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The map label for this gene is mtaD [H]

Identifier: 22126223

GI number: 22126223

Start: 2573605

End: 2575029

Strand: Reverse

Name: mtaD [H]

Synonym: y2338

Alternate gene names: 22126223

Gene position: 2575029-2573605 (Counterclockwise)

Preceding gene: 22126227

Following gene: 22126222

Centisome position: 55.97

GC content: 49.47

Gene sequence:

>1425_bases
TTGACGCAGCTGCGGGGCGCGTTTGACTCTGAACAAAAATATTGGGATATCGCTATGCCAGTTTATTTTACCAAGCGTGC
TTTTTTACCTGATGGATGGGCTGCAGACGTGCAAATTGCGGTAGATGAGCTGGGGGATATACAGCGTATCAGCACTGGCA
GTAGCAGCAGTGGTTGTCAGGTTTTATCCGGGCCAGTATTACCTGGTATGCCTAATCTGCACTCTCATGCTTTTCAGCGC
ATGATGTCGGGGCTGGCAGAAGTTGCCGGTGATCCACAAGATAGCTTTTGGACTTGGCGGGATCTCATGTATCGGTTGGT
GCAACAACTGACGCCGGAACAGGTTGGTGTTATTGCCCGGCAACTTTATATCGAAATGCTGAAAGGCGGATATACCCAAG
TTGCTGAATTTCACTATTTACATCATAGCCCTGATGGTTCCCCTTACAATGACATAGGGGAAATGACGGCCCAATTGAGT
CAGGCGGCACAAGACGCTGGGATCGGAATGACTTTATTGCCAGTGCTGTATAGCTACGCAGGATTTGGTGCTCAACCCGC
ACAGCAAGGCCAGAGCCGTTTTATTCAGGATACCGAGAGTTATCTCAGACAACAGCAGGTTATCCGTCGGCAGTTGGCTA
ATCAGCCTTTACAAAATCAGGGGCTATGTTTTCACTCATTACGTGCTGTTGAGTTAAGTCAAATGCAGCAGATTTTACAC
GTATCGGATAAACAGTTACCGGTACATATTCATATTGCTGAACAGCAGAAAGAAGTTAATGACTGCCTGGCATGGTGTGG
CCAGCGCCCAGTTGCCTGGCTATATGGTCACTTACCGGTCGATAGCCGCTGGTGCCTTGTCCACGCGACACATTTGGATA
CGTCAGAATTGGTTATGTTAGCCAATAGTCAGGCTGTTGCCGGGTTGTGTCCAACGACAGAGGCCAATTTGGGAGATGGT
ATTTTCCCCGGTGTTGACTATATACATCATCAGGGCCGTTGGGGGATAGGTTCTGATAGCCATGTTTCGCTGGATGTTGT
GGAGGAGCTACGTTGGTTGGAATATGGGCAACGCTTGCGTGATCAACGGCGTAACCGTTTGACCTGTGAGCGGCAACTCG
CCGTGGCGGATCTATTGTACAGCCAAGCATTAGCCGGAGGGCGTCAGGCTTGCGGGCGTCAAATTAGCCAGCTAGCCGTA
GGCTATCGTGCCGATTGGTTAGTACTCGATGGCGATGATCCTTATATTGCCGGGACAAGATCGGCATCTTTGTTGAATAG
ATGGTTATTTGCGGGGGGTAAATCGCAAATTCGAGATGTTTATGTGGCAGGCAAGGCGGTAATCGTGGATAGATATCATC
CATTGCAACAGCAAACTGCGCAAGCTTTTCTGGCTGTACTGAAAGCCTGCCAACAGGAGGTCTGA

Upstream 100 bases:

>100_bases
CTGCCACGGCGTTAACCTCGTCAAATAGAATATTTATATGCTAAGTCTACGGTTGAATTTAGCGTGTGTATATGTATATA
CAAGTAAGCGATTTAATTAA

Downstream 100 bases:

>100_bases
TGAGTTTTACCGTTTTTGATTTTGCCGGTCTGCCCGTCAGCCGCTGGCGAAATGGTGGCGGCGAAACCCGTGAAATTGCG
TGTTGGCCTGTCGGCGGTGA

Product: N-formimino-L-glutamate deiminase

Products: NA

Alternate protein names: MTA/SAH deaminase [H]

Number of amino acids: Translated: 474; Mature: 473

Protein sequence:

>474_residues
MTQLRGAFDSEQKYWDIAMPVYFTKRAFLPDGWAADVQIAVDELGDIQRISTGSSSSGCQVLSGPVLPGMPNLHSHAFQR
MMSGLAEVAGDPQDSFWTWRDLMYRLVQQLTPEQVGVIARQLYIEMLKGGYTQVAEFHYLHHSPDGSPYNDIGEMTAQLS
QAAQDAGIGMTLLPVLYSYAGFGAQPAQQGQSRFIQDTESYLRQQQVIRRQLANQPLQNQGLCFHSLRAVELSQMQQILH
VSDKQLPVHIHIAEQQKEVNDCLAWCGQRPVAWLYGHLPVDSRWCLVHATHLDTSELVMLANSQAVAGLCPTTEANLGDG
IFPGVDYIHHQGRWGIGSDSHVSLDVVEELRWLEYGQRLRDQRRNRLTCERQLAVADLLYSQALAGGRQACGRQISQLAV
GYRADWLVLDGDDPYIAGTRSASLLNRWLFAGGKSQIRDVYVAGKAVIVDRYHPLQQQTAQAFLAVLKACQQEV

Sequences:

>Translated_474_residues
MTQLRGAFDSEQKYWDIAMPVYFTKRAFLPDGWAADVQIAVDELGDIQRISTGSSSSGCQVLSGPVLPGMPNLHSHAFQR
MMSGLAEVAGDPQDSFWTWRDLMYRLVQQLTPEQVGVIARQLYIEMLKGGYTQVAEFHYLHHSPDGSPYNDIGEMTAQLS
QAAQDAGIGMTLLPVLYSYAGFGAQPAQQGQSRFIQDTESYLRQQQVIRRQLANQPLQNQGLCFHSLRAVELSQMQQILH
VSDKQLPVHIHIAEQQKEVNDCLAWCGQRPVAWLYGHLPVDSRWCLVHATHLDTSELVMLANSQAVAGLCPTTEANLGDG
IFPGVDYIHHQGRWGIGSDSHVSLDVVEELRWLEYGQRLRDQRRNRLTCERQLAVADLLYSQALAGGRQACGRQISQLAV
GYRADWLVLDGDDPYIAGTRSASLLNRWLFAGGKSQIRDVYVAGKAVIVDRYHPLQQQTAQAFLAVLKACQQEV
>Mature_473_residues
TQLRGAFDSEQKYWDIAMPVYFTKRAFLPDGWAADVQIAVDELGDIQRISTGSSSSGCQVLSGPVLPGMPNLHSHAFQRM
MSGLAEVAGDPQDSFWTWRDLMYRLVQQLTPEQVGVIARQLYIEMLKGGYTQVAEFHYLHHSPDGSPYNDIGEMTAQLSQ
AAQDAGIGMTLLPVLYSYAGFGAQPAQQGQSRFIQDTESYLRQQQVIRRQLANQPLQNQGLCFHSLRAVELSQMQQILHV
SDKQLPVHIHIAEQQKEVNDCLAWCGQRPVAWLYGHLPVDSRWCLVHATHLDTSELVMLANSQAVAGLCPTTEANLGDGI
FPGVDYIHHQGRWGIGSDSHVSLDVVEELRWLEYGQRLRDQRRNRLTCERQLAVADLLYSQALAGGRQACGRQISQLAVG
YRADWLVLDGDDPYIAGTRSASLLNRWLFAGGKSQIRDVYVAGKAVIVDRYHPLQQQTAQAFLAVLKACQQEV

Specific function: Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine [H]

COG id: COG0402

COG function: function code FR; Cytosine deaminase and related metal-dependent hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MTA/SAH deaminase family [H]

Homologues:

Organism=Caenorhabditis elegans, GI17540282, Length=432, Percent_Identity=30.3240740740741, Blast_Score=215, Evalue=4e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.4.28 [H]

Molecular weight: Translated: 52932; Mature: 52800

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQLRGAFDSEQKYWDIAMPVYFTKRAFLPDGWAADVQIAVDELGDIQRISTGSSSSGCQ
CCCCCCCCCCCCCEEEEECCHHHHHHHCCCCCCCCHHEEEHHHCCCHHHCCCCCCCCCCE
VLSGPVLPGMPNLHSHAFQRMMSGLAEVAGDPQDSFWTWRDLMYRLVQQLTPEQVGVIAR
EECCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHH
QLYIEMLKGGYTQVAEFHYLHHSPDGSPYNDIGEMTAQLSQAAQDAGIGMTLLPVLYSYA
HHHHHHHHCCHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
GFGAQPAQQGQSRFIQDTESYLRQQQVIRRQLANQPLQNQGLCFHSLRAVELSQMQQILH
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHH
VSDKQLPVHIHIAEQQKEVNDCLAWCGQRPVAWLYGHLPVDSRWCLVHATHLDTSELVML
CCCCCCEEEEEECHHHHHHHHHHHHHCCCCCCCEEECCCCCCCEEEEEEEECCHHHEEEE
ANSQAVAGLCPTTEANLGDGIFPGVDYIHHQGRWGIGSDSHVSLDVVEELRWLEYGQRLR
ECCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHH
DQRRNRLTCERQLAVADLLYSQALAGGRQACGRQISQLAVGYRADWLVLDGDDPYIAGTR
HHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCEEEECCCCCEEECCH
SASLLNRWLFAGGKSQIRDVYVAGKAVIVDRYHPLQQQTAQAFLAVLKACQQEV
HHHHHHHHHHCCCHHHHHHEEEECCEEEEECCCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TQLRGAFDSEQKYWDIAMPVYFTKRAFLPDGWAADVQIAVDELGDIQRISTGSSSSGCQ
CCCCCCCCCCCCEEEEECCHHHHHHHCCCCCCCCHHEEEHHHCCCHHHCCCCCCCCCCE
VLSGPVLPGMPNLHSHAFQRMMSGLAEVAGDPQDSFWTWRDLMYRLVQQLTPEQVGVIAR
EECCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHH
QLYIEMLKGGYTQVAEFHYLHHSPDGSPYNDIGEMTAQLSQAAQDAGIGMTLLPVLYSYA
HHHHHHHHCCHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
GFGAQPAQQGQSRFIQDTESYLRQQQVIRRQLANQPLQNQGLCFHSLRAVELSQMQQILH
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHH
VSDKQLPVHIHIAEQQKEVNDCLAWCGQRPVAWLYGHLPVDSRWCLVHATHLDTSELVML
CCCCCCEEEEEECHHHHHHHHHHHHHCCCCCCCEEECCCCCCCEEEEEEEECCHHHEEEE
ANSQAVAGLCPTTEANLGDGIFPGVDYIHHQGRWGIGSDSHVSLDVVEELRWLEYGQRLR
ECCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHH
DQRRNRLTCERQLAVADLLYSQALAGGRQACGRQISQLAVGYRADWLVLDGDDPYIAGTR
HHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCEEEECCCCCEEECCH
SASLLNRWLFAGGKSQIRDVYVAGKAVIVDRYHPLQQQTAQAFLAVLKACQQEV
HHHHHHHHHHCCCHHHHHHEEEECCEEEEECCCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA