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The map label for this gene is mocB [H]

Identifier: 22127121

GI number: 22127121

Start: 3578086

End: 3579108

Strand: Direct

Name: mocB [H]

Synonym: y3245

Alternate gene names: 22127121

Gene position: 3578086-3579108 (Clockwise)

Preceding gene: 22127120

Following gene: 22127122

Centisome position: 77.77

GC content: 47.51

Gene sequence:

>1023_bases
TTGAACGCACCAGGAGCTTTTATGAAAAAAACAATGCTACAAACTCTGCTTGCTGCAACGCTGATACTTTCCTTTGCGGC
ATCAGTGCAAGCAGCCCCAGTAAAAATTGCTATTTTGATGTATGGCATGAAAGCTGAATTTGTTCAGCTAATGGAAAAGT
CAGCCAAAGAACATCCTGCGGTAACACAGGGGTTAACTACGTTGACTCTTTTCGATGGCCGCTATGATCCGTTAGTCCAG
AATAACCAAGCCGAAACTGCAATACGTACCCGTTATGATGCCATTATTATTGTTCCGATAGATTTTGAAGCCAACGTAGA
TGTGGTCACGATGGCGAATAAAGCCAATATTCCGGTGATTGTCGCCAATGCCCGCTTGAATACAGATAAAGCGACCAGTG
GAATCTTCTCTGATGATGTTCAAGGGGGTTATCTGGAAGCCAAAGCGGTGCTGGATAAAATGCAGTGCCAGGGCAATGTG
GTCGTTATTGAAGGGCCAATCGGGCAATCCGCACAGATCCAGCGTGGCCAGGGCAACGATAAAGCGATTGCTGAATGTGG
GCCGGGGAAAATCAACGTACTGGAACGTAAAACCGCCAACTGGTCACGTGCCGAAGCGATGCCGTTGATGGAGAACTGGC
TACAAAAACATCGTGGCAAGATTAATGGTGTGATCGGGCAAAATGACGAAATGGCGTTGGGTGCCATTGAAGCGATCAAG
AGCGCCGGCCTGAATGTCCAAGATTTTGCCATTGCCGGTATCGATGGTGTCTCTGATGCGATCCGGGCGGTTAAACAAGG
TGAAATGATGTCTATCCTGCAAGATGGCCAGGCTCAAATACAAGGGGCTATTGATATCGCTATGCGTTCGGTACAAGGAG
AGCGTTACCAGCCTATGTCAACGATCTGGCAGCAATATCAGGGAAAAATGGATTGGCAACAAGGGACGGCAAAAATGTAT
GAAGTACCTTGGACTGAAGTAACGCCACAAAATGCGGACGAGCTGCTAAAGATGCGTCAGTAA

Upstream 100 bases:

>100_bases
GTCAATACCAGTAAGTCATTCGGGTCATTGAGCGTAGCCAACACACATGCCGTTTGATGTATGACGGGTATATACCGTAA
CTCTATAATTTTAAAGTAAG

Downstream 100 bases:

>100_bases
GAGAGATGATCGCTATCGCCCCCGGCAGCGGCAAAATCTGCTGTCGGGTTTGAGGGTAAATCCCCCTAAAAACCGGAGTA
TTCATTGAATCTGCGCTCGA

Product: sugar-binding periplasmic protein

Products: ADP; phosphate; ribose [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 340; Mature: 340

Protein sequence:

>340_residues
MNAPGAFMKKTMLQTLLAATLILSFAASVQAAPVKIAILMYGMKAEFVQLMEKSAKEHPAVTQGLTTLTLFDGRYDPLVQ
NNQAETAIRTRYDAIIIVPIDFEANVDVVTMANKANIPVIVANARLNTDKATSGIFSDDVQGGYLEAKAVLDKMQCQGNV
VVIEGPIGQSAQIQRGQGNDKAIAECGPGKINVLERKTANWSRAEAMPLMENWLQKHRGKINGVIGQNDEMALGAIEAIK
SAGLNVQDFAIAGIDGVSDAIRAVKQGEMMSILQDGQAQIQGAIDIAMRSVQGERYQPMSTIWQQYQGKMDWQQGTAKMY
EVPWTEVTPQNADELLKMRQ

Sequences:

>Translated_340_residues
MNAPGAFMKKTMLQTLLAATLILSFAASVQAAPVKIAILMYGMKAEFVQLMEKSAKEHPAVTQGLTTLTLFDGRYDPLVQ
NNQAETAIRTRYDAIIIVPIDFEANVDVVTMANKANIPVIVANARLNTDKATSGIFSDDVQGGYLEAKAVLDKMQCQGNV
VVIEGPIGQSAQIQRGQGNDKAIAECGPGKINVLERKTANWSRAEAMPLMENWLQKHRGKINGVIGQNDEMALGAIEAIK
SAGLNVQDFAIAGIDGVSDAIRAVKQGEMMSILQDGQAQIQGAIDIAMRSVQGERYQPMSTIWQQYQGKMDWQQGTAKMY
EVPWTEVTPQNADELLKMRQ
>Mature_340_residues
MNAPGAFMKKTMLQTLLAATLILSFAASVQAAPVKIAILMYGMKAEFVQLMEKSAKEHPAVTQGLTTLTLFDGRYDPLVQ
NNQAETAIRTRYDAIIIVPIDFEANVDVVTMANKANIPVIVANARLNTDKATSGIFSDDVQGGYLEAKAVLDKMQCQGNV
VVIEGPIGQSAQIQRGQGNDKAIAECGPGKINVLERKTANWSRAEAMPLMENWLQKHRGKINGVIGQNDEMALGAIEAIK
SAGLNVQDFAIAGIDGVSDAIRAVKQGEMMSILQDGQAQIQGAIDIAMRSVQGERYQPMSTIWQQYQGKMDWQQGTAKMY
EVPWTEVTPQNADELLKMRQ

Specific function: Involved in rhizopine (L-3-O-methyl-scyllo-inosamine) catabolism. Could be involved in its high affinity transport [H]

COG id: COG1879

COG function: function code G; ABC-type sugar transport system, periplasmic component

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 2 family [H]

Homologues:

Organism=Escherichia coli, GI1790192, Length=294, Percent_Identity=31.2925170068027, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1788473, Length=352, Percent_Identity=27.5568181818182, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1790674, Length=209, Percent_Identity=29.1866028708134, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1789990, Length=210, Percent_Identity=28.5714285714286, Blast_Score=61, Evalue=9e-11,

Paralogues:

None

Copy number: 3940 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5900 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). 1520 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001761 [H]

Pfam domain/function: PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 37073; Mature: 37073

Theoretical pI: Translated: 5.22; Mature: 5.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
5.3 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
5.3 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAPGAFMKKTMLQTLLAATLILSFAASVQAAPVKIAILMYGMKAEFVQLMEKSAKEHPA
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCHHHHHHHHHHHHHCCCC
VTQGLTTLTLFDGRYDPLVQNNQAETAIRTRYDAIIIVPIDFEANVDVVTMANKANIPVI
HHHCCEEEEEECCCCCCCCCCCCHHHHHHHHCCEEEEEEECCCCCCEEEEECCCCCCCEE
VANARLNTDKATSGIFSDDVQGGYLEAKAVLDKMQCQGNVVVIEGPIGQSAQIQRGQGND
EEECEECCCHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCEEECCCCCC
KAIAECGPGKINVLERKTANWSRAEAMPLMENWLQKHRGKINGVIGQNDEMALGAIEAIK
CEEEECCCCCEEEEECCCCCCCHHHCCHHHHHHHHHHCCCEECCCCCCCCHHHHHHHHHH
SAGLNVQDFAIAGIDGVSDAIRAVKQGEMMSILQDGQAQIQGAIDIAMRSVQGERYQPMS
HCCCCCHHEEEECCCCHHHHHHHHHCCHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCHHH
TIWQQYQGKMDWQQGTAKMYEVPWTEVTPQNADELLKMRQ
HHHHHHCCCCCHHCCCCEEEECCCCCCCCCCHHHHHHHCC
>Mature Secondary Structure
MNAPGAFMKKTMLQTLLAATLILSFAASVQAAPVKIAILMYGMKAEFVQLMEKSAKEHPA
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCHHHHHHHHHHHHHCCCC
VTQGLTTLTLFDGRYDPLVQNNQAETAIRTRYDAIIIVPIDFEANVDVVTMANKANIPVI
HHHCCEEEEEECCCCCCCCCCCCHHHHHHHHCCEEEEEEECCCCCCEEEEECCCCCCCEE
VANARLNTDKATSGIFSDDVQGGYLEAKAVLDKMQCQGNVVVIEGPIGQSAQIQRGQGND
EEECEECCCHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCEEECCCCCC
KAIAECGPGKINVLERKTANWSRAEAMPLMENWLQKHRGKINGVIGQNDEMALGAIEAIK
CEEEECCCCCEEEEECCCCCCCHHHCCHHHHHHHHHHCCCEECCCCCCCCHHHHHHHHHH
SAGLNVQDFAIAGIDGVSDAIRAVKQGEMMSILQDGQAQIQGAIDIAMRSVQGERYQPMS
HCCCCCHHEEEECCCCHHHHHHHHHCCHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCHHH
TIWQQYQGKMDWQQGTAKMYEVPWTEVTPQNADELLKMRQ
HHHHHHCCCCCHHCCCCEEEECCCCCCCCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; ribose [Periplasm]; H2O [C]

Specific reaction: ATP + ribose [Periplasm] + H2O = ADP + phosphate + ribose [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7845353 [H]