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The map label for this gene is 22126711

Identifier: 22126711

GI number: 22126711

Start: 3136458

End: 3137318

Strand: Reverse

Name: 22126711

Synonym: y2834

Alternate gene names: NA

Gene position: 3137318-3136458 (Counterclockwise)

Preceding gene: 22126712

Following gene: 22126704

Centisome position: 68.19

GC content: 49.01

Gene sequence:

>861_bases
ATGGCGGAGCCAGACATGAACCAAGGCGCGTTATTGGCTATTCTCGCCTCCCTGATTTTCAGCGTGATGAATGTGTTAGT
CAAAACCATCGCTGATGAAATTCCTACCGGTGAGATCGTATTCTTCCGCAGTAGCATTGGTTGCTTGTTGATTGGGTTAC
TGATGTATCAGCGTGGGATAGCGTTCAGCCGTGAAGATCGCCCATTGTTGGTACTCCGGGGGACGATGGGCGCACTGTAT
CTGATTTGCTATTTTTACAGTATTGCTCACCTGACATTGGCAGATGCCAGCATGTTGGCCTATCTGTCACCGTTTTTCTC
GATTGTGCTGTCATTATTAGTGTTGCGCGAACGGGTGAATGCCACCATGGCTTTCTGGTTGGTGATGGTGATTATTGGCG
CGATTATCTTGATCCGCCCGTGGAATTTTTCCACCTATACGTTGGCGTCTCTGGTGGGGGTGATGAGTGCGGTATTTGCG
GCTATTGCTTATTTGTCGGTGAATAAGCTCACGAAGCGCCATCACAATTATGAAATCGTCTTCTACTTTTTGTTTATCGC
GACGCTGATCTCTATCCCACTGATGTGGCATAACTTTGTTTGGCCGAGTGGGTATCAGTTCGGCATTCTCATCGCCATTG
CTCTTGTCTCATTGCTAGGTCAGGTGGTTTTAACGCAGGCTTTCTCTTCGGACAACCTGATCGTGGTGTCGGTGGTGCGC
TATATCGGCATTGTCTTCAATATTACCTGGGGCTGGCTATTTTGGGATGAGGTGCCATTGATGTTGTCGTTGATGGGGGG
CGGGTTGGTGGTGGTATCGTGCATTCAGTTGGGGTTACGCAGTAAAAAGAAGGCGGCCTGA

Upstream 100 bases:

>100_bases
AGGCGCTCAAGGCGTTTATTGACCGGGTCGGTGAGGAACATTGCCATCCCTCTTTATTGGGGGACGATTGTGACAGGCAG
GCGGCCATCATCGAACAACA

Downstream 100 bases:

>100_bases
TATTCACACAAGGCAAACTGATCGTTATACCCCAAATAATTCGAGTGGCAGGAAGGCAGCCAACGCATAGGCAGCTTGAA
GCATGACGGTTAGATAAGGC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 286; Mature: 285

Protein sequence:

>286_residues
MAEPDMNQGALLAILASLIFSVMNVLVKTIADEIPTGEIVFFRSSIGCLLIGLLMYQRGIAFSREDRPLLVLRGTMGALY
LICYFYSIAHLTLADASMLAYLSPFFSIVLSLLVLRERVNATMAFWLVMVIIGAIILIRPWNFSTYTLASLVGVMSAVFA
AIAYLSVNKLTKRHHNYEIVFYFLFIATLISIPLMWHNFVWPSGYQFGILIAIALVSLLGQVVLTQAFSSDNLIVVSVVR
YIGIVFNITWGWLFWDEVPLMLSLMGGGLVVVSCIQLGLRSKKKAA

Sequences:

>Translated_286_residues
MAEPDMNQGALLAILASLIFSVMNVLVKTIADEIPTGEIVFFRSSIGCLLIGLLMYQRGIAFSREDRPLLVLRGTMGALY
LICYFYSIAHLTLADASMLAYLSPFFSIVLSLLVLRERVNATMAFWLVMVIIGAIILIRPWNFSTYTLASLVGVMSAVFA
AIAYLSVNKLTKRHHNYEIVFYFLFIATLISIPLMWHNFVWPSGYQFGILIAIALVSLLGQVVLTQAFSSDNLIVVSVVR
YIGIVFNITWGWLFWDEVPLMLSLMGGGLVVVSCIQLGLRSKKKAA
>Mature_285_residues
AEPDMNQGALLAILASLIFSVMNVLVKTIADEIPTGEIVFFRSSIGCLLIGLLMYQRGIAFSREDRPLLVLRGTMGALYL
ICYFYSIAHLTLADASMLAYLSPFFSIVLSLLVLRERVNATMAFWLVMVIIGAIILIRPWNFSTYTLASLVGVMSAVFAA
IAYLSVNKLTKRHHNYEIVFYFLFIATLISIPLMWHNFVWPSGYQFGILIAIALVSLLGQVVLTQAFSSDNLIVVSVVRY
IGIVFNITWGWLFWDEVPLMLSLMGGGLVVVSCIQLGLRSKKKAA

Specific function: Unknown

COG id: COG0697

COG function: function code GER; Permeases of the drug/metabolite transporter (DMT) superfamily

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 2 DUF6 domains [H]

Homologues:

Organism=Homo sapiens, GI197927233, Length=303, Percent_Identity=24.7524752475248, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI23397492, Length=295, Percent_Identity=25.0847457627119, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24645940, Length=297, Percent_Identity=28.2828282828283, Blast_Score=95, Evalue=6e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000620 [H]

Pfam domain/function: PF00892 DUF6 [H]

EC number: NA

Molecular weight: Translated: 31808; Mature: 31677

Theoretical pI: Translated: 9.03; Mature: 9.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEPDMNQGALLAILASLIFSVMNVLVKTIADEIPTGEIVFFRSSIGCLLIGLLMYQRGI
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHCC
AFSREDRPLLVLRGTMGALYLICYFYSIAHLTLADASMLAYLSPFFSIVLSLLVLRERVN
CCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ATMAFWLVMVIIGAIILIRPWNFSTYTLASLVGVMSAVFAAIAYLSVNKLTKRHHNYEIV
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
FYFLFIATLISIPLMWHNFVWPSGYQFGILIAIALVSLLGQVVLTQAFSSDNLIVVSVVR
HHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
YIGIVFNITWGWLFWDEVPLMLSLMGGGLVVVSCIQLGLRSKKKAA
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
AEPDMNQGALLAILASLIFSVMNVLVKTIADEIPTGEIVFFRSSIGCLLIGLLMYQRGI
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHCC
AFSREDRPLLVLRGTMGALYLICYFYSIAHLTLADASMLAYLSPFFSIVLSLLVLRERVN
CCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ATMAFWLVMVIIGAIILIRPWNFSTYTLASLVGVMSAVFAAIAYLSVNKLTKRHHNYEIV
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
FYFLFIATLISIPLMWHNFVWPSGYQFGILIAIALVSLLGQVVLTQAFSSDNLIVVSVVR
HHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
YIGIVFNITWGWLFWDEVPLMLSLMGGGLVVVSCIQLGLRSKKKAA
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9252185 [H]