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The map label for this gene is sufA [H]

Identifier: 22125826

GI number: 22125826

Start: 2132475

End: 2132873

Strand: Direct

Name: sufA [H]

Synonym: y1934

Alternate gene names: 22125826

Gene position: 2132475-2132873 (Clockwise)

Preceding gene: 22125825

Following gene: 22125827

Centisome position: 46.35

GC content: 47.62

Gene sequence:

>399_bases
GTGATAGAGAAACATAAGGTAGAGCATATGCAACAAGAATCAGTTGGGACATTTTCTCTCGACGATAATGACTGGCAAGG
CGTGACGATTACGGACAGTGCCGCTGCGCAAATTACGCGGCTTATGCAACAAGACCCACAAATAAAAGGGTTACAGCTCG
GCGTCAAACAGTCCGGTTGTGCCGGTTTTGCCTATGTTATGGATATGGCTAAAGAGCCTGCCAGCGATGATCTGGTTTTT
GAACAGGGTAGCGCCAGGCTTTACGTGCCATTAAAAGCGATGCCGTTTATCGACGGGACCGAGGTGGATTATGTCCGCGA
AGGGCTAAACCAGATTTTTAAATTTAATAATCCTAAAGCTCAGCATTCCTGCGGGTGTGGCGAGAGTTTTGGCGTTTGA

Upstream 100 bases:

>100_bases
TGAATAATCTGTGTTGATCCATCAATAATCAGCCAGCAAATTTTCAACCTGAAAACGTTTAACCTAATAACTTTTAGCCG
GAAAAGTAACAACTCATCGG

Downstream 100 bases:

>100_bases
GTGATGCAAACTAAATGACACGAAGCAATGTAGAAATTCCAGATGATGTGCAGGCTTGGGTCAGTGATGGTCGGTATAAA
GAGGGCTTTTTTACACACTT

Product: iron-sulfur cluster assembly scaffold protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 132; Mature: 132

Protein sequence:

>132_residues
MIEKHKVEHMQQESVGTFSLDDNDWQGVTITDSAAAQITRLMQQDPQIKGLQLGVKQSGCAGFAYVMDMAKEPASDDLVF
EQGSARLYVPLKAMPFIDGTEVDYVREGLNQIFKFNNPKAQHSCGCGESFGV

Sequences:

>Translated_132_residues
MIEKHKVEHMQQESVGTFSLDDNDWQGVTITDSAAAQITRLMQQDPQIKGLQLGVKQSGCAGFAYVMDMAKEPASDDLVF
EQGSARLYVPLKAMPFIDGTEVDYVREGLNQIFKFNNPKAQHSCGCGESFGV
>Mature_132_residues
MIEKHKVEHMQQESVGTFSLDDNDWQGVTITDSAAAQITRLMQQDPQIKGLQLGVKQSGCAGFAYVMDMAKEPASDDLVF
EQGSARLYVPLKAMPFIDGTEVDYVREGLNQIFKFNNPKAQHSCGCGESFGV

Specific function: Unknown

COG id: COG0316

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hesB/iscA family [H]

Homologues:

Organism=Homo sapiens, GI52426768, Length=106, Percent_Identity=36.7924528301887, Blast_Score=86, Evalue=6e-18,
Organism=Homo sapiens, GI160420328, Length=106, Percent_Identity=36.7924528301887, Blast_Score=74, Evalue=4e-14,
Organism=Escherichia coli, GI1787974, Length=117, Percent_Identity=64.957264957265, Blast_Score=167, Evalue=2e-43,
Organism=Escherichia coli, GI1788877, Length=105, Percent_Identity=46.6666666666667, Blast_Score=113, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI25146411, Length=106, Percent_Identity=35.8490566037736, Blast_Score=82, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI193209025, Length=106, Percent_Identity=35.8490566037736, Blast_Score=82, Evalue=6e-17,
Organism=Saccharomyces cerevisiae, GI6323001, Length=105, Percent_Identity=33.3333333333333, Blast_Score=72, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24642263, Length=106, Percent_Identity=37.7358490566038, Blast_Score=86, Evalue=9e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000361
- InterPro:   IPR016092
- InterPro:   IPR017870
- InterPro:   IPR011298 [H]

Pfam domain/function: PF01521 Fe-S_biosyn [H]

EC number: NA

Molecular weight: Translated: 14563; Mature: 14563

Theoretical pI: Translated: 4.55; Mature: 4.55

Prosite motif: PS01152 HESB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
6.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIEKHKVEHMQQESVGTFSLDDNDWQGVTITDSAAAQITRLMQQDPQIKGLQLGVKQSGC
CCCCHHHHHHHHHCCCEEEECCCCCCCEEEECHHHHHHHHHHHCCCCCCCEEECCCCCCC
AGFAYVMDMAKEPASDDLVFEQGSARLYVPLKAMPFIDGTEVDYVREGLNQIFKFNNPKA
HHHHHHHHHHCCCCCCCEEEECCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCCC
QHSCGCGESFGV
CCCCCCCCCCCC
>Mature Secondary Structure
MIEKHKVEHMQQESVGTFSLDDNDWQGVTITDSAAAQITRLMQQDPQIKGLQLGVKQSGC
CCCCHHHHHHHHHCCCEEEECCCCCCCEEEECHHHHHHHHHHHCCCCCCCEEECCCCCCC
AGFAYVMDMAKEPASDDLVFEQGSARLYVPLKAMPFIDGTEVDYVREGLNQIFKFNNPKA
HHHHHHHHHHCCCCCCCEEEECCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCCC
QHSCGCGESFGV
CCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 10322040 [H]