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The map label for this gene is yggW [H]

Identifier: 22127208

GI number: 22127208

Start: 3664225

End: 3665367

Strand: Direct

Name: yggW [H]

Synonym: y3332

Alternate gene names: 22127208

Gene position: 3664225-3665367 (Clockwise)

Preceding gene: 161484757

Following gene: 22127215

Centisome position: 79.64

GC content: 49.26

Gene sequence:

>1143_bases
ATGCGCTGCGCGATGCTTAAATTACCCCCGCTCAGTCTCTACATCCATATCCCTTGGTGCGTCCAGAAATGCCCTTATTG
TGATTTCAACTCACATGCGTTGAAAGGCGATGTCCCTCATCAGGAATATGTAGAGCACGTACTGGCGGATTTGGATGCTG
ACGTGCCTCTGGTGAGTGGCCGTGAAATCAGCACTATTTTTATTGGTGGCGGCACACCCAGCTTGCTGAGTGCAGAGGCC
ATGCAGCAACTACTTGATGGTGTCCGCGCGCGTTTGCCGGTTGCCAGTGACGCAGAGATCACCATGGAAGCCAACCCCGG
AGCGGTCGAAGCCGATCGCTTTAGCGGCTATCAGCGAGCGGGTATTAACCGCATATCCATTGGCGTCCAGAGCTTTAGCG
CACAGAAATTAACGCGGCTGGGGCGGATACATGGGCCAGATGAAGCAAGGCGGGCAGCAGAGCTGGCAACCTCACTGCAA
TTACGTAGCTTTAATCTAGATTTGATGCACGGTCTGCCTGATCAAACACTGGAAGAAGCATTGGATGATTTGCGTCAGGC
TATCGCCTTAAATCCACCACACTTATCTTGGTATCAGCTGACTATTGAGCCGAATACTGGCTTTAGTTCCCGGCCCCCAA
TCCTGCCCGATGACGATGCGTTATGGGATATTTTCCAGCAAGGTCATCAGCTACTCAGTGCCGCTGGTTATCTGCAATAT
GAAACCTCGGCCTATGCCAAGCCAGGTTACCAATGCCAGCATAATCTTAACTACTGGCGCTTTGGTGATTATCTGGGGAT
TGGCTGTGGGGCGCATGGCAAGATCACATTTAACGATGGGCGTATTTTACGGACCATAAAAACCAAACATCCACGTGGTT
TTATGCAGGGAAAATACTTGGATAAACAATATGAAGTGGCAGCAGTCGACCGGCCTTTTGAGTTCTTTATGAACCGCTTC
CGTTTGTTGGAAGCTGCCCCTCGGGCTGATTTCTATCACTTCACCGGGTTAACTGAGAGTACTATTCGCCCACAGTTAGA
TGAGGCAATAGCAAAAGAGTATTTAATCGAAACAACAGAATACTGGCAGATTACCGAAAAAGGAAAATTGTTCCTTAACT
CGCTACTGGAGCTATTTTTATAG

Upstream 100 bases:

>100_bases
ATTTTCTATGTACCCGCGCTGGGTAAAACCGCAGCGGAACTGACTCGTGAAGAAAAGCACGCGGTATCCCATCGTGGTCA
GGCCCTGAAATTGATGCTGG

Downstream 100 bases:

>100_bases
TTGTGATAGCTACGCTAATAATTGTGAAAGCTAGGTTAATAGTTGTGACAGCTAGGCTAAAAATGGCGATATTCCTAATC
CTTCGAGTGGCAGGAAGGCA

Product: coproporphyrinogen III oxidase

Products: Protoporphyrinogen IX; CO2; H2O

Alternate protein names: NA

Number of amino acids: Translated: 380; Mature: 380

Protein sequence:

>380_residues
MRCAMLKLPPLSLYIHIPWCVQKCPYCDFNSHALKGDVPHQEYVEHVLADLDADVPLVSGREISTIFIGGGTPSLLSAEA
MQQLLDGVRARLPVASDAEITMEANPGAVEADRFSGYQRAGINRISIGVQSFSAQKLTRLGRIHGPDEARRAAELATSLQ
LRSFNLDLMHGLPDQTLEEALDDLRQAIALNPPHLSWYQLTIEPNTGFSSRPPILPDDDALWDIFQQGHQLLSAAGYLQY
ETSAYAKPGYQCQHNLNYWRFGDYLGIGCGAHGKITFNDGRILRTIKTKHPRGFMQGKYLDKQYEVAAVDRPFEFFMNRF
RLLEAAPRADFYHFTGLTESTIRPQLDEAIAKEYLIETTEYWQITEKGKLFLNSLLELFL

Sequences:

>Translated_380_residues
MRCAMLKLPPLSLYIHIPWCVQKCPYCDFNSHALKGDVPHQEYVEHVLADLDADVPLVSGREISTIFIGGGTPSLLSAEA
MQQLLDGVRARLPVASDAEITMEANPGAVEADRFSGYQRAGINRISIGVQSFSAQKLTRLGRIHGPDEARRAAELATSLQ
LRSFNLDLMHGLPDQTLEEALDDLRQAIALNPPHLSWYQLTIEPNTGFSSRPPILPDDDALWDIFQQGHQLLSAAGYLQY
ETSAYAKPGYQCQHNLNYWRFGDYLGIGCGAHGKITFNDGRILRTIKTKHPRGFMQGKYLDKQYEVAAVDRPFEFFMNRF
RLLEAAPRADFYHFTGLTESTIRPQLDEAIAKEYLIETTEYWQITEKGKLFLNSLLELFL
>Mature_380_residues
MRCAMLKLPPLSLYIHIPWCVQKCPYCDFNSHALKGDVPHQEYVEHVLADLDADVPLVSGREISTIFIGGGTPSLLSAEA
MQQLLDGVRARLPVASDAEITMEANPGAVEADRFSGYQRAGINRISIGVQSFSAQKLTRLGRIHGPDEARRAAELATSLQ
LRSFNLDLMHGLPDQTLEEALDDLRQAIALNPPHLSWYQLTIEPNTGFSSRPPILPDDDALWDIFQQGHQLLSAAGYLQY
ETSAYAKPGYQCQHNLNYWRFGDYLGIGCGAHGKITFNDGRILRTIKTKHPRGFMQGKYLDKQYEVAAVDRPFEFFMNRF
RLLEAAPRADFYHFTGLTESTIRPQLDEAIAKEYLIETTEYWQITEKGKLFLNSLLELFL

Specific function: Unknown

COG id: COG0635

COG function: function code H; Coproporphyrinogen III oxidase and related Fe-S oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anaerobic coproporphyrinogen-III oxidase family [H]

Homologues:

Organism=Homo sapiens, GI8922911, Length=268, Percent_Identity=33.955223880597, Blast_Score=162, Evalue=4e-40,
Organism=Escherichia coli, GI1789325, Length=376, Percent_Identity=81.6489361702128, Blast_Score=655, Evalue=0.0,
Organism=Escherichia coli, GI87082341, Length=243, Percent_Identity=30.4526748971193, Blast_Score=121, Evalue=6e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR004559
- InterPro:   IPR010723
- InterPro:   IPR007197 [H]

Pfam domain/function: PF06969 HemN_C; PF04055 Radical_SAM [H]

EC number: 1.3.3.3

Molecular weight: Translated: 42866; Mature: 42866

Theoretical pI: Translated: 5.93; Mature: 5.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRCAMLKLPPLSLYIHIPWCVQKCPYCDFNSHALKGDVPHQEYVEHVLADLDADVPLVSG
CCEEEEECCCEEEEEECCHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEECC
REISTIFIGGGTPSLLSAEAMQQLLDGVRARLPVASDAEITMEANPGAVEADRFSGYQRA
CEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCHHHHCCHHHC
GINRISIGVQSFSAQKLTRLGRIHGPDEARRAAELATSLQLRSFNLDLMHGLPDQTLEEA
CCCEEEEEHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHEECCCHHHCCCCHHHHHHH
LDDLRQAIALNPPHLSWYQLTIEPNTGFSSRPPILPDDDALWDIFQQGHQLLSAAGYLQY
HHHHHHHHCCCCCCCEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCEEE
ETSAYAKPGYQCQHNLNYWRFGDYLGIGCGAHGKITFNDGRILRTIKTKHPRGFMQGKYL
CCCCCCCCCCCCCCCCCEEEECCEEEECCCCCCEEEECCCEEEEEEECCCCCCCCCCCCC
DKQYEVAAVDRPFEFFMNRFRLLEAAPRADFYHFTGLTESTIRPQLDEAIAKEYLIETTE
CCCEEEEECCCCHHHHHHHHHHHHCCCCCCEEEECCCCCHHCCHHHHHHHHHHHHHCCHH
YWQITEKGKLFLNSLLELFL
HEEECHHHHHHHHHHHHHHC
>Mature Secondary Structure
MRCAMLKLPPLSLYIHIPWCVQKCPYCDFNSHALKGDVPHQEYVEHVLADLDADVPLVSG
CCEEEEECCCEEEEEECCHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEECC
REISTIFIGGGTPSLLSAEAMQQLLDGVRARLPVASDAEITMEANPGAVEADRFSGYQRA
CEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCHHHHCCHHHC
GINRISIGVQSFSAQKLTRLGRIHGPDEARRAAELATSLQLRSFNLDLMHGLPDQTLEEA
CCCEEEEEHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHEECCCHHHCCCCHHHHHHH
LDDLRQAIALNPPHLSWYQLTIEPNTGFSSRPPILPDDDALWDIFQQGHQLLSAAGYLQY
HHHHHHHHCCCCCCCEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCEEE
ETSAYAKPGYQCQHNLNYWRFGDYLGIGCGAHGKITFNDGRILRTIKTKHPRGFMQGKYL
CCCCCCCCCCCCCCCCCEEEECCEEEECCCCCCEEEECCCEEEEEEECCCCCCCCCCCCC
DKQYEVAAVDRPFEFFMNRFRLLEAAPRADFYHFTGLTESTIRPQLDEAIAKEYLIETTE
CCCEEEEECCCCHHHHHHHHHHHHCCCCCCEEEECCCCCHHCCHHHHHHHHHHHHHCCHH
YWQITEKGKLFLNSLLELFL
HEEECHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Coproporphyrinogen III; O2; H+

Specific reaction: coproporphyrinogen-III + O2 + 2 H+ = protoporphyrinogen-IX + 2 CO2 + 2 H2O

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]