Click here to switch to the map view.

The map label for this gene is lplT

Identifier: 22127056

GI number: 22127056

Start: 3497971

End: 3499191

Strand: Reverse

Name: lplT

Synonym: y3180

Alternate gene names: 22127056

Gene position: 3499191-3497971 (Counterclockwise)

Preceding gene: 161484766

Following gene: 22127054

Centisome position: 76.06

GC content: 52.83

Gene sequence:

>1221_bases
ATGAGTCAGGACGTATTAGCAGATAAGCCTTTGTTATCTCGGAGCATGGTCGCGGTACTCTGTGCTCAGTTTTTCTCCGC
TTTCGGGGATAATGCCCTGCTGTTTGCCACATTGGCATTGATTAAACAGCAACTTTATCCCGACTGGAGCCAACCTATTT
TACAGATGGCATTTGTCGCGACTTATATTGTTCTGGCACCGTTCGTCGGGCAGATTGCCGATGGTTTCGCCAAAGGCCGG
GTAATGATGGTGGCTAATGGTTTGAAATTGGCTGGCGCTCTGGTTATCTGTTTTGGTTTAAATCCGTTTCTGGGCTATAG
CCTGGTTGGGGTGGGAGCGGCAGCCTATTCACCAGCTAAATATGGCATTCTGGGGGAAATAACCTCTGGTGAGCAGTTGG
TGAAAGCAAACGGAATGATGGAAGCCTCGACGATCGCTGCGATCTTACTTGGCTCGGTTGCCGGGGGGATACTGGCAGAC
TGGCATTTAATGGCCGCATTAGGGGTTTGCGCCTTGGTCTATGCGATTGCGGTAATAGCCAATTTATTTATTCCACGTTT
GGCCGCAGCACGTTCAGGCGCTTCGTGGCGTCCACGGGCGATGACGGGCAGCTTCTTCACCGCTTGCCGTCTTCTCTGGC
AGGATAGCGAAACTCGCTTCTCATTGGCGGGTACCAGCCTGTTTTGGGGGGCCGGTGTGACGTTACGCTTCCTGTTAGTG
CTGTGGGTCCCTGTGGCGCTTGGCATTGCCGATAATGCGACACCAACCTTGTTAAATGCCATGGTGGCGATTGGGATTGT
GGTGGGCGCGGGTGCCGCCGCCCGTTTTGTGACGCTAAAAACAGTGAAGCGTTGTTTACCGGCTGGCGTGCTGATTGGCG
TGATGGTCACCATCTTCTCCCTGCAAAACAGTATGCCGATGGCTTATTTGCTGTTAATTATCATTGGGATTTTGGGAGGG
TTCTTTGTGGTCCCACTCAATGCGCTGCTACAGGAGCGTGGTAAACACAGCGTTGGGGCTGGGAATGCTATTGCCGTACA
GAATTTGGGCGAGAATACCGCGATGCTGTTTATGTTGGGGCTTTACTCGCTGGTGGTCAAATTAGGTGCCCCTGTTGTGG
CGGTAGGTGTCGGTTTTGGTGTGGTATTCGCGCTGGCTATTGCTCTGTTATGGGGCTGGCAGTGGCGGCAACAGCGCCAG
AAAACGCGTCAGCCTGAATGA

Upstream 100 bases:

>100_bases
CGCGCGATATCCGGGTCGTGAAAGCTCTCCCCTTATTAGGCAGCGGTAAACCTGACTTCGTCACGTTGGGCAAAATGGCA
CAAGATCCGGAGATGAGCGT

Downstream 100 bases:

>100_bases
TATGATTTGTCTGTCATCTGAAAGGATCTCAAGGAGATCCTTCAGACTGCTGACAAATATCGCCTTTTGAAATATCGATT
ATATTAACTTCAATGAGTTG

Product: lysophospholipid transporter LplT

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 406; Mature: 405

Protein sequence:

>406_residues
MSQDVLADKPLLSRSMVAVLCAQFFSAFGDNALLFATLALIKQQLYPDWSQPILQMAFVATYIVLAPFVGQIADGFAKGR
VMMVANGLKLAGALVICFGLNPFLGYSLVGVGAAAYSPAKYGILGEITSGEQLVKANGMMEASTIAAILLGSVAGGILAD
WHLMAALGVCALVYAIAVIANLFIPRLAAARSGASWRPRAMTGSFFTACRLLWQDSETRFSLAGTSLFWGAGVTLRFLLV
LWVPVALGIADNATPTLLNAMVAIGIVVGAGAAARFVTLKTVKRCLPAGVLIGVMVTIFSLQNSMPMAYLLLIIIGILGG
FFVVPLNALLQERGKHSVGAGNAIAVQNLGENTAMLFMLGLYSLVVKLGAPVVAVGVGFGVVFALAIALLWGWQWRQQRQ
KTRQPE

Sequences:

>Translated_406_residues
MSQDVLADKPLLSRSMVAVLCAQFFSAFGDNALLFATLALIKQQLYPDWSQPILQMAFVATYIVLAPFVGQIADGFAKGR
VMMVANGLKLAGALVICFGLNPFLGYSLVGVGAAAYSPAKYGILGEITSGEQLVKANGMMEASTIAAILLGSVAGGILAD
WHLMAALGVCALVYAIAVIANLFIPRLAAARSGASWRPRAMTGSFFTACRLLWQDSETRFSLAGTSLFWGAGVTLRFLLV
LWVPVALGIADNATPTLLNAMVAIGIVVGAGAAARFVTLKTVKRCLPAGVLIGVMVTIFSLQNSMPMAYLLLIIIGILGG
FFVVPLNALLQERGKHSVGAGNAIAVQNLGENTAMLFMLGLYSLVVKLGAPVVAVGVGFGVVFALAIALLWGWQWRQQRQ
KTRQPE
>Mature_405_residues
SQDVLADKPLLSRSMVAVLCAQFFSAFGDNALLFATLALIKQQLYPDWSQPILQMAFVATYIVLAPFVGQIADGFAKGRV
MMVANGLKLAGALVICFGLNPFLGYSLVGVGAAAYSPAKYGILGEITSGEQLVKANGMMEASTIAAILLGSVAGGILADW
HLMAALGVCALVYAIAVIANLFIPRLAAARSGASWRPRAMTGSFFTACRLLWQDSETRFSLAGTSLFWGAGVTLRFLLVL
WVPVALGIADNATPTLLNAMVAIGIVVGAGAAARFVTLKTVKRCLPAGVLIGVMVTIFSLQNSMPMAYLLLIIIGILGGF
FVVPLNALLQERGKHSVGAGNAIAVQNLGENTAMLFMLGLYSLVVKLGAPVVAVGVGFGVVFALAIALLWGWQWRQQRQK
TRQPE

Specific function: Catalyzes the facilitated diffusion of 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) into the cell

COG id: COG0477

COG function: function code GEPR; Permeases of the major facilitator superfamily

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. LplT (TC 2.A.1.42) family

Homologues:

Organism=Escherichia coli, GI1789200, Length=397, Percent_Identity=74.3073047858942, Blast_Score=555, Evalue=1e-159,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): LPLT_YERP3 (A7FFD2)

Other databases:

- EMBL:   CP000720
- RefSeq:   YP_001399960.1
- ProteinModelPortal:   A7FFD2
- STRING:   A7FFD2
- GeneID:   5388381
- GenomeReviews:   CP000720_GR
- KEGG:   ypi:YpsIP31758_0976
- eggNOG:   COG0477
- HOGENOM:   HBG364376
- OMA:   QFADSFA
- ProtClustDB:   PRK11195
- BioCyc:   YPSE349747:YPSIP31758_0976-MONOMER
- HAMAP:   MF_01585
- InterPro:   IPR011701
- InterPro:   IPR016196

Pfam domain/function: PF07690 MFS_1; SSF103473 MFS_gen_substrate_transporter

EC number: NA

Molecular weight: Translated: 42842; Mature: 42710

Theoretical pI: Translated: 10.01; Mature: 10.01

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1009e440)-; HASH(0x10487130)-; HASH(0x11b19100)-; HASH(0x1116399c)-; HASH(0xfc59b24)-; HASH(0x11d60aa0)-; HASH(0x115d8e84)-; HASH(0x112bb12c)-; HASH(0x11bedc64)-; HASH(0x11b615c4)-; HASH(0xdef8f44)-;

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQDVLADKPLLSRSMVAVLCAQFFSAFGDNALLFATLALIKQQLYPDWSQPILQMAFVA
CCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
TYIVLAPFVGQIADGFAKGRVMMVANGLKLAGALVICFGLNPFLGYSLVGVGAAAYSPAK
HHHHHHHHHHHHHHHHHCCEEEEEECCHHHHHHHHHHHCCCHHHHHHHHHHCHHHCCCCC
YGILGEITSGEQLVKANGMMEASTIAAILLGSVAGGILADWHLMAALGVCALVYAIAVIA
CCCEEECCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NLFIPRLAAARSGASWRPRAMTGSFFTACRLLWQDSETRFSLAGTSLFWGAGVTLRFLLV
HHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEECCCHHHHHCCHHHHHHHH
LWVPVALGIADNATPTLLNAMVAIGIVVGAGAAARFVTLKTVKRCLPAGVLIGVMVTIFS
HHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LQNSMPMAYLLLIIIGILGGFFVVPLNALLQERGKHSVGAGNAIAVQNLGENTAMLFMLG
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCHHHHHHHH
LYSLVVKLGAPVVAVGVGFGVVFALAIALLWGWQWRQQRQKTRQPE
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCH
>Mature Secondary Structure 
SQDVLADKPLLSRSMVAVLCAQFFSAFGDNALLFATLALIKQQLYPDWSQPILQMAFVA
CCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
TYIVLAPFVGQIADGFAKGRVMMVANGLKLAGALVICFGLNPFLGYSLVGVGAAAYSPAK
HHHHHHHHHHHHHHHHHCCEEEEEECCHHHHHHHHHHHCCCHHHHHHHHHHCHHHCCCCC
YGILGEITSGEQLVKANGMMEASTIAAILLGSVAGGILADWHLMAALGVCALVYAIAVIA
CCCEEECCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NLFIPRLAAARSGASWRPRAMTGSFFTACRLLWQDSETRFSLAGTSLFWGAGVTLRFLLV
HHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEECCCHHHHHCCHHHHHHHH
LWVPVALGIADNATPTLLNAMVAIGIVVGAGAAARFVTLKTVKRCLPAGVLIGVMVTIFS
HHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LQNSMPMAYLLLIIIGILGGFFVVPLNALLQERGKHSVGAGNAIAVQNLGENTAMLFMLG
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCHHHHHHHH
LYSLVVKLGAPVVAVGVGFGVVFALAIALLWGWQWRQQRQKTRQPE
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA