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The map label for this gene is ompC [H]

Identifier: 22126843

GI number: 22126843

Start: 3264464

End: 3265588

Strand: Reverse

Name: ompC [H]

Synonym: y2966

Alternate gene names: 22126843

Gene position: 3265588-3264464 (Counterclockwise)

Preceding gene: 22126848

Following gene: 22126842

Centisome position: 70.98

GC content: 44.18

Gene sequence:

>1125_bases
ATGATAACAATGAAACTTCGAGTTCTTTCATTCATTATTCCGGCCTTATTGGTTGCAGGCAGTGCAAGTGCTGCGGAAAT
ATACAATAAAGACGGTAATAAACTGGATTTATACGGTAAAATTGACGGGTTACATTATTTTTCCGATAACAAGAACCTTG
ATGGTGACCAATCTTACATGCGTTTTGGCCTGAAAGGCGAAACACAAATCACTGACCAACTGACTGGTTATGGTCAGTGG
GAATATCAGGTCAATCTGAATAAAGCAGAGAATGAGGACGGGAACCACGACAGTTTCACCCGTGTAGGTTTTGCGGGTCT
GAAATTTGCTGACTACGGTTCATTAGATTATGGCCGTAACTACGGTGTCCTGTACGATGTCACTTCATGGACTGACGTTC
TGCCAGAATTTGGTGGTGATACTTACGGTGCTGATAACTTCCTGTCACAACGCGGTAACGGGATGCTGACTTACCGTAAC
ACCAATTTCTTCGGCTTGGTTGATGGCCTGAACTTTGCTCTGCAATATCAGGGTAAAAATGGCAGCAGTAGTGAAACCAA
CAATGGTCGCGGTGTAGCAGATCAAAACGGTGATGGCTACGGGATGTCCTTGTCTTATGACCTGGGTTGGGGGGTGAGTG
CATCAGCAGCGATGGCGAGTTCTCTGCGTACCACTGCGCAAAATGACCTGCAGTATGGCCAGGGTAAGCGTGCCAATGCC
TACACCGGTGGTCTGAAATATGATGCGAACAACGTTTATCTGGCCGCTAACTATACTCAGACTTACAACCTGACTCGTTT
CGGTGATTTCAGCAATAGATCAAGTGATGCCGCTTTCGGTTTTGCAGATAAAGCACACAACATTGAAGTCGTTGCTCAAT
ACCAGTTCGATTTTGGTCTACGTCCATCAGTGGCTTACCTGCAATCCAAAGGTAAAGACATTGGGATCTATGGCGATCAA
GATCTGCTGAAATATGTTGATATTGGTGCGACTTACTTCTTCAACAAAAACATGTCCACCTATGTGGATTACAAAATCAA
CTTGTTGGATAAAAACGATTTCACCAAAAATGCCCGCATAAATACTGATGATATTGTCGCAGTAGGTATGGTCTATCAGT
TCTAA

Upstream 100 bases:

>100_bases
TCTATATGGATTAATGGTTGTATTATTATCACAATATAGTTACCTCGTAGGCAGTATATTCTCGAAAGAGTAGTGGTATA
GATATATCTAATAATAGAGG

Downstream 100 bases:

>100_bases
TTCTGATTATAGGTGTGAGTCCTGAGAGAAACGCGGTCATTCGGCCGCGTTTCTTATTGTGCCCAGAAAACCCCCAGCTA
GGCTGGGGGTTCAGTAAAGC

Product: outer membrane porin protein C

Products: NA

Alternate protein names: Porin ompC [H]

Number of amino acids: Translated: 374; Mature: 374

Protein sequence:

>374_residues
MITMKLRVLSFIIPALLVAGSASAAEIYNKDGNKLDLYGKIDGLHYFSDNKNLDGDQSYMRFGLKGETQITDQLTGYGQW
EYQVNLNKAENEDGNHDSFTRVGFAGLKFADYGSLDYGRNYGVLYDVTSWTDVLPEFGGDTYGADNFLSQRGNGMLTYRN
TNFFGLVDGLNFALQYQGKNGSSSETNNGRGVADQNGDGYGMSLSYDLGWGVSASAAMASSLRTTAQNDLQYGQGKRANA
YTGGLKYDANNVYLAANYTQTYNLTRFGDFSNRSSDAAFGFADKAHNIEVVAQYQFDFGLRPSVAYLQSKGKDIGIYGDQ
DLLKYVDIGATYFFNKNMSTYVDYKINLLDKNDFTKNARINTDDIVAVGMVYQF

Sequences:

>Translated_374_residues
MITMKLRVLSFIIPALLVAGSASAAEIYNKDGNKLDLYGKIDGLHYFSDNKNLDGDQSYMRFGLKGETQITDQLTGYGQW
EYQVNLNKAENEDGNHDSFTRVGFAGLKFADYGSLDYGRNYGVLYDVTSWTDVLPEFGGDTYGADNFLSQRGNGMLTYRN
TNFFGLVDGLNFALQYQGKNGSSSETNNGRGVADQNGDGYGMSLSYDLGWGVSASAAMASSLRTTAQNDLQYGQGKRANA
YTGGLKYDANNVYLAANYTQTYNLTRFGDFSNRSSDAAFGFADKAHNIEVVAQYQFDFGLRPSVAYLQSKGKDIGIYGDQ
DLLKYVDIGATYFFNKNMSTYVDYKINLLDKNDFTKNARINTDDIVAVGMVYQF
>Mature_374_residues
MITMKLRVLSFIIPALLVAGSASAAEIYNKDGNKLDLYGKIDGLHYFSDNKNLDGDQSYMRFGLKGETQITDQLTGYGQW
EYQVNLNKAENEDGNHDSFTRVGFAGLKFADYGSLDYGRNYGVLYDVTSWTDVLPEFGGDTYGADNFLSQRGNGMLTYRN
TNFFGLVDGLNFALQYQGKNGSSSETNNGRGVADQNGDGYGMSLSYDLGWGVSASAAMASSLRTTAQNDLQYGQGKRANA
YTGGLKYDANNVYLAANYTQTYNLTRFGDFSNRSSDAAFGFADKAHNIEVVAQYQFDFGLRPSVAYLQSKGKDIGIYGDQ
DLLKYVDIGATYFFNKNMSTYVDYKINLLDKNDFTKNARINTDDIVAVGMVYQF

Specific function: Forms passive diffusion pores which allow small molecular weight hydrophilic materials across the outer membrane [H]

COG id: COG3203

COG function: function code M; Outer membrane protein (porin)

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Gram-negative porin family [H]

Homologues:

Organism=Escherichia coli, GI1788544, Length=381, Percent_Identity=70.3412073490814, Blast_Score=518, Evalue=1e-148,
Organism=Escherichia coli, GI1787641, Length=386, Percent_Identity=62.1761658031088, Blast_Score=431, Evalue=1e-122,
Organism=Escherichia coli, GI1786436, Length=373, Percent_Identity=56.0321715817694, Blast_Score=399, Evalue=1e-112,
Organism=Escherichia coli, GI1787160, Length=378, Percent_Identity=55.2910052910053, Blast_Score=373, Evalue=1e-104,

Paralogues:

None

Copy number: 6020 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 19068 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001897
- InterPro:   IPR013793
- InterPro:   IPR001702 [H]

Pfam domain/function: PF00267 Porin_1 [H]

EC number: NA

Molecular weight: Translated: 41409; Mature: 41409

Theoretical pI: Translated: 4.64; Mature: 4.64

Prosite motif: PS00576 GRAM_NEG_PORIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITMKLRVLSFIIPALLVAGSASAAEIYNKDGNKLDLYGKIDGLHYFSDNKNLDGDQSYM
CEEEHHHHHHHHHHHHHHCCCCCHHHHHCCCCCEEEEEEEECCEEEECCCCCCCCCHHHH
RFGLKGETQITDQLTGYGQWEYQVNLNKAENEDGNHDSFTRVGFAGLKFADYGSLDYGRN
EECCCCCCEEHHHHCCCEEEEEEEECCCCCCCCCCCCCEEEECCCCEEEECCCCCCCCCC
YGVLYDVTSWTDVLPEFGGDTYGADNFLSQRGNGMLTYRNTNFFGLVDGLNFALQYQGKN
CCEEEECCCHHHHHHHHCCCCCCCHHHHHHCCCEEEEEECCCEEEEECCCEEEEEECCCC
GSSSETNNGRGVADQNGDGYGMSLSYDLGWGVSASAAMASSLRTTAQNDLQYGQGKRANA
CCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCE
YTGGLKYDANNVYLAANYTQTYNLTRFGDFSNRSSDAAFGFADKAHNIEVVAQYQFDFGL
EECCEEECCCCEEEEEECEEEEEEEECCCCCCCCCCCEEECCCCCCCEEEEEEEEECCCC
RPSVAYLQSKGKDIGIYGDQDLLKYVDIGATYFFNKNMSTYVDYKINLLDKNDFTKNARI
CCCHHHHHCCCCEEEEECCHHHHHHHHCCEEEEECCCCCEEEEEEEEEEECCCCCCCCCC
NTDDIVAVGMVYQF
CCCCEEEEEEEECC
>Mature Secondary Structure
MITMKLRVLSFIIPALLVAGSASAAEIYNKDGNKLDLYGKIDGLHYFSDNKNLDGDQSYM
CEEEHHHHHHHHHHHHHHCCCCCHHHHHCCCCCEEEEEEEECCEEEECCCCCCCCCHHHH
RFGLKGETQITDQLTGYGQWEYQVNLNKAENEDGNHDSFTRVGFAGLKFADYGSLDYGRN
EECCCCCCEEHHHHCCCEEEEEEEECCCCCCCCCCCCCEEEECCCCEEEECCCCCCCCCC
YGVLYDVTSWTDVLPEFGGDTYGADNFLSQRGNGMLTYRNTNFFGLVDGLNFALQYQGKN
CCEEEECCCHHHHHHHHCCCCCCCHHHHHHCCCEEEEEECCCEEEEECCCEEEEEECCCC
GSSSETNNGRGVADQNGDGYGMSLSYDLGWGVSASAAMASSLRTTAQNDLQYGQGKRANA
CCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCE
YTGGLKYDANNVYLAANYTQTYNLTRFGDFSNRSSDAAFGFADKAHNIEVVAQYQFDFGL
EECCEEECCCCEEEEEECEEEEEEEECCCCCCCCCCCEEECCCCCCCEEEEEEEEECCCC
RPSVAYLQSKGKDIGIYGDQDLLKYVDIGATYFFNKNMSTYVDYKINLLDKNDFTKNARI
CCCHHHHHCCCCEEEEECCHHHHHHHHCCEEEEECCCCCEEEEEEEEEEECCCCCCCCCC
NTDDIVAVGMVYQF
CCCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2684785; 3412902; 11677608; 12644504; 10405180 [H]