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The map label for this gene is agaZ [H]

Identifier: 22127093

GI number: 22127093

Start: 3542225

End: 3543523

Strand: Direct

Name: agaZ [H]

Synonym: y3217

Alternate gene names: 22127093

Gene position: 3542225-3543523 (Clockwise)

Preceding gene: 22127092

Following gene: 22127094

Centisome position: 76.99

GC content: 49.42

Gene sequence:

>1299_bases
ATGCATCCTTTAGAAAAACTGGTTCAGCGCCATAAAGCCGGGGAACAAATTGGGATTTACTCAGTTTGTTCTGCCCATCC
TCTTGTCATTGAAGCTGCGCTGGAGCAAGCGTTAGAAAATGACTCAGAACTGTTAATCGAAGCCACCTCTAATCAGGTTG
ACCAATTTGGTGGCTACACCGGTATGACGCCGGTTGATTTTCGTGATTACGTTTTTGCTAAAGCTGATGCTCTGCATTTC
CCTCTCGAAAAACTCATTTTAGGCGGCGACCATTTAGGACCAAACCGTTGGCAGCACTTGCCTGCCAACGAAGCCATGGC
GCATGCCGATGATCTGATCGCGGCGTATGTCGCGGCGGGCTTCAAAAAAATTCACCTCGATTGCAGCATGTCCTGCGCAG
ATGATCCCGTTCCCCTCTCCGATGAAATTGTAGCCGAGCGTGCTGCACGTCTGGCCGCCATTGCAGAAGCCACAGAATAT
CAACACTTCAATACACACACCGCCGTTTATGTCATCGGGACAGAAGTGCCTATCCCTGGTGGCGCGACCGAAGAGTTGGA
TGAAATCGAAGTCACCTCACCAGAAGCCGCGCGTAAAACGATTGAATGCCACCAAAAAGCATTTGAGAAATCAGGTGTTG
CTGAGTGCTGGCCACGGGTGATTGGTCTGGTCGTGCAGCCTGGTGTTGAGTTTGATCACACCGGTGTGATTGATTTCTGT
CCAGAGAAAGCCCATGAACTCAGTAAAGTCATGGATGAATACGATTATCAGGTATTCGAAGCCCACTCCACCGATTATCA
GACCGATGATGCCTATCGCGCACTGGTTAAAGGCCATTTTGCCATTCTGAAAGTAGGCCCGGCGCTGACATTTGCTCTGC
GTGAAGCCCTGTTCAGTTTATGTCATATCGAAGAAGAGTTATTCCCGGCAGAGCAGTGCTCCCGCCTCCGTCAGGTGATG
GAAGACGTAATGCTGAAATCGCCGGAATACTGGAAGAGATATTACCTCGGTGATACTGAGCAAGTGCGCTTAGCCCGCGT
TTACAGTTTCAGTGACCGCATGCGCTATTACTGGCCAATGGAAGCCGTGCAGGCTGCACAAGAAAAACTGTTTGCCAATC
TGAATAGTGCACCGATTCCGCTACCACTCTTGAGCCAGTACATGCCACGCCAATTTACTGCAGTTCGCGAAGGCACTCTG
TCTTTTGAAGCCACGGCATTGGTCAAACAACAAATCAAAAATACGCTTATTGGCTATGTCAATGCATGCCACCTTTTTAA
CGGGAACACATCGAAATGA

Upstream 100 bases:

>100_bases
CGACTACGGGATATGCGAATTGAAGTGATCATAGCTGAAAAAGAGAAATAACACCTTGACTCCATAGTGACATTATTAAT
GTTAATTGTGGAGTTAATGT

Downstream 100 bases:

>100_bases
CGCAATATTTAGGGTACAGCCGGGAAGAACTGACTCGCTTACATGCCAGTTGGACCGCACAGGAAATTGAACAACAGCCT
GCATGTTGGGGAAAAACACA

Product: tagatose 6-phosphate kinase 2

Products: ADP; D-tagatose 1,6-bisphosphate

Alternate protein names: NA

Number of amino acids: Translated: 432; Mature: 432

Protein sequence:

>432_residues
MHPLEKLVQRHKAGEQIGIYSVCSAHPLVIEAALEQALENDSELLIEATSNQVDQFGGYTGMTPVDFRDYVFAKADALHF
PLEKLILGGDHLGPNRWQHLPANEAMAHADDLIAAYVAAGFKKIHLDCSMSCADDPVPLSDEIVAERAARLAAIAEATEY
QHFNTHTAVYVIGTEVPIPGGATEELDEIEVTSPEAARKTIECHQKAFEKSGVAECWPRVIGLVVQPGVEFDHTGVIDFC
PEKAHELSKVMDEYDYQVFEAHSTDYQTDDAYRALVKGHFAILKVGPALTFALREALFSLCHIEEELFPAEQCSRLRQVM
EDVMLKSPEYWKRYYLGDTEQVRLARVYSFSDRMRYYWPMEAVQAAQEKLFANLNSAPIPLPLLSQYMPRQFTAVREGTL
SFEATALVKQQIKNTLIGYVNACHLFNGNTSK

Sequences:

>Translated_432_residues
MHPLEKLVQRHKAGEQIGIYSVCSAHPLVIEAALEQALENDSELLIEATSNQVDQFGGYTGMTPVDFRDYVFAKADALHF
PLEKLILGGDHLGPNRWQHLPANEAMAHADDLIAAYVAAGFKKIHLDCSMSCADDPVPLSDEIVAERAARLAAIAEATEY
QHFNTHTAVYVIGTEVPIPGGATEELDEIEVTSPEAARKTIECHQKAFEKSGVAECWPRVIGLVVQPGVEFDHTGVIDFC
PEKAHELSKVMDEYDYQVFEAHSTDYQTDDAYRALVKGHFAILKVGPALTFALREALFSLCHIEEELFPAEQCSRLRQVM
EDVMLKSPEYWKRYYLGDTEQVRLARVYSFSDRMRYYWPMEAVQAAQEKLFANLNSAPIPLPLLSQYMPRQFTAVREGTL
SFEATALVKQQIKNTLIGYVNACHLFNGNTSK
>Mature_432_residues
MHPLEKLVQRHKAGEQIGIYSVCSAHPLVIEAALEQALENDSELLIEATSNQVDQFGGYTGMTPVDFRDYVFAKADALHF
PLEKLILGGDHLGPNRWQHLPANEAMAHADDLIAAYVAAGFKKIHLDCSMSCADDPVPLSDEIVAERAARLAAIAEATEY
QHFNTHTAVYVIGTEVPIPGGATEELDEIEVTSPEAARKTIECHQKAFEKSGVAECWPRVIGLVVQPGVEFDHTGVIDFC
PEKAHELSKVMDEYDYQVFEAHSTDYQTDDAYRALVKGHFAILKVGPALTFALREALFSLCHIEEELFPAEQCSRLRQVM
EDVMLKSPEYWKRYYLGDTEQVRLARVYSFSDRMRYYWPMEAVQAAQEKLFANLNSAPIPLPLLSQYMPRQFTAVREGTL
SFEATALVKQQIKNTLIGYVNACHLFNGNTSK

Specific function: Component of the tagatose-1,6-bisphosphate aldolase kbaYZ that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of kbaY. When expressed alone, kbaZ does not show any aldol

COG id: COG4573

COG function: function code G; Predicted tagatose 6-phosphate kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gatZ/kbaZ family. KbaZ subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789520, Length=423, Percent_Identity=63.5933806146572, Blast_Score=553, Evalue=1e-159,
Organism=Escherichia coli, GI1788411, Length=422, Percent_Identity=52.60663507109, Blast_Score=428, Evalue=1e-121,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR012062 [H]

Pfam domain/function: PF08013 Tagatose_6_P_K [H]

EC number: 2.7.1.144

Molecular weight: Translated: 48387; Mature: 48387

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHPLEKLVQRHKAGEQIGIYSVCSAHPLVIEAALEQALENDSELLIEATSNQVDQFGGYT
CCHHHHHHHHHCCCCCCCHHHHHCCCHHHHHHHHHHHHCCCCEEEEEECHHHHHHHCCCC
GMTPVDFRDYVFAKADALHFPLEKLILGGDHLGPNRWQHLPANEAMAHADDLIAAYVAAG
CCCCCCHHHHHHHHHHHHHCCHHHHHCCCCCCCCCHHCCCCCHHHHHHHHHHHHHHHHHC
FKKIHLDCSMSCADDPVPLSDEIVAERAARLAAIAEATEYQHFNTHTAVYVIGTEVPIPG
CEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCC
GATEELDEIEVTSPEAARKTIECHQKAFEKSGVAECWPRVIGLVVQPGVEFDHTGVIDFC
CCCCCCCCEECCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCHHCC
PEKAHELSKVMDEYDYQVFEAHSTDYQTDDAYRALVKGHFAILKVGPALTFALREALFSL
HHHHHHHHHHHHHHCCCEEECCCCCCCCHHHHHHHHHCCEEEEEECHHHHHHHHHHHHHH
CHIEEELFPAEQCSRLRQVMEDVMLKSPEYWKRYYLGDTEQVRLARVYSFSDRMRYYWPM
HHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCHHHHHHHHHHHHCCCEEECCH
EAVQAAQEKLFANLNSAPIPLPLLSQYMPRQFTAVREGTLSFEATALVKQQIKNTLIGYV
HHHHHHHHHHHHCCCCCCCCHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
NACHLFNGNTSK
HHHEEECCCCCC
>Mature Secondary Structure
MHPLEKLVQRHKAGEQIGIYSVCSAHPLVIEAALEQALENDSELLIEATSNQVDQFGGYT
CCHHHHHHHHHCCCCCCCHHHHHCCCHHHHHHHHHHHHCCCCEEEEEECHHHHHHHCCCC
GMTPVDFRDYVFAKADALHFPLEKLILGGDHLGPNRWQHLPANEAMAHADDLIAAYVAAG
CCCCCCHHHHHHHHHHHHHCCHHHHHCCCCCCCCCHHCCCCCHHHHHHHHHHHHHHHHHC
FKKIHLDCSMSCADDPVPLSDEIVAERAARLAAIAEATEYQHFNTHTAVYVIGTEVPIPG
CEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCC
GATEELDEIEVTSPEAARKTIECHQKAFEKSGVAECWPRVIGLVVQPGVEFDHTGVIDFC
CCCCCCCCEECCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCHHCC
PEKAHELSKVMDEYDYQVFEAHSTDYQTDDAYRALVKGHFAILKVGPALTFALREALFSL
HHHHHHHHHHHHHHCCCEEECCCCCCCCHHHHHHHHHCCEEEEEECHHHHHHHHHHHHHH
CHIEEELFPAEQCSRLRQVMEDVMLKSPEYWKRYYLGDTEQVRLARVYSFSDRMRYYWPM
HHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCHHHHHHHHHHHHCCCEEECCH
EAVQAAQEKLFANLNSAPIPLPLLSQYMPRQFTAVREGTLSFEATALVKQQIKNTLIGYV
HHHHHHHHHHHHCCCCCCCCHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
NACHLFNGNTSK
HHHEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; D-tagatose 6-phosphate

Specific reaction: ATP + D-tagatose 6-phosphate = ADP + D-tagatose 1,6-bisphosphate

General reaction: Phospho group transfer [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA