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The map label for this gene is arnT

Identifier: 22125814

GI number: 22125814

Start: 2115288

End: 2116952

Strand: Direct

Name: arnT

Synonym: y1921

Alternate gene names: 22125814

Gene position: 2115288-2116952 (Clockwise)

Preceding gene: 22125813

Following gene: 22125815

Centisome position: 45.98

GC content: 45.11

Gene sequence:

>1665_bases
ATGAAATTATTAAAAGACAGTGGCGCAGCATTATTGGCGCTATTTTTTGTATTGGTTTATTTGTTACCGGTGAATAGCCG
TTTGTTATGGCAACCCGATGAAACTCGCTATGCTGAAATTAGTCGTGAAATGCTGCAGCGTGGCGACTGGGTCGTGCCGT
ATTTCATGGATATACGTTATTTTGAAAAACCGGTCGCCGGGTATTGGTTTAATAACATTAGCCAATGGATCTTTGGTGAC
AGTAATTTTGCAGTGAGATTTGGCTCTATTTTTAGCACGGCATTGAGTGCCGTATTAGTTTATTGGCTGGCAACCTTATT
ATGGCGTAATCGGTCAACCTCGGTACTGGCTACATTAATTTATCTTTCCTTTTTATTGGTGTTTGGCATTGGTACCTATG
CAGTGCTGGACCCCATGATTTCTCTGTGGTTGACAGCGGCGATGGTGAGTTTTTATCTCACGCTAAAAGCCGAAAATTGG
CAACAGAAAGTCGGCGCATATGCATTACTTGGGGTTGCTTGCGGTATGGGGTTTATGACCAAAGGCTTTCTGGCATTAGC
GGTCCCGGTGATTGCGGTATTACCCATTGTCATCCAGCAAAAAAGGATAAAAGACCTTGTTGTTTTTGGTCCGATAGCAA
TTGTGTGCGCGGTATTATTAAGTTTACCGTGGGCTTTGGCGATCGCCCAACGAGAACCTGATTTCTGGAACTATTTCTTT
TGGGTTGAACATATTCAGCGCTTTGCGGAAGCGAGTGCTCAACATAAATCTCCCATTTGGTATTACCTACCCATTTTATG
TATTGGTGTCCTGCCTTGGCTAGGGCTATTACCTGGAGCCTTATTTAAAGGTTGGCGTGAGCGGGCAACAAAACCAGAAT
TATTCTTTTTACTCAGTTGGGTGGTTATGCCACTCCTATTTTTTAGCGTAGCAAAAGGGAAGCTACCGACTTATATTTTG
CCCTGTATGGCACCTCTATCCTTGCTAATGGCGGCATATGCGACGGATTGCGCTAATAATATACGTATGCGGGCATTGAA
AATAAACGGTGTAATAAATCTACTCTTCGGGGTTGCCTGTGCGTTAGTCATCGTCGTTATTGGCTTGGGGTTAGTGAAGG
ATATCGTGGCTTATGGGCCGCAAGAGAATCAGAAAGTTTGGTTAGGTGTGTTGGCATTTGCTGGTTGGGGAGTCACTGGG
TTTATTACCTTACGCAATAACGCCCGAAACTGGCGCTGGGCAGCAGCTTGCCCACTGTTATTCATTTTGTTAGTGGGTTA
CCTAATTCCACAACAAGTGGTGGACTCAAAGCAACCGCAAAACTTTATCAAAAATAATTTTAGTGAACTCAGCTCCAGCC
GCTATGTGCTGACCGACAGCGTTGGTGTTGCCGCTGGGCTGGCATGGGAGCTAAAACGCAGTGATATACTGATGTTCAGT
GAAAAAGGTGAGCTAACCTATGGTTTGGCCTACCCAGACAGTCAGGATAATTATATCAGTAATGACGATTTCCCCACATG
GCTTGCGCAGGCGAGAAAAGAAGGCGACGTCTCATTGGTCGTGCAATTAGCCAAAAATGAAGCACTCCCGGCCCATCTGC
CGCCAGCGGATAAGGTGAATTTAATGAATCGACTCGCCCTGTTGTGGTACCAGAAAACACCATGA

Upstream 100 bases:

>100_bases
CGTCAGATTTACAATTACTGCCTGTGGGCAAAGTAATACGCGCTGCATTTCCTGGCCGGGAAGGTTGGTTGGGTTGTCAA
TCAGACATAAAGGATGCTGA

Downstream 100 bases:

>100_bases
ACAGCTACCTACTCTTGCTGATGGTCAGTCTATTAACCTGTATTGGGCAATTATGTCAAAAACAGGCTGCGCAGTGTTGG
GAGCAACCGCAGGCCCGGCG

Product: 4-amino-4-deoxy-L-arabinose transferase

Products: NA

Alternate protein names: 4-amino-4-deoxy-L-arabinose lipid A transferase; Lipid IV(A) 4-amino-4-deoxy-L-arabinosyltransferase; Undecaprenyl phosphate-alpha-L-Ara4N transferase

Number of amino acids: Translated: 554; Mature: 554

Protein sequence:

>554_residues
MKLLKDSGAALLALFFVLVYLLPVNSRLLWQPDETRYAEISREMLQRGDWVVPYFMDIRYFEKPVAGYWFNNISQWIFGD
SNFAVRFGSIFSTALSAVLVYWLATLLWRNRSTSVLATLIYLSFLLVFGIGTYAVLDPMISLWLTAAMVSFYLTLKAENW
QQKVGAYALLGVACGMGFMTKGFLALAVPVIAVLPIVIQQKRIKDLVVFGPIAIVCAVLLSLPWALAIAQREPDFWNYFF
WVEHIQRFAEASAQHKSPIWYYLPILCIGVLPWLGLLPGALFKGWRERATKPELFFLLSWVVMPLLFFSVAKGKLPTYIL
PCMAPLSLLMAAYATDCANNIRMRALKINGVINLLFGVACALVIVVIGLGLVKDIVAYGPQENQKVWLGVLAFAGWGVTG
FITLRNNARNWRWAAACPLLFILLVGYLIPQQVVDSKQPQNFIKNNFSELSSSRYVLTDSVGVAAGLAWELKRSDILMFS
EKGELTYGLAYPDSQDNYISNDDFPTWLAQARKEGDVSLVVQLAKNEALPAHLPPADKVNLMNRLALLWYQKTP

Sequences:

>Translated_554_residues
MKLLKDSGAALLALFFVLVYLLPVNSRLLWQPDETRYAEISREMLQRGDWVVPYFMDIRYFEKPVAGYWFNNISQWIFGD
SNFAVRFGSIFSTALSAVLVYWLATLLWRNRSTSVLATLIYLSFLLVFGIGTYAVLDPMISLWLTAAMVSFYLTLKAENW
QQKVGAYALLGVACGMGFMTKGFLALAVPVIAVLPIVIQQKRIKDLVVFGPIAIVCAVLLSLPWALAIAQREPDFWNYFF
WVEHIQRFAEASAQHKSPIWYYLPILCIGVLPWLGLLPGALFKGWRERATKPELFFLLSWVVMPLLFFSVAKGKLPTYIL
PCMAPLSLLMAAYATDCANNIRMRALKINGVINLLFGVACALVIVVIGLGLVKDIVAYGPQENQKVWLGVLAFAGWGVTG
FITLRNNARNWRWAAACPLLFILLVGYLIPQQVVDSKQPQNFIKNNFSELSSSRYVLTDSVGVAAGLAWELKRSDILMFS
EKGELTYGLAYPDSQDNYISNDDFPTWLAQARKEGDVSLVVQLAKNEALPAHLPPADKVNLMNRLALLWYQKTP
>Mature_554_residues
MKLLKDSGAALLALFFVLVYLLPVNSRLLWQPDETRYAEISREMLQRGDWVVPYFMDIRYFEKPVAGYWFNNISQWIFGD
SNFAVRFGSIFSTALSAVLVYWLATLLWRNRSTSVLATLIYLSFLLVFGIGTYAVLDPMISLWLTAAMVSFYLTLKAENW
QQKVGAYALLGVACGMGFMTKGFLALAVPVIAVLPIVIQQKRIKDLVVFGPIAIVCAVLLSLPWALAIAQREPDFWNYFF
WVEHIQRFAEASAQHKSPIWYYLPILCIGVLPWLGLLPGALFKGWRERATKPELFFLLSWVVMPLLFFSVAKGKLPTYIL
PCMAPLSLLMAAYATDCANNIRMRALKINGVINLLFGVACALVIVVIGLGLVKDIVAYGPQENQKVWLGVLAFAGWGVTG
FITLRNNARNWRWAAACPLLFILLVGYLIPQQVVDSKQPQNFIKNNFSELSSSRYVLTDSVGVAAGLAWELKRSDILMFS
EKGELTYGLAYPDSQDNYISNDDFPTWLAQARKEGDVSLVVQLAKNEALPAHLPPADKVNLMNRLALLWYQKTP

Specific function: Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides

COG id: COG1807

COG function: function code M; 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 83 family

Homologues:

Organism=Escherichia coli, GI1788591, Length=538, Percent_Identity=53.9033457249071, Blast_Score=593, Evalue=1e-171,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARNT_YERP3 (A7FHH6)

Other databases:

- EMBL:   CP000720
- RefSeq:   YP_001400704.1
- ProteinModelPortal:   A7FHH6
- STRING:   A7FHH6
- GeneID:   5387737
- GenomeReviews:   CP000720_GR
- KEGG:   ypi:YpsIP31758_1729
- eggNOG:   COG1807
- HOGENOM:   HBG298640
- OMA:   ASMAFES
- ProtClustDB:   PRK13279
- BioCyc:   YPSE349747:YPSIP31758_1729-MONOMER
- HAMAP:   MF_01165
- InterPro:   IPR022839
- InterPro:   IPR003342

Pfam domain/function: PF02366 PMT

EC number: =2.4.2.43

Molecular weight: Translated: 62289; Mature: 62289

Theoretical pI: Translated: 9.23; Mature: 9.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xeb620e8)-; HASH(0xf26ef80)-; HASH(0xf9e8a8c)-; HASH(0xf150dc8)-; HASH(0xf35d50c)-; HASH(0xe4bbd3c)-; HASH(0xe998290)-; HASH(0xe9b9b60)-; HASH(0xcadebe4)-; HASH(0xfad2150)-; HASH(0xc49cff8)-;

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLLKDSGAALLALFFVLVYLLPVNSRLLWQPDETRYAEISREMLQRGDWVVPYFMDIRY
CCCCCCCCHHHHHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHCCCEEEHHHHHHHH
FEKPVAGYWFNNISQWIFGDSNFAVRFGSIFSTALSAVLVYWLATLLWRNRSTSVLATLI
HHCCHHHHHHHCCHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
YLSFLLVFGIGTYAVLDPMISLWLTAAMVSFYLTLKAENWQQKVGAYALLGVACGMGFMT
HHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHCHHHHH
KGFLALAVPVIAVLPIVIQQKRIKDLVVFGPIAIVCAVLLSLPWALAIAQREPDFWNYFF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
WVEHIQRFAEASAQHKSPIWYYLPILCIGVLPWLGLLPGALFKGWRERATKPELFFLLSW
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
VVMPLLFFSVAKGKLPTYILPCMAPLSLLMAAYATDCANNIRMRALKINGVINLLFGVAC
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHH
ALVIVVIGLGLVKDIVAYGPQENQKVWLGVLAFAGWGVTGFITLRNNARNWRWAAACPLL
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCEEEEEEEECCCCCCHHHHHHHHH
FILLVGYLIPQQVVDSKQPQNFIKNNFSELSSSRYVLTDSVGVAAGLAWELKRSDILMFS
HHHHHHHHHHHHHHCCCCCHHHHHCCHHHHCCCCEEEECCCHHHHHHHHEECCCCEEEEE
EKGELTYGLAYPDSQDNYISNDDFPTWLAQARKEGDVSLVVQLAKNEALPAHLPPADKVN
CCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHCCCCHHHHHEEHHCCCCCCCCCCCHHHH
LMNRLALLWYQKTP
HHHHHHHHHCCCCH
>Mature Secondary Structure
MKLLKDSGAALLALFFVLVYLLPVNSRLLWQPDETRYAEISREMLQRGDWVVPYFMDIRY
CCCCCCCCHHHHHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHCCCEEEHHHHHHHH
FEKPVAGYWFNNISQWIFGDSNFAVRFGSIFSTALSAVLVYWLATLLWRNRSTSVLATLI
HHCCHHHHHHHCCHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
YLSFLLVFGIGTYAVLDPMISLWLTAAMVSFYLTLKAENWQQKVGAYALLGVACGMGFMT
HHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHCHHHHH
KGFLALAVPVIAVLPIVIQQKRIKDLVVFGPIAIVCAVLLSLPWALAIAQREPDFWNYFF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
WVEHIQRFAEASAQHKSPIWYYLPILCIGVLPWLGLLPGALFKGWRERATKPELFFLLSW
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
VVMPLLFFSVAKGKLPTYILPCMAPLSLLMAAYATDCANNIRMRALKINGVINLLFGVAC
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHH
ALVIVVIGLGLVKDIVAYGPQENQKVWLGVLAFAGWGVTGFITLRNNARNWRWAAACPLL
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCEEEEEEEECCCCCCHHHHHHHHH
FILLVGYLIPQQVVDSKQPQNFIKNNFSELSSSRYVLTDSVGVAAGLAWELKRSDILMFS
HHHHHHHHHHHHHHCCCCCHHHHHCCHHHHCCCCEEEECCCHHHHHHHHEECCCCEEEEE
EKGELTYGLAYPDSQDNYISNDDFPTWLAQARKEGDVSLVVQLAKNEALPAHLPPADKVN
CCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHCCCCHHHHHEEHHCCCCCCCCCCCHHHH
LMNRLALLWYQKTP
HHHHHHHHHCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA