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The map label for this gene is ydcR [H]

Identifier: 22126234

GI number: 22126234

Start: 2589041

End: 2590489

Strand: Reverse

Name: ydcR [H]

Synonym: y2350

Alternate gene names: 22126234

Gene position: 2590489-2589041 (Counterclockwise)

Preceding gene: 22126237

Following gene: 161484789

Centisome position: 56.31

GC content: 50.93

Gene sequence:

>1449_bases
TTGAATTTTATCTATAACAGATGGCTTATGACACGATATGAACAGCTAGCGCAGCAAATCAGAGCACAAATACAATCGAA
GGTCTGGCAAGCGGGCGATAAGCTCCCTTCGCTGCGAGAAAGTTGTAAACAATCAGGGCTAAGCCTGATGACCGTGGTGC
AATCGTATCAGTTGTTGGAAAGCCAGGGGTGGATCGTTGCCCGCCCACAATCGGGCTACTATGTGGCCTCACGGCCCACG
CAGTTACCGCAACCACAGCGGGGTAATAAGCTCCATCTGGATGAACAGGTTGATATCAATACCTTTATTTTTAATGTGTT
ACAGGCAGGGAAAGATCCGGCAATCATGCCGTTCGGTTCAGCATTTCCAGATCCGAGTTTATTGTTACAACCGCGTTTGT
CGCGGGCGTTGGCCAGCGTCGCTCGCAAGATCTCGCCACAAAGTTCTGTAACGAATTTGCCACCGGGTAATGAAAGTTTA
CGGCGCAATATTGCGCAACGTTATGCTGCCTGCGGGATGAATGTATCACCCGAGGAAATTGTGATTACGGCGGGGGCGAT
GGAGTCACTGAGCCTTAGCTTACAAGCCGTGACACAGCCCGGTGATTGGGTCGTTATTGAATCGCCCGCGTTTTATGGTG
CATTACAGGCGATTGAACGCCTACGACTTAAGGCTATTGCCATTACGACGGATCCCCAGCAAGGTGTGGATTTGGAGGCC
CTTGAGCAGGTTATCAGCCAGTATCCGATAAAAGCGTGCTGGTTAATGCCCCATTTTCAAAACCCAATGGGGGCCACCAT
GCCGTGGTCACAGAAACAGCGACTCGTCACCCTGCTACAGCAGAAGGCTATTTCACTGATTGAAGATGATGTATATGGCG
AACTGTATTTTGGTGCTGAACGCTTGCTACCGGCAAAAGCGCTTGACCAGCATCGGCAGATTTTACATTGCTCCTCTTTT
TCTAAATGCCTGGCGCCGGGGTTCCGTGTGGGGTGGGTGGCAGCAGGTGAACATGCTCAGCGTATTCAACATTTACAGTT
GATGAGCACCGTTTCGGCCAGCGTCCCGACCCAACTGGCGATTGCGGATTATCTGAGCCAAGGGGGATACGATACTCACC
TGCGCCGCTTGCGTCGGGTAATGGAACAGCGGATGAGCACGTTGCATCAGGCCGTTGTTGAACACTTCCCCAAAAACATC
AAAATCAGCCACCCCGCTGGCGGCTATTTCTTATGGTTAGAATTGGAGCCACCTTTTAATGCCAGTGAACTGTACCGACG
GGCACTGGAGCAGGGGGTTAGCATTGCTCCTGGGAGAATGTTCACCACAGGGAGTCAGTTTGATCATTGCTTTCGCCTTA
ATGCCTCCTTTGCCTGGTCAGAACAAAGCGCAAAAGCGATTCGTATTTTGGCGAAGTTAATCGGCCAATTGACGAACGAA
CGTCGATAG

Upstream 100 bases:

>100_bases
GCTATCCGGCAGATGGCGATGTATCGGGTGGTGAGTATTTCAGGGGAAACTTGGCAGGTAGTTAACCATAAGTTAAAGTG
GCTATAATAGTGAAAATTAA

Downstream 100 bases:

>100_bases
CCGTAGAGGCTATTAATGATCATTAATCAACATCAACATCAACATCAACATCAACATCTTCGATCTGTTGACCCAGATGG
CCTCTTAGAATCGGGGCTAC

Product: multi modular; transcriptional regulator; also ATP-binding component of a transport system

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 482; Mature: 482

Protein sequence:

>482_residues
MNFIYNRWLMTRYEQLAQQIRAQIQSKVWQAGDKLPSLRESCKQSGLSLMTVVQSYQLLESQGWIVARPQSGYYVASRPT
QLPQPQRGNKLHLDEQVDINTFIFNVLQAGKDPAIMPFGSAFPDPSLLLQPRLSRALASVARKISPQSSVTNLPPGNESL
RRNIAQRYAACGMNVSPEEIVITAGAMESLSLSLQAVTQPGDWVVIESPAFYGALQAIERLRLKAIAITTDPQQGVDLEA
LEQVISQYPIKACWLMPHFQNPMGATMPWSQKQRLVTLLQQKAISLIEDDVYGELYFGAERLLPAKALDQHRQILHCSSF
SKCLAPGFRVGWVAAGEHAQRIQHLQLMSTVSASVPTQLAIADYLSQGGYDTHLRRLRRVMEQRMSTLHQAVVEHFPKNI
KISHPAGGYFLWLELEPPFNASELYRRALEQGVSIAPGRMFTTGSQFDHCFRLNASFAWSEQSAKAIRILAKLIGQLTNE
RR

Sequences:

>Translated_482_residues
MNFIYNRWLMTRYEQLAQQIRAQIQSKVWQAGDKLPSLRESCKQSGLSLMTVVQSYQLLESQGWIVARPQSGYYVASRPT
QLPQPQRGNKLHLDEQVDINTFIFNVLQAGKDPAIMPFGSAFPDPSLLLQPRLSRALASVARKISPQSSVTNLPPGNESL
RRNIAQRYAACGMNVSPEEIVITAGAMESLSLSLQAVTQPGDWVVIESPAFYGALQAIERLRLKAIAITTDPQQGVDLEA
LEQVISQYPIKACWLMPHFQNPMGATMPWSQKQRLVTLLQQKAISLIEDDVYGELYFGAERLLPAKALDQHRQILHCSSF
SKCLAPGFRVGWVAAGEHAQRIQHLQLMSTVSASVPTQLAIADYLSQGGYDTHLRRLRRVMEQRMSTLHQAVVEHFPKNI
KISHPAGGYFLWLELEPPFNASELYRRALEQGVSIAPGRMFTTGSQFDHCFRLNASFAWSEQSAKAIRILAKLIGQLTNE
RR
>Mature_482_residues
MNFIYNRWLMTRYEQLAQQIRAQIQSKVWQAGDKLPSLRESCKQSGLSLMTVVQSYQLLESQGWIVARPQSGYYVASRPT
QLPQPQRGNKLHLDEQVDINTFIFNVLQAGKDPAIMPFGSAFPDPSLLLQPRLSRALASVARKISPQSSVTNLPPGNESL
RRNIAQRYAACGMNVSPEEIVITAGAMESLSLSLQAVTQPGDWVVIESPAFYGALQAIERLRLKAIAITTDPQQGVDLEA
LEQVISQYPIKACWLMPHFQNPMGATMPWSQKQRLVTLLQQKAISLIEDDVYGELYFGAERLLPAKALDQHRQILHCSSF
SKCLAPGFRVGWVAAGEHAQRIQHLQLMSTVSASVPTQLAIADYLSQGGYDTHLRRLRRVMEQRMSTLHQAVVEHFPKNI
KISHPAGGYFLWLELEPPFNASELYRRALEQGVSIAPGRMFTTGSQFDHCFRLNASFAWSEQSAKAIRILAKLIGQLTNE
RR

Specific function: Unknown

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=319, Percent_Identity=26.6457680250784, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI33469970, Length=319, Percent_Identity=26.6457680250784, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI4507369, Length=181, Percent_Identity=24.3093922651934, Blast_Score=77, Evalue=5e-14,
Organism=Escherichia coli, GI1787710, Length=465, Percent_Identity=56.7741935483871, Blast_Score=558, Evalue=1e-160,
Organism=Escherichia coli, GI1790797, Length=469, Percent_Identity=35.181236673774, Blast_Score=300, Evalue=1e-82,
Organism=Saccharomyces cerevisiae, GI6321000, Length=243, Percent_Identity=27.1604938271605, Blast_Score=84, Evalue=5e-17,
Organism=Drosophila melanogaster, GI21356535, Length=374, Percent_Identity=23.7967914438503, Blast_Score=86, Evalue=4e-17,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 54094; Mature: 54094

Theoretical pI: Translated: 9.51; Mature: 9.51

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFIYNRWLMTRYEQLAQQIRAQIQSKVWQAGDKLPSLRESCKQSGLSLMTVVQSYQLLE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHH
SQGWIVARPQSGYYVASRPTQLPQPQRGNKLHLDEQVDINTFIFNVLQAGKDPAIMPFGS
CCCCEEECCCCCEEEECCCCCCCCCCCCCEECCCCCCCHHHHHHHHHHCCCCCCCCCCCC
AFPDPSLLLQPRLSRALASVARKISPQSSVTNLPPGNESLRRNIAQRYAACGMNVSPEEI
CCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCE
VITAGAMESLSLSLQAVTQPGDWVVIESPAFYGALQAIERLRLKAIAITTDPQQGVDLEA
EEECCCHHHHHEEEEEECCCCCEEEECCCHHHHHHHHHHHHHHEEEEEECCCCCCCCHHH
LEQVISQYPIKACWLMPHFQNPMGATMPWSQKQRLVTLLQQKAISLIEDDVYGELYFGAE
HHHHHHHCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHH
RLLPAKALDQHRQILHCSSFSKCLAPGFRVGWVAAGEHAQRIQHLQLMSTVSASVPTQLA
HHCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHCCCHHHH
IADYLSQGGYDTHLRRLRRVMEQRMSTLHQAVVEHFPKNIKISHPAGGYFLWLELEPPFN
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCEEEEEEECCCCC
ASELYRRALEQGVSIAPGRMFTTGSQFDHCFRLNASFAWSEQSAKAIRILAKLIGQLTNE
HHHHHHHHHHCCCCCCCCCEEECCCCCCCEEEECCCEEECHHHHHHHHHHHHHHHHHHCC
RR
CC
>Mature Secondary Structure
MNFIYNRWLMTRYEQLAQQIRAQIQSKVWQAGDKLPSLRESCKQSGLSLMTVVQSYQLLE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHH
SQGWIVARPQSGYYVASRPTQLPQPQRGNKLHLDEQVDINTFIFNVLQAGKDPAIMPFGS
CCCCEEECCCCCEEEECCCCCCCCCCCCCEECCCCCCCHHHHHHHHHHCCCCCCCCCCCC
AFPDPSLLLQPRLSRALASVARKISPQSSVTNLPPGNESLRRNIAQRYAACGMNVSPEEI
CCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCE
VITAGAMESLSLSLQAVTQPGDWVVIESPAFYGALQAIERLRLKAIAITTDPQQGVDLEA
EEECCCHHHHHEEEEEECCCCCEEEECCCHHHHHHHHHHHHHHEEEEEECCCCCCCCHHH
LEQVISQYPIKACWLMPHFQNPMGATMPWSQKQRLVTLLQQKAISLIEDDVYGELYFGAE
HHHHHHHCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHH
RLLPAKALDQHRQILHCSSFSKCLAPGFRVGWVAAGEHAQRIQHLQLMSTVSASVPTQLA
HHCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHCCCHHHH
IADYLSQGGYDTHLRRLRRVMEQRMSTLHQAVVEHFPKNIKISHPAGGYFLWLELEPPFN
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCEEEEEEECCCCC
ASELYRRALEQGVSIAPGRMFTTGSQFDHCFRLNASFAWSEQSAKAIRILAKLIGQLTNE
HHHHHHHHHHCCCCCCCCCEEECCCCCCCEEEECCCEEECHHHHHHHHHHHHHHHHHHCC
RR
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]