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The map label for this gene is msrB [H]

Identifier: 22126052

GI number: 22126052

Start: 2391287

End: 2391757

Strand: Reverse

Name: msrB [H]

Synonym: y2164

Alternate gene names: 22126052

Gene position: 2391757-2391287 (Counterclockwise)

Preceding gene: 22126055

Following gene: 22126051

Centisome position: 51.99

GC content: 44.37

Gene sequence:

>471_bases
TTGTTATTATTAGACGTTGTTTTCGTTGACTTTATTCCCTGCCAGAGAACCGCAAAAATGGCCAAAGAACTGAACCCTAC
AGAAAATATTGAGAAACTGTCCGATATTCAGCGGTATGTCACCCAAGAACGTGGAACGGAAGCCCCCTTCACGGGCAAAT
TGTTGCACAATAAGCGTGATGGGGTGTACCAATGTCTGTGTTGTCACCAGCCGCTCTTTATCTCTGAATCAAAGTTTGAT
TCTGGCTGTGGTTGGCCAAGCTTCTATCAACCCATTGACGCTGATTCAATACGCTATATTGATGATTATTCTCATAATAT
GCATCGTATCGAAATTCGTTGTGGTAATTGTGATGCCCATTTGGGGCATGTATTCCCCGACGGACCGCAGCCTACGGGTG
AACGTTATTGCATAAATTCGGCGTCACTGAATTTCGTTGATGACCAAAATGGTGAGCAAACTGCAGGCTGA

Upstream 100 bases:

>100_bases
GTGATAATCGATAATATTTGCGATTTTTATCACATTTACGCCGTTGCCACCTCGATGGCATACAGTTTAGGACAATTTTA
ACTGCTTTGTTGTTAATTTT

Downstream 100 bases:

>100_bases
AGAGAAACATCGTAATTACATCTATGAAGAATCGATTCAGCTTATTATTCGTTTATCCGAGGATGCTCTGATGGAGCTTG
AAGACCTGATTTCAGTAATG

Product: methionine sulfoxide reductase B

Products: NA

Alternate protein names: Peptide-methionine (R)-S-oxide reductase [H]

Number of amino acids: Translated: 156; Mature: 156

Protein sequence:

>156_residues
MLLLDVVFVDFIPCQRTAKMAKELNPTENIEKLSDIQRYVTQERGTEAPFTGKLLHNKRDGVYQCLCCHQPLFISESKFD
SGCGWPSFYQPIDADSIRYIDDYSHNMHRIEIRCGNCDAHLGHVFPDGPQPTGERYCINSASLNFVDDQNGEQTAG

Sequences:

>Translated_156_residues
MLLLDVVFVDFIPCQRTAKMAKELNPTENIEKLSDIQRYVTQERGTEAPFTGKLLHNKRDGVYQCLCCHQPLFISESKFD
SGCGWPSFYQPIDADSIRYIDDYSHNMHRIEIRCGNCDAHLGHVFPDGPQPTGERYCINSASLNFVDDQNGEQTAG
>Mature_156_residues
MLLLDVVFVDFIPCQRTAKMAKELNPTENIEKLSDIQRYVTQERGTEAPFTGKLLHNKRDGVYQCLCCHQPLFISESKFD
SGCGWPSFYQPIDADSIRYIDDYSHNMHRIEIRCGNCDAHLGHVFPDGPQPTGERYCINSASLNFVDDQNGEQTAG

Specific function: Unknown

COG id: COG0229

COG function: function code O; Conserved domain frequently associated with peptide methionine sulfoxide reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the msrB Met sulfoxide reductase family [H]

Homologues:

Organism=Homo sapiens, GI301336164, Length=127, Percent_Identity=52.755905511811, Blast_Score=155, Evalue=1e-38,
Organism=Homo sapiens, GI301336162, Length=127, Percent_Identity=52.755905511811, Blast_Score=155, Evalue=1e-38,
Organism=Homo sapiens, GI73089054, Length=127, Percent_Identity=52.755905511811, Blast_Score=155, Evalue=1e-38,
Organism=Homo sapiens, GI37620216, Length=127, Percent_Identity=52.755905511811, Blast_Score=155, Evalue=2e-38,
Organism=Homo sapiens, GI117606353, Length=130, Percent_Identity=48.4615384615385, Blast_Score=125, Evalue=1e-29,
Organism=Homo sapiens, GI7706511, Length=108, Percent_Identity=37.037037037037, Blast_Score=65, Evalue=2e-11,
Organism=Escherichia coli, GI1788077, Length=137, Percent_Identity=69.3430656934307, Blast_Score=209, Evalue=9e-56,
Organism=Caenorhabditis elegans, GI17553450, Length=132, Percent_Identity=48.4848484848485, Blast_Score=123, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI115532676, Length=132, Percent_Identity=48.4848484848485, Blast_Score=123, Evalue=4e-29,
Organism=Saccharomyces cerevisiae, GI6319816, Length=140, Percent_Identity=40.7142857142857, Blast_Score=111, Evalue=4e-26,
Organism=Drosophila melanogaster, GI24645799, Length=125, Percent_Identity=52, Blast_Score=135, Evalue=8e-33,
Organism=Drosophila melanogaster, GI45553335, Length=125, Percent_Identity=52, Blast_Score=135, Evalue=8e-33,
Organism=Drosophila melanogaster, GI21356369, Length=125, Percent_Identity=52, Blast_Score=135, Evalue=8e-33,
Organism=Drosophila melanogaster, GI221378664, Length=124, Percent_Identity=51.6129032258064, Blast_Score=132, Evalue=1e-31,
Organism=Drosophila melanogaster, GI24645801, Length=136, Percent_Identity=47.7941176470588, Blast_Score=131, Evalue=2e-31,
Organism=Drosophila melanogaster, GI24645804, Length=136, Percent_Identity=47.7941176470588, Blast_Score=131, Evalue=2e-31,
Organism=Drosophila melanogaster, GI221378662, Length=131, Percent_Identity=48.8549618320611, Blast_Score=130, Evalue=4e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002579
- InterPro:   IPR011057 [H]

Pfam domain/function: PF01641 SelR [H]

EC number: =1.8.4.12 [H]

Molecular weight: Translated: 17706; Mature: 17706

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
7.1 %Cys+Met (Translated Protein)
5.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
7.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLLDVVFVDFIPCQRTAKMAKELNPTENIEKLSDIQRYVTQERGTEAPFTGKLLHNKRD
CEEEEEEHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCC
GVYQCLCCHQPLFISESKFDSGCGWPSFYQPIDADSIRYIDDYSHNMHRIEIRCGNCDAH
CCEEHHHHCCCEEEECCCCCCCCCCCHHCCCCCCCCEEEECCCCCCEEEEEEEECCCCCC
LGHVFPDGPQPTGERYCINSASLNFVDDQNGEQTAG
CCCCCCCCCCCCCCEEEECCCCEEEEECCCCCCCCC
>Mature Secondary Structure
MLLLDVVFVDFIPCQRTAKMAKELNPTENIEKLSDIQRYVTQERGTEAPFTGKLLHNKRD
CEEEEEEHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCC
GVYQCLCCHQPLFISESKFDSGCGWPSFYQPIDADSIRYIDDYSHNMHRIEIRCGNCDAH
CCEEHHHHCCCEEEECCCCCCCCCCCHHCCCCCCCCEEEECCCCCCEEEEEEEECCCCCC
LGHVFPDGPQPTGERYCINSASLNFVDDQNGEQTAG
CCCCCCCCCCCCCCEEEECCCCEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA