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The map label for this gene is rtn [H]

Identifier: 22126786

GI number: 22126786

Start: 3213729

End: 3215201

Strand: Direct

Name: rtn [H]

Synonym: y2909

Alternate gene names: 22126786

Gene position: 3213729-3215201 (Clockwise)

Preceding gene: 22126785

Following gene: 22126787

Centisome position: 69.85

GC content: 42.84

Gene sequence:

>1473_bases
TTGTCATTACTGTATCGCAGCAGTGAAAATAAATTAACAACACAAAGTGGTAATATTATCACCTATGCCTCTCATTTCCT
TAATGAAATAACAACGACCATGTCTCAGCTTATCCCACTGAGCACCCAATCGTGCGAACAAGCCAGCCCAACTCTTCATT
ATCGTGCCGCCTTTACCAATGGTGTCAGAGCCTTTTTATTGGTCAGGGAAGGCGTTGCTTATTGCTCCTCGGCAACGGGT
GAAATGCACACGCCAGTCAGTACGATCTACCCCAAAGTTAATTTATCCCAGCCACTGGATTTTAAAATTCAGCAAGGCCC
CCCCATGATGCCAAACAAGCCTGCAATTGCCGTATGGCTGCGTCAAGCAGGCCGTGGAGATACGGGAATATTGGCGACGA
TGGAATTCAGTTTGCATCCCTATCTATTAATGGGCCGTTCAGATAACGAAATGAGTGGCTCAGCGATTATTATTGATGGC
TTAGCTATCACTACTTTTGATTCTAACGTCTTACCTATCAGCCAGTTACCTAATCTAAACGCCAGGGAGATTACATTACC
TGGTTATCCGATTAAGATATTGATTTATCATAATAGTATAACGAAAAACGATATTAGAATGACCCTGTTAGGTGGCCTAT
TACTTGCCGGCTTGGTGGGCATCTTGGCTTATTATATTTTAATCACCAAAAAAAGTGCTGAAGCTGAAATTTTACGGGGC
ATTAGGCGCGGTGAGTTTTTCGTTGAATATCAACCGGTTTTTCGCTCACATAATCAGACAATATCAGGTTTAGAAGCCCT
TATCCGTTGGCAACACCCGACTGAAGGGCGGATTTCGCCCGATATCTTCATTCCTTATGCCGAAACTCAACACCTGATAC
AGCCGCTGACAACGCACTTGTTTGAGTTAATTATCAGAGATACCGCTCTTATGGTAAACCTGTTCCCGACGGGCGCTAAA
CTTGCCTTTAATATTTCACCGGCCCATCTTGCTGATGATGATTTTTGTCAGGACGTATCACGACTCTTGCAGCAATTAAA
TACCGATATTTTTACCCCCGTATTCGAAATTACTGAGCGAGGTATGGTGCAAAAAGAGTTGGCCCTGAAGCAATTCGCCT
GGCTGCATTCGCAAGGGATTCAAATCGCTGTCGATGATTTTGGCACCGGCCATAGCGCCCTGATCTATTTAGAACGCTTT
ACCTTAGATTATATTAAAATTGATCGCGGCTTTATCAGCACGATAGGCGAAAATACGGTGACAACGCCGGTATTAGATTC
GGTATTAATTCTGGCAAAAAAACTTAATATTGAAACTATCGCTGAGGGCATCGAGACTGAGCAACAACTTCACTATTTAG
CTAAACATGGTGTCAATTACTTGCAGGGTTATTTACTCAGTAAGCCGCTGTCTGTTGAAGCTTTAGCTAAATTCTGTCAT
GAAAAGATGAGTAACAAAAACTTACTGGCTTAA

Upstream 100 bases:

>100_bases
AACAGTGCGTTCTCCCGCAATATTTTGTCCAGACGCCATCTGGTAAAAAAAGAGTATCCTCCTCGCGCTCTGCTTTTTTA
TCTGTTTTGTCGTTATAACG

Downstream 100 bases:

>100_bases
TGTTTGCATTATCCCCCTGTAAGCTGGTAATTTCATTTGAGAAAATGATTATCTGCAGCTTCGCAGGAGATTGCCAACAA
TATGTTTTTACGCCTATTTG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 490; Mature: 489

Protein sequence:

>490_residues
MSLLYRSSENKLTTQSGNIITYASHFLNEITTTMSQLIPLSTQSCEQASPTLHYRAAFTNGVRAFLLVREGVAYCSSATG
EMHTPVSTIYPKVNLSQPLDFKIQQGPPMMPNKPAIAVWLRQAGRGDTGILATMEFSLHPYLLMGRSDNEMSGSAIIIDG
LAITTFDSNVLPISQLPNLNAREITLPGYPIKILIYHNSITKNDIRMTLLGGLLLAGLVGILAYYILITKKSAEAEILRG
IRRGEFFVEYQPVFRSHNQTISGLEALIRWQHPTEGRISPDIFIPYAETQHLIQPLTTHLFELIIRDTALMVNLFPTGAK
LAFNISPAHLADDDFCQDVSRLLQQLNTDIFTPVFEITERGMVQKELALKQFAWLHSQGIQIAVDDFGTGHSALIYLERF
TLDYIKIDRGFISTIGENTVTTPVLDSVLILAKKLNIETIAEGIETEQQLHYLAKHGVNYLQGYLLSKPLSVEALAKFCH
EKMSNKNLLA

Sequences:

>Translated_490_residues
MSLLYRSSENKLTTQSGNIITYASHFLNEITTTMSQLIPLSTQSCEQASPTLHYRAAFTNGVRAFLLVREGVAYCSSATG
EMHTPVSTIYPKVNLSQPLDFKIQQGPPMMPNKPAIAVWLRQAGRGDTGILATMEFSLHPYLLMGRSDNEMSGSAIIIDG
LAITTFDSNVLPISQLPNLNAREITLPGYPIKILIYHNSITKNDIRMTLLGGLLLAGLVGILAYYILITKKSAEAEILRG
IRRGEFFVEYQPVFRSHNQTISGLEALIRWQHPTEGRISPDIFIPYAETQHLIQPLTTHLFELIIRDTALMVNLFPTGAK
LAFNISPAHLADDDFCQDVSRLLQQLNTDIFTPVFEITERGMVQKELALKQFAWLHSQGIQIAVDDFGTGHSALIYLERF
TLDYIKIDRGFISTIGENTVTTPVLDSVLILAKKLNIETIAEGIETEQQLHYLAKHGVNYLQGYLLSKPLSVEALAKFCH
EKMSNKNLLA
>Mature_489_residues
SLLYRSSENKLTTQSGNIITYASHFLNEITTTMSQLIPLSTQSCEQASPTLHYRAAFTNGVRAFLLVREGVAYCSSATGE
MHTPVSTIYPKVNLSQPLDFKIQQGPPMMPNKPAIAVWLRQAGRGDTGILATMEFSLHPYLLMGRSDNEMSGSAIIIDGL
AITTFDSNVLPISQLPNLNAREITLPGYPIKILIYHNSITKNDIRMTLLGGLLLAGLVGILAYYILITKKSAEAEILRGI
RRGEFFVEYQPVFRSHNQTISGLEALIRWQHPTEGRISPDIFIPYAETQHLIQPLTTHLFELIIRDTALMVNLFPTGAKL
AFNISPAHLADDDFCQDVSRLLQQLNTDIFTPVFEITERGMVQKELALKQFAWLHSQGIQIAVDDFGTGHSALIYLERFT
LDYIKIDRGFISTIGENTVTTPVLDSVLILAKKLNIETIAEGIETEQQLHYLAKHGVNYLQGYLLSKPLSVEALAKFCHE
KMSNKNLLA

Specific function: Involved in resistance to phages N4 and lambda [H]

COG id: COG2200

COG function: function code T; FOG: EAL domain

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 EAL domain [H]

Homologues:

Organism=Escherichia coli, GI1788502, Length=477, Percent_Identity=42.7672955974843, Blast_Score=438, Evalue=1e-124,
Organism=Escherichia coli, GI87081980, Length=489, Percent_Identity=29.038854805726, Blast_Score=209, Evalue=4e-55,
Organism=Escherichia coli, GI87081845, Length=485, Percent_Identity=29.4845360824742, Blast_Score=179, Evalue=4e-46,
Organism=Escherichia coli, GI1786507, Length=227, Percent_Identity=34.8017621145374, Blast_Score=144, Evalue=1e-35,
Organism=Escherichia coli, GI1787541, Length=251, Percent_Identity=33.4661354581673, Blast_Score=142, Evalue=3e-35,
Organism=Escherichia coli, GI87081743, Length=272, Percent_Identity=29.4117647058824, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI1790496, Length=257, Percent_Identity=28.0155642023346, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI87081921, Length=242, Percent_Identity=28.9256198347107, Blast_Score=108, Evalue=5e-25,
Organism=Escherichia coli, GI1788849, Length=235, Percent_Identity=28.936170212766, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI87082096, Length=231, Percent_Identity=29.004329004329, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI226510982, Length=252, Percent_Identity=28.5714285714286, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1787055, Length=252, Percent_Identity=31.7460317460317, Blast_Score=92, Evalue=6e-20,
Organism=Escherichia coli, GI1787410, Length=137, Percent_Identity=27.7372262773723, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001633 [H]

Pfam domain/function: PF00563 EAL [H]

EC number: NA

Molecular weight: Translated: 54637; Mature: 54506

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: PS50883 EAL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLLYRSSENKLTTQSGNIITYASHFLNEITTTMSQLIPLSTQSCEQASPTLHYRAAFTN
CCCEEECCCCCEEECCCCEEEHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCEEEEEHHHC
GVRAFLLVREGVAYCSSATGEMHTPVSTIYPKVNLSQPLDFKIQQGPPMMPNKPAIAVWL
CHHEEHHHHHHHHHHCCCCCCCCCCHHHHCCCCCCCCCCCEEECCCCCCCCCCCHHEEEE
RQAGRGDTGILATMEFSLHPYLLMGRSDNEMSGSAIIIDGLAITTFDSNVLPISQLPNLN
HHCCCCCCCEEEEEEECCCCEEEEECCCCCCCCCEEEEECEEEEEECCCCEEHHHCCCCC
AREITLPGYPIKILIYHNSITKNDIRMTLLGGLLLAGLVGILAYYILITKKSAEAEILRG
CCEEECCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
IRRGEFFVEYQPVFRSHNQTISGLEALIRWQHPTEGRISPDIFIPYAETQHLIQPLTTHL
HHCCCEEEEEEHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCEEEECHHHHHHHHHHHHHH
FELIIRDTALMVNLFPTGAKLAFNISPAHLADDDFCQDVSRLLQQLNTDIFTPVFEITER
HHHHHHHHEEEEEEECCCCEEEEECCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHC
GMVQKELALKQFAWLHSQGIQIAVDDFGTGHSALIYLERFTLDYIKIDRGFISTIGENTV
CHHHHHHHHHHHHHHHCCCCEEEEECCCCCCEEEEEEEEHEEEEEEECCHHHHHCCCCCC
TTPVLDSVLILAKKLNIETIAEGIETEQQLHYLAKHGVNYLQGYLLSKPLSVEALAKFCH
CHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCCHHHHHHHHH
EKMSNKNLLA
HHHCCCCCCC
>Mature Secondary Structure 
SLLYRSSENKLTTQSGNIITYASHFLNEITTTMSQLIPLSTQSCEQASPTLHYRAAFTN
CCEEECCCCCEEECCCCEEEHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCEEEEEHHHC
GVRAFLLVREGVAYCSSATGEMHTPVSTIYPKVNLSQPLDFKIQQGPPMMPNKPAIAVWL
CHHEEHHHHHHHHHHCCCCCCCCCCHHHHCCCCCCCCCCCEEECCCCCCCCCCCHHEEEE
RQAGRGDTGILATMEFSLHPYLLMGRSDNEMSGSAIIIDGLAITTFDSNVLPISQLPNLN
HHCCCCCCCEEEEEEECCCCEEEEECCCCCCCCCEEEEECEEEEEECCCCEEHHHCCCCC
AREITLPGYPIKILIYHNSITKNDIRMTLLGGLLLAGLVGILAYYILITKKSAEAEILRG
CCEEECCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
IRRGEFFVEYQPVFRSHNQTISGLEALIRWQHPTEGRISPDIFIPYAETQHLIQPLTTHL
HHCCCEEEEEEHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCEEEECHHHHHHHHHHHHHH
FELIIRDTALMVNLFPTGAKLAFNISPAHLADDDFCQDVSRLLQQLNTDIFTPVFEITER
HHHHHHHHEEEEEEECCCCEEEEECCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHC
GMVQKELALKQFAWLHSQGIQIAVDDFGTGHSALIYLERFTLDYIKIDRGFISTIGENTV
CHHHHHHHHHHHHHHHCCCCEEEEECCCCCCEEEEEEEEHEEEEEEECCHHHHHCCCCCC
TTPVLDSVLILAKKLNIETIAEGIETEQQLHYLAKHGVNYLQGYLLSKPLSVEALAKFCH
CHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCCHHHHHHHHH
EKMSNKNLLA
HHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 9079933 [H]