Click here to switch to the map view.

The map label for this gene is yadA [H]

Identifier: 22127163

GI number: 22127163

Start: 3617319

End: 3619244

Strand: Reverse

Name: yadA [H]

Synonym: y3288

Alternate gene names: 22127163

Gene position: 3619244-3617319 (Counterclockwise)

Preceding gene: 22127165

Following gene: 22127162

Centisome position: 78.67

GC content: 54.31

Gene sequence:

>1926_bases
GTGGGGCCTATAACTAGTCCGAATTGTAATACTCCATCTATTGGGATTATTAATACAAATGCGGGGCAGCTATTTGTTGG
TGGAACGGGGGCTGCGGTATCGGGAACATTAGGCCCTACTTTTTGGACAGGGACATTTGCTACACCGGTCGGCACCAGTA
ATACCGCAACTGCATACGGTATGGTCGTTCAAAGCGGTGGTGCGTACATCACGGGTAATACTTACGTACAAGGTGGGTTA
TTCTTGAATGGGCAAAAAGCGACCAATCTTGCCCCTGCGACGATTTCATCTACCTCTACCGATGCGGTAGTTGGTAGCCA
GCTTTATAATCTGGTCCAAGATGGAACCCGCTATTTCCATGCTAACTCAGTGAATCCAACAGACTCACTGGCCTCTGGCC
TGGAAACCATTGCTGTCGGGCCAGCGACAGTGGTCAGTGGAGATAACGGTGTTGGCATTGGTAACACCGCCCTTGTCGGG
GCGGCAGCAACGGGGGGAATTGCAATAGGTTTCGGTACTCAGGTGACAGCTGCCGGGGCTACGGCCATCGGTTCCGCAGC
GCAGGCTCAAGGGGCGCAATCTCTGGCGTTAGGCGCGGGGGCGGTGACCAGCCAGGCAAACAGTATCGCGTTGGGGGCTG
CTTCGATCAATACGGTCGGCGCTCAGAGCAGTTACAGTGCTTATGCACTAACGGCTCCGCAGGCATCGGTGGGGGAGTTA
GGGATTGGCACCGCATTGGGTAATCGTAAGATTACCGGTGTCGCAGCTGGATCGGCGAGTTCTGATGCGGTCAATGTTGC
TCAGTTGACTGCTGTTGGTGATCAGGTGCAGCAGAATACCGCGAACATCACCAGCCTGGGTGGCCGGGTTACCACCATTG
AGGGGAGCATGGCCAGCATCGCCAATGGTGGCGGTGTGAAGTATTTCCATGCCAACTCGACTCAGCCTGACTCGGTAGCC
AGTGGTACCAATTCGGTGGCCATCGGGCCTGCTTCTCTGGCTTCGGGTAATGCTGCTTTGGCTTCGGGGGCAGGGGCGGT
GGCGATAGGGGATGGTGCTGCCGCCAGCGCGGACGGCAGTGTTGCCATTGGTCAGGGATCTGGTGATAACGGGCGTGGCG
TAGAGAACTACATCGGTAAGTATTCCAATGCGAGTAACACCAGCTCGGGTACCGTATCAGTGGGTAATACTGCTACTGGA
GAAACCCGGACGGTCAGCAATGTTGCCGATGGGCTGCAGGCCACCGATGCGGTCAATTTGCGACAACTCGATGGTATTGC
TGCCTCTATCGTCGTCGTCGAAAACAACGTTTCTGGGCTCCAGAATGGTACCGATGGTATGTTTCAGGTGAATAATAGTA
GCGGTCTTGCCAAGCCATCCGCAACCGGTGCTAATTCAGCAACTGGTGGTGCCGGTTCTGTGGCTTCCGGCAATAACAGT
ACCGCGTTTGGCTCAGGTGCTAAAGCAACAGCGGCAAACAGTGCAGCCTTGGGGGCTAACTCAGTAGCTGATCGGGCAAA
CAGTGTTTCGGTAGGCTCTGTTGGTAATGAACGGCAGATCACCAACGTCGCCCCCGCAACTCAGGGAACCGACGCGGTGA
ACTTCGATCAACTTAAGAGCATTTCCAATCAAACTAATGCTTACACGAACCAACGTTATTCCGAGCTGAAGCAGGATCTG
AGGAAACAAAATAGCGTGTTGAGTGCAGGGATAGCTAGCGCAATGTCTATGGCGAGCTTGACACAACCATATACTTCGGG
TTCCAGCATGACCACTATCGGCGCGGCCAGTTACCGTGGTCAATCGGCTCTGTCGCTAGGGGTATCGAGTATTTCTGACA
GCGGGAGATGGGTCAGCAAACTACAGGCATCCTCTAACACTCAAGGTGATTTTGGGATTGGTGTCGGTGTAGGGTATCAG
TGGTAA

Upstream 100 bases:

>100_bases
CTATAGTGATGATTTATTTATCCCTGGCACCGCAACTTCTCAGCTTTATGTGAATAATGCTGATGATCAGTCTTGTTATG
CCATTATGGATGGGCCGTCG

Downstream 100 bases:

>100_bases
AGAGCGCGTTACGCCAACGCTGAATGCTATTCAGGCTGTCACTAACGGGTTGTAGGGTGTTTTGTACAACCCGATTCTCG
CTCTTGGGCATCAAAGGATC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 641; Mature: 640

Protein sequence:

>641_residues
MGPITSPNCNTPSIGIINTNAGQLFVGGTGAAVSGTLGPTFWTGTFATPVGTSNTATAYGMVVQSGGAYITGNTYVQGGL
FLNGQKATNLAPATISSTSTDAVVGSQLYNLVQDGTRYFHANSVNPTDSLASGLETIAVGPATVVSGDNGVGIGNTALVG
AAATGGIAIGFGTQVTAAGATAIGSAAQAQGAQSLALGAGAVTSQANSIALGAASINTVGAQSSYSAYALTAPQASVGEL
GIGTALGNRKITGVAAGSASSDAVNVAQLTAVGDQVQQNTANITSLGGRVTTIEGSMASIANGGGVKYFHANSTQPDSVA
SGTNSVAIGPASLASGNAALASGAGAVAIGDGAAASADGSVAIGQGSGDNGRGVENYIGKYSNASNTSSGTVSVGNTATG
ETRTVSNVADGLQATDAVNLRQLDGIAASIVVVENNVSGLQNGTDGMFQVNNSSGLAKPSATGANSATGGAGSVASGNNS
TAFGSGAKATAANSAALGANSVADRANSVSVGSVGNERQITNVAPATQGTDAVNFDQLKSISNQTNAYTNQRYSELKQDL
RKQNSVLSAGIASAMSMASLTQPYTSGSSMTTIGAASYRGQSALSLGVSSISDSGRWVSKLQASSNTQGDFGIGVGVGYQ
W

Sequences:

>Translated_641_residues
MGPITSPNCNTPSIGIINTNAGQLFVGGTGAAVSGTLGPTFWTGTFATPVGTSNTATAYGMVVQSGGAYITGNTYVQGGL
FLNGQKATNLAPATISSTSTDAVVGSQLYNLVQDGTRYFHANSVNPTDSLASGLETIAVGPATVVSGDNGVGIGNTALVG
AAATGGIAIGFGTQVTAAGATAIGSAAQAQGAQSLALGAGAVTSQANSIALGAASINTVGAQSSYSAYALTAPQASVGEL
GIGTALGNRKITGVAAGSASSDAVNVAQLTAVGDQVQQNTANITSLGGRVTTIEGSMASIANGGGVKYFHANSTQPDSVA
SGTNSVAIGPASLASGNAALASGAGAVAIGDGAAASADGSVAIGQGSGDNGRGVENYIGKYSNASNTSSGTVSVGNTATG
ETRTVSNVADGLQATDAVNLRQLDGIAASIVVVENNVSGLQNGTDGMFQVNNSSGLAKPSATGANSATGGAGSVASGNNS
TAFGSGAKATAANSAALGANSVADRANSVSVGSVGNERQITNVAPATQGTDAVNFDQLKSISNQTNAYTNQRYSELKQDL
RKQNSVLSAGIASAMSMASLTQPYTSGSSMTTIGAASYRGQSALSLGVSSISDSGRWVSKLQASSNTQGDFGIGVGVGYQ
W
>Mature_640_residues
GPITSPNCNTPSIGIINTNAGQLFVGGTGAAVSGTLGPTFWTGTFATPVGTSNTATAYGMVVQSGGAYITGNTYVQGGLF
LNGQKATNLAPATISSTSTDAVVGSQLYNLVQDGTRYFHANSVNPTDSLASGLETIAVGPATVVSGDNGVGIGNTALVGA
AATGGIAIGFGTQVTAAGATAIGSAAQAQGAQSLALGAGAVTSQANSIALGAASINTVGAQSSYSAYALTAPQASVGELG
IGTALGNRKITGVAAGSASSDAVNVAQLTAVGDQVQQNTANITSLGGRVTTIEGSMASIANGGGVKYFHANSTQPDSVAS
GTNSVAIGPASLASGNAALASGAGAVAIGDGAAASADGSVAIGQGSGDNGRGVENYIGKYSNASNTSSGTVSVGNTATGE
TRTVSNVADGLQATDAVNLRQLDGIAASIVVVENNVSGLQNGTDGMFQVNNSSGLAKPSATGANSATGGAGSVASGNNST
AFGSGAKATAANSAALGANSVADRANSVSVGSVGNERQITNVAPATQGTDAVNFDQLKSISNQTNAYTNQRYSELKQDLR
KQNSVLSAGIASAMSMASLTQPYTSGSSMTTIGAASYRGQSALSLGVSSISDSGRWVSKLQASSNTQGDFGIGVGVGYQW

Specific function: Collagen-binding outer membrane protein forming a fibrillar matrix on the bacterial cell surface. Promotes initial attachment and invasion of eukaryotic cells. Also protects the bacteria by being responsible for agglutination, serum resistance, complement

COG id: COG5295

COG function: function code UW; Autotransporter adhesin

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the autotransporter-2 (TC 1.B.40) / oligomeric coiled-coil adhesin (Oca) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008640
- InterPro:   IPR008635
- InterPro:   IPR008126
- InterPro:   IPR005594 [H]

Pfam domain/function: PF05658 Hep_Hag; PF05662 HIM; PF03895 YadA [H]

EC number: NA

Molecular weight: Translated: 62094; Mature: 61963

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGPITSPNCNTPSIGIINTNAGQLFVGGTGAAVSGTLGPTFWTGTFATPVGTSNTATAYG
CCCCCCCCCCCCEEEEEECCCCEEEECCCCCEEECCCCCCEECCCEECCCCCCCCCEEEE
MVVQSGGAYITGNTYVQGGLFLNGQKATNLAPATISSTSTDAVVGSQLYNLVQDGTRYFH
EEEECCCCEEECCEEEECCEEECCCCCCCCCCCEECCCCCHHHHHHHHHHHHHCCCEEEE
ANSVNPTDSLASGLETIAVGPATVVSGDNGVGIGNTALVGAAATGGIAIGFGTQVTAAGA
CCCCCCHHHHHHCCCEEECCCEEEEECCCCCCCCCCEEEEEECCCCEEEECCCEEEECCH
TAIGSAAQAQGAQSLALGAGAVTSQANSIALGAASINTVGAQSSYSAYALTAPQASVGEL
HHHCCHHHHCCCCCEEECCCHHHCCCCEEEEECCCCCCCCCCCCCCEEEEECCCCCCCCC
GIGTALGNRKITGVAAGSASSDAVNVAQLTAVGDQVQQNTANITSLGGRVTTIEGSMASI
CCEEECCCCEEEEEECCCCCCCCEEHHHHHHHHHHHHHCCCCHHHCCCEEEEECCCHHHH
ANGGGVKYFHANSTQPDSVASGTNSVAIGPASLASGNAALASGAGAVAIGDGAAASADGS
CCCCCEEEEECCCCCCCHHHCCCCCEEECCHHHCCCCEEEECCCCEEEECCCCCCCCCCC
VAIGQGSGDNGRGVENYIGKYSNASNTSSGTVSVGNTATGETRTVSNVADGLQATDAVNL
EEEECCCCCCCCCHHHHHHCCCCCCCCCCCEEEECCCCCCCCEEHHHHHCCHHHCCCCCH
RQLDGIAASIVVVENNVSGLQNGTDGMFQVNNSSGLAKPSATGANSATGGAGSVASGNNS
HHHCCCEEEEEEEECCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
TAFGSGAKATAANSAALGANSVADRANSVSVGSVGNERQITNVAPATQGTDAVNFDQLKS
CCCCCCCCCCCCCCHHCCCCHHHHCCCCEEECCCCCCCEEEECCCCCCCCCCCCHHHHHH
ISNQTNAYTNQRYSELKQDLRKQNSVLSAGIASAMSMASLTQPYTSGSSMTTIGAASYRG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCC
QSALSLGVSSISDSGRWVSKLQASSNTQGDFGIGVGVGYQW
CHHHHHHHHHCCCCCHHHHHHHHCCCCCCCEEEEECCCCCC
>Mature Secondary Structure 
GPITSPNCNTPSIGIINTNAGQLFVGGTGAAVSGTLGPTFWTGTFATPVGTSNTATAYG
CCCCCCCCCCCEEEEEECCCCEEEECCCCCEEECCCCCCEECCCEECCCCCCCCCEEEE
MVVQSGGAYITGNTYVQGGLFLNGQKATNLAPATISSTSTDAVVGSQLYNLVQDGTRYFH
EEEECCCCEEECCEEEECCEEECCCCCCCCCCCEECCCCCHHHHHHHHHHHHHCCCEEEE
ANSVNPTDSLASGLETIAVGPATVVSGDNGVGIGNTALVGAAATGGIAIGFGTQVTAAGA
CCCCCCHHHHHHCCCEEECCCEEEEECCCCCCCCCCEEEEEECCCCEEEECCCEEEECCH
TAIGSAAQAQGAQSLALGAGAVTSQANSIALGAASINTVGAQSSYSAYALTAPQASVGEL
HHHCCHHHHCCCCCEEECCCHHHCCCCEEEEECCCCCCCCCCCCCCEEEEECCCCCCCCC
GIGTALGNRKITGVAAGSASSDAVNVAQLTAVGDQVQQNTANITSLGGRVTTIEGSMASI
CCEEECCCCEEEEEECCCCCCCCEEHHHHHHHHHHHHHCCCCHHHCCCEEEEECCCHHHH
ANGGGVKYFHANSTQPDSVASGTNSVAIGPASLASGNAALASGAGAVAIGDGAAASADGS
CCCCCEEEEECCCCCCCHHHCCCCCEEECCHHHCCCCEEEECCCCEEEECCCCCCCCCCC
VAIGQGSGDNGRGVENYIGKYSNASNTSSGTVSVGNTATGETRTVSNVADGLQATDAVNL
EEEECCCCCCCCCHHHHHHCCCCCCCCCCCEEEECCCCCCCCEEHHHHHCCHHHCCCCCH
RQLDGIAASIVVVENNVSGLQNGTDGMFQVNNSSGLAKPSATGANSATGGAGSVASGNNS
HHHCCCEEEEEEEECCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
TAFGSGAKATAANSAALGANSVADRANSVSVGSVGNERQITNVAPATQGTDAVNFDQLKS
CCCCCCCCCCCCCCHHCCCCHHHHCCCCEEECCCCCCCEEEECCCCCCCCCCCCHHHHHH
ISNQTNAYTNQRYSELKQDLRKQNSVLSAGIASAMSMASLTQPYTSGSSMTTIGAASYRG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCC
QSALSLGVSSISDSGRWVSKLQASSNTQGDFGIGVGVGYQW
CHHHHHHHHHCCCCCHHHHHHHHCCCCCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 14527656; 2592347 [H]