMGKGNG
FLATIGAISPFVGLFGTVWGIMNSFIGIAHSQTTNLAVIAPGIAEALLATALGLVAAIPAVVIYNIFARQIGNYRAQVGD
VAAQVLLLLSRDLDLASSAEVKSPRHPHQLRAG

Sequences:

>Translated_353_residues
MHIGWRRSVKIAGKESKEISRVQGRVMKGVMVLLLATGLAGHAQAAPGNGSAVAATVTAPTAATSTPLPAPEITSVAAIP
ESTPESVLTSASALTSESIPAPMVQPVTAPVPQKLAMDLSVWGMYQNADVVVKGVMIGLVLASIVTWTILFSKGTELFRA
RRRLRQEHEVIGAVTDLDTASERAEDFGQGSVSSLLLHEALNERLLSIESNDNNGIKERTAFRLERRVAAIGRQMGKGNG
FLATIGAISPFVGLFGTVWGIMNSFIGIAHSQTTNLAVIAPGIAEALLATALGLVAAIPAVVIYNIFARQIGNYRAQVGD
VAAQVLLLLSRDLDLASSAEVKSPRHPHQLRAG
>Mature_353_residues
MHIGWRRSVKIAGKESKEISRVQGRVMKGVMVLLLATGLAGHAQAAPGNGSAVAATVTAPTAATSTPLPAPEITSVAAIP
ESTPESVLTSASALTSESIPAPMVQPVTAPVPQKLAMDLSVWGMYQNADVVVKGVMIGLVLASIVTWTILFSKGTELFRA
RRRLRQEHEVIGAVTDLDTASERAEDFGQGSVSSLLLHEALNERLLSIESNDNNGIKERTAFRLERRVAAIGRQMGKGNG
FLATIGAISPFVGLFGTVWGIMNSFIGIAHSQTTNLAVIAPGIAEALLATALGLVAAIPAVVIYNIFARQIGNYRAQVGD
VAAQVLLLLSRDLDLASSAEVKSPRHPHQLRAG

Specific function: Involved in the tonB-dependent energy-dependent transport of various receptor-bound substrates. Protects exbD from proteolytic degradation and functionally stabilizes tonB [H]

COG id: COG0811

COG function: function code U; Biopolymer transport proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the exbB/tolQ family [H]

Homologues:

Organism=Escherichia coli, GI1789381, Length=236, Percent_Identity=70.7627118644068, Blast_Score=340, Evalue=9e-95,
Organism=Escherichia coli, GI1786958, Length=235, Percent_Identity=31.4893617021277, Blast_Score=96, Evalue=4e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002898
- InterPro:   IPR014164 [H]

Pfam domain/function: PF01618 MotA_ExbB [H]

EC number: NA

Molecular weight: Translated: 37129; Mature: 37129

Theoretical pI: Translated: 10.06; Mature: 10.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHIGWRRSVKIAGKESKEISRVQGRVMKGVMVLLLATGLAGHAQAAPGNGSAVAATVTAP
CCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEECC
TAATSTPLPAPEITSVAAIPESTPESVLTSASALTSESIPAPMVQPVTAPVPQKLAMDLS
CCCCCCCCCCCCCCHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHH
VWGMYQNADVVVKGVMIGLVLASIVTWTILFSKGTELFRARRRLRQEHEVIGAVTDLDTA
HHEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCHHH
SERAEDFGQGSVSSLLLHEALNERLLSIESNDNNGIKERTAFRLERRVAAIGRQMGKGNG
HHHHHHHCCCHHHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCC
FLATIGAISPFVGLFGTVWGIMNSFIGIAHSQTTNLAVIAPGIAEALLATALGLVAAIPA
EEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHHHHHHHHHHH
VVIYNIFARQIGNYRAQVGDVAAQVLLLLSRDLDLASSAEVKSPRHPHQLRAG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MHIGWRRSVKIAGKESKEISRVQGRVMKGVMVLLLATGLAGHAQAAPGNGSAVAATVTAP
CCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEECC
TAATSTPLPAPEITSVAAIPESTPESVLTSASALTSESIPAPMVQPVTAPVPQKLAMDLS
CCCCCCCCCCCCCCHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHH
VWGMYQNADVVVKGVMIGLVLASIVTWTILFSKGTELFRARRRLRQEHEVIGAVTDLDTA
HHEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCHHH
SERAEDFGQGSVSSLLLHEALNERLLSIESNDNNGIKERTAFRLERRVAAIGRQMGKGNG
HHHHHHHCCCHHHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCC
FLATIGAISPFVGLFGTVWGIMNSFIGIAHSQTTNLAVIAPGIAEALLATALGLVAAIPA
EEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHHHHHHHHHHH
VVIYNIFARQIGNYRAQVGDVAAQVLLLLSRDLDLASSAEVKSPRHPHQLRAG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]