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The map label for this gene is ompA [H]

Identifier: 22126613

GI number: 22126613

Start: 3019411

End: 3020502

Strand: Direct

Name: ompA [H]

Synonym: y2735

Alternate gene names: 22126613

Gene position: 3019411-3020502 (Clockwise)

Preceding gene: 22126612

Following gene: 22126614

Centisome position: 65.63

GC content: 49.82

Gene sequence:

>1092_bases
TTGCCTATTTGGATGATAATGAGGCGTAAAATGAAAAAGACAGCTATCGCATTAGCAGTGGCACTGGTAGGTTTCGCTAC
AGTAGCGCAAGCCGCACCAAAAGATAACACCTGGTACACCGGTGGTAAATTGGGTTGGTCTCAGTATCAAGATACTGGTT
CTATCATCAATAACGATGGTCCAACTCATAAAGATCAGCTGGGTGCCGGTGCGTTCTTCGGTTACCAAGCAAATCAGTAC
CTGGGCTTTGAGATGGGATACGACTGGCTTGGTCGTATGCCTTACAAAGGCGACATCAATAATGGCGCTTTCAAGGCTCA
AGGCGTTCAGTTAGCAGCTAAACTGAGCTACCCAGTAGCACAAGACCTTGACGTATATACCCGTCTGGGTGGTTTAGTAT
GGCGTGCAGATGCTAAAGGCTCCTTCGATGGTGGTCTTGACCGTGCTAGCGGCCATGATACCGGTGTTTCTCCATTGGTA
GCTCTGGGTGCTGAATACGCATGGACCAAAAACTGGGCAACCCGTATGGAATACCAGTGGGTTAACAACATCGGCGACCG
TGAAACCGTTGGTGCTCGTCCAGACAACGGCCTCCTGAGTGTTGGTGTTTCTTACCGCTTTGGTCAGGAAGATGCAGCAG
CGCCAATCGTTGCTCCAACACCTGCTCCAGCGCCAATTGTTGACACTAAGCGTTTCACATTAAAATCTGATGTGCTGTTT
GGTTTCAACAAAGCAAACCTGAAGCCAGAAGGCCAGCAAGCTCTGGACCAACTGTACGCACAACTGAGCTCTATCGATCC
TAAAGATGGTTCTGTAGTTGTTCTGGGCTTTGCTGACCGTATCGGTCAACCAGCGCCTAACTTAGCTCTGTCTCAGCGTC
GTGCTGACAGCGTGCGTGACTACCTGGTTTCTAAAGGTATCCCTGCTGACAAAATCACTGCTCGCGGTGAAGGTCAAGCA
AACCCAGTTACAGGCAACACCTGTGACAACGTGAAACCACGTGCTGCTCTGATTGAGTGCCTGGCACCAGATCGTCGCGT
AGAGATCGAAGTGAAAGGCTACAAAGAAGTTGTGACTCAGCCACAGGCTTAA

Upstream 100 bases:

>100_bases
AGGTTGCTCTAAAATGCCAAATCATACAGGCAACGTAATTAACGGGAGCGTAAAAACCTTGGCGAAGAATTTTAACCAAG
GGCTTAGCTTTTAAAGCTCA

Downstream 100 bases:

>100_bases
GTTAACTTCTTTCGTGAAAAACCCCGCGCTATGCGGGGTTTTTTTTGTGCCCAGAAAACCCCCAGCTAGGCTGGGGGTTC
AGTAAAGCTTTCAGCTTTGG

Product: outer membrane protein A

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 363; Mature: 362

Protein sequence:

>363_residues
MPIWMIMRRKMKKTAIALAVALVGFATVAQAAPKDNTWYTGGKLGWSQYQDTGSIINNDGPTHKDQLGAGAFFGYQANQY
LGFEMGYDWLGRMPYKGDINNGAFKAQGVQLAAKLSYPVAQDLDVYTRLGGLVWRADAKGSFDGGLDRASGHDTGVSPLV
ALGAEYAWTKNWATRMEYQWVNNIGDRETVGARPDNGLLSVGVSYRFGQEDAAAPIVAPTPAPAPIVDTKRFTLKSDVLF
GFNKANLKPEGQQALDQLYAQLSSIDPKDGSVVVLGFADRIGQPAPNLALSQRRADSVRDYLVSKGIPADKITARGEGQA
NPVTGNTCDNVKPRAALIECLAPDRRVEIEVKGYKEVVTQPQA

Sequences:

>Translated_363_residues
MPIWMIMRRKMKKTAIALAVALVGFATVAQAAPKDNTWYTGGKLGWSQYQDTGSIINNDGPTHKDQLGAGAFFGYQANQY
LGFEMGYDWLGRMPYKGDINNGAFKAQGVQLAAKLSYPVAQDLDVYTRLGGLVWRADAKGSFDGGLDRASGHDTGVSPLV
ALGAEYAWTKNWATRMEYQWVNNIGDRETVGARPDNGLLSVGVSYRFGQEDAAAPIVAPTPAPAPIVDTKRFTLKSDVLF
GFNKANLKPEGQQALDQLYAQLSSIDPKDGSVVVLGFADRIGQPAPNLALSQRRADSVRDYLVSKGIPADKITARGEGQA
NPVTGNTCDNVKPRAALIECLAPDRRVEIEVKGYKEVVTQPQA
>Mature_362_residues
PIWMIMRRKMKKTAIALAVALVGFATVAQAAPKDNTWYTGGKLGWSQYQDTGSIINNDGPTHKDQLGAGAFFGYQANQYL
GFEMGYDWLGRMPYKGDINNGAFKAQGVQLAAKLSYPVAQDLDVYTRLGGLVWRADAKGSFDGGLDRASGHDTGVSPLVA
LGAEYAWTKNWATRMEYQWVNNIGDRETVGARPDNGLLSVGVSYRFGQEDAAAPIVAPTPAPAPIVDTKRFTLKSDVLFG
FNKANLKPEGQQALDQLYAQLSSIDPKDGSVVVLGFADRIGQPAPNLALSQRRADSVRDYLVSKGIPADKITARGEGQAN
PVTGNTCDNVKPRAALIECLAPDRRVEIEVKGYKEVVTQPQA

Specific function: Required for the action of colicins K and L and for the stabilization of mating aggregates in conjugation. Serves as a receptor for a number of T-even like phages. Also acts as a porin with low permeability that allows slow penetration of small solutes [H

COG id: COG2885

COG function: function code M; Outer membrane protein and related peptidoglycan-associated (lipo)proteins

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 OmpA-like domain [H]

Homologues:

Organism=Escherichia coli, GI1787191, Length=353, Percent_Identity=73.371104815864, Blast_Score=518, Evalue=1e-148,
Organism=Escherichia coli, GI48994946, Length=120, Percent_Identity=35, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 3380 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1480 Molecules/Cell In: Growth Phase, Mi

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011250
- InterPro:   IPR006664
- InterPro:   IPR002368
- InterPro:   IPR006690
- InterPro:   IPR000498
- InterPro:   IPR006665 [H]

Pfam domain/function: PF00691 OmpA; PF01389 OmpA_membrane [H]

EC number: NA

Molecular weight: Translated: 39274; Mature: 39143

Theoretical pI: Translated: 8.85; Mature: 8.85

Prosite motif: PS01068 OMPA_1 ; PS51123 OMPA_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPIWMIMRRKMKKTAIALAVALVGFATVAQAAPKDNTWYTGGKLGWSQYQDTGSIINNDG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCCHHHHHCCCCEECCCC
PTHKDQLGAGAFFGYQANQYLGFEMGYDWLGRMPYKGDINNGAFKAQGVQLAAKLSYPVA
CCCHHHCCCCEEECCCCCCEEEHCCCHHHHCCCCCCCCCCCCCEEECCEEEEEEECCCCH
QDLDVYTRLGGLVWRADAKGSFDGGLDRASGHDTGVSPLVALGAEYAWTKNWATRMEYQW
HHHHHHHHHCCEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHCCCHHCCCCHHHHHHHHH
VNNIGDRETVGARPDNGLLSVGVSYRFGQEDAAAPIVAPTPAPAPIVDTKRFTLKSDVLF
HHCCCCCCCCCCCCCCCEEEECEEEEECCCCCCCCEEECCCCCCCCCCCCCEEEECCEEE
GFNKANLKPEGQQALDQLYAQLSSIDPKDGSVVVLGFADRIGQPAPNLALSQRRADSVRD
ECCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEECHHHCCCCCCCHHHHHHHHHHHHH
YLVSKGIPADKITARGEGQANPVTGNTCDNVKPRAALIECLAPDRRVEIEVKGYKEVVTQ
HHHHCCCCHHHEEECCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCEEEEEECCHHHHHCC
PQA
CCC
>Mature Secondary Structure 
PIWMIMRRKMKKTAIALAVALVGFATVAQAAPKDNTWYTGGKLGWSQYQDTGSIINNDG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCCHHHHHCCCCEECCCC
PTHKDQLGAGAFFGYQANQYLGFEMGYDWLGRMPYKGDINNGAFKAQGVQLAAKLSYPVA
CCCHHHCCCCEEECCCCCCEEEHCCCHHHHCCCCCCCCCCCCCEEECCEEEEEEECCCCH
QDLDVYTRLGGLVWRADAKGSFDGGLDRASGHDTGVSPLVALGAEYAWTKNWATRMEYQW
HHHHHHHHHCCEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHCCCHHCCCCHHHHHHHHH
VNNIGDRETVGARPDNGLLSVGVSYRFGQEDAAAPIVAPTPAPAPIVDTKRFTLKSDVLF
HHCCCCCCCCCCCCCCCEEEECEEEEECCCCCCCCEEECCCCCCCCCCCCCEEEECCEEE
GFNKANLKPEGQQALDQLYAQLSSIDPKDGSVVVLGFADRIGQPAPNLALSQRRADSVRD
ECCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEECHHHCCCCCCCHHHHHHHHHHHHH
YLVSKGIPADKITARGEGQANPVTGNTCDNVKPRAALIECLAPDRRVEIEVKGYKEVVTQ
HHHHCCCCHHHEEECCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCEEEEEECCHHHHHCC
PQA
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430 [H]