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The map label for this gene is tcp [H]

Identifier: 22126835

GI number: 22126835

Start: 3256754

End: 3258568

Strand: Direct

Name: tcp [H]

Synonym: y2958

Alternate gene names: 22126835

Gene position: 3256754-3258568 (Clockwise)

Preceding gene: 22126834

Following gene: 22126837

Centisome position: 70.79

GC content: 50.14

Gene sequence:

>1815_bases
ATGTTTTCCTTTCTATTAGGACACTCTATGCTTGATTCCATTCGCTCACGTATTTTGGCAGCCTGTATTATCATCGTTGC
GGGTTCGCTCGCCATTAACACCTTCCTCAACTATTCCGTTGCCAATAAATATAATAACAGCGCCATCGATAATACCCTGA
CGGCACTCACTGTTAGCCACAGTGTCAGCATTGCTGAATGGGTGGCATCCAAAACACAAATGATTATGTCGCTCAAAGAC
AGCGCATTGACCGCCGATCCACTCGCAGCACTAAAGCAAGTGGCTGCAGCAGGCGGCTTTATTAATGTCTATATTGGCTA
TGCCGATAAAACGGCTATTTTTTCCAACCCGGATGGCATTCCTGCCGATTATGACCCCACCGGACGCCCGTGGTATCTAC
AAGCCGTGAATGCAGGCAAGCCAGTGGTGACACCTCCGTATATCGATGCGGGGACCCAGCAGTTAGTCGTCACATTTGCA
TGGTCCATCGTTCAGGATGGGGTTCTTAAAGGCGTGATCGCTGCCGATGTCACTATGGGAAGTGTCATTGCCAATGTAAA
TGCTATACACCCAACCGATAATAGCTTCGGAATGCTAATCGGGGCTGATGGCACAATCATCGCCCATCCTGAGACGCTGC
TGACCCTTAAGCCATTGGCCGATATCGCGCCGAACCTGAATTTACAAACCCTGCTGACGGCAACGGTACCTGTTTCAACG
GATATTAGCGGCAGCAGCAAATTATTGCTCGCCCAGGCGGTCCCTGGAACCCAGTGGTTTACCGTCGTTGCGCTGGATAA
ATCTCAAGCAACTGCGGGAATACATTCATTATTAACGACATCATTAGTAACATTGGTGATAATTATCTTCATCTCGGCGG
GGGTGATAGCGCTGATCACCCAACGCGCCCTGACACCATTAACACATATTCAGCAAGCGATGGATGCTATCAGTTCCGGC
TCGGCAGACCTCACTCAACGCCTCCCGATCGAAGGCCGTGATGAAGTAGCACAGATTGCCCGTTCATTTAATCAGTTTGC
GGATAAGCTCAGTCTGGTTATGGCTCAAATCCGTGGTACCAGCGAGTCTGTCCGGGTAGCAGCGAATGAAATCGCAGCAG
GCAACCAAGACTTATCGGGTAGAACAGAATCAGCCGCCGCCAGTTTGCAGCAAACCTCAGCAGCGCTGGAACAAATTTCG
GCAACCGTCGCTCAATCAGCCAGTGCCGCACGGCAAGCTAACAACGCGGTATTTTCTGCCTCTGAGGATGCTTCTCGCGG
TGGCGACGTTATCACTAAAGTCATCACAACGATGGAGTCAATTGAAAAGGCCTCGGGAAAAATTGGCGATATCACTAGCG
TCATTGATGGCATTGCTTTCCAAACAAATATTCTGGCACTGAATGCTGCCGTCGAGGCCGCTCGAGCAGGAGAACAAGGA
CGAGGTTTTGCCGTGGTTGCAGGCGAAGTCCGTATACTGGCACAACGCAGTGCACAAGCGGCTAAAGAGATAAAAGCCCT
GATCGAATCGACGGTCAGCAGTGTGGCATCCGGCTCCAGCCAAGTGCGCCAAGCCAGTAATGCCATGACCGATATTGTCA
GTAGTGTCTCTGATGTCACGACCATTATGTCGGAGATCACCAATGCCGCTGATGAACAAATGCGTGGTATTCACGAAATA
AATAGTGCAGTAGCGCAATTAGATACAATGGTGCAACAGAATGCCGCACTGGTGCAGGAGTCAACGGCCGCTTCAGCCGC
CTTACAAGCTCAGGCCGCTGATTTAACTGATACCGTTAATCAATTTAAGATCTAA

Upstream 100 bases:

>100_bases
GCACCATGTACACATGAGCAATAATTAACAGTAGTCATTAATTACAGTTTATTACTGTGACTCAGCTCAAGTTTTTTCCT
GCCAAGCCGTTACTTGAATC

Downstream 100 bases:

>100_bases
CGCGCTGCTGCTATCAACCAGAACCGCCGTCATTCAGTTCCAGCAGGTTATTCATCCACCCGCTGGAACGTGACTATTCC
AGTATGATCCGTGCACCTAT

Product: methyl-accepting chemotaxis transmembrane protein

Products: NA

Alternate protein names: Citrate chemoreceptor protein [H]

Number of amino acids: Translated: 604; Mature: 604

Protein sequence:

>604_residues
MFSFLLGHSMLDSIRSRILAACIIIVAGSLAINTFLNYSVANKYNNSAIDNTLTALTVSHSVSIAEWVASKTQMIMSLKD
SALTADPLAALKQVAAAGGFINVYIGYADKTAIFSNPDGIPADYDPTGRPWYLQAVNAGKPVVTPPYIDAGTQQLVVTFA
WSIVQDGVLKGVIAADVTMGSVIANVNAIHPTDNSFGMLIGADGTIIAHPETLLTLKPLADIAPNLNLQTLLTATVPVST
DISGSSKLLLAQAVPGTQWFTVVALDKSQATAGIHSLLTTSLVTLVIIIFISAGVIALITQRALTPLTHIQQAMDAISSG
SADLTQRLPIEGRDEVAQIARSFNQFADKLSLVMAQIRGTSESVRVAANEIAAGNQDLSGRTESAAASLQQTSAALEQIS
ATVAQSASAARQANNAVFSASEDASRGGDVITKVITTMESIEKASGKIGDITSVIDGIAFQTNILALNAAVEAARAGEQG
RGFAVVAGEVRILAQRSAQAAKEIKALIESTVSSVASGSSQVRQASNAMTDIVSSVSDVTTIMSEITNAADEQMRGIHEI
NSAVAQLDTMVQQNAALVQESTAASAALQAQAADLTDTVNQFKI

Sequences:

>Translated_604_residues
MFSFLLGHSMLDSIRSRILAACIIIVAGSLAINTFLNYSVANKYNNSAIDNTLTALTVSHSVSIAEWVASKTQMIMSLKD
SALTADPLAALKQVAAAGGFINVYIGYADKTAIFSNPDGIPADYDPTGRPWYLQAVNAGKPVVTPPYIDAGTQQLVVTFA
WSIVQDGVLKGVIAADVTMGSVIANVNAIHPTDNSFGMLIGADGTIIAHPETLLTLKPLADIAPNLNLQTLLTATVPVST
DISGSSKLLLAQAVPGTQWFTVVALDKSQATAGIHSLLTTSLVTLVIIIFISAGVIALITQRALTPLTHIQQAMDAISSG
SADLTQRLPIEGRDEVAQIARSFNQFADKLSLVMAQIRGTSESVRVAANEIAAGNQDLSGRTESAAASLQQTSAALEQIS
ATVAQSASAARQANNAVFSASEDASRGGDVITKVITTMESIEKASGKIGDITSVIDGIAFQTNILALNAAVEAARAGEQG
RGFAVVAGEVRILAQRSAQAAKEIKALIESTVSSVASGSSQVRQASNAMTDIVSSVSDVTTIMSEITNAADEQMRGIHEI
NSAVAQLDTMVQQNAALVQESTAASAALQAQAADLTDTVNQFKI
>Mature_604_residues
MFSFLLGHSMLDSIRSRILAACIIIVAGSLAINTFLNYSVANKYNNSAIDNTLTALTVSHSVSIAEWVASKTQMIMSLKD
SALTADPLAALKQVAAAGGFINVYIGYADKTAIFSNPDGIPADYDPTGRPWYLQAVNAGKPVVTPPYIDAGTQQLVVTFA
WSIVQDGVLKGVIAADVTMGSVIANVNAIHPTDNSFGMLIGADGTIIAHPETLLTLKPLADIAPNLNLQTLLTATVPVST
DISGSSKLLLAQAVPGTQWFTVVALDKSQATAGIHSLLTTSLVTLVIIIFISAGVIALITQRALTPLTHIQQAMDAISSG
SADLTQRLPIEGRDEVAQIARSFNQFADKLSLVMAQIRGTSESVRVAANEIAAGNQDLSGRTESAAASLQQTSAALEQIS
ATVAQSASAARQANNAVFSASEDASRGGDVITKVITTMESIEKASGKIGDITSVIDGIAFQTNILALNAAVEAARAGEQG
RGFAVVAGEVRILAQRSAQAAKEIKALIESTVSSVASGSSQVRQASNAMTDIVSSVSDVTTIMSEITNAADEQMRGIHEI
NSAVAQLDTMVQQNAALVQESTAASAALQAQAADLTDTVNQFKI

Specific function: Acts as a receptor for citrate and mediates taxis away from phenol. Also mediates an attractant response to metal-citrate complexes [H]

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=328, Percent_Identity=51.219512195122, Blast_Score=269, Evalue=4e-73,
Organism=Escherichia coli, GI1787690, Length=325, Percent_Identity=47.6923076923077, Blast_Score=266, Evalue=2e-72,
Organism=Escherichia coli, GI1788195, Length=306, Percent_Identity=53.5947712418301, Blast_Score=265, Evalue=6e-72,
Organism=Escherichia coli, GI1788194, Length=340, Percent_Identity=48.5294117647059, Blast_Score=262, Evalue=4e-71,
Organism=Escherichia coli, GI1789453, Length=318, Percent_Identity=38.0503144654088, Blast_Score=201, Evalue=1e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR003122
- InterPro:   IPR004091
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 62808; Mature: 62808

Theoretical pI: Translated: 4.65; Mature: 4.65

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFSFLLGHSMLDSIRSRILAACIIIVAGSLAINTFLNYSVANKYNNSAIDNTLTALTVSH
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHEEECC
SVSIAEWVASKTQMIMSLKDSALTADPLAALKQVAAAGGFINVYIGYADKTAIFSNPDGI
CHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCEEEEEEEECCCEEEECCCCCC
PADYDPTGRPWYLQAVNAGKPVVTPPYIDAGTQQLVVTFAWSIVQDGVLKGVIAADVTMG
CCCCCCCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SVIANVNAIHPTDNSFGMLIGADGTIIAHPETLLTLKPLADIAPNLNLQTLLTATVPVST
HHHHCCCEECCCCCCCEEEEECCCEEEECCHHHEEECCHHHHCCCCCHHEEEEEECCCCC
DISGSSKLLLAQAVPGTQWFTVVALDKSQATAGIHSLLTTSLVTLVIIIFISAGVIALIT
CCCCCCCEEEEECCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QRALTPLTHIQQAMDAISSGSADLTQRLPIEGRDEVAQIARSFNQFADKLSLVMAQIRGT
HHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
SESVRVAANEIAAGNQDLSGRTESAAASLQQTSAALEQISATVAQSASAARQANNAVFSA
CHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEC
SEDASRGGDVITKVITTMESIEKASGKIGDITSVIDGIAFQTNILALNAAVEAARAGEQG
CCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHEEHHHHHHHHHCCCCC
RGFAVVAGEVRILAQRSAQAAKEIKALIESTVSSVASGSSQVRQASNAMTDIVSSVSDVT
CCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
TIMSEITNAADEQMRGIHEINSAVAQLDTMVQQNAALVQESTAASAALQAQAADLTDTVN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QFKI
HHCC
>Mature Secondary Structure
MFSFLLGHSMLDSIRSRILAACIIIVAGSLAINTFLNYSVANKYNNSAIDNTLTALTVSH
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHEEECC
SVSIAEWVASKTQMIMSLKDSALTADPLAALKQVAAAGGFINVYIGYADKTAIFSNPDGI
CHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCEEEEEEEECCCEEEECCCCCC
PADYDPTGRPWYLQAVNAGKPVVTPPYIDAGTQQLVVTFAWSIVQDGVLKGVIAADVTMG
CCCCCCCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SVIANVNAIHPTDNSFGMLIGADGTIIAHPETLLTLKPLADIAPNLNLQTLLTATVPVST
HHHHCCCEECCCCCCCEEEEECCCEEEECCHHHEEECCHHHHCCCCCHHEEEEEECCCCC
DISGSSKLLLAQAVPGTQWFTVVALDKSQATAGIHSLLTTSLVTLVIIIFISAGVIALIT
CCCCCCCEEEEECCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QRALTPLTHIQQAMDAISSGSADLTQRLPIEGRDEVAQIARSFNQFADKLSLVMAQIRGT
HHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
SESVRVAANEIAAGNQDLSGRTESAAASLQQTSAALEQISATVAQSASAARQANNAVFSA
CHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEC
SEDASRGGDVITKVITTMESIEKASGKIGDITSVIDGIAFQTNILALNAAVEAARAGEQG
CCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHEEHHHHHHHHHCCCCC
RGFAVVAGEVRILAQRSAQAAKEIKALIESTVSSVASGSSQVRQASNAMTDIVSSVSDVT
CCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
TIMSEITNAADEQMRGIHEINSAVAQLDTMVQQNAALVQESTAASAALQAQAADLTDTVN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QFKI
HHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8419927; 11677609 [H]