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The map label for this gene is agaD [H]

Identifier: 22127097

GI number: 22127097

Start: 3546026

End: 3546862

Strand: Direct

Name: agaD [H]

Synonym: y3221

Alternate gene names: 22127097

Gene position: 3546026-3546862 (Clockwise)

Preceding gene: 22127096

Following gene: 22127098

Centisome position: 77.07

GC content: 50.54

Gene sequence:

>837_bases
ATGGCATCTGATATCACCGTAGATAAAGACCACACGGCAAAAGCGAAAACGGACAGCCTGGTGGACAAAATTGATTCCTA
TCAGGATCTTGAAGTTCGTAAAGTGGTTACCCGTAAAGATCTGTGGAAGTGCGCCATCCGTGGCCTGTTCATGGAAGGTA
ACTTTAACTTCGAACGTATGCAAGCCGGTGGTTTTGCTTATTCGATGATCCCCGCGTTGAAGAAAATCCACGGTAACAAC
CGTGCAGATTTGGCGAAATCGCTAAAGAACCATTTGCAGTTCTTTAATGCCAGTCCAAAGCTGTTCACCTTCCTGTTAGG
CACTGCGGTGGCGATGGAAGAGAACAAAGAAAAGCCCTCAATGATCAACGTAATGAAAGTTGCGGGCATGGGGCCAACAG
GCGGTATCGGCGATGCCATTGACCACATGACGCTGATGCCACTGACGCTGGCGCTGGGGGCTTCTATTGCGATTGAAGGC
TCCATCGCTGGCCCATTTGTGTTCTTCATTCTGTACCAGACTGTGCACTTCTTGGTCTATTTCGGCCTGATGTTTATGGG
CTACCGCGCGGGCACGGCGGCAATGGTGAACATGGGGGATGCCACGGAGAAACTGGCAAAAGCCGCCAATATCATGGGTA
TCTTTGTTATCGGCGCGTTGTGCGCCACCTTTATCAGGCTACAAACTACCGCGGCGATAGATCTTGGCGGGAAAACAGTG
GAGCTACAAACCGCCCTGTTTGACAAGATCATGCCGAATTTACTCCCGCTGGCATTGGTGTTCTTTATGTTCAAGATGGT
GAAAGGCACGGGTTTCTGGGCGAACCACCGGTGTTGA

Upstream 100 bases:

>100_bases
GGTGCTGCTGTTGCTGTCCTGTACTACTTCTTCAGTGGCAACAATAACGGCAGCAATAACAACGGTAACAACACCAACAA
ACAACCAGAGGATTTCGAAG

Downstream 100 bases:

>100_bases
TTTTCTCCACGCTGGCGGCCGGGGTCGTCGGTCATCTGCTGGGCATTGTCTAACCGTTATCGCCATCGCCGCATCGTGGC
TTTGCATGATGCGGCGTAAC

Product: PTS permease

Products: NA

Alternate protein names: EIID-Aga; PTS system N-acetylgalactosamine-specific EIID component [H]

Number of amino acids: Translated: 278; Mature: 277

Protein sequence:

>278_residues
MASDITVDKDHTAKAKTDSLVDKIDSYQDLEVRKVVTRKDLWKCAIRGLFMEGNFNFERMQAGGFAYSMIPALKKIHGNN
RADLAKSLKNHLQFFNASPKLFTFLLGTAVAMEENKEKPSMINVMKVAGMGPTGGIGDAIDHMTLMPLTLALGASIAIEG
SIAGPFVFFILYQTVHFLVYFGLMFMGYRAGTAAMVNMGDATEKLAKAANIMGIFVIGALCATFIRLQTTAAIDLGGKTV
ELQTALFDKIMPNLLPLALVFFMFKMVKGTGFWANHRC

Sequences:

>Translated_278_residues
MASDITVDKDHTAKAKTDSLVDKIDSYQDLEVRKVVTRKDLWKCAIRGLFMEGNFNFERMQAGGFAYSMIPALKKIHGNN
RADLAKSLKNHLQFFNASPKLFTFLLGTAVAMEENKEKPSMINVMKVAGMGPTGGIGDAIDHMTLMPLTLALGASIAIEG
SIAGPFVFFILYQTVHFLVYFGLMFMGYRAGTAAMVNMGDATEKLAKAANIMGIFVIGALCATFIRLQTTAAIDLGGKTV
ELQTALFDKIMPNLLPLALVFFMFKMVKGTGFWANHRC
>Mature_277_residues
ASDITVDKDHTAKAKTDSLVDKIDSYQDLEVRKVVTRKDLWKCAIRGLFMEGNFNFERMQAGGFAYSMIPALKKIHGNNR
ADLAKSLKNHLQFFNASPKLFTFLLGTAVAMEENKEKPSMINVMKVAGMGPTGGIGDAIDHMTLMPLTLALGASIAIEGS
IAGPFVFFILYQTVHFLVYFGLMFMGYRAGTAAMVNMGDATEKLAKAANIMGIFVIGALCATFIRLQTTAAIDLGGKTVE
LQTALFDKIMPNLLPLALVFFMFKMVKGTGFWANHRC

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system i

COG id: COG3716

COG function: function code G; Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIID domain [H]

Homologues:

Organism=Escherichia coli, GI1789529, Length=235, Percent_Identity=37.8723404255319, Blast_Score=177, Evalue=6e-46,
Organism=Escherichia coli, GI1788122, Length=250, Percent_Identity=37.6, Blast_Score=153, Evalue=1e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004704
- InterPro:   IPR018405 [H]

Pfam domain/function: PF03613 EIID-AGA [H]

EC number: NA

Molecular weight: Translated: 30459; Mature: 30328

Theoretical pI: Translated: 9.57; Mature: 9.57

Prosite motif: PS51108 PTS_EIID

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
6.5 %Met     (Translated Protein)
7.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
6.1 %Met     (Mature Protein)
7.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASDITVDKDHTAKAKTDSLVDKIDSYQDLEVRKVVTRKDLWKCAIRGLFMEGNFNFERM
CCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHEEECCCCCHHHH
QAGGFAYSMIPALKKIHGNNRADLAKSLKNHLQFFNASPKLFTFLLGTAVAMEENKEKPS
HCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCH
MINVMKVAGMGPTGGIGDAIDHMTLMPLTLALGASIAIEGSIAGPFVFFILYQTVHFLVY
HHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHHH
FGLMFMGYRAGTAAMVNMGDATEKLAKAANIMGIFVIGALCATFIRLQTTAAIDLGGKTV
HHHHHHHHCCCCHHEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCEE
ELQTALFDKIMPNLLPLALVFFMFKMVKGTGFWANHRC
EHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
ASDITVDKDHTAKAKTDSLVDKIDSYQDLEVRKVVTRKDLWKCAIRGLFMEGNFNFERM
CCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHEEECCCCCHHHH
QAGGFAYSMIPALKKIHGNNRADLAKSLKNHLQFFNASPKLFTFLLGTAVAMEENKEKPS
HCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCH
MINVMKVAGMGPTGGIGDAIDHMTLMPLTLALGASIAIEGSIAGPFVFFILYQTVHFLVY
HHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHHH
FGLMFMGYRAGTAAMVNMGDATEKLAKAANIMGIFVIGALCATFIRLQTTAAIDLGGKTV
HHHHHHHHCCCCHHEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCEE
ELQTALFDKIMPNLLPLALVFFMFKMVKGTGFWANHRC
EHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10931310; 9278503; 8932697 [H]