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The map label for this gene is qorA [H]

Identifier: 22125710

GI number: 22125710

Start: 1993957

End: 1995003

Strand: Reverse

Name: qorA [H]

Synonym: y1816

Alternate gene names: 22125710

Gene position: 1995003-1993957 (Counterclockwise)

Preceding gene: 22125711

Following gene: 22125709

Centisome position: 43.36

GC content: 50.33

Gene sequence:

>1047_bases
TTGCTGACTCACCGCCACGCCATTAAGAGGAATATTATGACATTGTTAACTCATCTCCCTGCAAACATGGTCGCGATTGA
AATCACCCAGTTTGGTGGACCAGAGGTATTAGTCCCAGCCAAACGGCCAACCCCCATGCCAGCCGCTGGCGAAATTTTGG
TGAAAGTATCTGCCGCTGGAGTGAATCGGCCTGATGTCATGCAACGTCGTGGGCAATATGCGCCCCCACCGGGTGCCTCA
GATATTCCCGGATTAGAAGTTGCCGGCGAAGTGGTCGCCACTGCCGCGGATGTCACGCGTTTTAAAATTGGGGACAACGT
CTGCGGGCTGATCGCGGGCGGCGGTTATGCGCAGTACTGTGTCATACATGAAACCAATGCGTTACCGATCCCTCAGGGGC
TTAGCGCCATTGAAGCCGCCGCACTTCCTGAAACGTTCTTTACTGTCTGGACCAATTTATTCCAACGTGGTCACTTCACT
GCAGGCGAAACCGTACTCATTCATGGCGGTTCTTCAGGCATAGGGACAACAGCTATTTTGCTGAGCAAAGCTTTTGGCGC
GGCAACGGTTATTGTGACGGTAGGTTCGGAAGAGAAACGTCAGGCGTGCCTGAATCTGGGCGCAGATATTGCTATTAATT
ATCACACTCAGGATTTTGTCGCTGAAACCAAGCGGGCAACCGCCGGTAAAGGGGCAGATGTGATTGTCGATTTAATTGCT
GGTGATTATGTCGCACGCAATTATGACGCAGCGGCGATGAATGGCCGTATTGTTCAGATTGGTACACAAAATGGTCATGC
CAAAGACCTTAACCTGATGCTGATGTTAATAAAACGTCTAACACATACCGGCTCCACACTGCGCTCCCGTACAGTTGCAG
AGAAAGCATTAATTGCCAACGAACTTGAACAACACGTTTGGCCACTGCTGAGTGAGGGTAAAATGAAACCACAGATTTTC
AGTACCTTCCCGCTGGAAGCCGCCGCAAAAGCCCATGAACTAATGGAAAGCAGTACACACATAGGTAAAATTGTTCTCAC
CGCTTGA

Upstream 100 bases:

>100_bases
TCACTCTATGAATTTTTTCCATTACACGACTAAGATACCCTTTTAGCCATTATCATCTTGAGTCACTACCACTTACTATC
ATCTTTGGCCACAGCCATCA

Downstream 100 bases:

>100_bases
GCCATAAATGCCTATTATCAGCAGGATACGATACCCAAAATAATTCAAGATGCAGGTAGTCAGCAACCGAGCAATCCCCA
GGAGCTTAGATAACTCAGTG

Product: oxidoreductase

Products: NA

Alternate protein names: NADPH:quinone reductase 1; Zeta-crystallin homolog protein [H]

Number of amino acids: Translated: 348; Mature: 348

Protein sequence:

>348_residues
MLTHRHAIKRNIMTLLTHLPANMVAIEITQFGGPEVLVPAKRPTPMPAAGEILVKVSAAGVNRPDVMQRRGQYAPPPGAS
DIPGLEVAGEVVATAADVTRFKIGDNVCGLIAGGGYAQYCVIHETNALPIPQGLSAIEAAALPETFFTVWTNLFQRGHFT
AGETVLIHGGSSGIGTTAILLSKAFGAATVIVTVGSEEKRQACLNLGADIAINYHTQDFVAETKRATAGKGADVIVDLIA
GDYVARNYDAAAMNGRIVQIGTQNGHAKDLNLMLMLIKRLTHTGSTLRSRTVAEKALIANELEQHVWPLLSEGKMKPQIF
STFPLEAAAKAHELMESSTHIGKIVLTA

Sequences:

>Translated_348_residues
MLTHRHAIKRNIMTLLTHLPANMVAIEITQFGGPEVLVPAKRPTPMPAAGEILVKVSAAGVNRPDVMQRRGQYAPPPGAS
DIPGLEVAGEVVATAADVTRFKIGDNVCGLIAGGGYAQYCVIHETNALPIPQGLSAIEAAALPETFFTVWTNLFQRGHFT
AGETVLIHGGSSGIGTTAILLSKAFGAATVIVTVGSEEKRQACLNLGADIAINYHTQDFVAETKRATAGKGADVIVDLIA
GDYVARNYDAAAMNGRIVQIGTQNGHAKDLNLMLMLIKRLTHTGSTLRSRTVAEKALIANELEQHVWPLLSEGKMKPQIF
STFPLEAAAKAHELMESSTHIGKIVLTA
>Mature_348_residues
MLTHRHAIKRNIMTLLTHLPANMVAIEITQFGGPEVLVPAKRPTPMPAAGEILVKVSAAGVNRPDVMQRRGQYAPPPGAS
DIPGLEVAGEVVATAADVTRFKIGDNVCGLIAGGGYAQYCVIHETNALPIPQGLSAIEAAALPETFFTVWTNLFQRGHFT
AGETVLIHGGSSGIGTTAILLSKAFGAATVIVTVGSEEKRQACLNLGADIAINYHTQDFVAETKRATAGKGADVIVDLIA
GDYVARNYDAAAMNGRIVQIGTQNGHAKDLNLMLMLIKRLTHTGSTLRSRTVAEKALIANELEQHVWPLLSEGKMKPQIF
STFPLEAAAKAHELMESSTHIGKIVLTA

Specific function: Unknown

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI22538446, Length=331, Percent_Identity=40.785498489426, Blast_Score=228, Evalue=6e-60,
Organism=Homo sapiens, GI22538444, Length=331, Percent_Identity=40.785498489426, Blast_Score=228, Evalue=6e-60,
Organism=Homo sapiens, GI194239674, Length=330, Percent_Identity=30.6060606060606, Blast_Score=153, Evalue=3e-37,
Organism=Homo sapiens, GI13236495, Length=330, Percent_Identity=30.6060606060606, Blast_Score=153, Evalue=3e-37,
Organism=Homo sapiens, GI18379349, Length=312, Percent_Identity=29.1666666666667, Blast_Score=124, Evalue=1e-28,
Organism=Homo sapiens, GI194239676, Length=330, Percent_Identity=28.7878787878788, Blast_Score=120, Evalue=1e-27,
Organism=Homo sapiens, GI24308257, Length=341, Percent_Identity=25.5131964809384, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI28557745, Length=228, Percent_Identity=32.8947368421053, Blast_Score=92, Evalue=5e-19,
Organism=Homo sapiens, GI41872631, Length=301, Percent_Identity=27.5747508305648, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI197927207, Length=199, Percent_Identity=28.643216080402, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI47519420, Length=370, Percent_Identity=26.7567567567568, Blast_Score=77, Evalue=3e-14,
Organism=Escherichia coli, GI1790485, Length=325, Percent_Identity=32, Blast_Score=122, Evalue=4e-29,
Organism=Escherichia coli, GI1787863, Length=345, Percent_Identity=26.9565217391304, Blast_Score=69, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17507255, Length=327, Percent_Identity=26.2996941896024, Blast_Score=97, Evalue=8e-21,
Organism=Caenorhabditis elegans, GI212642053, Length=308, Percent_Identity=27.9220779220779, Blast_Score=87, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6319520, Length=334, Percent_Identity=27.2455089820359, Blast_Score=100, Evalue=4e-22,
Organism=Saccharomyces cerevisiae, GI6324486, Length=337, Percent_Identity=24.3323442136499, Blast_Score=74, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6323729, Length=334, Percent_Identity=23.9520958083832, Blast_Score=72, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6323961, Length=284, Percent_Identity=23.943661971831, Blast_Score=70, Evalue=7e-13,
Organism=Drosophila melanogaster, GI221330659, Length=304, Percent_Identity=28.6184210526316, Blast_Score=99, Evalue=5e-21,
Organism=Drosophila melanogaster, GI19920632, Length=304, Percent_Identity=28.6184210526316, Blast_Score=98, Evalue=7e-21,
Organism=Drosophila melanogaster, GI24581345, Length=317, Percent_Identity=26.813880126183, Blast_Score=92, Evalue=8e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR002364 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.6.5.5 [H]

Molecular weight: Translated: 36922; Mature: 36922

Theoretical pI: Translated: 7.76; Mature: 7.76

Prosite motif: PS00962 RIBOSOMAL_S2_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTHRHAIKRNIMTLLTHLPANMVAIEITQFGGPEVLVPAKRPTPMPAAGEILVKVSAAG
CCCCHHHHHHHHHHHHHHCCCCEEEEEEEECCCCEEEEECCCCCCCCCCCEEEEEEECCC
VNRPDVMQRRGQYAPPPGASDIPGLEVAGEVVATAADVTRFKIGDNVCGLIAGGGYAQYC
CCCCHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHEEEEECCCEEEEEECCCEEEEE
VIHETNALPIPQGLSAIEAAALPETFFTVWTNLFQRGHFTAGETVLIHGGSSGIGTTAIL
EEECCCCCCCCCCHHHHHHHHCHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCHHHHHH
LSKAFGAATVIVTVGSEEKRQACLNLGADIAINYHTQDFVAETKRATAGKGADVIVDLIA
HHHHCCCEEEEEEECCCHHHHHHHCCCCCEEEEECCHHHHHHHHHHCCCCCCHHEEEEHH
GDYVARNYDAAAMNGRIVQIGTQNGHAKDLNLMLMLIKRLTHTGSTLRSRTVAEKALIAN
CCHHHCCCCCHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
ELEQHVWPLLSEGKMKPQIFSTFPLEAAAKAHELMESSTHIGKIVLTA
HHHHHHHHHHHCCCCCCHHEECCCHHHHHHHHHHHHCCCCCCEEEEEC
>Mature Secondary Structure
MLTHRHAIKRNIMTLLTHLPANMVAIEITQFGGPEVLVPAKRPTPMPAAGEILVKVSAAG
CCCCHHHHHHHHHHHHHHCCCCEEEEEEEECCCCEEEEECCCCCCCCCCCEEEEEEECCC
VNRPDVMQRRGQYAPPPGASDIPGLEVAGEVVATAADVTRFKIGDNVCGLIAGGGYAQYC
CCCCHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHEEEEECCCEEEEEECCCEEEEE
VIHETNALPIPQGLSAIEAAALPETFFTVWTNLFQRGHFTAGETVLIHGGSSGIGTTAIL
EEECCCCCCCCCCHHHHHHHHCHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCHHHHHH
LSKAFGAATVIVTVGSEEKRQACLNLGADIAINYHTQDFVAETKRATAGKGADVIVDLIA
HHHHCCCEEEEEEECCCHHHHHHHCCCCCEEEEECCHHHHHHHHHHCCCCCCHHEEEEHH
GDYVARNYDAAAMNGRIVQIGTQNGHAKDLNLMLMLIKRLTHTGSTLRSRTVAEKALIAN
CCHHHCCCCCHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
ELEQHVWPLLSEGKMKPQIFSTFPLEAAAKAHELMESSTHIGKIVLTA
HHHHHHHHHHHCCCCCCHHEECCCHHHHHHHHHHHHCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503; 7602590 [H]