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The map label for this gene is rbsA1 [H]

Identifier: 22126376

GI number: 22126376

Start: 2754378

End: 2756021

Strand: Reverse

Name: rbsA1 [H]

Synonym: y2493

Alternate gene names: 22126376

Gene position: 2756021-2754378 (Counterclockwise)

Preceding gene: 22126377

Following gene: 22126375

Centisome position: 59.9

GC content: 51.22

Gene sequence:

>1644_bases
ATGAGTGGGACCAATCATAAACGATGCCGCTTAAGTGGCACGGGGCGTGTTGATGGAGGATCACCCATGGACGTTTCCAT
AGACCAACGCGCCATGGCGGCGCAAGAAAGTCAGGAGGGCGCTTTCCTCGTCATACACAACGTGCATAAACGCTACAATG
GCGTGCACGCACTGCGGGGAATTAACGTTGAGATTCATCAAGGTGAGATTTATCACTTACTGGGTGAGAACGGCTGTGGA
AAAAGCACGTTAATCAAGGTGATCTCCGGGGCTATTGGCGCGGATGAAGGTGAGTTGGTGATCAATGGCACGGTTCATCA
GCAATTAACCCCCATTGAGGCGCTGTCATTGGGGATTGAGACGGTTTATCAGGATCTCTCTCTTATCCCGAATTTAAGTG
TTGTCGAGAATATTGGATTAACCGAACAACTTGTCGCACAGGCAGGAAGATTAAACCGAATACTGGATCGCCAGCGCCTG
TTGTCCACCGCTAAAGCGGCATTAGCGGTGGTGGGGTTACCTTCCAACGAGCGTTTTTTGTTCACCACGGTAGAGGTACT
ACCGATGGCACAACGGCAACTGGTGGCAATTGCTCGAGCCATCGCCACTAAGGCCAGACTGGTTATCATGGATGAACCTA
CCACGTCACTGACAAAGAAGGAGATTGATAACCTGATTGGTGTCATTCGTCAGCTTGGTCAACAACATGTCGCCGTGCTG
TTTGTGAGCCACAAATTGGACGAATGTTTTGCCATTGGCGGCCAAGTCTTGGTGTTGAAAGATGGTCAGAAAATTGCTCA
AGGTGCCATCACCCATTTCACCCAGTCTCAATTAGGCTATTTAATGACCGGGCGACAGATGGATGAACGACGTTACCGTC
GAGTGCAGCAGGGGGGAGAGCCGCTGCTAACGGTTACGGCGTTAGGCCAACAGGCGGCTTTTGACGAGATATCCTTCGTG
TTACACCGCGGTGAAATTTTAGGCGTAACCGGATCACTTGATTCAGGGCGCAATGAACTCGGTTTGGCGTTAGCGGGAAT
ATTGCCGGCAAACCGTGGGAGCATCGCTCTCGAAGGTCAGCCGATTCGTCTTAGGCAACCCCGTGATGCCATTAACAACC
ACATTGCTTATGTGCCAGAAGATCGTCTTGATGCAGGCCTCTTCCTCAGTAAATCGATACTTGAGAACCTCATTGCACTC
GAACTGGATCACTTACTGGGCTATTGGGGGCAAGTGGATAAGGGGCAATGCCAGGTTTTAGCCACCCAGACGGTCCTCGA
TTTAGATATCTCTGCGCCGAATATCAACCTGCCGGTTCAGGCTCTTTCTGGTGGCAACCAACAACGGGTCCTCATTGGCA
GAGCACTGACCATCAAGCCGTGGGTGCTTATCTTGCATGGCCCCACCGTCGGCGTGGATATCGGCGCTAAAGATACGATT
TATCAGCTGATCCAAACGCTGGCGCAGCAAGGGATGGGGGTCATTCTGATCAGTGATGACCTACCGGAGCTGTGTCAAAA
CTGCGACCCAATCCTGGTGATGAAGAAAGGCCGTATTTGCCAACAGGTGAGCGCAGTGGATGCCAATGAAAATAGACTCT
ATCAAGCACAGATCGCCGATGAGGGACTCACTGAGGATTTATAG

Upstream 100 bases:

>100_bases
AGAACGTCGCCATCAGGAAAGGAAAAGGTGACGGTGTTTTGGTTATCGGTGATGCGGCAAAGTTTGTTGATAAGACCAAC
TGGCAGCAATACCCATTCTG

Downstream 100 bases:

>100_bases
CTATGGTTATTGATCTCCCCGCTCACTCGAAGCCATCACGCTCATTCAACGCCATCATCGCATGGTGCCTACAGCGGCCG
TCGACCTTTACCTTTATGTT

Product: ribose ABC transporter ATP binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 547; Mature: 546

Protein sequence:

>547_residues
MSGTNHKRCRLSGTGRVDGGSPMDVSIDQRAMAAQESQEGAFLVIHNVHKRYNGVHALRGINVEIHQGEIYHLLGENGCG
KSTLIKVISGAIGADEGELVINGTVHQQLTPIEALSLGIETVYQDLSLIPNLSVVENIGLTEQLVAQAGRLNRILDRQRL
LSTAKAALAVVGLPSNERFLFTTVEVLPMAQRQLVAIARAIATKARLVIMDEPTTSLTKKEIDNLIGVIRQLGQQHVAVL
FVSHKLDECFAIGGQVLVLKDGQKIAQGAITHFTQSQLGYLMTGRQMDERRYRRVQQGGEPLLTVTALGQQAAFDEISFV
LHRGEILGVTGSLDSGRNELGLALAGILPANRGSIALEGQPIRLRQPRDAINNHIAYVPEDRLDAGLFLSKSILENLIAL
ELDHLLGYWGQVDKGQCQVLATQTVLDLDISAPNINLPVQALSGGNQQRVLIGRALTIKPWVLILHGPTVGVDIGAKDTI
YQLIQTLAQQGMGVILISDDLPELCQNCDPILVMKKGRICQQVSAVDANENRLYQAQIADEGLTEDL

Sequences:

>Translated_547_residues
MSGTNHKRCRLSGTGRVDGGSPMDVSIDQRAMAAQESQEGAFLVIHNVHKRYNGVHALRGINVEIHQGEIYHLLGENGCG
KSTLIKVISGAIGADEGELVINGTVHQQLTPIEALSLGIETVYQDLSLIPNLSVVENIGLTEQLVAQAGRLNRILDRQRL
LSTAKAALAVVGLPSNERFLFTTVEVLPMAQRQLVAIARAIATKARLVIMDEPTTSLTKKEIDNLIGVIRQLGQQHVAVL
FVSHKLDECFAIGGQVLVLKDGQKIAQGAITHFTQSQLGYLMTGRQMDERRYRRVQQGGEPLLTVTALGQQAAFDEISFV
LHRGEILGVTGSLDSGRNELGLALAGILPANRGSIALEGQPIRLRQPRDAINNHIAYVPEDRLDAGLFLSKSILENLIAL
ELDHLLGYWGQVDKGQCQVLATQTVLDLDISAPNINLPVQALSGGNQQRVLIGRALTIKPWVLILHGPTVGVDIGAKDTI
YQLIQTLAQQGMGVILISDDLPELCQNCDPILVMKKGRICQQVSAVDANENRLYQAQIADEGLTEDL
>Mature_546_residues
SGTNHKRCRLSGTGRVDGGSPMDVSIDQRAMAAQESQEGAFLVIHNVHKRYNGVHALRGINVEIHQGEIYHLLGENGCGK
STLIKVISGAIGADEGELVINGTVHQQLTPIEALSLGIETVYQDLSLIPNLSVVENIGLTEQLVAQAGRLNRILDRQRLL
STAKAALAVVGLPSNERFLFTTVEVLPMAQRQLVAIARAIATKARLVIMDEPTTSLTKKEIDNLIGVIRQLGQQHVAVLF
VSHKLDECFAIGGQVLVLKDGQKIAQGAITHFTQSQLGYLMTGRQMDERRYRRVQQGGEPLLTVTALGQQAAFDEISFVL
HRGEILGVTGSLDSGRNELGLALAGILPANRGSIALEGQPIRLRQPRDAINNHIAYVPEDRLDAGLFLSKSILENLIALE
LDHLLGYWGQVDKGQCQVLATQTVLDLDISAPNINLPVQALSGGNQQRVLIGRALTIKPWVLILHGPTVGVDIGAKDTIY
QLIQTLAQQGMGVILISDDLPELCQNCDPILVMKKGRICQQVSAVDANENRLYQAQIADEGLTEDL

Specific function: Part of the ABC transporter complex RbsABCD involved in ribose import. Responsible for energy coupling to the transport system [H]

COG id: COG1129

COG function: function code G; ABC-type sugar transport system, ATPase component

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Homo sapiens, GI116734710, Length=304, Percent_Identity=26.3157894736842, Blast_Score=73, Evalue=7e-13,
Organism=Homo sapiens, GI105990541, Length=247, Percent_Identity=24.2914979757085, Blast_Score=67, Evalue=4e-11,
Organism=Escherichia coli, GI1790190, Length=498, Percent_Identity=34.5381526104418, Blast_Score=290, Evalue=2e-79,
Organism=Escherichia coli, GI1790525, Length=505, Percent_Identity=34.6534653465347, Blast_Score=279, Evalue=4e-76,
Organism=Escherichia coli, GI1788472, Length=509, Percent_Identity=33.7917485265226, Blast_Score=278, Evalue=5e-76,
Organism=Escherichia coli, GI48995001, Length=487, Percent_Identity=33.8809034907598, Blast_Score=271, Evalue=8e-74,
Organism=Escherichia coli, GI1788210, Length=502, Percent_Identity=34.4621513944223, Blast_Score=264, Evalue=8e-72,
Organism=Escherichia coli, GI1789991, Length=488, Percent_Identity=34.6311475409836, Blast_Score=262, Evalue=5e-71,
Organism=Escherichia coli, GI1787792, Length=503, Percent_Identity=33.9960238568588, Blast_Score=259, Evalue=3e-70,
Organism=Escherichia coli, GI1788897, Length=481, Percent_Identity=34.0956340956341, Blast_Score=254, Evalue=1e-68,
Organism=Escherichia coli, GI87081709, Length=230, Percent_Identity=31.304347826087, Blast_Score=106, Evalue=5e-24,
Organism=Escherichia coli, GI87081791, Length=242, Percent_Identity=28.5123966942149, Blast_Score=104, Evalue=2e-23,
Organism=Escherichia coli, GI1788506, Length=500, Percent_Identity=26.8, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI48994943, Length=506, Percent_Identity=25.098814229249, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI1787370, Length=240, Percent_Identity=28.3333333333333, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI1788225, Length=232, Percent_Identity=28.448275862069, Blast_Score=96, Evalue=5e-21,
Organism=Escherichia coli, GI1787712, Length=227, Percent_Identity=28.1938325991189, Blast_Score=93, Evalue=4e-20,
Organism=Escherichia coli, GI145693107, Length=564, Percent_Identity=24.645390070922, Blast_Score=90, Evalue=4e-19,
Organism=Escherichia coli, GI1789672, Length=241, Percent_Identity=26.5560165975104, Blast_Score=89, Evalue=6e-19,
Organism=Escherichia coli, GI1786563, Length=221, Percent_Identity=28.5067873303167, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI87082267, Length=263, Percent_Identity=26.9961977186312, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1787089, Length=242, Percent_Identity=28.9256198347107, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1786872, Length=222, Percent_Identity=28.8288288288288, Blast_Score=83, Evalue=5e-17,
Organism=Escherichia coli, GI1787029, Length=223, Percent_Identity=28.6995515695067, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI1790467, Length=230, Percent_Identity=30, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1788450, Length=226, Percent_Identity=28.7610619469027, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1789032, Length=217, Percent_Identity=25.3456221198157, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI1790544, Length=243, Percent_Identity=27.9835390946502, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1788761, Length=222, Percent_Identity=25.6756756756757, Blast_Score=77, Evalue=4e-15,
Organism=Escherichia coli, GI1787500, Length=227, Percent_Identity=27.7533039647577, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1789864, Length=236, Percent_Identity=22.4576271186441, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1787758, Length=222, Percent_Identity=28.3783783783784, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI87081834, Length=231, Percent_Identity=28.5714285714286, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1787164, Length=229, Percent_Identity=29.6943231441048, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1786253, Length=216, Percent_Identity=28.2407407407407, Blast_Score=73, Evalue=6e-14,
Organism=Escherichia coli, GI1789891, Length=217, Percent_Identity=27.6497695852535, Blast_Score=73, Evalue=6e-14,
Organism=Escherichia coli, GI1788165, Length=223, Percent_Identity=28.6995515695067, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1786319, Length=224, Percent_Identity=26.7857142857143, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1786398, Length=239, Percent_Identity=26.3598326359833, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1789593, Length=244, Percent_Identity=25, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1787143, Length=271, Percent_Identity=28.4132841328413, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI1789873, Length=234, Percent_Identity=26.9230769230769, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI1788644, Length=235, Percent_Identity=25.9574468085106, Blast_Score=69, Evalue=9e-13,
Organism=Escherichia coli, GI48994997, Length=237, Percent_Identity=26.5822784810127, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1787547, Length=233, Percent_Identity=26.6094420600858, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1786703, Length=207, Percent_Identity=27.536231884058, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1786345, Length=230, Percent_Identity=25.2173913043478, Blast_Score=66, Evalue=5e-12,
Organism=Escherichia coli, GI1786981, Length=269, Percent_Identity=28.996282527881, Blast_Score=66, Evalue=6e-12,
Organism=Escherichia coli, GI1787112, Length=225, Percent_Identity=30.6666666666667, Blast_Score=66, Evalue=6e-12,
Organism=Escherichia coli, GI1787759, Length=225, Percent_Identity=25.3333333333333, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI87081782, Length=225, Percent_Identity=27.1111111111111, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1789962, Length=263, Percent_Identity=27.7566539923954, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1790739, Length=232, Percent_Identity=29.7413793103448, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI87082268, Length=216, Percent_Identity=26.3888888888889, Blast_Score=64, Evalue=4e-11,
Organism=Escherichia coli, GI1787105, Length=215, Percent_Identity=26.046511627907, Blast_Score=63, Evalue=4e-11,
Organism=Escherichia coli, GI1789963, Length=226, Percent_Identity=26.9911504424779, Blast_Score=62, Evalue=7e-11,
Organism=Escherichia coli, GI1786654, Length=218, Percent_Identity=26.605504587156, Blast_Score=62, Evalue=7e-11,
Organism=Escherichia coli, GI1786803, Length=228, Percent_Identity=23.6842105263158, Blast_Score=62, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI17510237, Length=230, Percent_Identity=24.7826086956522, Blast_Score=68, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI115533608, Length=245, Percent_Identity=24.0816326530612, Blast_Score=68, Evalue=2e-11,
Organism=Drosophila melanogaster, GI116007184, Length=228, Percent_Identity=27.6315789473684, Blast_Score=76, Evalue=6e-14,
Organism=Drosophila melanogaster, GI221500365, Length=228, Percent_Identity=27.6315789473684, Blast_Score=75, Evalue=9e-14,
Organism=Drosophila melanogaster, GI28573571, Length=246, Percent_Identity=24.7967479674797, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI28573573, Length=246, Percent_Identity=24.7967479674797, Blast_Score=72, Evalue=9e-13,
Organism=Drosophila melanogaster, GI85725262, Length=322, Percent_Identity=26.0869565217391, Blast_Score=67, Evalue=4e-11,
Organism=Drosophila melanogaster, GI221512771, Length=247, Percent_Identity=23.8866396761134, Blast_Score=65, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR015861
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: =3.6.3.17 [H]

Molecular weight: Translated: 59311; Mature: 59180

Theoretical pI: Translated: 6.28; Mature: 6.28

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGTNHKRCRLSGTGRVDGGSPMDVSIDQRAMAAQESQEGAFLVIHNVHKRYNGVHALRG
CCCCCCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHCCCCCEEEEECHHHHHCCHHHEEC
INVEIHQGEIYHLLGENGCGKSTLIKVISGAIGADEGELVINGTVHQQLTPIEALSLGIE
CEEEEECCEEEEEECCCCCCHHHHHHHHHHHCCCCCCCEEEECCHHHHCCCHHHHHHHHH
TVYQDLSLIPNLSVVENIGLTEQLVAQAGRLNRILDRQRLLSTAKAALAVVGLPSNERFL
HHHHHHHHCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCEEE
FTTVEVLPMAQRQLVAIARAIATKARLVIMDEPTTSLTKKEIDNLIGVIRQLGQQHVAVL
EEEEEHHHHHHHHHHHHHHHHHCCEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCEEEEE
FVSHKLDECFAIGGQVLVLKDGQKIAQGAITHFTQSQLGYLMTGRQMDERRYRRVQQGGE
EEHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCC
PLLTVTALGQQAAFDEISFVLHRGEILGVTGSLDSGRNELGLALAGILPANRGSIALEGQ
CEEEEEECCCHHHHHHHHHHEECCEEEEEECCCCCCCCHHCEEEEEECCCCCCCEEECCC
PIRLRQPRDAINNHIAYVPEDRLDAGLFLSKSILENLIALELDHLLGYWGQVDKGQCQVL
CEEECCCHHHHCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEE
ATQTVLDLDISAPNINLPVQALSGGNQQRVLIGRALTIKPWVLILHGPTVGVDIGAKDTI
EEEEEEEEEECCCCCCCCCCCCCCCCCEEEEEEEEEEECCEEEEEECCEEEEECCCHHHH
YQLIQTLAQQGMGVILISDDLPELCQNCDPILVMKKGRICQQVSAVDANENRLYQAQIAD
HHHHHHHHHCCCEEEEECCCHHHHHHCCCCEEEEECCCHHHHHHHCCCCCCEEEEEEECC
EGLTEDL
CCCCCCC
>Mature Secondary Structure 
SGTNHKRCRLSGTGRVDGGSPMDVSIDQRAMAAQESQEGAFLVIHNVHKRYNGVHALRG
CCCCCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHCCCCCEEEEECHHHHHCCHHHEEC
INVEIHQGEIYHLLGENGCGKSTLIKVISGAIGADEGELVINGTVHQQLTPIEALSLGIE
CEEEEECCEEEEEECCCCCCHHHHHHHHHHHCCCCCCCEEEECCHHHHCCCHHHHHHHHH
TVYQDLSLIPNLSVVENIGLTEQLVAQAGRLNRILDRQRLLSTAKAALAVVGLPSNERFL
HHHHHHHHCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCEEE
FTTVEVLPMAQRQLVAIARAIATKARLVIMDEPTTSLTKKEIDNLIGVIRQLGQQHVAVL
EEEEEHHHHHHHHHHHHHHHHHCCEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCEEEEE
FVSHKLDECFAIGGQVLVLKDGQKIAQGAITHFTQSQLGYLMTGRQMDERRYRRVQQGGE
EEHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCC
PLLTVTALGQQAAFDEISFVLHRGEILGVTGSLDSGRNELGLALAGILPANRGSIALEGQ
CEEEEEECCCHHHHHHHHHHEECCEEEEEECCCCCCCCHHCEEEEEECCCCCCCEEECCC
PIRLRQPRDAINNHIAYVPEDRLDAGLFLSKSILENLIALELDHLLGYWGQVDKGQCQVL
CEEECCCHHHHCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEE
ATQTVLDLDISAPNINLPVQALSGGNQQRVLIGRALTIKPWVLILHGPTVGVDIGAKDTI
EEEEEEEEEECCCCCCCCCCCCCCCCCEEEEEEEEEEECCEEEEEECCEEEEECCCHHHH
YQLIQTLAQQGMGVILISDDLPELCQNCDPILVMKKGRICQQVSAVDANENRLYQAQIAD
HHHHHHHHHCCCEEEEECCCHHHHHHCCCCEEEEECCCHHHHHHHCCCCCCEEEEEEECC
EGLTEDL
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA