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The map label for this gene is mukE [H]

Identifier: 22126644

GI number: 22126644

Start: 3059204

End: 3059959

Strand: Reverse

Name: mukE [H]

Synonym: y2766

Alternate gene names: 22126644

Gene position: 3059959-3059204 (Counterclockwise)

Preceding gene: 22126645

Following gene: 22126643

Centisome position: 66.51

GC content: 47.35

Gene sequence:

>756_bases
ATGATTACGGAGCCAAGGTGCAGGCACATGTCATCAACAAATATTGAAGTAGTAATGCCCGTTAAGCTGGCTCAGGCATT
AGCCAACACATTATTTCCGGCATTAGACAGCCAGTTACGTGCTGGCCGTCATATTGGTATTGATGAGTTGGATAATCATG
CTTTTTTGATGGATTTTCAGGAGCAACTGGAAGAATTTTACGCTCGCTATAATGTCGAGTTAATCCGTGCGCCGGAAGGT
TTCTTCTATTTGCGTCCTCGTTCAACCACGCTTATTCCGCGCTCAGTTTTATCTGAGTTGGATATGATGGTCGGCAAAAT
TCTCTGTTATCTCTACCTCAGCCCGGAACGGCTGGCTCATGAAGGTATCTTCTCTCAGCAAGAGCTGTACGAAGAGTTAC
TGAGCCTGGCCGATGAGAGCAAATTGCTGAAGTTTGTTAACCAGCGCTCGACCGGGTCTGATTTGGATAAACAGAAGTTA
CAGGAAAAAGTCCGGACGTCACTTAACCGGCTGCGTCGGTTGGGCATGATTTATTTTATGGGCAACGACAGCACCAAGTT
TCGCATCACTGAAGCGGTATTCCGTTTTGGTGCGGATGTACGCAGCGGTGATGATCAACGTGAAGCCCAGCTACGCATGA
TCCGTGATGGCGAAGCCATGGCGGTAGAAAATAGTCTGTCACTTCATGATGAAAGTGATGATGCTGATGTCACCATGGGC
AATGCAGCGGACAGTGTAGAGGATGAACAGGAATGA

Upstream 100 bases:

>100_bases
CGTCATTTTGACGTGGCTCGTATCCTGGTCGACCAGGCTGTTCGCCTCGGTGTGGCCGAAGCCGATTTCTCAGGGTTGCC
AGCCGAATGGTTAGCAATCA

Downstream 100 bases:

>100_bases
TTGAACGCGGTAAATTTCGCTCACTGACCTTGGTTAACTGGAATGGTTTCTTTGCCCGAACATTCGATCTTGATGAGCTG
GTAACAACCCTCTCCGGCGG

Product: condesin subunit E

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 251; Mature: 251

Protein sequence:

>251_residues
MITEPRCRHMSSTNIEVVMPVKLAQALANTLFPALDSQLRAGRHIGIDELDNHAFLMDFQEQLEEFYARYNVELIRAPEG
FFYLRPRSTTLIPRSVLSELDMMVGKILCYLYLSPERLAHEGIFSQQELYEELLSLADESKLLKFVNQRSTGSDLDKQKL
QEKVRTSLNRLRRLGMIYFMGNDSTKFRITEAVFRFGADVRSGDDQREAQLRMIRDGEAMAVENSLSLHDESDDADVTMG
NAADSVEDEQE

Sequences:

>Translated_251_residues
MITEPRCRHMSSTNIEVVMPVKLAQALANTLFPALDSQLRAGRHIGIDELDNHAFLMDFQEQLEEFYARYNVELIRAPEG
FFYLRPRSTTLIPRSVLSELDMMVGKILCYLYLSPERLAHEGIFSQQELYEELLSLADESKLLKFVNQRSTGSDLDKQKL
QEKVRTSLNRLRRLGMIYFMGNDSTKFRITEAVFRFGADVRSGDDQREAQLRMIRDGEAMAVENSLSLHDESDDADVTMG
NAADSVEDEQE
>Mature_251_residues
MITEPRCRHMSSTNIEVVMPVKLAQALANTLFPALDSQLRAGRHIGIDELDNHAFLMDFQEQLEEFYARYNVELIRAPEG
FFYLRPRSTTLIPRSVLSELDMMVGKILCYLYLSPERLAHEGIFSQQELYEELLSLADESKLLKFVNQRSTGSDLDKQKL
QEKVRTSLNRLRRLGMIYFMGNDSTKFRITEAVFRFGADVRSGDDQREAQLRMIRDGEAMAVENSLSLHDESDDADVTMG
NAADSVEDEQE

Specific function: Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interactio

COG id: COG3095

COG function: function code D; Uncharacterized protein involved in chromosome partitioning

Gene ontology:

Cell location: Cytoplasm, nucleoid. Note=Restricted to the nucleoid region (By similarity) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mukE family [H]

Homologues:

Organism=Escherichia coli, GI226510932, Length=240, Percent_Identity=82.0833333333333, Blast_Score=404, Evalue=1e-114,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007385 [H]

Pfam domain/function: PF04288 MukE [H]

EC number: NA

Molecular weight: Translated: 28768; Mature: 28768

Theoretical pI: Translated: 4.60; Mature: 4.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITEPRCRHMSSTNIEVVMPVKLAQALANTLFPALDSQLRAGRHIGIDELDNHAFLMDFQ
CCCCCCHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCCCCHHHHHH
EQLEEFYARYNVELIRAPEGFFYLRPRSTTLIPRSVLSELDMMVGKILCYLYLSPERLAH
HHHHHHHHHCCEEEEECCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHH
EGIFSQQELYEELLSLADESKLLKFVNQRSTGSDLDKQKLQEKVRTSLNRLRRLGMIYFM
HCCCCHHHHHHHHHHHHCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCEEEEE
GNDSTKFRITEAVFRFGADVRSGDDQREAQLRMIRDGEAMAVENSLSLHDESDDADVTMG
CCCCCEEHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCEEEC
NAADSVEDEQE
CCCCCCCCCCC
>Mature Secondary Structure
MITEPRCRHMSSTNIEVVMPVKLAQALANTLFPALDSQLRAGRHIGIDELDNHAFLMDFQ
CCCCCCHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCCCCHHHHHH
EQLEEFYARYNVELIRAPEGFFYLRPRSTTLIPRSVLSELDMMVGKILCYLYLSPERLAH
HHHHHHHHHCCEEEEECCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHH
EGIFSQQELYEELLSLADESKLLKFVNQRSTGSDLDKQKLQEKVRTSLNRLRRLGMIYFM
HCCCCHHHHHHHHHHHHCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCEEEEE
GNDSTKFRITEAVFRFGADVRSGDDQREAQLRMIRDGEAMAVENSLSLHDESDDADVTMG
CCCCCEEHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCEEEC
NAADSVEDEQE
CCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430 [H]