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The map label for this gene is cheB [H]

Identifier: 22125733

GI number: 22125733

Start: 2030847

End: 2031899

Strand: Direct

Name: cheB [H]

Synonym: y1841

Alternate gene names: 22125733

Gene position: 2030847-2031899 (Clockwise)

Preceding gene: 22125732

Following gene: 22125735

Centisome position: 44.14

GC content: 53.09

Gene sequence:

>1053_bases
GTGATGAGTAAAATCAGAGTATTGTGTGTTGATGATTCTGCATTAATGCGTCAGCTAATGACTGAGATTATTAACAGTCA
CCCGGATATGGAGATGGTTGCTGCGGCACAGGATCCGTTGGTTGCCCGTGATTTGATCAAAAAATTTAATCCACAAGTTT
TGACGCTTGACGTGGAAATGCCTCGCATGGATGGCTTGGATTTTCTCGAGAAATTGATGCGTCTACGGCCCATGCCGGTG
GTGATGGTGTCTTCCCTAACGGGTAAAAACTCCGAAATAACCATGCGGGCGTTGGAGTTGGGGGCGATTGATTTTGTCAC
CAAACCTCAGTTAGGGATCCGCGAAGGAATGCTGGCTTACAGCGAACTGATTGCCGATAAGATCCGCACGGCGGCTAAGG
CTCGTTTACCACAGCGCGTCCTGGAAAATAAACCGGCGATGCTCAGCCATACCCCATTGCTCAGCAGTGAAAAATTGATC
GCCATTGGGGCATCAACTGGCGGTACTGAGGCGATTCGTGCGGTATTACAGCCTTTGCCACCAACCAGTCCGGCATTGCT
GATCACTCAGCATATGCCGCCGGGATTTACCCGTTCGTTTGCTGAACGCTTGAATAAACTGTGCCAAATCACGGTAAAAG
AAGCAGAGGATGGCGAGCGAGTATTACCGGGACATGCCTATATTGCACCCGGTGATCGGCACTTGGAACTGGCCCGGAGT
GGTGCCAACTACCAGGTGCGGATCCATGATGGACCCGCGGTTAATCGTCACCGTCCTTCGGTTGACGTTCTTTTCCGTTC
GGTGGCGCAGTATGCCGGGCGCAATGCGGTCGGGGTGATCCTCACGGGGATGGGCAATGATGGAGCCGCTGGCTTGCTGG
AGATGCACCGGGCGGGTGCCTACACCCTCGCGCAAAATGAGGCCAGCTGCGTGGTCTTTGGTATGCCACGTGAGGCGATT
GCGATGGGGGGGGTTAATGACGTCGTGGAGTTGAACCAAATAAGTCAGCGGATGTTGGCGCAGATCAGTAGTGGTCAAGC
CCTTCGCATATAG

Upstream 100 bases:

>100_bases
CAGGCGGCCTGATGTTCGCTGGCCACTCGGAGAATTTCAGCCAGATCAGTCGGGAATTCTATTTGCGCGGGCAGACCGTT
TATGGGCTGACCAAGGAGAG

Downstream 100 bases:

>100_bases
AGATCTCATTATGATGGGGGTCTATAAATTATTTTTCCGATAACCATCGGGCTATTGCATTTAATCGCTCAGCGCTGAGC
AACAAACTTTAGGAGTGGGT

Product: chemotaxis-specific methylesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 350; Mature: 350

Protein sequence:

>350_residues
MMSKIRVLCVDDSALMRQLMTEIINSHPDMEMVAAAQDPLVARDLIKKFNPQVLTLDVEMPRMDGLDFLEKLMRLRPMPV
VMVSSLTGKNSEITMRALELGAIDFVTKPQLGIREGMLAYSELIADKIRTAAKARLPQRVLENKPAMLSHTPLLSSEKLI
AIGASTGGTEAIRAVLQPLPPTSPALLITQHMPPGFTRSFAERLNKLCQITVKEAEDGERVLPGHAYIAPGDRHLELARS
GANYQVRIHDGPAVNRHRPSVDVLFRSVAQYAGRNAVGVILTGMGNDGAAGLLEMHRAGAYTLAQNEASCVVFGMPREAI
AMGGVNDVVELNQISQRMLAQISSGQALRI

Sequences:

>Translated_350_residues
MMSKIRVLCVDDSALMRQLMTEIINSHPDMEMVAAAQDPLVARDLIKKFNPQVLTLDVEMPRMDGLDFLEKLMRLRPMPV
VMVSSLTGKNSEITMRALELGAIDFVTKPQLGIREGMLAYSELIADKIRTAAKARLPQRVLENKPAMLSHTPLLSSEKLI
AIGASTGGTEAIRAVLQPLPPTSPALLITQHMPPGFTRSFAERLNKLCQITVKEAEDGERVLPGHAYIAPGDRHLELARS
GANYQVRIHDGPAVNRHRPSVDVLFRSVAQYAGRNAVGVILTGMGNDGAAGLLEMHRAGAYTLAQNEASCVVFGMPREAI
AMGGVNDVVELNQISQRMLAQISSGQALRI
>Mature_350_residues
MMSKIRVLCVDDSALMRQLMTEIINSHPDMEMVAAAQDPLVARDLIKKFNPQVLTLDVEMPRMDGLDFLEKLMRLRPMPV
VMVSSLTGKNSEITMRALELGAIDFVTKPQLGIREGMLAYSELIADKIRTAAKARLPQRVLENKPAMLSHTPLLSSEKLI
AIGASTGGTEAIRAVLQPLPPTSPALLITQHMPPGFTRSFAERLNKLCQITVKEAEDGERVLPGHAYIAPGDRHLELARS
GANYQVRIHDGPAVNRHRPSVDVLFRSVAQYAGRNAVGVILTGMGNDGAAGLLEMHRAGAYTLAQNEASCVVFGMPREAI
AMGGVNDVVELNQISQRMLAQISSGQALRI

Specific function: Involved in the modulation of the chemotaxis system; catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR [H]

COG id: COG2201

COG function: function code NT; Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788192, Length=349, Percent_Identity=84.5272206303725, Blast_Score=602, Evalue=1e-174,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR008248
- InterPro:   IPR000673
- InterPro:   IPR001789 [H]

Pfam domain/function: PF01339 CheB_methylest; PF00072 Response_reg [H]

EC number: =3.1.1.61 [H]

Molecular weight: Translated: 38114; Mature: 38114

Theoretical pI: Translated: 8.48; Mature: 8.48

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50122 CHEB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
5.7 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
5.7 %Met     (Mature Protein)
6.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMSKIRVLCVDDSALMRQLMTEIINSHPDMEMVAAAQDPLVARDLIKKFNPQVLTLDVEM
CCCCEEEEEECCHHHHHHHHHHHHHCCCCCEEHHHCCCCHHHHHHHHHCCCCEEEEEECC
PRMDGLDFLEKLMRLRPMPVVMVSSLTGKNSEITMRALELGAIDFVTKPQLGIREGMLAY
CCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCEEEEEEHHCCEEEECCCCCCHHHHHHHH
SELIADKIRTAAKARLPQRVLENKPAMLSHTPLLSSEKLIAIGASTGGTEAIRAVLQPLP
HHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCEEEEECCCCCHHHHHHHHHCCC
PTSPALLITQHMPPGFTRSFAERLNKLCQITVKEAEDGERVLPGHAYIAPGDRHLELARS
CCCCEEEEEECCCCCHHHHHHHHHHHHHEEEEECCCCCCEECCCCEEECCCCCHHHHHHC
GANYQVRIHDGPAVNRHRPSVDVLFRSVAQYAGRNAVGVILTGMGNDGAAGLLEMHRAGA
CCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEEEECCCCCCHHHHHHHHCCC
YTLAQNEASCVVFGMPREAIAMGGVNDVVELNQISQRMLAQISSGQALRI
EEEECCCCCEEEEECCHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCEECC
>Mature Secondary Structure
MMSKIRVLCVDDSALMRQLMTEIINSHPDMEMVAAAQDPLVARDLIKKFNPQVLTLDVEM
CCCCEEEEEECCHHHHHHHHHHHHHCCCCCEEHHHCCCCHHHHHHHHHCCCCEEEEEECC
PRMDGLDFLEKLMRLRPMPVVMVSSLTGKNSEITMRALELGAIDFVTKPQLGIREGMLAY
CCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCEEEEEEHHCCEEEECCCCCCHHHHHHHH
SELIADKIRTAAKARLPQRVLENKPAMLSHTPLLSSEKLIAIGASTGGTEAIRAVLQPLP
HHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCEEEEECCCCCHHHHHHHHHCCC
PTSPALLITQHMPPGFTRSFAERLNKLCQITVKEAEDGERVLPGHAYIAPGDRHLELARS
CCCCEEEEEECCCCCHHHHHHHHHHHHHEEEEECCCCCCEECCCCEEECCCCCHHHHHHC
GANYQVRIHDGPAVNRHRPSVDVLFRSVAQYAGRNAVGVILTGMGNDGAAGLLEMHRAGA
CCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEEEECCCCCCHHHHHHHHCCC
YTLAQNEASCVVFGMPREAIAMGGVNDVVELNQISQRMLAQISSGQALRI
EEEECCCCCEEEEECCHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA