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The map label for this gene is intA [H]

Identifier: 22126957

GI number: 22126957

Start: 3390110

End: 3391342

Strand: Direct

Name: intA [H]

Synonym: y3081

Alternate gene names: 22126957

Gene position: 3390110-3391342 (Clockwise)

Preceding gene: 22126956

Following gene: 22126958

Centisome position: 73.69

GC content: 45.74

Gene sequence:

>1233_bases
ATGGACGTATACCAATTAAGGGAAGAACCATACATGGCAAGGACAACACGCCCCCTCACCCACACCGAAGTACAAAAAGC
AAAAGCCACCGACAAAGACCTAACCCTCCATGATGGTGATGGTTTATTTTTGCTAGTCAAAACTACCGGCAAGAAAATTT
GGCGTTTCCGCTATCAGCTTCCCAACAGTAGCAAGCGCACTATGATCAGCCTCGGTGCTTACCCAGCACTATCCCTCGCA
GATGCCAGAGAGATACGCGCAGAAAAACTAGCGATGTTAGTCAGAGGGACAGACCCTCAAACGAGGGCTGGTGAAGAGGC
TGAAAAGCTCCAGATAGCGGAGGAAAGCATTTTTGTGAATGTCGCCCGCAAATGGTTCGAGTTGAAAGAAAGCCATGTTA
GCGCAGCCCATGCGAAAGATATTTGGCGTTCTATTGAAAAAGACATCTTACCCAGCATCGAAAATATTCCCATCCAAGAA
CTTAAAGCACGAACTCTGATTCAAGTATTGGAGCCAATCAAAGCACGTGGAGCATTAGAGACGGTCAGGCGATTGGTACA
ACGTATAAACGAGATAATGATCTATGCGGTCAATGTAGGTTTGATTGATGCTAACCCAGCTTCAGGTATCGGTAATGCTT
TTGAACGCCCCAAGAAGCAGCATATGCCCACCATCAGACCTGAAGAACTACCTAAACTCATGCGTACCATTGCCATGAGC
AATCTCTCACTGCCAACCCGCTGCTTACTTGAATGGCAATTACTAACTCTGATACGCCCCGCTGAAGCATCAGCAACAGC
TTGGATAGAGATCGATTTAGAGAATAAGCAGTGGTGTATACCGGCAGAACGAATGAAAGCAAAGCGCGACCATATAGTCC
CGTTGTCGGAACAAGCCTTAGAGTTGCTGGAAATAATGCGTCCAATTAGTGGTAATCGTCAGCACGTATTCCCAAGTCGC
AATGACCCACGTAATCACATGAATAGCCAAACAGCAAATGCAGCCTTGAAACGTATTGGTTATGGAGGGAAGCTCGTTGC
TCACGGTTTACGTTCTATCGCCAGTACAGCCATGAATGAGGCTGGGTTTAATGCTGATGTGATTGAGGCTGCGCTAGCGC
ATAGTGATAAGAATGAAGTCAGGAAAGCTTATAATCGTTCTACCTATCTCATACAACGCCAAGAGTTAATGAATTGGTGG
GGATTAGAGATATACACTAAAAGAAGTATTTAA

Upstream 100 bases:

>100_bases
TGCCGGAGGATATTTATTTGTGTCTGTAGTAGTCCAAGAGGATCCGGCTGAATCCAGTGTCTATTGGTATACAAATTGGT
ATACGCTAAGATAGGTATCA

Downstream 100 bases:

>100_bases
CGTAAGTGAAAGTCATAGACGTTTCCCTTAGCACGTATTATCTTTTAGTATCACTCATAAAATGGACAGGCCACTAAAAT
GGATAGTGAAGACACATCTG

Product: prophage CP4-57 integrase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 410; Mature: 410

Protein sequence:

>410_residues
MDVYQLREEPYMARTTRPLTHTEVQKAKATDKDLTLHDGDGLFLLVKTTGKKIWRFRYQLPNSSKRTMISLGAYPALSLA
DAREIRAEKLAMLVRGTDPQTRAGEEAEKLQIAEESIFVNVARKWFELKESHVSAAHAKDIWRSIEKDILPSIENIPIQE
LKARTLIQVLEPIKARGALETVRRLVQRINEIMIYAVNVGLIDANPASGIGNAFERPKKQHMPTIRPEELPKLMRTIAMS
NLSLPTRCLLEWQLLTLIRPAEASATAWIEIDLENKQWCIPAERMKAKRDHIVPLSEQALELLEIMRPISGNRQHVFPSR
NDPRNHMNSQTANAALKRIGYGGKLVAHGLRSIASTAMNEAGFNADVIEAALAHSDKNEVRKAYNRSTYLIQRQELMNWW
GLEIYTKRSI

Sequences:

>Translated_410_residues
MDVYQLREEPYMARTTRPLTHTEVQKAKATDKDLTLHDGDGLFLLVKTTGKKIWRFRYQLPNSSKRTMISLGAYPALSLA
DAREIRAEKLAMLVRGTDPQTRAGEEAEKLQIAEESIFVNVARKWFELKESHVSAAHAKDIWRSIEKDILPSIENIPIQE
LKARTLIQVLEPIKARGALETVRRLVQRINEIMIYAVNVGLIDANPASGIGNAFERPKKQHMPTIRPEELPKLMRTIAMS
NLSLPTRCLLEWQLLTLIRPAEASATAWIEIDLENKQWCIPAERMKAKRDHIVPLSEQALELLEIMRPISGNRQHVFPSR
NDPRNHMNSQTANAALKRIGYGGKLVAHGLRSIASTAMNEAGFNADVIEAALAHSDKNEVRKAYNRSTYLIQRQELMNWW
GLEIYTKRSI
>Mature_410_residues
MDVYQLREEPYMARTTRPLTHTEVQKAKATDKDLTLHDGDGLFLLVKTTGKKIWRFRYQLPNSSKRTMISLGAYPALSLA
DAREIRAEKLAMLVRGTDPQTRAGEEAEKLQIAEESIFVNVARKWFELKESHVSAAHAKDIWRSIEKDILPSIENIPIQE
LKARTLIQVLEPIKARGALETVRRLVQRINEIMIYAVNVGLIDANPASGIGNAFERPKKQHMPTIRPEELPKLMRTIAMS
NLSLPTRCLLEWQLLTLIRPAEASATAWIEIDLENKQWCIPAERMKAKRDHIVPLSEQALELLEIMRPISGNRQHVFPSR
NDPRNHMNSQTANAALKRIGYGGKLVAHGLRSIASTAMNEAGFNADVIEAALAHSDKNEVRKAYNRSTYLIQRQELMNWW
GLEIYTKRSI

Specific function: Integrase is necessary for integration of the phage into the host genome by site-specific recombination. In conjunction with excisionase, integrase is also necessary for excision of the prophage from the host genome [H]

COG id: COG0582

COG function: function code L; Integrase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family [H]

Homologues:

Organism=Escherichia coli, GI1788974, Length=390, Percent_Identity=57.6923076923077, Blast_Score=481, Evalue=1e-137,
Organism=Escherichia coli, GI1788690, Length=386, Percent_Identity=31.6062176165803, Blast_Score=211, Evalue=8e-56,
Organism=Escherichia coli, GI145693166, Length=392, Percent_Identity=34.4387755102041, Blast_Score=198, Evalue=5e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR023109 [H]

Pfam domain/function: PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 46662; Mature: 46662

Theoretical pI: Translated: 10.04; Mature: 10.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDVYQLREEPYMARTTRPLTHTEVQKAKATDKDLTLHDGDGLFLLVKTTGKKIWRFRYQL
CCCHHHCCCCCHHHCCCCCHHHHHHHHHCCCCCCEEECCCCEEEEEECCCCEEEEEEEEC
PNSSKRTMISLGAYPALSLADAREIRAEKLAMLVRGTDPQTRAGEEAEKLQIAEESIFVN
CCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHH
VARKWFELKESHVSAAHAKDIWRSIEKDILPSIENIPIQELKARTLIQVLEPIKARGALE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHH
TVRRLVQRINEIMIYAVNVGLIDANPASGIGNAFERPKKQHMPTIRPEELPKLMRTIAMS
HHHHHHHHHHHHEEEEEEEEEEECCCCCCCCHHHHCCHHHCCCCCCHHHHHHHHHHHHHH
NLSLPTRCLLEWQLLTLIRPAEASATAWIEIDLENKQWCIPAERMKAKRDHIVPLSEQAL
CCCCCHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCEECCHHHHHHHHCCCCCCHHHHH
ELLEIMRPISGNRQHVFPSRNDPRNHMNSQTANAALKRIGYGGKLVAHGLRSIASTAMNE
HHHHHHCCCCCCCCEECCCCCCCHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
AGFNADVIEAALAHSDKNEVRKAYNRSTYLIQRQELMNWWGLEIYTKRSI
CCCCHHHHHHHHHCCCHHHHHHHHCCCHHEEEHHHHHHHHCCEEEEECCC
>Mature Secondary Structure
MDVYQLREEPYMARTTRPLTHTEVQKAKATDKDLTLHDGDGLFLLVKTTGKKIWRFRYQL
CCCHHHCCCCCHHHCCCCCHHHHHHHHHCCCCCCEEECCCCEEEEEECCCCEEEEEEEEC
PNSSKRTMISLGAYPALSLADAREIRAEKLAMLVRGTDPQTRAGEEAEKLQIAEESIFVN
CCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHH
VARKWFELKESHVSAAHAKDIWRSIEKDILPSIENIPIQELKARTLIQVLEPIKARGALE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHH
TVRRLVQRINEIMIYAVNVGLIDANPASGIGNAFERPKKQHMPTIRPEELPKLMRTIAMS
HHHHHHHHHHHHEEEEEEEEEEECCCCCCCCHHHHCCHHHCCCCCCHHHHHHHHHHHHHH
NLSLPTRCLLEWQLLTLIRPAEASATAWIEIDLENKQWCIPAERMKAKRDHIVPLSEQAL
CCCCCHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCEECCHHHHHHHHCCCCCCHHHHH
ELLEIMRPISGNRQHVFPSRNDPRNHMNSQTANAALKRIGYGGKLVAHGLRSIASTAMNE
HHHHHHCCCCCCCCEECCCCCCCHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
AGFNADVIEAALAHSDKNEVRKAYNRSTYLIQRQELMNWWGLEIYTKRSI
CCCCHHHHHHHHHCCCHHHHHHHHCCCHHEEEHHHHHHHHCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7511583; 9278503; 9205837; 7524073 [H]