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The map label for this gene is fliR [H]

Identifier: 22126371

GI number: 22126371

Start: 2750452

End: 2751234

Strand: Direct

Name: fliR [H]

Synonym: y2488

Alternate gene names: 22126371

Gene position: 2750452-2751234 (Clockwise)

Preceding gene: 22126370

Following gene: 22126372

Centisome position: 59.78

GC content: 49.68

Gene sequence:

>783_bases
ATGCTGTCCTTTGATACCCACCAACTCAGCGTCTGGGTTAGCCAATACTTTTGGCCGTTGGTCCGGGTATTGGCCCTGAT
CGGCACCGCCCCGCTGTTGAGTGAGAAACAGATCAACAAAAAAGTGAAGATTGGGCTGGGGGTCTTAATTACCTTTCTGA
TTGCGCCCTCCCTGCCCCCGGTGAATATCCCTTTATTCTCCAGCGCTGCACTCTGGGTCGCCATCCAACAAATATTGATT
GGTGTTGCTCTGGGCGTGACGATGCAATTCGCCTTTGCCGCCGTTCGGTTATCCGGAGAGGTGATTGGGTTACAAATGGG
GTTATCTTTCGCCACCTTCTTTGACCCTTCAGGTGGGCCAAACATGCCGGTATTATCCCGCTTGCTTAACATCCTGGTGA
CGCTGCTCTTCCTCTCTTTTGATGGTCACTTATGGCTCATTTCATTGTTAGCAGACAGTTTCCATACTTTACCCATTCAA
TTTGCCCCCCTTAATGGCAACGGTTTTCTCACGCTGGCCCAGTCAGGTTCGATGATCTTTATGAATGGGCTGATGCTGGC
TCTCCCCTTGATTACCCTGTTGTTAACCTTGAATATGGCCTTGGGGATGTTGAACCGGATGACGCCACAACTCTCTGTTT
TCGTTATTGGTTTCCCGTTAACACTGACCGTAGGTATTATCTCTTTGGGTTTGATCATGCCATTGTTAGCCCCTTTCACC
GAACACCTGTTTAGTGAATTCTTCGACCGCCTGGCCGAGGTATTAAGCGGCATGGCAAACTGA

Upstream 100 bases:

>100_bases
TCTTCACCACTATGGTGATTGCAGGCCCGTGGATGCTGAACTTGATCCTGGACTATATGCGCAATTTATTCACCAGCCTG
CCCACGTTGATTGGCTAGCC

Downstream 100 bases:

>100_bases
TAGCGAGAAAATGACGTTCATTGCATCACGATTATCAACGCGTTTACGCTGCGTGCCCAGCGGGTGACTATTTTTTGCTC
CGGAATAAGTGGGCCATTAT

Product: flagellar biosynthesis protein FliR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 260; Mature: 260

Protein sequence:

>260_residues
MLSFDTHQLSVWVSQYFWPLVRVLALIGTAPLLSEKQINKKVKIGLGVLITFLIAPSLPPVNIPLFSSAALWVAIQQILI
GVALGVTMQFAFAAVRLSGEVIGLQMGLSFATFFDPSGGPNMPVLSRLLNILVTLLFLSFDGHLWLISLLADSFHTLPIQ
FAPLNGNGFLTLAQSGSMIFMNGLMLALPLITLLLTLNMALGMLNRMTPQLSVFVIGFPLTLTVGIISLGLIMPLLAPFT
EHLFSEFFDRLAEVLSGMAN

Sequences:

>Translated_260_residues
MLSFDTHQLSVWVSQYFWPLVRVLALIGTAPLLSEKQINKKVKIGLGVLITFLIAPSLPPVNIPLFSSAALWVAIQQILI
GVALGVTMQFAFAAVRLSGEVIGLQMGLSFATFFDPSGGPNMPVLSRLLNILVTLLFLSFDGHLWLISLLADSFHTLPIQ
FAPLNGNGFLTLAQSGSMIFMNGLMLALPLITLLLTLNMALGMLNRMTPQLSVFVIGFPLTLTVGIISLGLIMPLLAPFT
EHLFSEFFDRLAEVLSGMAN
>Mature_260_residues
MLSFDTHQLSVWVSQYFWPLVRVLALIGTAPLLSEKQINKKVKIGLGVLITFLIAPSLPPVNIPLFSSAALWVAIQQILI
GVALGVTMQFAFAAVRLSGEVIGLQMGLSFATFFDPSGGPNMPVLSRLLNILVTLLFLSFDGHLWLISLLADSFHTLPIQ
FAPLNGNGFLTLAQSGSMIFMNGLMLALPLITLLLTLNMALGMLNRMTPQLSVFVIGFPLTLTVGIISLGLIMPLLAPFT
EHLFSEFFDRLAEVLSGMAN

Specific function: Role in flagellar biosynthesis [H]

COG id: COG1684

COG function: function code NU; Flagellar biosynthesis pathway, component FliR

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential). Bacterial flagellum basal body [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fliR/mopE/spaR family [H]

Homologues:

Organism=Escherichia coli, GI1788261, Length=258, Percent_Identity=67.0542635658915, Blast_Score=308, Evalue=2e-85,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006303
- InterPro:   IPR002010 [H]

Pfam domain/function: PF01311 Bac_export_1 [H]

EC number: NA

Molecular weight: Translated: 28211; Mature: 28211

Theoretical pI: Translated: 6.97; Mature: 6.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSFDTHQLSVWVSQYFWPLVRVLALIGTAPLLSEKQINKKVKIGLGVLITFLIAPSLPP
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCHHHHHHHHHHHHHHHCCCCCC
VNIPLFSSAALWVAIQQILIGVALGVTMQFAFAAVRLSGEVIGLQMGLSFATFFDPSGGP
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHCCHHHEEECCCCCC
NMPVLSRLLNILVTLLFLSFDGHLWLISLLADSFHTLPIQFAPLNGNGFLTLAQSGSMIF
CCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCEEEEEECCCEEEEEECCCCCHH
MNGLMLALPLITLLLTLNMALGMLNRMTPQLSVFVIGFPLTLTVGIISLGLIMPLLAPFT
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHH
EHLFSEFFDRLAEVLSGMAN
HHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLSFDTHQLSVWVSQYFWPLVRVLALIGTAPLLSEKQINKKVKIGLGVLITFLIAPSLPP
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCHHHHHHHHHHHHHHHCCCCCC
VNIPLFSSAALWVAIQQILIGVALGVTMQFAFAAVRLSGEVIGLQMGLSFATFFDPSGGP
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHCCHHHEEECCCCCC
NMPVLSRLLNILVTLLFLSFDGHLWLISLLADSFHTLPIQFAPLNGNGFLTLAQSGSMIF
CCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCEEEEEECCCEEEEEECCCCCHH
MNGLMLALPLITLLLTLNMALGMLNRMTPQLSVFVIGFPLTLTVGIISLGLIMPLLAPFT
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHH
EHLFSEFFDRLAEVLSGMAN
HHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8412685; 7934865 [H]