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The map label for this gene is rpiA2 [H]

Identifier: 22126769

GI number: 22126769

Start: 3195496

End: 3196248

Strand: Reverse

Name: rpiA2 [H]

Synonym: y2892

Alternate gene names: 22126769

Gene position: 3196248-3195496 (Counterclockwise)

Preceding gene: 22126770

Following gene: 22126768

Centisome position: 69.47

GC content: 54.32

Gene sequence:

>753_bases
TTGGCGACCCCACCTTTATGTAGTCATGATCAGGAGTCACGAATGAGCAATCAACAAAATGACGCCAAGAGGGCTGCCGC
CCGTCGGGTGATTCAGGATTTCGTGTTCGATGGCATGACGTTGGGGCTGGGTTCCGGGACCACCTCGCATTTCTTTGTGC
GCGAACTGGGCCAGCATGTTGCCAAGGGCTTGCAGTTAACCTGCACCACAACTTCTCGTGCGACGAGCGAGGTGGCGCGT
GACGTGGGCATTGAGCTCTCGGATCCGAATGAGATGAATGAGATTGATCTGACCATCGACGGCCCAGATGAGATTGACCG
GCGGTTCAATATGATCAAGGGCGGTGGAGCCTGCCTTCTGTGGGAGAAAATTATCGCCCATGCCTCGAAGCGGATGATTT
GTATTTGTGATGAGACAAAAATCGTCAATTGCTTGGGGCAATTTCCGCTGCCAGTCGAAATCGTCCCCTTTGCCTGGAAA
CAGACCGAACGCAGGGTCGAGCGGGTACTCGCGGAACAGGGTCTCCATCATGTGCCGATTATTCGGCGTATGGGGGGCGG
GCACCCGGTGATCACTGACAGTGGAAACTTTATTCTGGATTGCCATTGCGGGGCGATTATCACGGCCCCTGAACCGCTGG
AAATAGAGCTTAATCGCATTCCGGGGGTGGTTGAAAACGGTCTTTTCACCCGTGAGGCTACCGGTATGGTGGTGGGCTAT
TTTGACGGTTCCTCCTACGTTCAACTGCGATAA

Upstream 100 bases:

>100_bases
ACGCGCGAACCCCCCAATCCCGCAACCGCGGCGGTTGTTGCTGAGGCCCAACGCATTTACCGTACTCTTTACCCGGCGCT
GAGAGAAACCTTCGCAGAAC

Downstream 100 bases:

>100_bases
TCACGGCCTTTTTCGACGCTGTCGCGAGTCGCGTCACCTTGGCACCAAGAGAGCAAAAGAGCAAAAGAGCAAAAGAGCAA
AAGAGAGTATCACAGCATGC

Product: ribose 5-phosphate isomerase A

Products: NA

Alternate protein names: Phosphoriboisomerase A 2; PRI 2 [H]

Number of amino acids: Translated: 250; Mature: 249

Protein sequence:

>250_residues
MATPPLCSHDQESRMSNQQNDAKRAAARRVIQDFVFDGMTLGLGSGTTSHFFVRELGQHVAKGLQLTCTTTSRATSEVAR
DVGIELSDPNEMNEIDLTIDGPDEIDRRFNMIKGGGACLLWEKIIAHASKRMICICDETKIVNCLGQFPLPVEIVPFAWK
QTERRVERVLAEQGLHHVPIIRRMGGGHPVITDSGNFILDCHCGAIITAPEPLEIELNRIPGVVENGLFTREATGMVVGY
FDGSSYVQLR

Sequences:

>Translated_250_residues
MATPPLCSHDQESRMSNQQNDAKRAAARRVIQDFVFDGMTLGLGSGTTSHFFVRELGQHVAKGLQLTCTTTSRATSEVAR
DVGIELSDPNEMNEIDLTIDGPDEIDRRFNMIKGGGACLLWEKIIAHASKRMICICDETKIVNCLGQFPLPVEIVPFAWK
QTERRVERVLAEQGLHHVPIIRRMGGGHPVITDSGNFILDCHCGAIITAPEPLEIELNRIPGVVENGLFTREATGMVVGY
FDGSSYVQLR
>Mature_249_residues
ATPPLCSHDQESRMSNQQNDAKRAAARRVIQDFVFDGMTLGLGSGTTSHFFVRELGQHVAKGLQLTCTTTSRATSEVARD
VGIELSDPNEMNEIDLTIDGPDEIDRRFNMIKGGGACLLWEKIIAHASKRMICICDETKIVNCLGQFPLPVEIVPFAWKQ
TERRVERVLAEQGLHHVPIIRRMGGGHPVITDSGNFILDCHCGAIITAPEPLEIELNRIPGVVENGLFTREATGMVVGYF
DGSSYVQLR

Specific function: Nonoxidative branch of the pentose phosphate pathway. [C]

COG id: COG0120

COG function: function code G; Ribose 5-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribose 5-phosphate isomerase family [H]

Homologues:

Organism=Homo sapiens, GI94536842, Length=236, Percent_Identity=36.4406779661017, Blast_Score=128, Evalue=5e-30,
Organism=Escherichia coli, GI1789280, Length=231, Percent_Identity=38.0952380952381, Blast_Score=142, Evalue=3e-35,
Organism=Caenorhabditis elegans, GI17551758, Length=230, Percent_Identity=35.2173913043478, Blast_Score=120, Evalue=8e-28,
Organism=Saccharomyces cerevisiae, GI6324669, Length=250, Percent_Identity=34.4, Blast_Score=122, Evalue=6e-29,
Organism=Drosophila melanogaster, GI281364072, Length=222, Percent_Identity=34.2342342342342, Blast_Score=114, Evalue=8e-26,

Paralogues:

None

Copy number: 740 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004788
- InterPro:   IPR020672 [H]

Pfam domain/function: PF06026 Rib_5-P_isom_A [H]

EC number: =5.3.1.6 [H]

Molecular weight: Translated: 27588; Mature: 27457

Theoretical pI: Translated: 5.85; Mature: 5.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.2 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATPPLCSHDQESRMSNQQNDAKRAAARRVIQDFVFDGMTLGLGSGTTSHFFVRELGQHV
CCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHHHH
AKGLQLTCTTTSRATSEVARDVGIELSDPNEMNEIDLTIDGPDEIDRRFNMIKGGGACLL
HCCEEEEEECCHHHHHHHHHHCCCEECCCCCCCEEEEEECCHHHHHHHHHHHCCCCCHHH
WEKIIAHASKRMICICDETKIVNCLGQFPLPVEIVPFAWKQTERRVERVLAEQGLHHVPI
HHHHHHHCCCCEEEEECCHHHHHHHCCCCCCEEEECCHHHHHHHHHHHHHHHCCCCCCCH
IRRMGGGHPVITDSGNFILDCHCGAIITAPEPLEIELNRIPGVVENGLFTREATGMVVGY
HHHCCCCCEEEECCCCEEEEECCCEEEECCCCCEEECCCCCCHHHCCCEEEECCCEEEEE
FDGSSYVQLR
ECCCCEEEEC
>Mature Secondary Structure 
ATPPLCSHDQESRMSNQQNDAKRAAARRVIQDFVFDGMTLGLGSGTTSHFFVRELGQHV
CCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHHHH
AKGLQLTCTTTSRATSEVARDVGIELSDPNEMNEIDLTIDGPDEIDRRFNMIKGGGACLL
HCCEEEEEECCHHHHHHHHHHCCCEECCCCCCCEEEEEECCHHHHHHHHHHHCCCCCHHH
WEKIIAHASKRMICICDETKIVNCLGQFPLPVEIVPFAWKQTERRVERVLAEQGLHHVPI
HHHHHHHCCCCEEEEECCHHHHHHHCCCCCCEEEECCHHHHHHHHHHHHHHHCCCCCCCH
IRRMGGGHPVITDSGNFILDCHCGAIITAPEPLEIELNRIPGVVENGLFTREATGMVVGY
HHHCCCCCEEEECCCCEEEEECCCEEEECCCCCEEECCCCCCHHHCCCEEEECCCEEEEE
FDGSSYVQLR
ECCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430 [H]