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The map label for this gene is ompH [H]

Identifier: 22127002

GI number: 22127002

Start: 3438379

End: 3438969

Strand: Reverse

Name: ompH [H]

Synonym: y3126

Alternate gene names: 22127002

Gene position: 3438969-3438379 (Counterclockwise)

Preceding gene: 22127003

Following gene: 22127001

Centisome position: 74.75

GC content: 45.01

Gene sequence:

>591_bases
TTGGTGAAATCTGACGCTTCATCAGGTGGGATACACTACCAAGTGCAATTCAAGGTGTCTCTGACACAAACGGGTAATGG
TAAGGAGTTTATAGTGAAAAAGTGGTTGTGTGCCGCAAGTCTAGGTTTAGCATTGGCTGCTTCAGCCAGCGTTCAAGCAG
CTGACAAAATTGCTATTGTTAATGTTTCCAGCATTTTCCAACAATTACCCGCGCGTGAAGCCGTGGCTAAGCAGCTGGAG
AATGAATTCAAAGGCCGTGCAACCGAACTGCAAGGAATGGAGCGCGATCTGCAGACTAAAATGCAGAAGCTACAACGTGA
TGGTTCTACCATGAAAGCCAGTGATCGTACCAAGCTGGAAAATGAAGTAATGAAACAGCGTGAAACTTTCTCTACTAAAG
CGCAGGCTTTTGAGCAAGATAACCGCCGTCGTCAGGCAGAAGAGCGTAACAAAATCCTGAGCCGTATTCAGGATGCTGTT
AAATCTGTTGCTACCAAAGGTGGCTATGACGTAGTCATTGATGCGAATGCAGTGGCATACGCTGATTCTTCTAAAGACAT
TACTGCTGACGTATTGAAACAGGTTAAATAA

Upstream 100 bases:

>100_bases
GAGCAATTCCAGTTTAACATTGGTAAAACTTGGTAATTGATGGGCAAAGCAGTTCTGAATTTTAAAGACAGCACTGGTAG
TGAAAGGATCTTAAGTCGCG

Downstream 100 bases:

>100_bases
AACATGCCTTCAATTCGACTGGCTGATTTAGCCCAGCAGTTGGATGCACAGGTGCACGGTGATGGCGATCTTGTCATCAC
CGGCATCGCTTCTATGCATT

Product: periplasmic chaperone

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 196; Mature: 196

Protein sequence:

>196_residues
MVKSDASSGGIHYQVQFKVSLTQTGNGKEFIVKKWLCAASLGLALAASASVQAADKIAIVNVSSIFQQLPAREAVAKQLE
NEFKGRATELQGMERDLQTKMQKLQRDGSTMKASDRTKLENEVMKQRETFSTKAQAFEQDNRRRQAEERNKILSRIQDAV
KSVATKGGYDVVIDANAVAYADSSKDITADVLKQVK

Sequences:

>Translated_196_residues
MVKSDASSGGIHYQVQFKVSLTQTGNGKEFIVKKWLCAASLGLALAASASVQAADKIAIVNVSSIFQQLPAREAVAKQLE
NEFKGRATELQGMERDLQTKMQKLQRDGSTMKASDRTKLENEVMKQRETFSTKAQAFEQDNRRRQAEERNKILSRIQDAV
KSVATKGGYDVVIDANAVAYADSSKDITADVLKQVK
>Mature_196_residues
MVKSDASSGGIHYQVQFKVSLTQTGNGKEFIVKKWLCAASLGLALAASASVQAADKIAIVNVSSIFQQLPAREAVAKQLE
NEFKGRATELQGMERDLQTKMQKLQRDGSTMKASDRTKLENEVMKQRETFSTKAQAFEQDNRRRQAEERNKILSRIQDAV
KSVATKGGYDVVIDANAVAYADSSKDITADVLKQVK

Specific function: Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm [H]

COG id: COG2825

COG function: function code M; Outer membrane protein

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the skp family [H]

Homologues:

Organism=Escherichia coli, GI1786375, Length=167, Percent_Identity=67.065868263473, Blast_Score=178, Evalue=2e-46,

Paralogues:

None

Copy number: 580 Molecules/Cell In: Growth-Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005632 [H]

Pfam domain/function: PF03938 OmpH [H]

EC number: NA

Molecular weight: Translated: 21587; Mature: 21587

Theoretical pI: Translated: 10.12; Mature: 10.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKSDASSGGIHYQVQFKVSLTQTGNGKEFIVKKWLCAASLGLALAASASVQAADKIAIV
CCCCCCCCCCEEEEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHEEEE
NVSSIFQQLPAREAVAKQLENEFKGRATELQGMERDLQTKMQKLQRDGSTMKASDRTKLE
EHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
NEVMKQRETFSTKAQAFEQDNRRRQAEERNKILSRIQDAVKSVATKGGYDVVIDANAVAY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCEEEE
ADSSKDITADVLKQVK
CCCCCCHHHHHHHHCC
>Mature Secondary Structure
MVKSDASSGGIHYQVQFKVSLTQTGNGKEFIVKKWLCAASLGLALAASASVQAADKIAIV
CCCCCCCCCCEEEEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHEEEE
NVSSIFQQLPAREAVAKQLENEFKGRATELQGMERDLQTKMQKLQRDGSTMKASDRTKLE
EHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
NEVMKQRETFSTKAQAFEQDNRRRQAEERNKILSRIQDAVKSVATKGGYDVVIDANAVAY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCEEEE
ADSSKDITADVLKQVK
CCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430 [H]