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The map label for this gene is pucI [H]

Identifier: 22126969

GI number: 22126969

Start: 3403208

End: 3404566

Strand: Direct

Name: pucI [H]

Synonym: y3093

Alternate gene names: 22126969

Gene position: 3403208-3404566 (Clockwise)

Preceding gene: 22126967

Following gene: 22126971

Centisome position: 73.97

GC content: 49.15

Gene sequence:

>1359_bases
ATGACGGATGTGCACAGCATGGGGGGTTATGTGGTCGCCGCCAGCTTCTTTGCTCTCGGGCTATCCAGTTGGCAAGTGCT
GTTATCGCTATTAGTCGGTATTTGCATTGTACAAATTTGCGCCAATCTGGTGGCCAAACCAAGCCAGATAGCCGGTGTGC
CCTATGCCGTTATCTGTCGACAATCTTTTGGGGTATTTGGAGCAAATATCCCAGCCGTTATCCGTGGGCTGATCGCCGTT
GCCTGGTATGGCATTCAAACCTATCTGGCGGGTAATGCTTTTATGCTCGTGATGCTGAAATTCTTCCCCAGCCTGATCCC
CCTGGCTCAGAGCCAATGGCTAGGGTTATCCACCCTCGGCTGGATCTGTTTCTCCATTATGTGGGTACTGCAGGCGATGG
TGTTCTGGCATGGGATGAATGCGATTAAGCGCTTTATTGATTTTGCCGGGCCGGCAGTCTATGTCGTGATGCTGTCATTG
GCGTTATGGATTGTCTATCAAACCGGCTGGAGTAACATTTCATTCACCCTCGCCAGTAAAATCTTAAGCCCATCAGAACA
GGTCTGGCAGATGCTGACGGCAACCGCGCTGGTCGTCTCTTATTTTGCCGGGCCATTACTGAACTTTGGTGATTTCTCCC
GCTATGGCAAAAGTATGCAGGAAATCCGCCGAGGCAACCGATGGGGGCTACCCTTTAACTTCCTCCTGTTCTCTCTCGTC
ACCGTGGTGATTGTCTCCGGCTCACAGTCGCTGTTCGGTGAAATGATTACCGACCCTATCGAGACCGTTACCCGCGTCGG
CAATGGCGTGGCTATCGCTCTAGGTCTACTGACCATGATTATCGCCACTATCGGGATTAATATCGTCGCAAACTTTGTTT
CACCCGCCTTTGATTTTTCTAACTGTTCACCACAAAGAATCAACTTTCGTACTGGTGGGATGATAGCTGCGGTAGGTTCA
GTTTTGCTTACCCCATGGAACCTGTTCCAATCACCAATCATTATCCACTACACCCTGGACGTGCTGGGTGCCTTTATGGG
GCCGCTATTTGGTATTTTAATCGCTGATTTTTATCTGATTAAACGCGGCCAATTATATGTAGATGATCTGTTTAATGCTT
CATCATCAGGACGTTATTGGTATCGCGGAGGTTTTAATCCGAAAGCGATTATGGCGTTACTGCCCGCAGTGGCCATTGGC
TTGATGATCATTTTCATCCCCAACCTACAGCAGATCTCCAGTTTCAGTTGGTTTATCGGGGCGTTTCTTGGCGGGAGTAT
TTATCGCTTTATTGCACGCAATGACCCATTGCCGAACAATGCGGCTCTGTTTATACGCCCTGAAATAGGCAAAGATTGA

Upstream 100 bases:

>100_bases
TAGCAGCATTAACCCCCACTACAGTCCCAAACTCACTAATGAAGATCTGGCCCCAACTCGTAAGCAGAACTGGGGCTGGT
ACAATATCTTTTCATTTTGG

Downstream 100 bases:

>100_bases
GTTAAGCAGAAACGACAAAGCCCTGAGTTATTACTTAACTCAGGGCTTCTAAATTTTGGCGGTGCGGACGGGACTCGAAC
CCGCGACCCCCGGCGTGACA

Product: permease

Products: NA

Alternate protein names: Allantoin transport protein [H]

Number of amino acids: Translated: 452; Mature: 451

Protein sequence:

>452_residues
MTDVHSMGGYVVAASFFALGLSSWQVLLSLLVGICIVQICANLVAKPSQIAGVPYAVICRQSFGVFGANIPAVIRGLIAV
AWYGIQTYLAGNAFMLVMLKFFPSLIPLAQSQWLGLSTLGWICFSIMWVLQAMVFWHGMNAIKRFIDFAGPAVYVVMLSL
ALWIVYQTGWSNISFTLASKILSPSEQVWQMLTATALVVSYFAGPLLNFGDFSRYGKSMQEIRRGNRWGLPFNFLLFSLV
TVVIVSGSQSLFGEMITDPIETVTRVGNGVAIALGLLTMIIATIGINIVANFVSPAFDFSNCSPQRINFRTGGMIAAVGS
VLLTPWNLFQSPIIIHYTLDVLGAFMGPLFGILIADFYLIKRGQLYVDDLFNASSSGRYWYRGGFNPKAIMALLPAVAIG
LMIIFIPNLQQISSFSWFIGAFLGGSIYRFIARNDPLPNNAALFIRPEIGKD

Sequences:

>Translated_452_residues
MTDVHSMGGYVVAASFFALGLSSWQVLLSLLVGICIVQICANLVAKPSQIAGVPYAVICRQSFGVFGANIPAVIRGLIAV
AWYGIQTYLAGNAFMLVMLKFFPSLIPLAQSQWLGLSTLGWICFSIMWVLQAMVFWHGMNAIKRFIDFAGPAVYVVMLSL
ALWIVYQTGWSNISFTLASKILSPSEQVWQMLTATALVVSYFAGPLLNFGDFSRYGKSMQEIRRGNRWGLPFNFLLFSLV
TVVIVSGSQSLFGEMITDPIETVTRVGNGVAIALGLLTMIIATIGINIVANFVSPAFDFSNCSPQRINFRTGGMIAAVGS
VLLTPWNLFQSPIIIHYTLDVLGAFMGPLFGILIADFYLIKRGQLYVDDLFNASSSGRYWYRGGFNPKAIMALLPAVAIG
LMIIFIPNLQQISSFSWFIGAFLGGSIYRFIARNDPLPNNAALFIRPEIGKD
>Mature_451_residues
TDVHSMGGYVVAASFFALGLSSWQVLLSLLVGICIVQICANLVAKPSQIAGVPYAVICRQSFGVFGANIPAVIRGLIAVA
WYGIQTYLAGNAFMLVMLKFFPSLIPLAQSQWLGLSTLGWICFSIMWVLQAMVFWHGMNAIKRFIDFAGPAVYVVMLSLA
LWIVYQTGWSNISFTLASKILSPSEQVWQMLTATALVVSYFAGPLLNFGDFSRYGKSMQEIRRGNRWGLPFNFLLFSLVT
VVIVSGSQSLFGEMITDPIETVTRVGNGVAIALGLLTMIIATIGINIVANFVSPAFDFSNCSPQRINFRTGGMIAAVGSV
LLTPWNLFQSPIIIHYTLDVLGAFMGPLFGILIADFYLIKRGQLYVDDLFNASSSGRYWYRGGFNPKAIMALLPAVAIGL
MIIFIPNLQQISSFSWFIGAFLGGSIYRFIARNDPLPNNAALFIRPEIGKD

Specific function: Transport of allantoin [H]

COG id: COG1953

COG function: function code FH; Cytosine/uracil/thiamine/allantoin permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine-cytosine permease family [H]

Homologues:

Organism=Escherichia coli, GI87081749, Length=436, Percent_Identity=28.4403669724771, Blast_Score=190, Evalue=1e-49,
Organism=Saccharomyces cerevisiae, GI6322219, Length=413, Percent_Identity=22.2760290556901, Blast_Score=113, Evalue=7e-26,
Organism=Saccharomyces cerevisiae, GI6319495, Length=410, Percent_Identity=21.219512195122, Blast_Score=108, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6319429, Length=399, Percent_Identity=20.5513784461153, Blast_Score=97, Evalue=6e-21,
Organism=Saccharomyces cerevisiae, GI6324766, Length=409, Percent_Identity=21.2713936430318, Blast_Score=87, Evalue=7e-18,
Organism=Saccharomyces cerevisiae, GI6323266, Length=409, Percent_Identity=22.2493887530562, Blast_Score=86, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6324645, Length=416, Percent_Identity=20.9134615384615, Blast_Score=83, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001248
- InterPro:   IPR012681 [H]

Pfam domain/function: PF02133 Transp_cyt_pur [H]

EC number: NA

Molecular weight: Translated: 49516; Mature: 49385

Theoretical pI: Translated: 9.41; Mature: 9.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHCCCCCCCCCEEEEECCCCCC
>Mature Secondary Structure 
TDVHSMGGYVVAASFFALGLSSWQVLLSLLVGICIVQICANLVAKPSQIAGVPYAVICR
CCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCHHHHHH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HHHHHHHHHHHHCCCCCCCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377; 11344136 [H]