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The map label for this gene is pcbC [H]

Identifier: 22126745

GI number: 22126745

Start: 3166483

End: 3167412

Strand: Reverse

Name: pcbC [H]

Synonym: y2868

Alternate gene names: 22126745

Gene position: 3167412-3166483 (Counterclockwise)

Preceding gene: 22126746

Following gene: 22126744

Centisome position: 68.85

GC content: 54.19

Gene sequence:

>930_bases
TTGCGCCATGCGGCGCGGGATGTCGGTTTTTTTTATCTGACCGGGCACGGCATTGATACCTCGTTACTACGGCAGATACA
AATCCTATCACGGCAGTTCTTTGCGCTGAGCGATGAAGAAAAACTGTCAATCGCCATGATTCGCTCCCCACATTTTCGCG
GCTATAACCGTGCTGCTTCGGAATTCACCCGTGGTCAGCCAGATTGGCGCGAGCAATTCGACATTGGTGCTGAAAGAACC
CCATTACCACAAATCGCAGGCGCACCCAGTTGGACACGGCTGCAAGGCCCGAACCAATGGCCAACCGCACTGCCAGAATT
AAAACCTGTGTTATTGCAGTGGCAAGAGGAGATGACCCGCATGTCACTGCGCCTCCTGCGGGCATTCGCACTGGCATTGG
ATCTGGATGAGCAGGCTTTTGATGCGTTGTACGGTGATAAACCCAATGAACATATCAAGCTGATTCGTTATCCAGGGCGG
GAGGCGACCCAAAGTGGGCAGGGGGTTGGTGCGCACAAAGATTCGGGTTTCCTTAGCTTCTTACTGCAAGACACGCAACG
CGGTTTACAAGTCGAAGTGGAAGAGGGCCAATGGATTGATGCCGTACCGCGTGAAGGCACTTTTGTGGTGAATATCGGTG
AGTTGTTGGAACTGGCCAGTAATGGTTACTTGCGTGCCACCGTACACCGGGTGGAAACCCCACCCGCCGGGATTGACCGC
CTGTCTATTGCCTTCTTTTTAGGTGCGCGTTTGGATGCGGTGGTGCCACTGTATCCATTATCTGCCGCATTGGCGGCGGA
AGCTCGTGGGCCAGCCAGTGATCCGCACAACCCGTTGTTCCGTGATGTTGGGCTGAATTATCTCAAGGGGCGTTTGCGGT
CACATCCCGATGTGGCGGAGCGGTATTACTCCGATGCCCTTTGTTCTTGA

Upstream 100 bases:

>100_bases
CCAATGGCTGGCGAATCAGTCAGCGACCAGCACATTACCGCTACTGGATCTTTCACTACTCAGTGGCAGTGATACCGAAC
GCCAGGCATTTTTAACGGCC

Downstream 100 bases:

>100_bases
AGTGGTAGGAGTGTTAGCTGCACGCACTTACCCGAATCACTGACGTGAGTCAGCTCATCGGGATTCGTTTGCTGGCTGCC
TACCTACCACTCCAATAACT

Product: iron/ascorbate-dependent oxidoreductase

Products: NA

Alternate protein names: IPNS [H]

Number of amino acids: Translated: 309; Mature: 309

Protein sequence:

>309_residues
MRHAARDVGFFYLTGHGIDTSLLRQIQILSRQFFALSDEEKLSIAMIRSPHFRGYNRAASEFTRGQPDWREQFDIGAERT
PLPQIAGAPSWTRLQGPNQWPTALPELKPVLLQWQEEMTRMSLRLLRAFALALDLDEQAFDALYGDKPNEHIKLIRYPGR
EATQSGQGVGAHKDSGFLSFLLQDTQRGLQVEVEEGQWIDAVPREGTFVVNIGELLELASNGYLRATVHRVETPPAGIDR
LSIAFFLGARLDAVVPLYPLSAALAAEARGPASDPHNPLFRDVGLNYLKGRLRSHPDVAERYYSDALCS

Sequences:

>Translated_309_residues
MRHAARDVGFFYLTGHGIDTSLLRQIQILSRQFFALSDEEKLSIAMIRSPHFRGYNRAASEFTRGQPDWREQFDIGAERT
PLPQIAGAPSWTRLQGPNQWPTALPELKPVLLQWQEEMTRMSLRLLRAFALALDLDEQAFDALYGDKPNEHIKLIRYPGR
EATQSGQGVGAHKDSGFLSFLLQDTQRGLQVEVEEGQWIDAVPREGTFVVNIGELLELASNGYLRATVHRVETPPAGIDR
LSIAFFLGARLDAVVPLYPLSAALAAEARGPASDPHNPLFRDVGLNYLKGRLRSHPDVAERYYSDALCS
>Mature_309_residues
MRHAARDVGFFYLTGHGIDTSLLRQIQILSRQFFALSDEEKLSIAMIRSPHFRGYNRAASEFTRGQPDWREQFDIGAERT
PLPQIAGAPSWTRLQGPNQWPTALPELKPVLLQWQEEMTRMSLRLLRAFALALDLDEQAFDALYGDKPNEHIKLIRYPGR
EATQSGQGVGAHKDSGFLSFLLQDTQRGLQVEVEEGQWIDAVPREGTFVVNIGELLELASNGYLRATVHRVETPPAGIDR
LSIAFFLGARLDAVVPLYPLSAALAAEARGPASDPHNPLFRDVGLNYLKGRLRSHPDVAERYYSDALCS

Specific function: Removes, in the presence of oxygen, 4 hydrogen atoms from delta-L-(alpha-aminoadipyl)-L-cysteinyl-D-valine (ACV) to form the azetidinone and thiazolidine rings of isopenicillin [H]

COG id: COG3491

COG function: function code R; Isopenicillin N synthase and related dioxygenases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 Fe2OG dioxygenase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002057
- InterPro:   IPR002283
- InterPro:   IPR005123 [H]

Pfam domain/function: PF03171 2OG-FeII_Oxy [H]

EC number: =1.21.3.1 [H]

Molecular weight: Translated: 34607; Mature: 34607

Theoretical pI: Translated: 6.32; Mature: 6.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRHAARDVGFFYLTGHGIDTSLLRQIQILSRQFFALSDEEKLSIAMIRSPHFRGYNRAAS
CCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCHHHHH
EFTRGQPDWREQFDIGAERTPLPQIAGAPSWTRLQGPNQWPTALPELKPVLLQWQEEMTR
HHHCCCCCHHHHHCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
MSLRLLRAFALALDLDEQAFDALYGDKPNEHIKLIRYPGREATQSGQGVGAHKDSGFLSF
HHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCEEEEECCCCHHCCCCCCCCCCCCCHHHHH
LLQDTQRGLQVEVEEGQWIDAVPREGTFVVNIGELLELASNGYLRATVHRVETPPAGIDR
HHHHHCCCCEEEECCCCEEECCCCCCEEEEEHHHHHHHHCCCEEEEEEEECCCCCCCCHH
LSIAFFLGARLDAVVPLYPLSAALAAEARGPASDPHNPLFRDVGLNYLKGRLRSHPDVAE
HHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCHHHHHCHHHHHHHHCCCCHHHH
RYYSDALCS
HHHHHHCCC
>Mature Secondary Structure
MRHAARDVGFFYLTGHGIDTSLLRQIQILSRQFFALSDEEKLSIAMIRSPHFRGYNRAAS
CCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCHHHHH
EFTRGQPDWREQFDIGAERTPLPQIAGAPSWTRLQGPNQWPTALPELKPVLLQWQEEMTR
HHHCCCCCHHHHHCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
MSLRLLRAFALALDLDEQAFDALYGDKPNEHIKLIRYPGREATQSGQGVGAHKDSGFLSF
HHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCEEEEECCCCHHCCCCCCCCCCCCCHHHHH
LLQDTQRGLQVEVEEGQWIDAVPREGTFVVNIGELLELASNGYLRATVHRVETPPAGIDR
HHHHHCCCCEEEECCCCEEECCCCCCEEEEEHHHHHHHHCCCEEEEEEEECCCCCCCCHH
LSIAFFLGARLDAVVPLYPLSAALAAEARGPASDPHNPLFRDVGLNYLKGRLRSHPDVAE
HHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCHHHHHCHHHHHHHHCCCCHHHH
RYYSDALCS
HHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3130293 [H]