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The map label for this gene is fliI [H]

Identifier: 22126362

GI number: 22126362

Start: 2743187

End: 2744665

Strand: Direct

Name: fliI [H]

Synonym: y2479

Alternate gene names: 22126362

Gene position: 2743187-2744665 (Clockwise)

Preceding gene: 161484785

Following gene: 22126363

Centisome position: 59.62

GC content: 54.9

Gene sequence:

>1479_bases
ATGCCAGTCTGGCGACCCGTTGGCATGAACTGTGCCGTCTGGCCGCGCCGGGGGAACTGTGATGCCCCCCGCCTCAGCCG
CTGGCTTACCTCTTTAGATAAATTCGAAGAGCGTATCAGCCAAACGACAACAATCCGCCGTTATGGCCGCTTGACCCGCG
CCACCGGTTTAGTGCTGGAAGCCACTGGTCTGCAATTGCCGTTAGGGGCGACCTGTCTGATTGAGCGCCATAATGGCGGT
GAAGTGCAGGAAGTCGAAAGCGAAGTGGTTGGTTTTAACGGTCAGCATCTGTTTCTTATGCCTTTGGAAGATGTGGAAGG
TATCGTCCCCGGTGCCAGAGTGTATGCCCGAGTCACCACCAGCGGCACGTCTGCCAGTAAACAGTCAATTTCTAGTAAAC
AATCAATTCCCAGTAAACAATCATTCGCCAGTAAACAATTACCCCTTGGCCCCGAGTTATTGGGCCGGGTATTGGATGGC
AGTGCCAAACCGCTTGATGGCTTACCGGCACCTGAAACCGGTTATCGTGCACCACTGATTACACCACCGATAAACCCTTT
GCAACGCACCGCCATTGTCCAAGTCTTGGATGTGGGCGTGCGTACCATTAACGCCTTGTTGACGGTCGGGCGCGGCCAGC
GGATGGGGCTGTTTGCTGGCTCTGGGGTTGGCAAAAGCGTACTGCTCGGCATGATGGCCCGTTACACACAGGCTGACGTG
ATCGTGGTTGGGCTGATTGGTGAGCGTGGCCGTGAAGTCAAAGATTTTATCGAAAATATTCTCGGGGCTGAAGGCCGTGC
CCGTTCGGTGGTTATCGCCGCGCCAGCCGATGTGTCACCGTTGCTGCGTATGCAAGGTGCCGCCTATGCCACCCGTATTG
CCGAAGATTTCCGCGATCGTGGTCAGCATGTGTTGCTAATTATGGACTCCCTAACCCGCTATGCCATGGCGCAACGTGAA
ATCGCGCTGGCTATCGGCGAGCCTCCCGCGACCAAAGGTTATCCGCCCTCCGTCTTCGCCAAATTACCGGCACTGGTTGA
ACGGGCGGGTAACGGTGTTTCAGGCGGCGGCTCCATTACCGCATTTTATACCGTCCTCACCGAAGGTGATGATCAGCAAG
ATCCTATTGCTGACTCTGCGCGCGCCATCCTCGATGGCCATGTGGTGCTATCTCGCCGTTTGGCTGAATCCGGTCACTAT
CCGGCTATCGATATCGAAGCCTCTATCAGCCGTGCCATGACCTCATTAATCGATGATGACCATTACAGCCGGGTGCGCCA
GTTTAAACAACTGCTTGCCAGTTATCAGCGTAACCGCGATTTGATCAGTGTCGGGGCTTATGCTGCGGGCAGTGATCCCT
TATTGGACAAGGCGATTGCCCTGTACCCACAGATGGAGGCTTTCTTGCAGCAAGGCATGTTTGAGCGCAGCAGTTTTGAT
GATGCCTGCCAGCATTTGAAGGTTTTATTTCCAGGATAA

Upstream 100 bases:

>100_bases
CGGTTAGGTTCCACGCTGAGCTTGCACGGCTGGCGCTTATTGGGCGACAGCCAGATTCATGCTGGCGGCTGTAAAGTCAG
CGCGGAAGAAGGCGATTTGG

Downstream 100 bases:

>100_bases
GGGTTTCGTTTATTTCCCGGCTAAGTCGTTATTAAGGCTGAGCAGCCGGAAAAGATGACGCAAACCGCCGTGTCGCCCCT
GTAATCAATGAGGAATTCGA

Product: flagellum-specific ATP synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 492; Mature: 491

Protein sequence:

>492_residues
MPVWRPVGMNCAVWPRRGNCDAPRLSRWLTSLDKFEERISQTTTIRRYGRLTRATGLVLEATGLQLPLGATCLIERHNGG
EVQEVESEVVGFNGQHLFLMPLEDVEGIVPGARVYARVTTSGTSASKQSISSKQSIPSKQSFASKQLPLGPELLGRVLDG
SAKPLDGLPAPETGYRAPLITPPINPLQRTAIVQVLDVGVRTINALLTVGRGQRMGLFAGSGVGKSVLLGMMARYTQADV
IVVGLIGERGREVKDFIENILGAEGRARSVVIAAPADVSPLLRMQGAAYATRIAEDFRDRGQHVLLIMDSLTRYAMAQRE
IALAIGEPPATKGYPPSVFAKLPALVERAGNGVSGGGSITAFYTVLTEGDDQQDPIADSARAILDGHVVLSRRLAESGHY
PAIDIEASISRAMTSLIDDDHYSRVRQFKQLLASYQRNRDLISVGAYAAGSDPLLDKAIALYPQMEAFLQQGMFERSSFD
DACQHLKVLFPG

Sequences:

>Translated_492_residues
MPVWRPVGMNCAVWPRRGNCDAPRLSRWLTSLDKFEERISQTTTIRRYGRLTRATGLVLEATGLQLPLGATCLIERHNGG
EVQEVESEVVGFNGQHLFLMPLEDVEGIVPGARVYARVTTSGTSASKQSISSKQSIPSKQSFASKQLPLGPELLGRVLDG
SAKPLDGLPAPETGYRAPLITPPINPLQRTAIVQVLDVGVRTINALLTVGRGQRMGLFAGSGVGKSVLLGMMARYTQADV
IVVGLIGERGREVKDFIENILGAEGRARSVVIAAPADVSPLLRMQGAAYATRIAEDFRDRGQHVLLIMDSLTRYAMAQRE
IALAIGEPPATKGYPPSVFAKLPALVERAGNGVSGGGSITAFYTVLTEGDDQQDPIADSARAILDGHVVLSRRLAESGHY
PAIDIEASISRAMTSLIDDDHYSRVRQFKQLLASYQRNRDLISVGAYAAGSDPLLDKAIALYPQMEAFLQQGMFERSSFD
DACQHLKVLFPG
>Mature_491_residues
PVWRPVGMNCAVWPRRGNCDAPRLSRWLTSLDKFEERISQTTTIRRYGRLTRATGLVLEATGLQLPLGATCLIERHNGGE
VQEVESEVVGFNGQHLFLMPLEDVEGIVPGARVYARVTTSGTSASKQSISSKQSIPSKQSFASKQLPLGPELLGRVLDGS
AKPLDGLPAPETGYRAPLITPPINPLQRTAIVQVLDVGVRTINALLTVGRGQRMGLFAGSGVGKSVLLGMMARYTQADVI
VVGLIGERGREVKDFIENILGAEGRARSVVIAAPADVSPLLRMQGAAYATRIAEDFRDRGQHVLLIMDSLTRYAMAQREI
ALAIGEPPATKGYPPSVFAKLPALVERAGNGVSGGGSITAFYTVLTEGDDQQDPIADSARAILDGHVVLSRRLAESGHYP
AIDIEASISRAMTSLIDDDHYSRVRQFKQLLASYQRNRDLISVGAYAAGSDPLLDKAIALYPQMEAFLQQGMFERSSFDD
ACQHLKVLFPG

Specific function: Probable catalytic subunit of a protein translocase for flagellum-specific export, or a proton translocase involved in local circuits at the flagellum. May be involved in a specialized protein export pathway that proceeds without signal peptide cleavage [

COG id: COG1157

COG function: function code NU; Flagellar biosynthesis/type III secretory pathway ATPase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family [H]

Homologues:

Organism=Homo sapiens, GI32189394, Length=316, Percent_Identity=29.4303797468354, Blast_Score=135, Evalue=8e-32,
Organism=Homo sapiens, GI50345984, Length=374, Percent_Identity=26.2032085561497, Blast_Score=119, Evalue=9e-27,
Organism=Homo sapiens, GI4757810, Length=374, Percent_Identity=26.2032085561497, Blast_Score=119, Evalue=9e-27,
Organism=Homo sapiens, GI19913428, Length=415, Percent_Identity=27.4698795180723, Blast_Score=113, Evalue=4e-25,
Organism=Homo sapiens, GI19913426, Length=413, Percent_Identity=27.6029055690073, Blast_Score=111, Evalue=2e-24,
Organism=Homo sapiens, GI19913424, Length=319, Percent_Identity=28.2131661442006, Blast_Score=109, Evalue=7e-24,
Organism=Escherichia coli, GI1788251, Length=459, Percent_Identity=80.1742919389978, Blast_Score=714, Evalue=0.0,
Organism=Escherichia coli, GI1790170, Length=343, Percent_Identity=29.7376093294461, Blast_Score=141, Evalue=9e-35,
Organism=Escherichia coli, GI1790172, Length=284, Percent_Identity=28.169014084507, Blast_Score=101, Evalue=9e-23,
Organism=Escherichia coli, GI1790217, Length=241, Percent_Identity=26.5560165975104, Blast_Score=62, Evalue=1e-10,
Organism=Caenorhabditis elegans, GI25144756, Length=312, Percent_Identity=29.1666666666667, Blast_Score=125, Evalue=4e-29,
Organism=Caenorhabditis elegans, GI17570191, Length=374, Percent_Identity=28.6096256684492, Blast_Score=114, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI71988080, Length=351, Percent_Identity=27.0655270655271, Blast_Score=113, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI71988063, Length=353, Percent_Identity=28.0453257790368, Blast_Score=112, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI17510931, Length=354, Percent_Identity=25.9887005649718, Blast_Score=108, Evalue=7e-24,
Organism=Caenorhabditis elegans, GI17565854, Length=324, Percent_Identity=28.0864197530864, Blast_Score=104, Evalue=9e-23,
Organism=Caenorhabditis elegans, GI71988074, Length=341, Percent_Identity=26.6862170087977, Blast_Score=100, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6322581, Length=309, Percent_Identity=29.7734627831715, Blast_Score=138, Evalue=2e-33,
Organism=Saccharomyces cerevisiae, GI6319370, Length=346, Percent_Identity=27.1676300578035, Blast_Score=122, Evalue=2e-28,
Organism=Saccharomyces cerevisiae, GI6319603, Length=380, Percent_Identity=28.6842105263158, Blast_Score=117, Evalue=4e-27,
Organism=Saccharomyces cerevisiae, GI6320016, Length=280, Percent_Identity=28.9285714285714, Blast_Score=95, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24638766, Length=311, Percent_Identity=29.2604501607717, Blast_Score=130, Evalue=2e-30,
Organism=Drosophila melanogaster, GI24658560, Length=377, Percent_Identity=27.8514588859416, Blast_Score=121, Evalue=1e-27,
Organism=Drosophila melanogaster, GI28574560, Length=341, Percent_Identity=28.1524926686217, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI281361666, Length=419, Percent_Identity=26.9689737470167, Blast_Score=113, Evalue=4e-25,
Organism=Drosophila melanogaster, GI24646341, Length=419, Percent_Identity=26.9689737470167, Blast_Score=113, Evalue=4e-25,
Organism=Drosophila melanogaster, GI17136796, Length=419, Percent_Identity=26.9689737470167, Blast_Score=113, Evalue=4e-25,
Organism=Drosophila melanogaster, GI20129479, Length=314, Percent_Identity=28.343949044586, Blast_Score=106, Evalue=4e-23,
Organism=Drosophila melanogaster, GI24583988, Length=318, Percent_Identity=27.9874213836478, Blast_Score=105, Evalue=5e-23,
Organism=Drosophila melanogaster, GI24583986, Length=318, Percent_Identity=27.9874213836478, Blast_Score=105, Evalue=5e-23,
Organism=Drosophila melanogaster, GI24583984, Length=318, Percent_Identity=27.9874213836478, Blast_Score=105, Evalue=5e-23,
Organism=Drosophila melanogaster, GI24583992, Length=319, Percent_Identity=27.5862068965517, Blast_Score=104, Evalue=1e-22,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR003593
- InterPro:   IPR005714
- InterPro:   IPR020005 [H]

Pfam domain/function: PF00006 ATP-synt_ab [H]

EC number: =3.6.3.14 [H]

Molecular weight: Translated: 53189; Mature: 53058

Theoretical pI: Translated: 8.30; Mature: 8.30

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVWRPVGMNCAVWPRRGNCDAPRLSRWLTSLDKFEERISQTTTIRRYGRLTRATGLVLE
CCCCCCCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEE
ATGLQLPLGATCLIERHNGGEVQEVESEVVGFNGQHLFLMPLEDVEGIVPGARVYARVTT
ECCCCCCCCCEEEEEECCCCCHHHHHHHHCCCCCCEEEEEEHHHHCCCCCCCEEEEEEEC
SGTSASKQSISSKQSIPSKQSFASKQLPLGPELLGRVLDGSAKPLDGLPAPETGYRAPLI
CCCCHHHHHHHHHHCCCCHHHHHCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC
TPPINPLQRTAIVQVLDVGVRTINALLTVGRGQRMGLFAGSGVGKSVLLGMMARYTQADV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHCCCCE
IVVGLIGERGREVKDFIENILGAEGRARSVVIAAPADVSPLLRMQGAAYATRIAEDFRDR
EEEEECCCCCCHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHCCHHHHHHHHHHHHHC
GQHVLLIMDSLTRYAMAQREIALAIGEPPATKGYPPSVFAKLPALVERAGNGVSGGGSIT
CCEEEEEHHHHHHHHHHHHHEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCEE
AFYTVLTEGDDQQDPIADSARAILDGHVVLSRRLAESGHYPAIDIEASISRAMTSLIDDD
EEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHCCH
HYSRVRQFKQLLASYQRNRDLISVGAYAAGSDPLLDKAIALYPQMEAFLQQGMFERSSFD
HHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHH
DACQHLKVLFPG
HHHHHHEEECCC
>Mature Secondary Structure 
PVWRPVGMNCAVWPRRGNCDAPRLSRWLTSLDKFEERISQTTTIRRYGRLTRATGLVLE
CCCCCCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEE
ATGLQLPLGATCLIERHNGGEVQEVESEVVGFNGQHLFLMPLEDVEGIVPGARVYARVTT
ECCCCCCCCCEEEEEECCCCCHHHHHHHHCCCCCCEEEEEEHHHHCCCCCCCEEEEEEEC
SGTSASKQSISSKQSIPSKQSFASKQLPLGPELLGRVLDGSAKPLDGLPAPETGYRAPLI
CCCCHHHHHHHHHHCCCCHHHHHCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC
TPPINPLQRTAIVQVLDVGVRTINALLTVGRGQRMGLFAGSGVGKSVLLGMMARYTQADV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHCCCCE
IVVGLIGERGREVKDFIENILGAEGRARSVVIAAPADVSPLLRMQGAAYATRIAEDFRDR
EEEEECCCCCCHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHCCHHHHHHHHHHHHHC
GQHVLLIMDSLTRYAMAQREIALAIGEPPATKGYPPSVFAKLPALVERAGNGVSGGGSIT
CCEEEEEHHHHHHHHHHHHHEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCEE
AFYTVLTEGDDQQDPIADSARAILDGHVVLSRRLAESGHYPAIDIEASISRAMTSLIDDD
EEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHCCH
HYSRVRQFKQLLASYQRNRDLISVGAYAAGSDPLLDKAIALYPQMEAFLQQGMFERSSFD
HHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHH
DACQHLKVLFPG
HHHHHHEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]