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The map label for this gene is dalD [H]

Identifier: 22125900

GI number: 22125900

Start: 2210709

End: 2212112

Strand: Reverse

Name: dalD [H]

Synonym: y2008

Alternate gene names: 22125900

Gene position: 2212112-2210709 (Counterclockwise)

Preceding gene: 22125902

Following gene: 22125896

Centisome position: 48.08

GC content: 50.21

Gene sequence:

>1404_bases
GTGGAGATTATTATGAATACTGACCTGAAATCACCCCCTGCTGTGTGGCTGCATATTGGTGCTGGCTCCTTCCACCGAGC
CCATCAGGCTTGGTATTTACACCGTTTGTTAGCCTCAGGCGATGACCGTTGGACTATCGCTTTGGCCAATATTCGTGATG
ACGCCATCCCACTACTGGACACATTGCGGGCGCAACACGGTGAATATGTCTTGGAAACGGTCACACCAAGCGGTGAACGC
CAGTATGAAAAGATAACATCACTGCGCAATATCATTCCTTGGGATAAAGCGCTAGATCATCTGGTAGCGCAAGGGAGTAA
ACCCGAAACTCGCGTGATCTCTTTCACCGTAACGGAGGGGGGCTACTATTTAGATAATCAATTTAATCTGCAACAGGACA
ATAGCGATATTCAGGCCGATCTTAGAGGAGATTGCCGCACGATTTACGGGGCAATTAGCCGTATCTTGCAACAACGGCAA
CAGGATAAGAGTGGCCCGGTCACTCTACTGAACTGCGATAACTTGCGTCACAACGGTGAACGATTCCGCCATGGCTTATT
AGAGTTTCTTGCTCTACGAGGTCAACAAAGCCTATTAAACTGGGTGACAAGCCAGACCCGCAGCCCGAATACCATGGTTG
ATCGTATCACCCCGCGCCCATCAGCCGATATCGCGCAGCGGGTGTTGGAAAAAACCGGTATCGTAGATAACGCTCCGGTG
ATGGGGGAATCATTTATTCAATGGGTTATTGAGGATGATTTTATTGCTGGCCGCCCGGCACTGGAGAACGTTGGGGCGGA
AATGGTCACCTCGGTTTTGCCTTATGAAGAAGCCAAAATCCGCATTCTGAACGCCAGCCACAGTTGTATTGCTTGGGCGG
GCAGCTTGATTGGGCAATGTTATATTCATGAAAGTACCCAAACCGACGCTATCCGCCAGATGGCTTATGACTATGTCACG
CAAGATGTCATTCCCTCCCTGACGCCCAGCCCACTTGATTTAGCCCATTACCGCGATGTGGTACTGGAACGTTTCAGTAA
TCCGTATATTCGCGATACGAACCAGCGTGTCGCCGCCGATGGATTTTCCAAAATCCCCGGATTTATCACTCCCACGCTGA
TCGAGTGTTACCAACGTGGCGGAGTGCCTACCGCTACCGCAATGTTGCCCGCATTATTCTTCGTATTTATGGAAAGTTGG
CACCAAGGCACTCTGCCGTATGAATATCAGGATGGTATTCTGGACCCAGCAGCCGTCCATGCCATGTTTCAGTCTTCTGA
CCCTGCAGGCTTATTTGCCCGTGATAGCGCCCTTTTCGGGCCGCTGGCCAATGATGATCAGTTCGAACAGTTATTACGCC
AGTCCATAAATCGTGTCTCTGCTTGGGTTAGCACTAACCGTTAA

Upstream 100 bases:

>100_bases
GCTCAATTTGAGGGCAAAAGTTACATTAACCTACACGAAAGGGCAAATGCCCAAATATTGAATTTATGCCCAAACAATAA
CTGTAGCACCTTCTGTAATT

Downstream 100 bases:

>100_bases
TCCCTGAGGAGGGGCTTGGGGGGGCGGCGCGTTTAGGGGGCGGGGGATCTCCGGTGATAAATGATCGTCAGTAATTAATG
ATCAGCCGTAATTAACGATC

Product: D-arabinitol dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 467; Mature: 467

Protein sequence:

>467_residues
MEIIMNTDLKSPPAVWLHIGAGSFHRAHQAWYLHRLLASGDDRWTIALANIRDDAIPLLDTLRAQHGEYVLETVTPSGER
QYEKITSLRNIIPWDKALDHLVAQGSKPETRVISFTVTEGGYYLDNQFNLQQDNSDIQADLRGDCRTIYGAISRILQQRQ
QDKSGPVTLLNCDNLRHNGERFRHGLLEFLALRGQQSLLNWVTSQTRSPNTMVDRITPRPSADIAQRVLEKTGIVDNAPV
MGESFIQWVIEDDFIAGRPALENVGAEMVTSVLPYEEAKIRILNASHSCIAWAGSLIGQCYIHESTQTDAIRQMAYDYVT
QDVIPSLTPSPLDLAHYRDVVLERFSNPYIRDTNQRVAADGFSKIPGFITPTLIECYQRGGVPTATAMLPALFFVFMESW
HQGTLPYEYQDGILDPAAVHAMFQSSDPAGLFARDSALFGPLANDDQFEQLLRQSINRVSAWVSTNR

Sequences:

>Translated_467_residues
MEIIMNTDLKSPPAVWLHIGAGSFHRAHQAWYLHRLLASGDDRWTIALANIRDDAIPLLDTLRAQHGEYVLETVTPSGER
QYEKITSLRNIIPWDKALDHLVAQGSKPETRVISFTVTEGGYYLDNQFNLQQDNSDIQADLRGDCRTIYGAISRILQQRQ
QDKSGPVTLLNCDNLRHNGERFRHGLLEFLALRGQQSLLNWVTSQTRSPNTMVDRITPRPSADIAQRVLEKTGIVDNAPV
MGESFIQWVIEDDFIAGRPALENVGAEMVTSVLPYEEAKIRILNASHSCIAWAGSLIGQCYIHESTQTDAIRQMAYDYVT
QDVIPSLTPSPLDLAHYRDVVLERFSNPYIRDTNQRVAADGFSKIPGFITPTLIECYQRGGVPTATAMLPALFFVFMESW
HQGTLPYEYQDGILDPAAVHAMFQSSDPAGLFARDSALFGPLANDDQFEQLLRQSINRVSAWVSTNR
>Mature_467_residues
MEIIMNTDLKSPPAVWLHIGAGSFHRAHQAWYLHRLLASGDDRWTIALANIRDDAIPLLDTLRAQHGEYVLETVTPSGER
QYEKITSLRNIIPWDKALDHLVAQGSKPETRVISFTVTEGGYYLDNQFNLQQDNSDIQADLRGDCRTIYGAISRILQQRQ
QDKSGPVTLLNCDNLRHNGERFRHGLLEFLALRGQQSLLNWVTSQTRSPNTMVDRITPRPSADIAQRVLEKTGIVDNAPV
MGESFIQWVIEDDFIAGRPALENVGAEMVTSVLPYEEAKIRILNASHSCIAWAGSLIGQCYIHESTQTDAIRQMAYDYVT
QDVIPSLTPSPLDLAHYRDVVLERFSNPYIRDTNQRVAADGFSKIPGFITPTLIECYQRGGVPTATAMLPALFFVFMESW
HQGTLPYEYQDGILDPAAVHAMFQSSDPAGLFARDSALFGPLANDDQFEQLLRQSINRVSAWVSTNR

Specific function: Hexuronate conversion to KDG. [C]

COG id: COG0246

COG function: function code G; Mannitol-1-phosphate/altronate dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mannitol dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1790779, Length=374, Percent_Identity=34.4919786096257, Blast_Score=206, Evalue=3e-54,
Organism=Escherichia coli, GI1788497, Length=356, Percent_Identity=33.1460674157303, Blast_Score=191, Evalue=1e-49,
Organism=Escherichia coli, GI1787823, Length=360, Percent_Identity=32.5, Blast_Score=184, Evalue=1e-47,
Organism=Escherichia coli, GI48994885, Length=414, Percent_Identity=22.2222222222222, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI1790028, Length=365, Percent_Identity=23.2876712328767, Blast_Score=70, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6324401, Length=456, Percent_Identity=32.6754385964912, Blast_Score=224, Evalue=2e-59,
Organism=Saccharomyces cerevisiae, GI6320765, Length=456, Percent_Identity=32.6754385964912, Blast_Score=224, Evalue=2e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR013328
- InterPro:   IPR000669
- InterPro:   IPR013118
- InterPro:   IPR013131
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01232 Mannitol_dh; PF08125 Mannitol_dh_C [H]

EC number: =1.1.1.11 [H]

Molecular weight: Translated: 52472; Mature: 52472

Theoretical pI: Translated: 5.28; Mature: 5.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEIIMNTDLKSPPAVWLHIGAGSFHRAHQAWYLHRLLASGDDRWTIALANIRDDAIPLLD
CEEEECCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHH
TLRAQHGEYVLETVTPSGERQYEKITSLRNIIPWDKALDHLVAQGSKPETRVISFTVTEG
HHHHHCCCEEEEECCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCEEEEEEEECC
GYYLDNQFNLQQDNSDIQADLRGDCRTIYGAISRILQQRQQDKSGPVTLLNCDNLRHNGE
CEEECCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCHH
RFRHGLLEFLALRGQQSLLNWVTSQTRSPNTMVDRITPRPSADIAQRVLEKTGIVDNAPV
HHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCHHHCCCCCCCHHHHHHHHHHHCCCCCCCC
MGESFIQWVIEDDFIAGRPALENVGAEMVTSVLPYEEAKIRILNASHSCIAWAGSLIGQC
CHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHEE
YIHESTQTDAIRQMAYDYVTQDVIPSLTPSPLDLAHYRDVVLERFSNPYIRDTNQRVAAD
EEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCEECCCCHHHHC
GFSKIPGFITPTLIECYQRGGVPTATAMLPALFFVFMESWHQGTLPYEYQDGILDPAAVH
CHHHCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHH
AMFQSSDPAGLFARDSALFGPLANDDQFEQLLRQSINRVSAWVSTNR
HHHCCCCCCCEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MEIIMNTDLKSPPAVWLHIGAGSFHRAHQAWYLHRLLASGDDRWTIALANIRDDAIPLLD
CEEEECCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHH
TLRAQHGEYVLETVTPSGERQYEKITSLRNIIPWDKALDHLVAQGSKPETRVISFTVTEG
HHHHHCCCEEEEECCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCEEEEEEEECC
GYYLDNQFNLQQDNSDIQADLRGDCRTIYGAISRILQQRQQDKSGPVTLLNCDNLRHNGE
CEEECCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCHH
RFRHGLLEFLALRGQQSLLNWVTSQTRSPNTMVDRITPRPSADIAQRVLEKTGIVDNAPV
HHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCHHHCCCCCCCHHHHHHHHHHHCCCCCCCC
MGESFIQWVIEDDFIAGRPALENVGAEMVTSVLPYEEAKIRILNASHSCIAWAGSLIGQC
CHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHEE
YIHESTQTDAIRQMAYDYVTQDVIPSLTPSPLDLAHYRDVVLERFSNPYIRDTNQRVAAD
EEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCEECCCCHHHHC
GFSKIPGFITPTLIECYQRGGVPTATAMLPALFFVFMESWHQGTLPYEYQDGILDPAAVH
CHHHCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHH
AMFQSSDPAGLFARDSALFGPLANDDQFEQLLRQSINRVSAWVSTNR
HHHCCCCCCCEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430 [H]